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List of works by Helen M. Colhoun

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

scientific article published on 27 April 2018

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

scientific article

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

scientific article

A genetic link between type 2 diabetes and prostate cancer

scientific article published on 12 August 2008

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

scientific article published on March 2015

A noninvasive measure of baroreflex sensitivity without blood pressure measurement.

scientific article published in March 2002

A novel common variant −181 G insertion in the promoter of the gene for phospholipid transfer protein

scientific article published in May 2005

Achieved levels of HbA1c and likelihood of hospital admission in people with type 1 diabetes in the Scottish population: a study from the Scottish Diabetes Research Network Epidemiology Group

scientific article

Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects

scientific article published in August 2002

After FIELD: should fibrates be used to prevent cardiovascular disease in diabetes?

scientific article published in November 2005

All-cause mortality rates in patients with type 1 diabetes mellitus compared with a non-diabetic population from the UK general practice research database, 1992-1999.

scientific article published on 24 January 2006

Analysis of efficacy and safety in patients aged 65-75 years at randomization: Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article

Antibodies to periodontal pathogens and coronary artery calcification in type 1 diabetic and nondiabetic subjects

scientific article published on 01 February 2008

Apolipoproteins, cardiovascular risk and statin response in type 2 diabetes: the Collaborative Atorvastatin Diabetes Study (CARDS)

scientific article published on 17 December 2008

Apolipoproteins, cardiovascular risk and statin response in type 2 diabetes: the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article published on 30 October 2008

Area-based socioeconomic status, type 2 diabetes and cardiovascular mortality in Scotland

scientific article

Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes.

scientific article

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis

scientific article published on March 2012

Baseline characteristics in the Collaborative AtoRvastatin Diabetes Study (CARDS) in patients with Type 2 diabetes.

scientific article

Biomarker panels associated with progression of renal disease in type 1 diabetes

scientific article published on 20 June 2019

Biomarkers of rapid chronic kidney disease progression in type 2 diabetes

scientific article published on 22 July 2015

Blood pressure in women using oral contraceptives

scientific article published in October 1997

Blood pressure screening, management and control in England

scientific article published in June 1998

C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification

scientific article published in October 2002

Cardiovascular Disease, Cancer, and Mortality Among People With Type 2 Diabetes and Alcoholic or Nonalcoholic Fatty Liver Disease Hospital Admission

scientific article published on 22 November 2017

Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis.

scientific article published on 10 October 2018

Cardiovascular risk factors as determinants of endothelium-dependent and endothelium-independent vascular reactivity in the general population ⬇️

scientific article published on December 1, 2001

Cause-specific mortality in Scottish patients with colorectal cancer with and without type 2 diabetes (2000–2007)

article

Characterizing genetic variants for clinical action

scientific article

Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications

scientific article published on 10 December 2020

Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

scientific article

Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes

scientific article published on 31 October 2012

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

scientific article

Comparison of neuropsychological functioning and emotional processing in major depression and social anxiety disorder subjects, and matched healthy controls

scientific article published on 18 June 2012

Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes

scientific article published on 08 January 2020

Confirmation needed for genes for hypertension

scientific article published in The Lancet

Contemporary risk of hip fracture in type 1 and type 2 diabetes: a national registry study from Scotland

scientific article

Coronary artery calcification and aortic pulse wave velocity in chronic kidney disease patients

scientific article

Coronary heart disease in women: why the disproportionate risk?

scientific article

Cost-effectiveness of primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes: results from the Collaborative Atorvastatin Diabetes Study (CARDS)

scientific article published on 31 January 2007

Development and Validation of a Model to Predict Absolute Vascular Risk Reduction by Moderate-Intensity Statin Therapy in Individual Patients With Type 2 Diabetes Mellitus: The Anglo Scandinavian Cardiac Outcomes Trial, Antihypertensive and Lipid-Lo

scientific article published on 11 May 2016

Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland

scientific article published on 23 January 2020

Diabetic retinopathy at diagnosis of type 2 diabetes in Scotland.

scientific article

Differences in HDL-cholesterol:apoA-I + apoA-II ratio and apoE phenotype with albuminuric status in Type I diabetic patients.

scientific article published in November 2000

Do men develop type 2 diabetes at lower body mass indices than women?

scientific article

Earthquake Brain: Altered Recognition and Misclassification of Facial Expressions Are Related to Trauma Exposure but Not Posttraumatic Stress Disorder

scientific article published on 12 December 2017

Earthquake brain: Impairment of spatial memory following long-term earthquake-related stress

scientific article published in July 2018

Effect of atorvastatin on C-reactive protein and benefits for cardiovascular disease in patients with type 2 diabetes: analyses from the Collaborative Atorvastatin Diabetes Trial

scientific article published on 22 April 2015

Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS)

scientific article

Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group

scientific article

Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial

scientific article published on 01 July 2019

Effects of atorvastatin on kidney outcomes and cardiovascular disease in patients with diabetes: an analysis from the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article published on 21 June 2009

Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials

scientific article

Efficacy and safety of adding alirocumab to rosuvastatin versus adding ezetimibe or doubling the rosuvastatin dose in high cardiovascular-risk patients: The ODYSSEY OPTIONS II randomized trial

scientific article published on 14 November 2015

Efficacy and safety of alirocumab as add-on therapy in high-cardiovascular-risk patients with hypercholesterolemia not adequately controlled with atorvastatin (20 or 40 mg) or rosuvastatin (10 or 20 mg): design and rationale of the ODYSSEY OPTIONS S

scientific article

Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated doses of statins: the ODYSSEY COMBO II randomized controlled trial

scientific article published on 16 February 2015

Efficacy and safety of alirocumab, a fully human PCSK9 monoclonal antibody, in high cardiovascular risk patients with poorly controlled hypercholesterolemia on maximally tolerated doses of statins: rationale and design of the ODYSSEY COMBO I and II t

article

Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab among high cardiovascular risk patients on maximally tolerated statin therapy: The ODYSSEY COMBO I study

article

Eicosapentaenoic acid for prevention of major coronary events

scientific article published in The Lancet

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes

scientific article published on 07 May 2015

Endothelium-dependent and -independent vascular dysfunction in type 1 diabetes: role of conventional risk factors, sex, and glycemic control

scientific article published on 24 April 2003

Erratum to: Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013.

scientific article published on 5 September 2016

Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456

scientific article published on 27 April 2020

Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010

scientific article

Ethnic differences in glycaemic control in people with type 2 diabetes mellitus living in Scotland

scientific article

Ethnicity and risk of cardiovascular disease (CVD): 4.8 year follow-up of patients with type 2 diabetes living in Scotland

scientific article published on 12 February 2015

Evaluation of "stratify and shield" as a policy option for ending the COVID-19 lockdown in the UK

scientific article published on 30 April 2020

Gender differences in accessing cardiac surgery across England: a cross-sectional analysis of the health survey for England

scientific article published in December 1998

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

scientific article

Glycaemic control trends in people with type 1 diabetes in Scotland 2004-2016

scientific article published on 18 May 2019

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

scientific article published on 19 February 2020

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

scientific article

Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering drugs.

scientific article

Human cytomegalovirus seropositivity is associated with impaired vascular function

scientific article published on 04 August 2003

Insight into the nature of the CRP-coronary event association using Mendelian randomization

scientific article

Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks? ⬇️

scientific article published on April 24, 2013

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Investigation of known estimated glomerular filtration rate loci in patients with type 2 diabetes.

scientific article

LADA and CARDS: A Prospective Study of Clinical Outcome in Established Adult-Onset Autoimmune Diabetes

scientific article published on 10 April 2014

Letters to the Editor

scientific article published in October 1999

Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis

scientific article published on 21 August 2013

Lipid goals in metabolic syndrome and diabetes

scientific article published on October 2007

Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study

article

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

scientific article

Modelling cumulative exposure for inference about drug effects in observational studies

scientific article

Modelling the cost-effectiveness of adopting risk-stratified approaches to extended screening intervals in the national diabetic retinopathy screening programme in Scotland.

scientific article published on 4 April 2016

Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia: Results of a 24week, double-blind, randomized Phase 3 trial

article

Mortality in people with Type 2 diabetes in the UK

scientific article published in May 2006

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

scientific article published on 28 November 2018

N-Glycan Profile and Kidney Disease in Type 1 Diabetes

scientific article published on 16 November 2017

New susceptibility loci associated with kidney disease in type 1 diabetes

scientific article

Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment - systematic review and modelling of progression and cost-effectiveness

scientific article published on February 2014

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant

scientific article

Parental history of hypertension and parental history of diabetes and microvascular complications in insulin-dependent diabetes mellitus: the EURODIAB IDDM complications study ⬇️

scientific article published on May 1, 1998

Performance of Cardiovascular Disease Risk Scores in People Diagnosed With Type 2 Diabetes: External Validation Using Data From the National Scottish Diabetes Register

scientific article published on 12 July 2018

Pharmacoepidemiology: Using randomised control trials and observational studies in clinical decision-making

scientific article published on 24 July 2019

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis

scientific article published on 07 December 2014

Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification

scientific article

Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus

scientific article published on 05 December 2019

Predictors of new-onset diabetes in patients treated with atorvastatin: results from 3 large randomized clinical trials

scientific article

Prescribing Paradigm Shift? Applying the 2019 European Society of Cardiology-Led Guidelines on Diabetes, Prediabetes, and Cardiovascular Disease to Assess Eligibility for Sodium-Glucose Cotransporter 2 Inhibitors or Glucagon-Like Peptide 1 Receptor

scientific article published on 24 June 2020

Problems of reporting genetic associations with complex outcomes

scientific article

Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes

scientific article

Rapid Epidemiological Analysis of Comorbidities and Treatments as risk factors for COVID-19 in Scotland (REACT-SCOT): A population-based case-control study

scientific article published on 20 October 2020

Rapid emergence of effect of atorvastatin on cardiovascular outcomes in the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article

Rates of referable eye disease in the Scottish National Diabetic Retinopathy Screening Programme.

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Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: a nationwide study

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Reservoir Pressure Integral Is Independently Associated With the Reduction in Renal Function in Older Adults

scientific article published in 2022

Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study

scientific article

Risk of myocardial infarction in men and women with type 2 diabetes in the UK: a cohort study using the General Practice Research Database

scientific article published on 26 June 2008

Risk of stroke in people with type 2 diabetes in the UK: a study using the General Practice Research Database

scientific article published on 27 October 2006

Risk stratification for diabetic eye screening. Reply to Stratton I. M. and Aldington S. J. [letter].

scientific article published on 8 November 2013

Socio-economic differences in cardiovascular disease risk factor prevalence in people with type 2 diabetes in Scotland: a cross-sectional study

scientific article published on 18 March 2020

Socio-economic status and mortality in people with type 1 diabetes in Scotland 2006-2015: a retrospective cohort study

scientific article published on 22 January 2020

Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article published on 26 September 2007

Study of agreement between LDL size as measured by nuclear magnetic resonance and gradient gel electrophoresis

scientific article published in March 2004

Targets of statin therapy: LDL cholesterol, non-HDL cholesterol, and apolipoprotein B in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article published on 15 January 2009

The Genetic Landscape of Renal Complications in Type 1 Diabetes

scientific article

The big picture on obesity and insulin resistance**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology

scientific article published in September 2002

The cost of prevalent and incident cardiovascular disease in people with type 2 diabetes in Scotland: data from the Scottish Care Information-Diabetes Collaboration

scientific article published on 28 January 2020

The effect of DAFNE education, continuous subcutaneous insulin infusion, or both in a population with type 1 diabetes in Scotland

scientific article published on 23 December 2019

The effect of atorvastatin on serum lipids, lipoproteins and NMR spectroscopy defined lipoprotein subclasses in type 2 diabetic patients with ischaemic heart disease

scientific article

The effect of atorvastatin therapy on tumour necrosis factor-α and vascular adhesion molecules in patients with type 2 diabetes mellitus with no prior history of coronary heart disease

scientific article published in November 2011

The effect of deprivation and HbA1c on admission to hospital for diabetic ketoacidosis in type 1 diabetes.

scientific article

The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished data from major randomized trials

scientific article

The effect of type 1 diabetes mellitus on the gender difference in coronary artery calcification

scientific article published in December 2000

The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome

scientific article published in May 2002

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1.

scientific article published on 26 April 2013

The response to sulpiride in social anxiety disorder: D2 receptor function

scientific article

The safety and tolerability of atorvastatin 10 mg in the Collaborative Atorvastatin Diabetes Study (CARDS).

scientific article

Time trends in deaths before age 50 years in people with type 1 diabetes: a nationwide analysis from Scotland 2004-2017

scientific article published on 26 May 2020

Total soluble and endogenous secretory receptor for advanced glycation end products as predictive biomarkers of coronary heart disease risk in patients with type 2 diabetes: an analysis from the CARDS trial

scientific article

Treatment of lipid disorders in patients with diabetes

scientific article published in February 2006

Trends in hypertension management in Type I diabetes across Europe, 1989/1990 - 1997/1999.

scientific article published on 7 September 2002

Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013.

scientific article published on 28 July 2016

Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001-2007.

scientific article

Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study

scientific article published on 30 July 2018

Use of personalised risk-based screening schedules to optimise workload and sojourn time in screening programmes for diabetic retinopathy: A retrospective cohort study

scientific article published on 17 October 2019

Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials

scientific article published on August 2014

Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease.

scientific article

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