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List of works by Lei Wang

A New Functional Suppressor tRNA/Aminoacyl−tRNA Synthetase Pair for the in Vivo Incorporation of Unnatural Amino Acids into Proteins

scientific article (publication date: May 2000)

A fluorescent reporter of the phosphorylation status of the substrate protein STAT3.

scientific article published on 29 July 2011

A general approach for the generation of orthogonal tRNAs.

scientific article

A method for the generation of glycoprotein mimetics

scientific article

A new strategy for the site-specific modification of proteins in vivo.

scientific article published on June 2003

A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time

scientific article

Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli

scientific article (publication date: 6 March 2002)

Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.

scientific article published on 04 August 2013

Addition of a photocrosslinking amino acid to the genetic code of Escherichiacoli

scientific article

Addition of the keto functional group to the genetic code of Escherichia coli.

scientific article

Amersham Prize winner. Expanding the genetic code

scientific article published in October 2003

An efficient system for the evolution of aminoacyl-tRNA synthetase specificity

scientific article published on 16 September 2002

An investigation on the Mutual-Phobicity between Fluorocarbon and Hydrocarbon Surfactants by Atomic Force Microscopy

scientific article published on 01 January 1997

Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins

scientific article published on 05 September 2018

Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine

scientific article

Cysteine Sulfoxidation Increases the Photostability of Red Fluorescent Proteins

scientific article

Developing High Resolution Electrical Probing System Based on Atomic Force Microscopy

Development of background-free tame fluorescent probes for intracellular live cell imaging

scientific article

Editorial overview: Chemistry for biopolymers to investigate and even move beyond nature

scientific article published on 14 October 2016

Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid

scientific article

Engineering the Genetic Code in Cells and Animals: Biological Considerations and Impacts.

scientific article published on 6 October 2017

Evolution of new nonantibody proteins via iterative somatic hypermutation.

scholarly article

Evolving proteins in mammalian cells using somatic hypermutation

scientific article published on January 2006

Expanding the Genetic Code

scientific article published on 01 December 2004

Expanding the genetic code

scientific article (publication date: 2006)

Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs

scientific article

Expanding the genetic code of Escherichia coli

scientific article (publication date: 20 April 2001)

Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings

scientific article

Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions

scientific article published on 15 January 2013

Fabrication of Gold Nanostructures on Graphite Using Atomic Force Microscope

Generation of a bacterium with a 21 amino acid genetic code

scientific article published in January 2003

Genetic incorporation of unnatural amino acids into proteins in yeast

scientific article published on January 2012

Genetically Encoding Fluorosulfate-l-tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo.

scientific article published on 30 March 2018

Genetically Encoding Photocaged Quinone Methide to Multitarget Protein Residues Covalently in Vivo

scientific article published on 04 June 2019

Genetically Encoding Quinoline Reverses Chromophore Charge and Enables Fluorescent Protein Brightening in Acidic Vesicles

scientific article published on 22 August 2018

Genetically Encoding a Lipidated Amino Acid for Extension of Protein Half-Life in vivo

scientific article published on 21 December 2018

Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins

scientific article published on 03 May 2019

Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR

scientific journal article

Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors

scientific article published on 15 July 2014

Genetically encoding new bioreactivity

scientific article

Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cells

scientific article

Heritable expansion of the genetic code in mouse and zebrafish

scientific article

Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator

scientific article published on October 2009

Imprints of the genetic code in the ribosome

scientific article (publication date: 4 May 2010)

Improving orthogonal tRNA-synthetase recognition for efficient unnatural amino acid incorporation and application in mammalian cells

scientific article

In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light

scientific article published on 24 August 2015

In vivo expression of a light-activatable potassium channel using unnatural amino acids

scientific article

Manipulating proteins for neuroscience

scientific article published on 7 September 2006

New methods enabling efficient incorporation of unnatural amino acids in yeast

scientific article published on 22 April 2008

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

scientific article published on 28 March 2016

Optocontrol of glutamate receptor activity by single side-chain photoisomerization

scientific article published on 23 May 2017

Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison

scientific article published on 12 July 2011

Photocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes

scientific article published on 08 November 2019

Proximity-enabled bioreactivity to generate covalent peptide inhibitors of p53-Mdm4.

scientific article published on 21 March 2016

Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids.

scientific article published on 21 January 2014

Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry

article published in the Proceedings of the National Academy of Sciences of the United States of America

Response and adaptation of Escherichia coli to suppression of the amber stop codon

scientific article

Selective labeling of proteins with chemical probes in living cells

scientific article published on June 2008

Site-Specific Incorporation of Selenocysteine Using an Expanded Genetic Code and Palladium-Mediated Chemical Deprotection

scientific article published in 2018

Site-specific incorporation of phosphotyrosine using an expanded genetic code

scientific article published on 12 June 2017

Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.

scientific article published on 21 December 2017

Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids

scientific article

Synthesis of Chiral Spin-Labeled Amino Acids

scientific article published on 10 December 2019

The selective incorporation of alkenes into proteins in Escherichia coli

scientific article published in August 2002

The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination

scientific article published on 19 September 2004

Unique interactions between the chromophore and glutamate 16 lead to far-red emission in a red fluorescent protein

scientific article published on February 2009

Unnatural amino acid mutagenesis of green fluorescent protein

scientific article

Using Protein-Confined Proximity To Determine Chemical Reactivity

scientific article published on 31 October 2016

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