List of works by Thomas Laurell

2DDB - a bioinformatics solution for analysis of quantitative proteomics data

scientific article

A Highly Sensitive Porous Silicon (P-Si)-Based Human Kallikrein 2 (hK2) Immunoassay Platform toward Accurate Diagnosis of Prostate Cancer

scientific article published on 22 May 2015

A Sol-gel Integrated Dual-readout Microarray Platform for Quantification and Identification of Prostate-specific Antigen

scientific article published in January 2018

A continuous glucose monitoring system based on microdialysis

scientific article published on 01 September 1992

A critical evaluation of inflammatory markers in Huntington's Disease plasma.

scientific article published in January 2013

A method for the design and study of enzyme microstructures formed by means of a flow-through microdispenser

scientific article published in September 2001

A miniaturised electrochemical affinity assay based on a wall-free sample droplet and micro-dispensing of the redox-labelled binding partner

scientific article published in December 2001

A new look at drugs targeting malignant melanoma--an application for mass spectrometry imaging

scientific article

A porous silicon immunoassay platform for fluorometric determination of α-synuclein in human cerebrospinal fluid

A protein deep sequencing evaluation of metastatic melanoma tissues

scientific article

A simple one-step assay platform based on fluorescence quenching of macroporous silicon

scientific article

A single inlet two-stage acoustophoresis chip enabling tumor cell enrichment from white blood cells

scientific article

A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing

scientific article published on 29 May 2019

Acoustic Enrichment of Extracellular Vesicles from Biological Fluids

scientific article published on 11 June 2018

Acoustic actuated fluorescence activated sorting of microparticles.

scientific article published on 25 April 2014

Acoustic control of suspended particles in micro fluidic chips.

scientific article published on 9 February 2004

Acoustic differential extraction for forensic analysis of sexual assault evidence

scientific article

Acoustic impedance matched buffers enable separation of bacteria from blood cells at high cell concentrations.

scientific article

Acoustic microfluidic chip technology to facilitate automation of phage display selection.

scientific article

Acoustic radiation forces at liquid interfaces impact the performance of acoustophoresis.

scientific article published in September 2014

Acoustic radiation- and streaming-induced microparticle velocities determined by microparticle image velocimetry in an ultrasound symmetry plane

scientific article published on 13 November 2012

Acoustic resonances in straight micro channels: beyond the 1D-approximation.

scientific article published on 16 May 2008

Acoustic trapping as a generic non-contact incubation site for multiplex bead-based assays

scientific article

Acoustic trapping for bacteria identification in positive blood cultures with MALDI-TOF MS.

scientific article

Acoustic whole blood plasmapheresis chip for prostate specific antigen microarray diagnostics.

scientific article published in August 2009

Acousto-microfluidics for screening of ssDNA aptamer.

scientific article

Acoustofluidic harvesting of microalgae on a single chip.

scientific article published on May 2016

Acoustofluidic hematocrit determination

scientific article published on 22 November 2017

Acoustofluidic, label-free separation and simultaneous concentration of rare tumor cells from white blood cells.

scientific article published on 26 August 2015

Acoustofluidics 11: Affinity specific extraction and sample decomplexing using continuous flow acoustophoresis.

scientific article published on 2 April 2012

Acoustofluidics 5: Building microfluidic acoustic resonators

scientific article published on 16 January 2012

Acoustofluidics 8: applications of acoustophoresis in continuous flow microsystems.

scientific article published on 24 February 2012

Acoustophoresis enables the label-free separation of functionally different subsets of cultured bone marrow stromal cells

scientific article published on 15 June 2020

Acoustophoresis in wet-etched glass chips

scientific article published on 20 May 2008

Affinity-Bead-Mediated Enrichment of CD8+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Acoustophoresis

scientific article published on 09 June 2016

Analysis of alpha-synuclein in malignant melanoma - development of a SRM quantification assay

scientific article

Analysis of regulatory phosphorylation sites in ZAP-70 by capillary high-performance liquid chromatography coupled to electrospray ionization or matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article

Aptamer microarray mediated capture and mass spectrometry identification of biomarker in serum samples

scientific article published on 24 September 2010

Aptamer/ISET-MS: a new affinity-based MALDI technique for improved detection of biomarkers

scientific article

Automated and temperature-controlled micro-PIV measurements enabling long-term-stable microchannel acoustophoresis characterization

scientific article published on 12 October 2011

Autonomous protein sample processing on-chip using solid-phase microextraction, capillary force pumping, and microdispensing

scientific article

Bilberry Supplementation after Myocardial Infarction Decreases Microvesicles in Blood and Affects Endothelial Vesiculation

scientific article published on 26 August 2020

Biocompatibility of surfaces for antibody microarrays: design of macroporous silicon substrates

scientific article published on 01 June 2005

Bioelectrochemical studies of azurin and laccase confined in three-dimensional chips based on gold-modified nano-/microstructured silicon

scientific article published on 19 September 2009

Biogrid--a microfluidic device for large-scale enzyme-free dissociation of stem cell aggregates.

scientific article published on 17 August 2011

Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples

scientific article

Capillary liquid chromatography interfaced to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using an on-line coupled piezoelectric flow-through microdispenser

scientific article

Carrier medium exchange through ultrasonic particle switching in microfluidic channels

scientific article published in March 2005

Chip integrated strategies for acoustic separation and manipulation of cells and particles

scientific article published on 7 December 2006

Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium.

scientific article

Classification of motor commands using a modified self-organising feature map.

scientific article published on 19 February 2005

Clinical Proteomics; protein expression research within disease--A challenging task

scientific article published on 24 March 2010

Clinical-Scale Cell-Surface-Marker Independent Acoustic Microfluidic Enrichment of Tumor Cells from Blood

scientific article published on 31 October 2017

Comparative Proteomic Analysis of Extracellular Vesicles Isolated by Acoustic Trapping or Differential Centrifugation.

scientific article

Concurrent isolation of lymphocytes and granulocytes using prefocused free flow acoustophoresis

scientific article

Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy.

scientific article published on 13 October 2006

Continuous flow microfluidic separation and processing of rare cells and bioparticles found in blood - A review

scientific article published on 20 February 2017

Continuous flow two-dimensional acoustic orientation of nonspherical cells.

scientific article published on 6 June 2014

Continuous separation of cells and particles in microfluidic systems

scientific article published on 04 February 2010

Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces

scientific article published on 17 September 2004

Correction: Acoustic actuated fluorescence activated sorting of microparticles

scientific article published on 3 November 2015

Correction: A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing

scientific article published on 24 October 2019

Correlation of histopathologic characteristics to protein expression and function in malignant melanoma

scientific article

Decomplexing biofluids using microchip based acoustophoresis.

scientific article published in December 2008

Determination of diffusion coefficients of electroactive species in time-of-flight experiments using a microdispenser and microelectrodes

scientific article published on 01 June 2001

Development of biosensors based on hexacyanoferrates

scientific article published on 01 August 2000

Development of silicon microstructures and thin-film MALDI target plates for automated proteomics sample identifications

scientific article

Developments in biobanking workflow standardization providing sample integrity and stability

scientific article

Developments toward a microfluidic system for long-term monitoring of dynamic cellular events in immobilized human cells

scientific article published on August 2004

Differential impedance spectra analysis reveals optimal actuation frequency in bulk mode acoustophoresis

scientific article published on 13 December 2019

Disposable polymeric high-density nanovial arrays for matrix assisted laser desorption/ionization-time of flight-mass spectrometry: II. Biological applications

scientific article

Downsizing proteolytic digestion and analysis using dispenser-aided sample handling and nanovial matrix-assisted laser/desorption ionization-target arrays

scientific article

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging.

scientific article

ENSAM: Europium Nanoparticles for Signal enhancement of Antibody Microarrays on nanoporous silicon.

scientific article published on 8 February 2008

Editorial--microtechnology developments for proteomic research

scientific article published on 01 April 2002

Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation

scientific article published on 01 October 2018

Efficient purification of CD4+ lymphocytes from peripheral blood progenitor cell products using affinity bead acoustophoresis

scientific article published on 22 July 2014

Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform

scientific article

Emerging clinical applications of microchip-based acoustophoresis.

scientific article published on 22 September 2011

Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry

scientific article

Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability

scientific article published on 27 February 2013

Evaluation of glucose biosensors based on Prussian Blue and lyophilised, crystalline and cross-linked glucose oxidases (CLEC(R)).

scientific article published in June 2001

Experimental models to study drug distributions in tissue using MALDI mass spectrometry imaging.

scientific article

Feasibility study on measuring selected proteins in malignant melanoma tissue by SRM quantification.

scientific article published on 17 February 2014

Filter Plate-Based Screening of MIP SPE Materials for Capture of the Biomarker Pro-Gastrin-Releasing Peptide

scientific article published on 31 January 2017

Flow-through microdispenser for interfacing micro-HPLC to Raman and mid-IR spectroscopic detection

scientific article published in July 2005

Focusing of sub-micrometer particles and bacteria enabled by two-dimensional acoustophoresis.

scientific article published on 4 June 2014

Forthcoming Lab on a Chip tutorial series on acoustofluidics: acoustofluidics-exploiting ultrasonic standing wave forces and acoustic streaming in microfluidic systems for cell and particle manipulation.

scientific article published on 26 September 2011

Fourier transform infrared detection in miniaturized total analysis systems for sucrose analysis

scientific article published on 01 August 1997

Free flow acoustophoresis: microfluidic-based mode of particle and cell separation

scientific article published on 15 June 2007

Gradient acoustic focusing of sub-micron particles for separation of bacteria from blood lysate

scientific article published on 28 February 2020

Harmonic microchip acoustophoresis: a route to online raw milk sample precondition in protein and lipid content quality control

scientific article published on 01 August 2009

High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry

scientific article

Highly efficient single cell arraying by integrating acoustophoretic cell pre-concentration and dielectrophoretic cell trapping

scientific article published on 6 October 2015

Homogeneous sample preparation for automated high throughput analysis with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry

scientific article

Identification of a novel proteoform of prostate specific antigen (SNP-L132I) in clinical samples by multiple reaction monitoring

scientific article

Identification of novel candidate protein biomarkers for the post-polio syndrome - implications for diagnosis, neurodegeneration and neuroinflammation

scientific article

Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms

scientific article

Implementation of a protein profiling platform developed as an academic-pharmaceutical industry collaborative effort

scientific article

Improved chip design for integrated solid-phase microextraction in on-line proteomic sample preparation

scientific article

Improved performance in silicon enzyme microreactors obtained by homogeneous porous silicon carrier matrix

scientific article published in February 2002

Improved porous silicon microarray based prostate specific antigen immunoassay by optimized surface density of the capture antibody

scientific article

Inflammatory markers in Huntington's disease plasma—A robust nanoLC–MRM-MS assay development

Integrated Acoustic Separation, Enrichment, and Microchip Polymerase Chain Reaction Detection of Bacteria from Blood for Rapid Sepsis Diagnostics.

scientific article

Integrated acoustic immunoaffinity-capture (IAI) platform for detection of PSA from whole blood samples

scientific article

Integrated microanalytical technology enabling rapid and automated protein identification

scientific article

Integrated protein microchip assay with dual fluorescent- and MALDI read-out

scientific article

Integrated selective enrichment target--a microtechnology platform for matrix-assisted laser desorption/ionization-mass spectrometry applied on protein biomarkers in prostate diseases

scientific article

Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects

scientific article published on 01 January 2005

Isolation of a Low Number of Sperm Cells from Female DNA in a Glass-PDMS-Glass Microchip via Bead-Assisted Acoustic Differential Extraction

scientific article published on 17 January 2019

Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples

scientific article

Lab on a chip: Scandinavia.

scientific article published in November 2012

Label-free concentration of viable neurons, hESCs and cancer cells by means of acoustophoresis.

scientific article

Label-free neuroblastoma cell separation from hematopoietic progenitor cell products using acoustophoresis - towards cell processing of complex biological samples.

scientific article published on 19 June 2019

Label-free separation of leukocyte subpopulations using high throughput multiplex acoustophoresis

scientific article published on 01 April 2019

Label-free single-cell separation and imaging of cancer cells using an integrated microfluidic system.

scientific article

Label-free somatic cell cytometry in raw milk using acoustophoresis

scientific article published on 18 October 2012

MALDI-target integrated platform for affinity-captured protein digestion

scientific article

MRM assay for quantitation of complement components in human blood plasma — a feasibility study on multiple sclerosis

article published in 2011

Macro-/nanoporous silicon as a support for high-performance protein microarrays

scientific article published in December 2003

Mass-tag enhanced immuno-laser desorption/ionization mass spectrometry for sensitive detection of intact protein antigens.

scientific article published on 30 April 2015

Measuring the local pressure amplitude in microchannel acoustophoresis

scientific article published on 27 January 2010

Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells

scientific article

Microchip immobilized enzyme reactors for hydrolysis of methyl cellulose

scientific article

Microfluidic biosensing systems. Part I. Development and optimisation of enzymatic chemiluminescent micro-biosensors based on silicon microchips

scientific article published on 14 September 2004

Microfluidic biosensing systems. Part II. Monitoring the dynamic production of glucose and ethanol from microchip-immobilised yeast cells using enzymatic chemiluminescent micro-biosensors.

scientific article published on 14 September 2004

Microfluidic components for protein characterization

scientific article

Microfluidic enzyme immunoassay using silicon microchip with immobilized antibodies and chemiluminescence detection

scientific article

Microfluidic enzyme immunosensors with immobilised protein A and G using chemiluminescence detection

scientific article published in October 2003

Microfluidic, label-free enrichment of prostate cancer cells in blood based on acoustophoresis

scientific article

Microparticle Acoustophoresis in Aluminum-Based Acoustofluidic Devices with PDMS Covers

scientific article published on 11 March 2020

Miniaturisation is mandatory unravelling the human proteome

scientific article

Miniaturization in analytical and bioanalytical chemistry

scientific article published on 03 March 2004

Miniaturized and automated high-throughput verification of proteins in the ISET platform with MALDI MS.

scientific article

Miniaturized solid-phase extraction and sample preparation for MALDI MS using a microfabricated integrated selective enrichment target

scientific article

Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry

scientific article

Molecularly imprinted polymers synthesized via template immobilization on fumed silica nanoparticles for the enrichment of phosphopeptides.

scientific article published on 12 October 2017

Monitoring of enzymatic hydrolysis of starch by microdialysis sampling coupled on-line to anion exchange chromatography and integrated pulsed electrochemical detection using post-column switching

scientific article published in December 1997

Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels

scientific article

Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers

article

Multiplexed MALDI-MS arrays for screening of MIP solid phase extraction materials.

scientific article published on 30 October 2015

Myoelectric control of a computer animated hand: a new concept based on the combined use of a tree-structured artificial neural network and a data glove

scientific article

New directions of miniaturization within the biomarker research area

scientific article

New directions of miniaturization within the proteomics research area

scientific article

Non-contact acoustic capture of microparticles from small plasma volumes

scientific article published in June 2015

Non-contact acoustic cell trapping in disposable glass capillaries.

scientific article published on 30 June 2010

Noncovalent antibody immobilization on porous silicon combined with miniaturized solid-phase extraction (SPE) for array based immunoMALDI assays

scientific article

Noninvasive acoustic cell trapping in a microfluidic perfusion system for online bioassays.

scientific article published on 22 February 2007

On-chip microextraction for proteomic sample preparation of in-gel digests

scientific article

On-chip microfluidic systems for determination of L-glutamate based on enzymatic recycling of substrate

scientific article published on 16 March 2009

On-line coupling of microdialysis sampling with liquid chromatography for the determination of peptide and non-peptide leukotrienes

scientific article published on October 1998

On-line monitoring of airborne chemistry in levitated nanodroplets: in situ synthesis and application of SERS-active Ag-Sols for trace analysis by FT-Raman spectroscopy

scientific article published in May 2003

Optimal membrane choice for microdialysis sampling of oligosaccharides

scientific article published in May 1998

Optimizing nanovial outlet designs for improved solid-phase extraction in the integrated selective enrichment target--ISET.

scientific article

Particle separation using ultrasound can be used with human shed mediastinal blood

scientific article

Particle separation using ultrasound can radically reduce embolic load to brain after cardiac surgery

scientific article published in November 2004

Perforated silicon nerve chips with doped registration electrodes: in vitro performance and in vivo operation.

scientific article published in September 1999

Picodroplet-deposition of enzymes on functionalized self-assembled monolayers as a basis for miniaturized multi-sensor structures

scientific article published in December 2001

Picoliter sample preparation in MALDI-TOF MS using a micromachined silicon flow-through dispenser

scientific article published on November 1998

Polymeric integrated selective enrichment target (ISET) for solid-phase-based sample preparation in MALDI-TOF MS.

scientific article

Porous silicon antibody microarrays for quantitative analysis: measurement of free and total PSA in clinical plasma samples

scientific article

Porous silicon protein microarray technology and ultra-/superhydrophobic states for improved bioanalytical readout

scientific article

Porous silicon surfaces: a candidate substrate for reverse protein arrays in cancer biomarker detection

scientific article published on December 2007

Protein chips based on recombinant antibody fragments: a highly sensitive approach as detected by mass spectrometry

scientific article

Protein identification platform utilizing micro dispensing technology interfaced to matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article published in July 2000

Proteomic profiling of extracellular vesicles reveals additional diagnostic biomarkers for myocardial infarction compared to plasma alone

scientific article published on 20 June 2019

Quantification of total apolipoprotein E and its specific isoforms in cerebrospinal fluid and blood in Alzheimer’s disease and other neurodegenerative diseases

Rapid and effective enrichment of mononuclear cells from blood using acoustophoresis.

scientific article published on 7 December 2017

Rat sciatic nerve regeneration through a micromachined silicon chip.

scientific article published in January 1997

Ready-made matrix-assisted laser desorption/ionization target plates coated with thin matrix layer for automated sample deposition in high-density array format

scientific article

Reducing WBC background in cancer cell separation products by negative acoustic contrast particle immuno-acoustophoresis

scientific article published on 5 December 2017

Regeneration of central nervous axons through micromachined silicone chips

Reverse-phase versus sandwich antibody microarray, technical comparison from a clinical perspective.

scientific article published on 3 July 2007

Review of cell and particle trapping in microfluidic systems

scientific article published on 14 July 2009

Sample enrichment in a single levitated droplet for capillary electrophoresis

scientific article published on 01 August 1998

Screening of nucleation conditions using levitated drops for protein crystallization

scientific article published in April 2003

Seed particle-enabled acoustic trapping of bacteria and nanoparticles in continuous flow systems.

scientific article published in November 2012

Separation of lipids from blood utilizing ultrasonic standing waves in microfluidic channels

scientific article published on 18 August 2004

Signal amplification using "spot-on-a-chip" technology for the identification of proteins via MALDI-TOF MS.

scientific article

Silicon microstructures for high-speed and high-sensitivity protein identifications

scientific article

Sol-gel derived nanoporous compositions for entrapping small molecules and their outlook toward aptamer screening.

scientific article published on 27 February 2012

Solid-phase extraction of the alcohol abuse biomarker phosphatidylethanol using newly synthesized polymeric sorbent materials containing quaternary heterocyclic groups

scientific article published on 25 August 2017

Standardization and utilization of biobank resources in clinical protein science with examples of emerging applications

scientific article

Synthesis of NaYF 4 : Yb3+/Er3+upconverting nanocrystals in a capillary-based continuous microfluidic reaction system

scientific article published on 10 February 2011

Temperature and trapping characterization of an acoustic trap with miniaturized integrated transducers--towards in-trap temperature regulation

scientific article published on 8 February 2013

The geometric design of micromachined silicon sieve electrodes influences functional nerve regeneration

scientific article published on 01 May 2001

Thin-layer immunoaffinity chromatography with bar code quantitation of C-reactive protein

scientific article published in September 1995

Thousand-fold volumetric concentration of live cells with a recirculating acoustofluidic device.

scientific article published on 30 July 2015

Tissue reactions evoked by porous and plane surfaces made out of silicon and titanium

scientific article

Trapping of microparticles in the near field of an ultrasonic transducer.

scientific article published on 13 December 2004

Two-dimensional acoustic particle focusing enables sheathless chip Coulter counter with planar electrode configuration

scientific article

Two-hundredfold volume concentration of dilute cell and particle suspensions using chip integrated multistage acoustophoresis

scientific article published on November 2012

Ultrasonic agitation in microchannels

scientific article published on 20 December 2003

Ultrasound Characterization of Microbead and Cell Suspensions by Speed of Sound Measurements of Neutrally Buoyant Samples

scientific article

Ultrasound-induced acoustophoretic motion of microparticles in three dimensions.

scientific article published on 8 August 2013