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List of works by Douglas F. Nixon

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males

scientific article

A decreased frequency of regulatory T cells in patients with common variable immunodeficiency

scientific article

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

scientific article

A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis

scientific article published on 01 March 2001

A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals

scientific article published in May 1999

A simple and rapid magnetic bead separation technique for the isolation of tetramer-positive virus-specific CD8 T cells

scientific article published in April 2001

Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children

scientific article

Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells

scientific article published in January 2002

An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants

scientific article published in September 2001

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers

scientific article

Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol ⬇️

scientific article

Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children

scientific article

Associations between antibodies to a panel of Plasmodium falciparum specific antigens and response to sub-optimal antimalarial therapy in Kampala, Uganda

scientific article

Boosting of SIV-specific T cell responses in rhesus macaques that resist repeated intravaginal challenge with SIVmac251.

scientific article published in September 2002

Brain Ia antigens have a bone marrow origin

scientific article published in January 1983

CD4+CD25+ regulatory T cells in HIV infection.

scientific article

CD56negCD16⁺ NK cells are activated mature NK cells with impaired effector function during HIV-1 infection

scientific article published on 18 December 2013

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

scientific article

CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis

scientific article

CD8 T cell effector maturation in HIV-1-infected children

scientific article published on 6 January 2006

CTL induction using synthetic peptides delivered in emulsions— critical role of the formulation procedure

scientific article published on 01 November 1997

Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection

scientific article published in December 2003

Changes in Frequency of HIV‐1–Specific Cytotoxic T Cell Precursors and Circulating Effectors after Combination Antiretroviral Therapy in Children

scientific article published in August 1999

Characterization of HIV-1-Specific Cytotoxic T Lymphocytes Expressing the Mucosal Lymphocyte Integrin CD103 in Rectal and Duodenal Lymphoid Tissue of HIV-1-Infected Subjects

article

Comments on "coinfection of SARS-CoV-2 and HIV in a patient in Wuhan city, China"

scientific article published on 03 April 2020

Comparison of adjuvant formulations for cytotoxic T cell induction using synthetic peptides

scientific article published in April 1996

Comparison of restimulation methods to elicit SIV specific cytotoxic T-lymphocytes (CTL) in vitro: Staphylococcal enterotoxin B (SEB) provides a novel method for the quantification of SIV specific CTL precursors.

scientific article published on March 1999

Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells

scientific article published in December 2003

Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease

scientific article published on 21 January 2014

Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection

scientific article published on 27 February 2008

Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure

scientific article published on 17 January 2002

Cross-sectional dating of novel haplotypes of HERV-K 113 and HERV-K 115 indicate these proviruses originated in Africa before Homo sapiens

scientific article

Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells

scientific article

Cytotoxic T cell induction with ratchet peptide libraries.

scientific article published on December 1996

Decay kinetics of HIV-1 specific T cell responses in vertically HIV-1 exposed seronegative infants

scientific article published in January 2011

Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women.

scientific article published in July 2002

Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma

scientific article

Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7

scientific article

Dicer-2 Regulates Resistance and Maintains Homeostasis against Zika Virus Infection in

scientific article published on 10 October 2018

Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection

scientific article published on 13 December 2012

Differentiation and functional regulation of human fetal NK cells

scientific article published on 15 August 2013

Diminished humoral responses against and reduced gene expression levels of human endogenous retrovirus-K (HERV-K) in psoriasis

scientific article

Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19.

scientific article published on January 2001

Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.

scientific article

Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Valpha24 NKT cell compartment.

scientific article published in March 2003

Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene

scientific article

Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo

scientific article

ELISPOT cell rescue

scientific article published in May 2004

Effects of cellular activation on anti-HIV-1 restriction factor expression profile in primary cells

scientific article published on 21 August 2013

Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus

scientific article

Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions

scientific article published in November 2002

Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay.

scientific article

Enhancement of human immunodeficiency virus type 1-specific CD4 and CD8 T cell responses in chronically infected persons after temporary treatment interruption

scientific article published on 17 August 2000

Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice

scientific article published on 22 April 2014

Epidemiological Evidence for Association between Higher Influenza Vaccine Uptake in the Elderly and Lower COVID-19 Deaths in Italy

scientific article published on 04 June 2020

Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus

scientific article

Evaluation of a Lipopeptide Immunogen as a Therapeutic in HIV Type 1-Seropositive Individuals

article

Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications.

scientific article

Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2

scientific article published on 20 December 2005

Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment

scientific article published on 12 August 2004

Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity

scientific article published on December 2011

Expansion of a unique CD57⁺NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

scientific article

Expression profile of host restriction factors in HIV-1 elite controllers

scientific article published on 16 October 2013

Extreme immunotherapy: emergency immunology to defeat pandemics

scientific article published on 16 September 2021

FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection

scientific article

Factors associated with attitudes towards HIV cure research among transgender women and travestis: a cross-sectional survey in São Paulo, Brazil

scientific article published on 11 November 2020

Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4.

scientific article published on 05 October 2009

HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates.

scientific article

HIV-1 Vpu interference with innate cell-mediated immune mechanisms

scientific article

HIV-1 drug resistance prevalence, drug susceptibility and variant characterization in the Jacobi Medical Center paediatric cohort, Bronx, NY, USA.

scientific article published on 25 September 2013

HIV-1-Specific CD4+ T Cell Responses in Chronically HIV-1 Infected Blippers on Antiretroviral Therapy in Relation to Viral Replication Following Treatment Interruption

article

HIV-1-specific T Cell-dependent natural killer (NK) cell activation: major contribution by NK cells to interferon-gamma production in response to HIV-1 antigens

scientific article

HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts

scientific article

HLA-C downregulation by HIV-1 adapts to host HLA genotype

article

HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications

scientific article

Herpes simplex virus and HIV-1: deciphering viral synergy

scientific article published in February 2009

Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave

scientific article published on 11 January 2022

High Frequency of Cytomegalovirus‐Specific Cytotoxic T‐Effector Cells in HLA‐A*0201–Positive Subjects during Multiple Viral Coinfections

article

Higher frequency of HIV-1-specific T cell immune responses in African American children vertically infected with HIV-1.

scientific article

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

scientific article published on March 2004

Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival

scientific article published on 28 August 2020

Human Endogenous Retrovirus Expression Is Inversely Associated with Chronic Immune Activation in HIV-1 Infection ⬇️

scientific article published on August 7, 2012

Human endogenous retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods

scientific article published on 10 January 2013

Human endogenous retrovirus K(HML-2) Gag- and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening.

scientific article published on 28 December 2011

Human endogenous retrovirus K106 (HERV-K106) was infectious after the emergence of anatomically modern humans

scientific article

Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set point

scientific article published on 21 March 2007

Human immunodeficiency virus type 1- and cytomegalovirus-specific cytotoxic T lymphocytes can persist at high frequency for prolonged periods in the absence of circulating peripheral CD4(+) T cells.

scientific article published on January 2000

IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.

scientific article

Identification of human endogenous retrovirus-specific T cell responses in vertically HIV-1-infected subjects.

scientific article

Identification of subdominant cytotoxic T lymphocyte epitopes encoded by autologous HIV type 1 sequences, using dendritic cell stimulation and computer-driven algorithm.

scientific article

Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruption

scientific article

Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2.

scientific article

Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.

scientific article

Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.

scientific article

Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia

scientific article published in April 2004

Increased adhesion molecule and chemokine receptor expression on CD8+ T cells trafficking to cerebrospinal fluid in HIV-1 infection.

scientific article published on 24 May 2004

Increased expression of intrinsic antiviral genes in HLA-B*57-positive individuals

scientific article published on 08 August 2013

Increased number and function of natural killer cells in human immunodeficiency virus 1-positive subjects co-infected with herpes simplex virus 2.

scientific article

Individuals with pulmonary tuberculosis have lower levels of circulating CD1d-restricted NKT cells

scientific article published on 20 March 2007

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

scientific article published on 29 February 2024

Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection

scientific article

Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120

scientific article

Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

scientific article published on May 2009

Invariant natural killer T (iNKT) cell exhaustion in sarcoidosis.

scientific article published on 25 June 2013

Invariant natural killer T cells developing in the human fetus accumulate and mature in the small intestine.

scientific article published on 19 March 2014

Inversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion

scientific article published on July 2016

Isolation of Cytomegalovirus-Specific Cytotoxic T-Lymphocytes from Gut-Associated Lymphoid Tissue (GALT) of HIV Type 1-Infected Subjects

article

LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells.

scientific article published on 02 October 2013

Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers

scientific article published on 03 May 2021

Longitudinal and cross-sectional analysis of cytotoxic T lymphocyte responses and their relationship to vertical human immunodeficiency virus transmission. ARIEL Project Investigators

scientific article published in November 1998

Lower cytokine secretion ex vivo by natural killer T cells in HIV-infected individuals is associated with higher CD161 expression

scientific article

Lower numbers of circulating Natural Killer T (NK T) cells in individuals with human T lymphotropic virus type 1 (HTLV-1) associated neurological disease.

scientific article published on 2 September 2009

Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients.

scientific article published in May 2012

Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero

scientific article published on December 2008

Molecular tracking of an Human Immunodeficiency Virus nef specific cytotoxic T-cell clone shows persistence of clone-specific T-cell receptor DNA but not mRNA following early combination antiretroviral therapy

scientific article published in March 1999

Montelukast drug activity and potential against SARS-CoV-2

scientific article published on 13 July 2020

NK cells and CD1d-restricted NKT cells respond in different ways with divergent kinetics to IL-2 treatment in primary HIV-1 infection

scientific article

Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach

scientific article

Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms.

scientific article published in May 2008

Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition

scientific article

Optimization of methods to assess human mucosal T-cell responses to HIV infection.

scientific article published in August 2003

P16-10. IL-2 therapy mediates expansion of Treg cells, maintains IL-17 expressing CD4+ T-cells and selectively suppresses HIV specific T-cell responses

article

P16-30. Induction of Tim-3 expression by the common gamma-chain cytokines IL-2, IL-7, IL-15 and IL-21.

scientific article

Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(+) T-cell responses which can be defined to the epitope level

scientific article published on 24 September 2008

Presence of human immunodeficiency virus-1-specific CD4 and CD8 cellular immune responses in children with full or partial virus suppression

scientific article published on 4 September 2003

Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility

scientific article

Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease

scientific article

Psoriasis risk SNPs and their association with HIV-1 control

scientific article

Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface

article

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

scientific article published in Science

R5 human immunodeficiency virus type 1 (HIV-1) replicates more efficiently in primary CD4+ T-cell cultures than X4 HIV-1.

scientific article published on September 2004

Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes

scientific article

Rapid quantification of SIV-specific CD8 T cell responses with recombinant vaccinia virus ELISPOT or cytokine flow cytometry.

scientific article published in November 2000

Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3.

scientific article published in July 2004

Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection

scientific article published in January 2002

Restriction of HIV-1 infection in sickle cell trait

scientific article published in 2021

Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection

scientific article published in October 2000

Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection

scientific article

Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape ⬇️

scientific article published on 21 February 2007

Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection

scientific article published on 23 January 2006

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine.

scientific article published in January 2000

Skewed distribution of circulating activated natural killer T (NKT) cells in patients with common variable immunodeficiency disorders (CVID)

scientific article

Skewed distribution of natural killer cells in psoriasis skin lesions.

scientific article published on January 2013

Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal

scientific article

Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection

scientific article

Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy

scientific article published on 5 April 2000

Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection.

scientific article

Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity

scientific article

T cell immunity in acute HIV-1 infection.

scientific article published on October 2010

T cell responses to human endogenous retroviruses in HIV-1 infection

scientific article

T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques.

scientific article published on 27 March 2013

T lymphocyte responses against human parvovirus B19: small virus, big response

scientific article published in June 2002

TGF-β Sustains Tumor Progression through Biochemical and Mechanical Signal Transduction.

scientific article published on 14 June 2018

Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion

scientific article published on 8 January 2013

Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression

scientific article published on 30 September 2019

Telomere length and human hippocampal neurogenesis

scientific article published on 13 September 2020

Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques

scientific article published on 21 December 2006

The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool

scientific article published on 15 November 2018

The behavioral, cellular and immune mediators of HIV-1 acquisition: New insights from population genetics

scientific article published on 24 February 2020

The calm mouse: an animal model of stress reduction

scientific article

The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses

scientific article published in March 1999

The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article published on 29 July 2008

The impact of early initiation of highly active antiretroviral therapy on the human immunodeficiency virus type 1-specific CD8 T cell response in children

scientific article published on 27 June 2000

The relationship between T cell proliferative responses and plasma viremia during treatment of human immunodeficiency virus type 1 infection with combination antiretroviral therapy

scientific article published on 13 April 2000

The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection

article

Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

scientific article published in March 2012

Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection

scientific article

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection

scientific article published on 28 January 2014

Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses

scientific article published on July 2009

Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus

scientific article published on 08 October 2019

Treatment interruption in chronic HIV-1 infection: does it deliver?

scientific article published on January 2007

Tregs control the development of symptomatic West Nile virus infection in humans and mice

scientific article

Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic

scientific article

Variability of HIV-1 genomes among children and adolescents from São Paulo, Brazil

scientific article

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