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List of works by Erik Sahai

A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis

scientific article published on December 2008

A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

scientific article

A framework for advancing our understanding of cancer-associated fibroblasts

scientific article published on 24 January 2020

An open data ecosystem for cell migration research

scientific article

Arkadia regulates tumor metastasis by modulation of the TGF-β pathway.

scientific article published on 6 March 2013

Author Correction: STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy

scientific article published on 18 June 2020

Author Correction: TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

scientific article published in Nature Communications

Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts

scientific article published on 26 March 2012

Cancer dissemination--lessons from leukocytes

scientific article published on July 2010

Cell communication networks in cancer invasion ⬇️

scientific article published on May 11, 2011

Checking out the neighbourhood ⬇️

scientific article published on 01 November 2010

Chris Marshall 1949-2015.

scientific article published in September 2015

Classifying collective cancer cell invasion

scientific article published on August 2012

Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.

scientific article

Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis

scientific article

Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments

scientific article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

scientific article published on February 2001

Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination

scientific article published on 24 February 2020

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

scientific article

Deficits in axonal transport precede ALS symptoms in vivo

scientific article

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

scientific article

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

scientific article (publication date: August 2003)

Dissecting targeted therapy resistance: Integrating models to quantify environment mediated drug resistance

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

scientific article published on 01 July 2003

Editorial overview: Cell adhesion and migration

scientific article published on 29 August 2014

Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis

scientific article published on January 2006

Erik Sahai: getting the whole picture of metastasis. Interview by Sedwick Caitlin

scientific article published on May 2011

Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions

scientific article published on 28 October 2019

Extrinsic factors can mediate resistance to BRAF inhibition in central nervous system melanoma metastases

scientific article published on 28 September 2015

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

scientific article (publication date: December 2007)

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

scientific article published on 07 December 2020

Heterogeneity in tumor chromatin-doxorubicin binding revealed by in vivo fluorescence lifetime imaging confocal endomicroscopy.

scientific article published on 9 July 2018

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

scientific article

Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors

scientific article published in December 2004

Illuminating the metastatic process

scientific article published on October 2007

Imaging amoeboid cancer cell motility in vivo

scientific article published on September 2008

Imaging tumor cell movement in vivo

scientific article published on March 2013

Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes

scientific article

In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion

scientific article

Integrin beta1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

scientific article published on January 2005

Intravital imaging illuminates transforming growth factor beta signaling switches during metastasis

scientific article published on 27 April 2010

Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells

scientific article

Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling

scientific article

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination

scientific article

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

scientific article

Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility

scientific article

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

scientific article published on June 2005

Matrix feedback enables diverse higher-order patterning of the extracellular matrix

scientific article published on 28 October 2019

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

scientific article published on 23 June 2013

Mechanisms and impact of altered tumour mechanics

scientific article published on 27 June 2018

Mechanisms of cancer cell invasion

scientific article

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

scientific article published on 26 May 2013

Melanoma invasion - current knowledge and future directions

scientific article published on June 2007

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

scientific article

Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

scientific article

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

scientific article

New dimensions in cell migration

Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.

scientific article published on 6 January 2011

PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE.

scientific article published on 20 January 2008

Physical influences of the extracellular environment on cell migration

scientific article

Publisher Correction: Mechanisms and impact of altered tumour mechanics

scientific article published on 01 September 2018

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export.

scientific article published on 18 June 2018

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

scientific article published on 01 August 2011

ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo

scientific article published on August 2006

Rac activation and inactivation control plasticity of tumor cell movement

scientific article

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

scientific article published on 19 June 2011

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

scientific article

Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity

scientific article published on 05 November 2021

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1

scientific article

Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.

scientific article published on 26 September 2013

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

scientific article

Retrograde flow of cadherins in collective cell migration

scientific article published on 01 July 2014

Rho kinase inhibitors block melanoma cell migration and inhibit metastasis

scientific article

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

scientific article published on March 1998

STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy

scientific article published on 01 June 2020

STRIPAK components determine mode of cancer cell migration and metastasis.

scientific article published on 22 December 2014

Sds22, a PP1 phosphatase regulatory subunit, regulates epithelial cell polarity and shape [Sds22 in epithelial morphology].

scientific article

Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy

scientific article

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

scientific article

Stochastic Regulation of her1/7 Gene Expression Is the Source of Noise in the Zebrafish Somite Clock Counteracted by Notch Signalling

scientific article

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

scientific article published in Nature Communications

The actin cytoskeleton in cancer cell motility

scientific article published on 23 May 2008

Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors

scientific article published on 01 March 2019

Topological Tumor Graphs: A Graph-Based Spatial Model to Infer Stromal Recruitment for Immunosuppression in Melanoma Histology

scientific article published on 24 December 2019

Tumor cell migration in three dimensions

scientific article published on January 2006

Tumor cells caught in the act of invading: their strategy for enhanced cell motility

scientific article

Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness ⬇️

scientific article published on 18 January 2016

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism.

scientific article

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