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List of works by David Bernard

A genetic screen identifies topoisomerase 1 as a regulator of senescence.

scientific article

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

scientific article published on 01 March 2007

CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus.

scientific article

Calcium signaling and cellular senescence

scientific article

Cancer-Associated Fibroblasts Produce Netrin-1 to Control Cancer Cell Plasticity

scientific article published on 14 May 2019

Chemokine signaling via the CXCR2 receptor reinforces senescence

scientific article

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

scientific article published on 6 May 2014

Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors

article

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence.

scientific article published on 27 February 2014

Hepatic Stellate Cell Senescence in Liver Tumorigenesis

scientific article published on 15 September 2020

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

scientific article

Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells

scientific article published on 20 December 2014

Immortalization of primary human prostate epithelial cells by c-Myc.

scientific article

Instructive power of senescence

scientific article published on 01 October 2018

Involvement of Rel/nuclear factor-kappaB transcription factors in keratinocyte senescence.

scientific article published on January 2004

Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.

scientific article published on 10 October 2013

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

scientific article published on April 2016

MUC1 drives epithelial-mesenchymal transition in renal carcinoma through Wnt/β-catenin pathway and interaction with SNAIL promoter.

scientific article published on 30 December 2013

MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression

scientific journal article

MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes

scientific article

Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape.

scientific article

Myc represses transcription through recruitment of DNA methyltransferase corepressor

scientific article

NUAK1 links genomic instability and senescence.

scientific article published on June 2010

Normal or stress-induced fibroblast senescence involves COX-2 activity

scientific article published on 22 May 2007

PLA2R1 kills cancer cells by inducing mitochondrial stress.

scientific article published on 29 August 2013

PLA2R1 mediates tumor suppression by activating JAK2.

scientific article published on 5 September 2013

PLA2R1: expression and function in cancer

scientific article published on 22 March 2014

Protection from oxidative stress by enhanced glycolysis; a possible mechanism of cellular immortalization.

scientific article published on January 2007

Quantification of β-aminopropionitrile, an inhibitor of lysyl oxidase activity, in plasma and tumor of mice by liquid chromatography tandem mass spectrometry

scientific article published on 14 January 2014

Regulation of cellular senescence by retinoid X receptors and their partners

scientific article published on 30 August 2019

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

scientific article published on 11 May 2001

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

scientific article

Role of polycomb group proteins in stem cell self-renewal and cancer.

scientific article

Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program

scientific article published on 15 November 2015

TRPC3 shapes the ER-mitochondria Ca<sup>2+</sup> transfer characterizing tumour-promoting senescence

scientific article published on 17 February 2022

Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

scientific article published on 14 September 2018

The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes

scientific article published on 20 March 2020

The M-type receptor PLA2R regulates senescence through the p53 pathway

scientific article

The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action.

scientific article published on 04 April 2016

The Polycomb group protein EZH2 directly controls DNA methylation

scientific article

The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway.

scientific article published on 15 February 2018

The STATus of STAT3 in Lung Cell Senescence?

scientific article published on 01 July 2019

The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice

scientific article published on 03 October 2019

The methyl-CpG-binding protein MECP2 is required for prostate cancer cell growth

scientific article published on 01 March 2006

The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor

scientific article published on 21 October 2021

The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling

scientific article published on 14 September 2018

Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

scientific article published on 15 February 2018

Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells

scientific article published in 2022

[New physiopathological roles for the PLA2R1 receptor in cancer and membranous nephropathy]

scientific article published on 01 May 2014

[Senescent-associated factors: pro- and anti-tumoral actions]

scientific article published on 01 October 2009

cRel induces mitochondrial alterations in correlation with proliferation arrest

scientific article published on 01 October 2001

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