List of works - Marcello D'Amelio

A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

scientific article

A dual role of p53 in the control of autophagy

scientific article

A novel player in the p53-mediated autophagy: Sestrin2.

scientific article published on 15 May 2009

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

scientific article published on 01 December 2018

Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons.

scientific article

Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease

scientific article published on 2 February 2013

Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR.

scientific article

Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders

Analysis of neuronal cell death in mammals

scientific article published in January 2008

Apoptosome

article from 2010

Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse

scientific article published on 3 November 2015

Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease

scientific article published on 14 October 2019

Autophagy Inhibition Favors Survival of Rubrospinal Neurons After Spinal Cord Hemisection.

scientific article published on 11 August 2016

Aβ toxicity in Alzheimer's disease

scientific article published on 14 March 2012

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease

scientific article published on 02 September 2019

Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: From animal models to human findings ⬇️

scientific article published on July 10, 2012

CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit

scientific article published on 18 March 2013

Calcineurin Inhibition Rescues Early Synaptic Plasticity Deficits in a Mouse Model of Alzheimer’s Disease ⬇️

scientific article published on July 3, 2013

Caspase-3 in the central nervous system: beyond apoptosis

scientific article published on 14 July 2012

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

scientific article published on 12 December 2010

Chronic Lithium Treatment in a Rat Model of Basal Forebrain Cholinergic Depletion: Effects on Memory Impairment and Neurodegeneration

scientific article published on 7 February 2017

Cisd2: A promising new target in Alzheimer's disease

scientific article published on 24 March 2020

Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis

scientific article

Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease

article

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease.

scientific article

Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes

scientific article published in January 2009

Editorial: targeting synaptic dysfunction and neural connectivity in neurological and psychiatric disorders.

scientific article published in January 2013

Effects of Anti-NMDA Antibodies on Functional Recovery and Synaptic Rearrangement Following Hemicerebellectomy

scientific article

Epilepsy, amyloid-β, and D1 dopamine receptors: a possible pathogenetic link?

scientific article published on 3 September 2016

Erratum

scholarly article published in Autophagy

Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells

scientific article published on 01 June 2008

Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hippocampal epileptogenesis in autoimmune encephalitis

scientific article published on 15 October 2019

In vivo mapping of brainstem nuclei functional connectivity disruption in Alzheimer's disease

scientific article published on 23 August 2018

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

scientific article published on March 2009

Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory.

scientific article published on 3 June 2012

Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival.

scientific article published on 10 July 2009

Key role of mitochondria in Alzheimer's disease synaptic dysfunction.

scientific article published on January 2013

Matter of life and death: the pharmacological approaches targeting apoptosis in brain diseases.

scientific article published on January 2011

Mutations in the TMPRSS3 gene are a rare cause of childhood nonsyndromic deafness in Caucasian patients

scientific article (publication date: February 2002)

Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons.

scientific article

Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory

scientific article published on 7 February 2018

Neurodevelopmental Disorders: Functional Role of Ambra1 in Autism and Schizophrenia

scientific article published on 26 March 2019

Neuronal caspase-3 signaling: not only cell death

scientific article published on 04 December 2009

Neuroprotective Role of Dietary Supplementation with Omega-3 Fatty Acids in the Presence of Basal Forebrain Cholinergic Neurons Degeneration in Aged Mice

scientific article published on 04 March 2020

Neuroprotective effects of donepezil against cholinergic depletion

scientific article

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

scientific article published on November 2007

On the properties of identified dopaminergic neurons in the mouse substantia nigra and ventral tegmental area.

scientific article

Paraoxonase gene variants are associated with autism in North America, but not in Italy: possible regional specificity in gene-environment interactions.

scientific article

Persistent elevation of D-Aspartate enhances NMDA receptor-mediated responses in mouse substantia nigra pars compacta dopamine neurons.

scientific article published on 17 December 2015

Pleiotropic neuropathological and biochemical alterations associated with Myo5a mutation in a rat Model.

scientific article published on 4 December 2017

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release.

scientific article

RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models

scientific article published on 01 January 2019

Regulation of autophagy by cytoplasmic p53

scientific article

SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy

scientific article

Schwann cell autophagy counteracts the onset and chronification of neuropathic pain

scientific article published on 13 September 2013

Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

scientific article published on February 2012

The apoptosome: emerging insights and new potential targets for drug design

scientific article published on 3 August 2007

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

scientific article

The role of dopaminergic midbrain in Alzheimer's Disease: translating basic science into clinical practice.

scientific article published on 30 January 2018

The “Janus-Faced Role” of Autophagy in Neuronal Sickness: Focus on Neurodegeneration ⬇️

scientific article published on 07 July 2012

Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Aβ pathology

scientific article published on 04 February 2020

Transmission disequilibrium study of an oligodendrocyte and myelin glycoprotein gene allele in 431 families with an autistic proband

scientific article published on 19 August 2007

Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's Disease.

scientific article published on 17 May 2019

Unlocking the secrets of dopamine in Alzheimer's Disease

scientific article

Ventral Tegmental Area in Prodromal Alzheimer's Disease: Bridging the Gap between Mice and Humans

scientific article published on 30 March 2018

Ventral tegmental area disruption in Alzheimer's disease

scientific article published on 01 March 2019

List of works by Marcello D'Amelio

A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

A dual role of p53 in the control of autophagy

A novel player in the p53-mediated autophagy: Sestrin2.

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons.

Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease

Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR.

Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders

Analysis of neuronal cell death in mammals

Apoptosome

Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse

Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease

Autophagy Inhibition Favors Survival of Rubrospinal Neurons After Spinal Cord Hemisection.

Aβ toxicity in Alzheimer's disease

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease

Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: From animal models to human findings ⬇️

CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit

Calcineurin Inhibition Rescues Early Synaptic Plasticity Deficits in a Mouse Model of Alzheimer’s Disease ⬇️

Caspase-3 in the central nervous system: beyond apoptosis

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

Chronic Lithium Treatment in a Rat Model of Basal Forebrain Cholinergic Depletion: Effects on Memory Impairment and Neurodegeneration

Cisd2: A promising new target in Alzheimer's disease

Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis

Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease.

Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes

Editorial: targeting synaptic dysfunction and neural connectivity in neurological and psychiatric disorders.

Effects of Anti-NMDA Antibodies on Functional Recovery and Synaptic Rearrangement Following Hemicerebellectomy

Epilepsy, amyloid-β, and D1 dopamine receptors: a possible pathogenetic link?

Erratum

Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells

Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats.

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Hippocampal epileptogenesis in autoimmune encephalitis

In vivo mapping of brainstem nuclei functional connectivity disruption in Alzheimer's disease

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory.

Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival.

Key role of mitochondria in Alzheimer's disease synaptic dysfunction.

Matter of life and death: the pharmacological approaches targeting apoptosis in brain diseases.

Mutations in the TMPRSS3 gene are a rare cause of childhood nonsyndromic deafness in Caucasian patients

Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons.

Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory

Neurodevelopmental Disorders: Functional Role of Ambra1 in Autism and Schizophrenia

Neuronal caspase-3 signaling: not only cell death

Neuroprotective Role of Dietary Supplementation with Omega-3 Fatty Acids in the Presence of Basal Forebrain Cholinergic Neurons Degeneration in Aged Mice

Neuroprotective effects of donepezil against cholinergic depletion

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

On the properties of identified dopaminergic neurons in the mouse substantia nigra and ventral tegmental area.

Paraoxonase gene variants are associated with autism in North America, but not in Italy: possible regional specificity in gene-environment interactions.

Persistent elevation of D-Aspartate enhances NMDA receptor-mediated responses in mouse substantia nigra pars compacta dopamine neurons.

Pleiotropic neuropathological and biochemical alterations associated with Myo5a mutation in a rat Model.

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release.

RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models

Regulation of autophagy by cytoplasmic p53

SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy

Schwann cell autophagy counteracts the onset and chronification of neuropathic pain

Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

The apoptosome: emerging insights and new potential targets for drug design

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

The role of dopaminergic midbrain in Alzheimer's Disease: translating basic science into clinical practice.

The “Janus-Faced Role” of Autophagy in Neuronal Sickness: Focus on Neurodegeneration ⬇️

Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Aβ pathology

Transmission disequilibrium study of an oligodendrocyte and myelin glycoprotein gene allele in 431 families with an autistic proband

Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's Disease.

Unlocking the secrets of dopamine in Alzheimer's Disease

Ventral Tegmental Area in Prodromal Alzheimer's Disease: Bridging the Gap between Mice and Humans

Ventral tegmental area disruption in Alzheimer's disease