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List of works by Tobias Herold

A 17-gene stemness score for rapid determination of risk in acute leukaemia

scientific article published on 7 December 2016

A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.

scientific article published on 14 December 2017

A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia

scientific article published on 24 November 2015

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.

scientific article

Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia

scientific article

Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.

scientific article published on 16 September 2016

Added predictive value of omics data: specific issues related to validation illustrated by two case studies.

scientific article

Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

scientific article published on 25 August 2016

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

scientific article published on 13 August 2019

An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy

scientific article published on 01 December 2020

An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia

scientific article published on 31 May 2011

Breakthrough infection of Trichosporon asahii during posaconazole treatment in a patient with acute myeloid leukaemia

scientific article published on 01 November 2007

COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

scientific article published on 01 November 2021

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

scientific article published on 09 July 2020

Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia

scientific article published on 01 August 2019

Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia

scientific article published on 01 May 2020

Clonal heterogeneity of -ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia

scientific article published on 10 July 2018

Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia

scientific article

Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML

scientific article published on 26 June 2018

Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia

scientific article published on 26 July 2016

Dual PI3K/mTOR inhibition shows antileukemic activity in MLL-rearranged acute myeloid leukemia

scientific article published on 17 October 2014

Elevated levels of interleukin-6 and CRP predict the need for mechanical ventilation in COVID-19

scientific article published on 18 May 2020

Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.

scientific article published on 8 June 2016

Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: An exome sequencing study of 50 patients

scientific article published on 12 January 2018

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

scientific article

Extracorporeal Membrane Oxygenation in Predominantly Leuco- and Thrombocytopenic Haematologic/Oncologic Patients with Acute Respiratory Distress Syndrome - a Single-Centre Experience

scientific article published on 17 August 2018

GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia

scientific article published on 30 May 2012

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.

scientific article

Genetic heterogeneity of cytogenetically normal AML with mutations of

scientific article published on 01 October 2018

Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged ≥ 75 years

article

Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia

scientific article published on 31 May 2011

High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature

scientific article published on 27 December 2012

Hypoxia regulates proliferation of acute myeloid leukemia and sensitivity against chemotherapy

scientific article published on 7 May 2015

IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.

scientific article

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

scientific article published on 4 February 2013

In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets

scientific article published on 27 September 2021

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

scientific article published on 12 June 2014

Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients

scientific article published on 04 April 2020

Low-density lipoprotein receptor (LDLR) is an independent adverse prognostic factor in acute myeloid leukaemia

scientific article published on 08 June 2020

Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia

scientific article published on 26 July 2018

Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML

scientific article published on 08 July 2019

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia

scientific article published on 23 February 2018

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.

scientific article published on 18 December 2017

Ph-like acute lymphoblastic leukemia in older adults.

scientific article published in December 2014

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.

scientific article

Priority-Lasso: a simple hierarchical approach to the prediction of clinical outcome using multi-omics data

scientific article published on 12 September 2018

Progressive multifocal leukoencephalopathy after treatment with rituximab, fludarabine and cyclophosphamide in a patient with chronic lymphocytic leukemia

scientific article published on 19 September 2011

RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.

scientific article published on 16 September 2015

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

scientific article published on 11 June 2012

RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1.

scientific article published on 13 April 2015

SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine

scientific article published on 24 June 2020

Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma.

scientific article published on 2 February 2015

Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL.

scientific article published on 22 September 2016

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.

scientific article

Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow - A proof of concept study

scientific article published on 7 March 2018

TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition

scientific article published on 15 May 2020

The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

scientific article published on 01 November 2019

The clinical mutatome of core binding factor leukemia

scientific article published on 02 January 2020

The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia

scientific article

The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia

scientific article published on 10 June 2019

The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.

scientific article published on 21 December 2015

Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia

scientific article published on 30 March 2020

Venetoclax with azacitidine targets refractory MDS but spares healthy hematopoiesis at tailored dose

scientific article published on 16 April 2019

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.

scientific article published on 2 June 2016

[New treatment for chronic lymphocytic leukemia]

scientific article published on 01 January 2020

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

scientific article

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