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List of works by David T Clarke

A systematic investigation of differential effects of cell culture substrates on the extent of artifacts in single-molecule tracking.

scientific article

A tale of the epidermal growth factor receptor: The quest for structural resolution on cells.

scientific article

CD12: a new high-flux beamline for ultraviolet and vacuum-ultraviolet circular dichroism on the SRS, Daresbury

scientific article published on 12 February 2004

Circular Dichroism in Protein Folding Studies ⬇️

scientific article published on November 1, 2012

Circular dichroism and its use in protein-folding studies.

scientific article

Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution.

scientific article published on 18 April 2015

Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.

scientific article published on June 2015

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

scientific article

Effects of salts on the function and conformational stability of shikimate kinase

scientific article published in May 2003

Estimation of protein secondary structure from synchrotron radiation circular dichroism spectra

scientific article published on 01 January 2004

Extended circular dichroism measurements using synchrotron radiation show that the assembly of clathrin coats requires no change in secondary structure

scientific article

Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry

scientific article published on 28 March 2011

Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding

scientific article

Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives

scientific article published on 18 June 2007

Light flux density threshold at which protein denaturation is induced by synchrotron radiation circular dichroism beamlines

scientific article published on 8 May 2008

Limited interpretation of changes in the FTIR spectrum of beta-lactoglobulin with temperature

scientific article published on 01 November 1995

Measuring EGFR separations on cells with ~10 nm resolution via fluorophore localization imaging with photobleaching.

scientific article

Modulation of contact order effects in the two-state folding of stefins A and B.

scientific article

Multicolour single molecule imaging in cells with near infra-red dyes

scientific article

Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.

scientific article

Plications of extended ultra-violet circular dichroism spectroscopy in biology and medicine.

scientific article published on January 2004

Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes.

scientific article

Simultaneous widefield single molecule orientation and FRET microscopy in cells.

scientific article

Single molecule fluorescence detection and tracking in mammalian cells: the state-of-the-art and future perspectives

scientific article

Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.

scientific article

Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques

scientific article published on 28 December 2007

Structure, stability and folding of the alpha-helix

article

Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface.

scientific article published on February 2014

Synergistic use of synchrotron radiation techniques for biological samples in solution: a case study on protein-ligand recognition by the peroxisomal import receptor Pex5p.

scientific article published on 22 October 2004

The anti-sickling drug lawsone (2-OH-1,4-naphthoquinone) protects sickled cells against membrane damage

scientific article

The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea

scientific article published in April 2002

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3.

scientific article

X-ray diffraction and far-UV CD studies of filaments formed by a leucine-rich repeat peptide: structural similarity to the amyloid fibrils of prions and Alzheimer's disease beta-protein

scientific article published in July 1997

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