List of works - Fabienne Tacchini-Cottier

A new function of the Fas-FasL pathway in macrophage activation

scientific article published on 20 April 2009

Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses

scientific article

Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection

scientific article

An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced by Leishmania major infection

scientific article published on 01 March 2008

Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia

scientific article

Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection

scientific article

Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major

scientific article

Both the Fas ligand and inducible nitric oxide synthase are needed for control of parasite replication within lesions in mice infected with Leishmania major whereas the contribution of tumor necrosis factor is minimal

scientific article published on September 2003

Cross-presenting dendritic cells are required for control ofLeishmania majorinfection

scientific article published on 25 March 2014

Crosstalk between neutrophils and dendritic cells: a context-dependent process

scientific article published on 18 December 2012

Cutaneous leishmaniasis: progress towards a vaccine

scientific article published on October 2008

Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice

scientific article

Deletion of IL-4 Receptor alpha-responsive keratinocytes in BALB/c mice does not alter susceptibility to cutaneous leishmaniasis

scientific article published on 20 November 2018

Different Leishmania Species Drive Distinct Neutrophil Functions

scientific article published on March 2016

Differential peptide binding to CD40 evokes counteractive responses

article

Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model

scientific article published on 27 February 2012

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies

scientific article published on 13 November 2009

Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants

scientific article published on 16 November 2012

Erratum to “Differential peptide binding to CD40 evokes counteractive responses” [Human Immunology 73 (2012) 465–469]

article

Evaluation of a New Topical Treatment for the Control of Cutaneous Leishmaniasis

scientific article published on 17 November 2020

Exposure to Leishmania braziliensis triggers neutrophil activation and apoptosis

scientific article

Frontline Science: Leishmania mexicana amastigotes can replicate within neutrophils

scientific article published on 10 August 2017

Heat shock and proinflammatory stressors induce differential localization of heat shock proteins in human monocytes

scientific article published on 01 December 1997

IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis.

scientific article published on 21 April 2007

IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL/6 Mice.

scientific article

In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.

scientific article published in February 2009

Inactivation of E alpha and E beta expression in inbred and wild mice by multiple distinct mutations, some of which predate speciation within Mus species

scientific article

Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins

scientific article published on 01 November 2004

Interleukin-12p40 overexpression promotes interleukin-12p70 and interleukin-23 formation but does not affect bacille Calmette-Guérin and Mycobacterium tuberculosis clearance

scholarly article by Maria L Olleros et al published November 2007 in Immunology

Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis

scientific article published on 21 January 2009

LACK-reactive CD4+ T cells require autocrine IL-2 to mediate susceptibility to Leishmania major.

scientific article

Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection

scientific article

Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia

scientific article

M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis

scientific article published on 01 April 2020

Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage

scientific article published in October 2002

NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling

scientific article published on 23 October 2015

Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice

scientific article

Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani

scientific article

Neutrophils enhance early Trypanosoma brucei infection onset

scientific article published in Scientific Reports

New insight into the mechanisms underlying Th2 cell development and susceptibility to Leishmania major in BALB/c mice

scientific article

Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

scientific article published on 20 June 2016

Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner

scientific article published on 15 December 2016

Notch signaling regulates follicular helper T cell differentiation

scientific article published on 5 August 2013

Notch1 expression on T cells is not required for CD4+ T helper differentiation

scientific article published in June 2004

Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion

scientific article

Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major

scientific article

Regulation of innate and adaptive immunity by Notch

scientific article published on 13 May 2013

Regulation of protective immunity against Leishmania major in mice

scientific article published on 01 August 1998

Regulatory B cells shape the development of Th2 immune responses in BALB/c mice infected with Leishmania major through IL-10 production

scientific article

Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood

scientific article published on 09 January 2014

Resistance of to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions

scientific article published on 21 December 2018

Role of Toll-like receptor 9 signaling in experimental Leishmania braziliensis infection

scientific article published on 25 February 2013

Selective Expression of the Vβ14 T Cell Receptor onLeishmania guyanensis–Specific CD8+T Cells during Human Infection

scientific article published on 23 January 2007

Setting in motion the immune mechanisms underlying genetically determined resistance and susceptibility to infection with Leishmania major

scientific article published in May 1998

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

scientific article

Survival Mechanisms Used by Some Leishmania Species to Escape Neutrophil Killing.

scientific article published on 16 November 2017

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

scientific article published on 27 December 2018

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

scientific article published on 16 January 2014

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

scientific article

The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major.

scientific article published in June 2010

The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice

scientific article published on 22 December 2015

The prominent role of neutrophils during the initial phase of infection by Leishmania parasites

scientific article published on 25 October 2009

Toxoplasmic encephalitis

scientific article published on 01 November 1992

Transforming growth factor beta 1 production by CD4+ CD25+ regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis.

scientific article published in September 2005

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

scientific article published on 23 December 2013

List of works by Fabienne Tacchini-Cottier

A new function of the Fas-FasL pathway in macrophage activation

Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses

Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection

An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced by Leishmania major infection

Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia

Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection

Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major

Both the Fas ligand and inducible nitric oxide synthase are needed for control of parasite replication within lesions in mice infected with Leishmania major whereas the contribution of tumor necrosis factor is minimal

Cross-presenting dendritic cells are required for control ofLeishmania majorinfection

Crosstalk between neutrophils and dendritic cells: a context-dependent process

Cutaneous leishmaniasis: progress towards a vaccine

Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice

Deletion of IL-4 Receptor alpha-responsive keratinocytes in BALB/c mice does not alter susceptibility to cutaneous leishmaniasis

Different Leishmania Species Drive Distinct Neutrophil Functions

Differential peptide binding to CD40 evokes counteractive responses

Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies

Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants

Erratum to “Differential peptide binding to CD40 evokes counteractive responses” [Human Immunology 73 (2012) 465–469]

Evaluation of a New Topical Treatment for the Control of Cutaneous Leishmaniasis

Exposure to Leishmania braziliensis triggers neutrophil activation and apoptosis

Frontline Science: Leishmania mexicana amastigotes can replicate within neutrophils

Heat shock and proinflammatory stressors induce differential localization of heat shock proteins in human monocytes

IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis.

IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL/6 Mice.

In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.

Inactivation of E alpha and E beta expression in inbred and wild mice by multiple distinct mutations, some of which predate speciation within Mus species

Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins

Interleukin-12p40 overexpression promotes interleukin-12p70 and interleukin-23 formation but does not affect bacille Calmette-Guérin and Mycobacterium tuberculosis clearance

Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis

LACK-reactive CD4+ T cells require autocrine IL-2 to mediate susceptibility to Leishmania major.

Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection

Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia

M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis

Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage

NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling

Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice

Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani

Neutrophils enhance early Trypanosoma brucei infection onset

New insight into the mechanisms underlying Th2 cell development and susceptibility to Leishmania major in BALB/c mice

Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner

Notch signaling regulates follicular helper T cell differentiation

Notch1 expression on T cells is not required for CD4+ T helper differentiation

Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion

Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major

Regulation of innate and adaptive immunity by Notch

Regulation of protective immunity against Leishmania major in mice

Regulatory B cells shape the development of Th2 immune responses in BALB/c mice infected with Leishmania major through IL-10 production

Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood

Resistance of to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions

Role of Toll-like receptor 9 signaling in experimental Leishmania braziliensis infection

Selective Expression of the Vβ14 T Cell Receptor onLeishmania guyanensis–Specific CD8+T Cells during Human Infection

Setting in motion the immune mechanisms underlying genetically determined resistance and susceptibility to infection with Leishmania major

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

Survival Mechanisms Used by Some Leishmania Species to Escape Neutrophil Killing.

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major.

The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice

The prominent role of neutrophils during the initial phase of infection by Leishmania parasites

Toxoplasmic encephalitis

Transforming growth factor beta 1 production by CD4+ CD25+ regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis.

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

UNDERSTANDING MICROBIAL PATHOGENESIS AS A BASIS FOR VACCINE DESIGN