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List of works by David R Owen

(11)C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than (11)C-( R)-PK11195.

scientific article

11C-PBR28 and 18F-PBR111 Detect White Matter Inflammatory Heterogeneity in Multiple Sclerosis

scientific article

A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [¹¹C]PBR28 and [¹⁸F]PBR111 for TSPO imaging

scientific article

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

scientific article published on 01 November 2019

Advances in positron emission tomography for the imaging of rheumatoid arthritis.

scientific article published on 9 February 2017

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

scientific article

Are prescribed benzodiazepines likely to affect the availability of the 18 kDa translocator protein (TSPO) in PET studies?

scientific article

Assessment of Global Liver Blood Flow With Quantitative Dynamic Contrast-Enhanced Ultrasound ⬇️

scientific article published on March 1, 2011

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).

scientific article published on 12 August 2013

Clinical assessment of carotid atherosclerosis inflammation by positron emission tomography

scientific article published on December 2013

Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios

scientific article published on 16 October 2017

Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter

scientific article published on 01 October 2019

Corrigendum: Phagocytosis in the Brain: Homeostasis and Disease

scientific article published on 10 July 2019

Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases

scientific article published on 26 July 2021

Decreased hippocampal translocator protein (18 kDa) expression in alcohol dependence: a [11C]PBR28 PET study

scientific article published on 10 January 2017

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study

scientific article

Direct and indirect effects of immune and central nervous system-resident cells on human oligodendrocyte progenitor cell differentiation

Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology

scientific article published on 12 November 2021

Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1-Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging.

scientific article

Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

scientific article published on 05 December 2015

Identification and assessment of plasma lysozyme as a putative biomarker of atherosclerosis

scientific article

Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo

scientific article published on 10 January 2012

Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography

scientific article published on 19 September 2011

Imaging of atherosclerosis

scientific article

In Response to Letter from Fregonara et al. 2019

scientific article published on 01 February 2020

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

scientific article

Inflammation within carotid atherosclerotic plaque: assessment with late-phase contrast-enhanced US

scientific article published on 01 May 2010

Intravenous Furosemide for Acute Decompensated Congestive Heart Failure: What Is the Evidence?

scientific article published on 30 June 2015

Late-Phase Contrast-Enhanced Ultrasound Reflects Biological Features of Instability in Human Carotid Atherosclerosis

scientific article published on 29 September 2011

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study.

scientific article published on 16 October 2015

Microglial positron emission tomography (PET) imaging in epilepsy: Applications, opportunities and pitfalls.

scientific article published on 13 November 2016

Motion-sensitized driven equilibrium for blood-suppressed T2* mapping

scientific article published on 18 July 2011

Phagocytosis in the Brain: Homeostasis and Disease

scientific article published on 16 April 2019

Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity

scientific article published on 23 December 2015

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

scientific article published on January 2017

Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding.

scientific article published on 26 September 2013

Roles of microglia in brain development, tissue maintenance and repair.

scientific article published on 29 March 2015

Stratified medicine in psychiatry: a worrying example or new opportunity in the treatment of anxiety?

scientific article published on 20 April 2012

TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.

scientific article published on 26 October 2017

The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages

scientific article published on 2 October 2017

Translocator protein as an imaging marker of macrophage and stromal activation in RA pannus

scientific article published on 4 January 2018

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

scientific article

Using prescribing very short answer questions to identify sources of medication errors: a prospective study in two UK medical schools

scientific article published on 09 July 2019

Using team-based revision to prepare medical students for the prescribing safety assessment

scientific article published on 10 July 2019

Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain

scientific article published on 01 March 2011

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