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List of works by Friedrich Grimminger

A Combination Hybrid-Based Vaccination/Adoptive Cellular Therapy to Prevent Tumor Growth by Involvement of T Cells

scientific article published in June 2007

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

scientific article published on 13 May 2019

A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis

scientific article published in August 1993

A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis

scientific article

A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension

scientific article published on 20 April 2009

ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension

scientific article published on 14 September 2017

Abnormalities of Gastric Mucosal Oxygenation in Septic Shock

scientific article published on 01 May 1998

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Acceleration of experimental diabetic retinopathy in the rat by omega-3 fatty acids

scientific article published on 01 March 1996

Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.

scientific article published on 31 January 2012

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

scientific article published on 3 January 2006

Acute effects of phosphodiesterase 5 (PDE5) inhibition, ANP and NO on epididymal contractility are preserved despite chronic PDE5 exposure.

scientific article published in August 2011

Acute effects of riociguat in borderline or manifest pulmonary hypertension associated with chronic obstructive pulmonary disease

scientific article published on June 2015

Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension

scientific article published on 9 July 2008

Advantage of buffered solutions or automated capnometry in air-filled balloons for use in gastric tonometry

scientific article published on 01 April 1997

Aerosolised prostacyclin in adult respiratory distress syndrome

scientific article

Aerosolized PGE1, PGI2 and nitroprusside protect against vascular leakage in lung ischaemia-reperfusion.

scientific article published in July 2001

Aerosolized Prostacyclin and Iloprost in Severe Pulmonary Hypertension

scientific article published on 01 May 1996

Aerosolized vasodilators in pulmonary hypertension

scientific article

Air travel can be safe and well tolerated in patients with clinically stable pulmonary hypertension.

scientific article published on April 2011

Alteration of fatty acid profiles in different pulmonary surfactant phospholipids in acute respiratory distress syndrome and severe pneumonia.

scientific article

Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease

scientific article published in November 2002

Altered proteasome function in right ventricular hypertrophy

scientific article published on 01 February 2020

Alveolar Fibrin Formation Caused by Enhanced Procoagulant and Depressed Fibrinolytic Capacities in Severe Pneumonia

scientific article published on 01 February 2000

Alveolar antioxidant status in patients with acute respiratory distress syndrome

scientific article published in December 2004

Alveolar surfactant and adult respiratory distress syndrome. Pathogenetic role and therapeutic prospects

scientific article

Amelioration of elastase-induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice

scientific article published on 22 March 2020

Amplification of lipopolysaccharide-induced cytokine synthesis in non-small cell lung cancer/neutrophil cocultures

scientific article published on 13 October 2009

Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension

scientific article published in November 2002

Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis

scientific article published on 19 December 2016

An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid

scientific article published in February 2002

Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA

scientific article published in January 2007

Analysis of tumor vessel supply in Lewis lung carcinoma in mice by fluorescent microsphere distribution and imaging with micro- and flat-panel computed tomography

scientific article published on October 2005

Anti-proteinase 3 antibodies (c-ANCA) prime CD14-dependent leukocyte activation

scientific article published on 8 July 2005

Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension

scientific article published on 18 March 2004

Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis

scientific article

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

scientific article

Arachidonic Acid Lipoxygenase Pathways and Increased Vascular Permeability in Isolated Rabbit Lungs

scientific article published on 01 October 1987

Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.

scientific article published on February 2014

Assessment of intestinal tissue oxygenation: the canary sings--but was does the twitter tell us?

scientific article published in August 2000

Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo-controlled, dose-ranging study

scientific article

Atrial natriuretic peptide in severe primary and nonprimary pulmonary hypertension: response to iloprost inhalation.

scientific article

Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

scientific article published on 01 July 2020

Basic features of hypoxic pulmonary vasoconstriction in mice

scientific article (publication date: 15 January 2004)

Biomarkers of tissue remodeling predict survival in patients with pulmonary hypertension

scientific article published on 13 August 2016

Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema

scientific article published on 01 September 1996

Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on biophysical and biochemical surfactant properties

scientific article published in May 2002

Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: impact on gas exchange and haemodynamics

scientific article published in May 2002

Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis

scientific article published on 01 July 1996

Burden of pulmonary arterial hypertension in Germany

scientific article published on 9 February 2010

COPD-associated pulmonary hypertension: clinical implications and current methods for treatment

scientific article published on 21 May 2016

Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors

scientific article published in May 2001

Cellular and molecular mechanisms of hypoxia-inducible factor driven vascular remodeling

scientific article published on 01 May 2007

Cellular pathophysiology and therapy of pulmonary hypertension.

scientific article

Central sleep apnoea and unilateral diaphragmatic paralysis associated with vertebral artery compression of the medulla oblongata

scientific article

Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.

scientific article

Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin

scientific article

Chemical crosslinking of urokinase to pulmonary surfactant protein B for targeting alveolar fibrin.

scientific article

Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension

scientific article published on 31 March 2017

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

scientific article published on 4 September 2003

Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis

scientific article published on 25 June 2015

Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice

scientific article published on 9 June 2015

Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension

scientific article

Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange

scholarly article

Cleavage of Surfactant-Incorporating Fibrin by Different Fibrinolytic Agents

scientific article published on 01 December 1999

Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension

scientific article

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.

scientific article

Combined human papillomavirus typing and TP53 mutation analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma

scientific article published on 09 March 2018

Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling

scientific article published on 27 October 2008

Comparison of hemodynamic parameters in treatment-naïve and pre-treated patients with pulmonary arterial hypertension in the randomized phase III PATENT-1 study.

scientific article published on 24 December 2016

Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development

scientific article published in January 2006

Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application

scientific article

Compartmentalized lung cytokine release in response to intravascular and alveolar endotoxin challenge

scientific article published on 01 January 1996

Conebulization of surfactant and urokinase restores gas exchange in perfused lungs with alveolar fibrin formation

scientific article published on 01 April 2001

Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia

scientific article (publication date: September 2005)

Correction: Improvement of right heart structure and function by BAY41-8543 in pulmonary artery banded mice.

scientific article published on 14 September 2011

Cyclooxygenase isoenzyme localization and mRNA expression in rat lungs

scientific article published in April 1998

Cyclosporine-induced coronary artery constriction—dissociation between thromboxane release and coronary vasospasm

scientific article published in April 1999

Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling

scientific article

Cytochrome P450 epoxygenase-derived 5,6-epoxyeicosatrienoic acid relaxes pulmonary arteries in normoxia but promotes sustained pulmonary vasoconstriction in hypoxia

scientific article published on 07 June 2020

DNA transfer into human lung cells is improved with Tat-RGD peptide by caveoli-mediated endocytosis

scientific article published in March 2006

Dana Point: what is new in the treatment of pulmonary hypertension?

scientific article published on 23 September 2008

Detection of an activated JAK3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis.

scientific article published on 23 February 2014

Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy

scientific article

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6.

scientific article published on 4 February 2011

Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study

scientific article published in October 2004

Differential Impact of Ultrasonically Nebulized Versus Tracheal-instilled Surfactant on Ventilation-Perfusion (V˙A/Q˙) Mismatch in a Model of Acute Lung Injury

scientific article published on 01 January 2000

Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension.

scientific article

Differential vasoconstrictor potencies of free fatty acids in the lung vasculature: 2-versus 3-series prostanoid generation

scientific article published on 01 October 1993

Direct and simultaneous profiling of epoxyeicosatrienoic acid enantiomers by capillary tandem column chiral-phase liquid chromatography with dual online photodiode array and tandem mass spectrometric detection

scientific article

Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome

scientific article published on 01 March 1996

Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection

scientific article

Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.

scientific article published in October 2002

Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide

scientific article published on 14 November 2002

E. coli hemolysin-induced lipid mediator metabolism in alveolar macrophages: impact of eicosapentaenoic acid.

scientific article published in July 2000

Effect of 3 hours of passive smoke exposure in the evening on inflammatory markers in bronchoalveolar and nasal lavage fluid in subjects with mild asthma

scientific article published on 01 January 1997

Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock

scientific article published on 01 April 2006

Effect of sildenafil on hypoxia-induced changes in pulmonary circulation and right ventricular function

article published in 2007

Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling

scientific article published on 14 August 2013

Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 May 1995

Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis

scientific article published on 01 March 1995

Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs

scientific article published on 01 September 1998

Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.

scientific article published on September 2013

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction.

scientific article published on 31 January 2012

Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction.

scientific article published on 28 August 2009

Effects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension

scientific article published on 01 May 1997

Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

scientific article published on 01 October 2020

Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs

scientific article

Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling.

scientific article

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

scientific article

Effects of riociguat in severe experimental pulmonary hypertension.

scientific article published in August 2011

Efficiency of aerosolized nitric oxide donor drugs to achieve sustained pulmonary vasodilation

scientific article published on 01 August 1997

Emerging therapies for the treatment of pulmonary arterial hypertension

scientific article published in June 2005

Endogenous Nitric Oxide Synthesis and Vascular Leakage in Ischemic-Reperfused Rabbit Lungs

scientific article published on 01 August 2001

Endothelial responses to bacterial toxins in sepsis.

scientific article published on January 2003

Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.

scientific article published on 26 August 2012

Endotoxin primes perfused rabbit lungs for enhanced vasoconstrictor response to staphylococcal alpha-toxin

scientific article published in November 1993

Endotoxin priming of the cyclooxygenase-2-thromboxane axis in isolated rat lungs

scientific article published on 01 June 2000

Endotoxin-Induced Myocardial Tumor Necrosis Factor-α Synthesis Depresses Contractility of Isolated Rat Hearts

scientific article published on 01 November 2000

Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy

scientific article published in August 2000

Epithelial cell plasticity defines heterogeneity in lung cancer

scientific article published on 03 November 2019

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension

scientific article published on 2 March 2018

Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge

scientific article published on 8 April 2010

Evaluating Systolic and Diastolic Cardiac Function in Rodents Using Microscopic Computed Tomography

scientific article published on 01 December 2018

Evaluation and Prognostic Relevance of Right Ventricular-Arterial Coupling in Pulmonary Hypertension

scientific article published on 01 January 2020

Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer

scientific article published on January 2009

Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction

article

Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension

scientific article published on 01 June 2019

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

scientific article published on 16 September 2009

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

scientific article

Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases

FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction

scientific article published on 24 January 2020

Favorable effects of inhaled treprostinil in severe pulmonary hypertension: results from randomized controlled pilot studies

scientific article published on 26 September 2006

Fhl-1, a new key protein in pulmonary hypertension.

scientific article

Fibrinolysis-inhibitory capacity of clot-embedded surfactant is enhanced by SP-B and SP-C

scientific article published on 06 September 2002

Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas

scientific article published on 22 July 2020

Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system

scientific article published in 2022

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

scientific article

Fish oil fatty acids and human platelets: Dose-dependent decrease in dienoic and increase in trienoic thromboxane generation

scientific article published on 01 October 1996

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis

scientific article

Free arachidonic versus eicosapentaenoic acid differentially influences the potency of bacterial exotoxins to provoke myocardial depression in isolated rat hearts

scientific article published in January 2006

Function of NADPH oxidase 1 in pulmonary arterial smooth muscle cells after monocrotaline-induced pulmonary vascular remodeling

scientific article published on 20 July 2013

Functional role and species-specific contribution of arginases in pulmonary fibrosis

scientific article published on 12 October 2007

Future aspects of the treatment of pulmonary arterial hypertension

scientific article published in December 2006

Future perspectives for the treatment of pulmonary arterial hypertension

scientific article published on June 2009

Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

scientific article published on 30 November 2020

Genetic Deletion of p66shc and/or Cyclophilin D Results in Decreased Pulmonary Vascular Tone

scientific article published on 29 October 2020

Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia

scientific article

Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.

scientific article

HIF-1alpha attenuates tumor growth in spite of augmented vascularization in an A549 adenocarcinoma mouse model

scientific article published on August 2005

HIV-associated pulmonary hypertension

scientific article

Haemodynamic effects of riociguat in inoperable/recurrent chronic thromboembolic pulmonary hypertension.

scientific article published on 23 December 2016

Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia.

scientific article

High yield enzymatic conversion of intravascular leukotriene A4 in blood-free perfused lungs

scientific article published on 01 October 1988

Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

scientific article

Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia

scientific article

Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors

scientific article published on February 2001

Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin.

scientific article published on August 1997

Human leukoagglutinating antibody evokes cooperative leukotriene synthesis in pulmonary microvasculature. Model of transfusion-related acute lung injury

scientific article published in February 1991

Hybrid-Primed Lymphocytes and Hybrid Vaccination Prevent Tumor Growth of Lewis Lung Carcinoma in Mice

scientific article published on 01 March 2006

Hydrogen Peroxide-Induced Increase in Lung Endothelial and Epithelial Permeability-Effect of Adenylate Cyclase Stimulation and Phosphodiesterase Inhibition

scientific article published on 01 July 1995

Hypoxia in lung vascular biology and disease

scientific article published on 11 July 2006

Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species

scientific article published on 16 December 2011

Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies.

scientific article published on August 2006

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature

scientific article

Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1α and an autocrine angiotensin system

scientific article published on 17 February 2005

Hypoxia-induced pulmonary hypertension: Different impact of iloprost, sildenafil, and nitric oxide

scientific article published on 20 July 2007

Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors

scientific article published on 21 August 2002

Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

scientific article

Hypoxic pulmonary vasoconstriction in isolated mouse pulmonary arterial vessels

scientific article published on 06 July 2018

Hypoxic pulmonary vasoconstriction--triggered by an increase in reactive oxygen species?

scientific article published on 01 January 2006

Hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 May 1995

IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension

scientific article published on 13 October 2020

Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells.

scientific article published on April 2005

Idiopathic Interstitial Pneumonias: Pathomechanisms and Therapeutic Options

scientific article published on 01 August 2005

Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs

scientific article (publication date: 26 January 2007)

Imatinib for the treatment of pulmonary arterial hypertension

scientific article

Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy.

scientific article

Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study.

scientific article

Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma

scientific article published on 28 September 2015

Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension

scientific article published on 6 September 2012

Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

scientific article

Immunomodulation by n-3- versus n-6-rich lipid emulsions in murine acute lung injury—Role of platelet-activating factor receptor

scientific article published on 01 February 2007

Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia

scientific article published on November 2005

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling

scientific article published on 27 January 2014

Impact of arachidonic versus eicosapentaenoic acid on exotonin-induced lung vascular leakage: relation to 4-series versus 5-series leukotriene generation

scientific article published on 01 February 1997

Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction

scientific article published on 15 December 2005

Impact of surface tension on the conversion rate of large to small surfactant aggregates

scientific article published on 01 May 2003

Improved fatty acid and leukotriene pattern with a novel lipid emulsion in surgical patients

scientific article published on 22 July 2005

Improvement of right heart structure and function by BAY 41-8543 in pulmonary artery banded mice.

scientific article published in August 2011

In situ localization and regulation of thromboxane A(2) synthase in normal and LPS-primed lungs

scientific article published on 01 April 2000

In situ localization of TNFalpha/beta, TACE and TNF receptors TNF-R1 and TNF-R2 in control and LPS-treated lung tissue

scientific journal article

In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFalpha impact of omega-3 versus omega-6 fatty acids

scientific article published in June 2002

In vivo TRPC functions in the cardiopulmonary vasculature.

scientific article published on 11 April 2007

Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia

scientific article

Increased LTB4 metabolites and PGD2 in BAL fluid after methacholine challenge in asthmatic subjects

scientific article published on 01 March 1993

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention

scientific article published on 29 July 2010

Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension

scientific article published on 12 April 2005

Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost

scientific article published in December 2003

Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases

scientific journal article

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

scientific article published on 01 October 2011

Induction of Vascular Injury by Pseudomonas aeruginosa Cytotoxin in Rabbit Lungs Is Associated with the Generation of Different Leukotrienes and Hydroxyeicosatetraenoic Acids

scientific article published on 01 February 1991

Inflammation, growth factors, and pulmonary vascular remodeling

scientific article published on June 2009

Inflammation, immunological reaction and role of infection in pulmonary hypertension.

scientific article published on January 2011

Influence of intravenous n-3 lipid supplementation on fatty acid profiles and lipid mediator generation in a patient with severe ulcerative colitis

scientific article published in November 1993

Inhalative strategies for improvement of pulmonary hemodynamics and gas exchange in sepsis and severe pulmonary hypertension

scientific article

Inhaled iloprost is a potent acute pulmonary vasodilator in HIV-related severe pulmonary hypertension.

scientific article published on February 2004

Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension

scientific article published on 5 May 2005

Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis

scientific article

Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to pulmonary fibrosis

scientific article

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration

scientific article

Inhaled treprostinil [corrected] for treatment of chronic pulmonary arterial hypertension

scientific article published in January 2006

Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.

scientific article published on October 1991

Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension

scientific article published on 8 December 2011

Inhibition of phosphodiesterase 4 enhances lung alveolarisation in neonatal mice exposed to hyperoxia.

scientific article

Interaction of antibodies to proteinase 3 (classic anti-neutrophil cytoplasmic antibody) with human renal tubular epithelial cells: impact on signaling events and inflammatory mediator generation

scientific article published in March 2002

Interactions between neutrophils and non-small cell lung cancer cells: enhancement of tumor proliferation and inflammatory mediator synthesis

scientific article published on 4 September 2014

Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model

scientific article

Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats

scientific article

Is PKM2 Phosphorylation a Prerequisite for Oligomer Disassembly in Pulmonary Arterial Hypertension?

scientific article published on 01 December 2019

Is there a reliable immunotherapy in infection?

scientific article published in June 1997

Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction

scientific article published on 10 November 2019

Leukotriene and hydroxyeicosatetraenoic acid generation elicited by low doses of Escherichia coli hemolysin in rabbit lungs.

scientific article published on August 1990

Leukotriene-mediated coronary vasoconstriction and loss of myocardial contractility evoked by low doses of Escherichia coli hemolysin in perfused rat hearts

scientific article published in March 2003

Leukotrienes and ARDS

scientific article published on 01 January 1991

Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply.

scientific article published in April 1992

Lipid mediators, free fatty acids and psoriasis.

scientific article

Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: Autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 gen

scientific article

Lipoteichoic acids from Staphylococcus aureus stimulate proliferation of human non-small-cell lung cancer cells in vitro

scientific article published on 17 March 2017

Listeriolysin is a potent inducer of the phosphatidylinositol response and lipid mediator generation in human endothelial cells.

scientific article

Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension

scientific article published on 21 June 2018

Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension

scientific article published on 09 August 2007

Low-dose Systemic Phosphodiesterase Inhibitors Amplify the Pulmonary Vasodilatory Response to Inhaled Prostacyclin in Experimental Pulmonary Hypertension

scientific article published on 01 November 1999

Lung cGMP release subsequent to NO inhalation in pulmonary hypertension: responders versus nonresponders

scientific article

Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk

scientific article

Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

scientific article

Macrophage and Tumor Cell Cross-Talk Is Fundamental for Lung Tumor Progression: We Need to Talk

scientific article published on 11 March 2020

Macrophage and cancer cell cross-talk via CCR2 and CX3CR1 is a fundamental mechanism driving lung cancer

scientific article published on February 2015

Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.

scientific article

Maintained right ventricular pressure overload induces ventricular-arterial decoupling in mice

scientific article published on 19 December 2016

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

scientific article published on 25 February 2013

Measurement of exhaled hydrogen peroxide from rabbit lungs

scientific article

Mechanisms of cardiac depression caused by lipoteichoic acids from Staphylococcus aureus in isolated rat hearts

scientific article published on 25 July 2005

Mechanisms of disease: pulmonary arterial hypertension.

scientific article published on 21 June 2011

Mediator generation and signaling events in alveolar epithelial cells attacked by S. aureus alpha-toxin.

scientific article published on February 2002

Medikamentöse Therapie der pulmonalen Hypertonie

scientific article published on 01 May 2015

Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment

scientific article published on 01 September 2020

Metastasis-associated protein 2 represses NF-ƙB to reduce lung tumor growth and inflammation

scientific article published on 14 August 2020

Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension

scientific article

Microcirculatory dysfunction in the brain precedes changes in evoked potentials in endotoxin-induced sepsis syndrome in rats

scientific article published on 16 November 2006

Microenvironmental Th9- and Th17- lymphocytes induce metastatic spreading in lung cancer

scientific article published on 31 March 2020

Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing

scientific article published on 15 June 2017

Mitochondrial cytochrome redox states and respiration in acute pulmonary oxygen sensing

scientific article published on 01 June 2010

Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model

scientific article published in September 2013

Modulating cGMP to treat lung diseases.

scientific article published on January 2009

NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

scientific article published on 08 June 2020

NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs.

scientific article

NO und alternative inhalative Therapieansätze bei pulmonaler Hypertonie

scientific article published on 01 May 1997

NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts

scientific article published in October 2008

Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features

scientific article

Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction

scientific article published on 21 June 2010

New potential diagnostic biomarkers for pulmonary hypertension.

scientific article published on 6 August 2015

New trial designs and potential therapies for pulmonary artery hypertension

scientific article

New trial designs and potential therapies for pulmonary artery hypertension

scientific article published in October 2014

Nintedanib in Severe Pulmonary Arterial Hypertension.

scientific article

Nitric Oxide Biosynthesis in an Exotoxin-induced Septic Lung Model

scientific article published on 01 February 1998

Nitric oxide (NO)-dependent but not NO-independent guanylate cyclase activation attenuates hypoxic vasoconstriction in rabbit lungs

scientific article published in August 2000

Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs

scientific article published on 01 April 1995

Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension.

scientific article published on June 2004

Nitro blue tetrazolium inhibits but does not mimic hypoxic vasoconstriction in isolated rabbit lungs.

scientific article published in May 1998

Nocturnal periodic breathing in primary pulmonary hypertension

scientific article published in April 2002

Non-invasive Surrogate Markers of PH are Associated with Poor Survival in Lung Cancer Patients

scientific article published on 07 January 2021

Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.

scientific article

Novel and emerging therapies for pulmonary hypertension

scientific article published on February 2014

Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury

scientific article

Nutrition and immunonutrition in septic patients

scientific article published in April 2006

Obstructive Sleep Apnoea and Cardiovascular Diseases - Hypothesis of Pathophysiological Interlinks

scientific article published on 01 June 2001

Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome?

scientific article

Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation

scientific article

Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation

scientific article published on 25 July 2003

Omega-oxidized leukotriene B4 detected in the broncho-alveolar lavage fluid of patients with non-cardiogenic pulmonary edema, but not in those with cardiogenic edema

scientific article published on 01 January 1991

On-line measurement of nitric oxide generation in buffer-perfused rabbit lungs

scientific article published on 01 April 1995

Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension

scientific article published on July 2003

Oxygen sensors in hypoxic pulmonary vasoconstriction

scientific article published on September 2006

PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung

scientific article published on 01 February 2000

PDGF receptor and its antagonists: role in treatment of PAH.

scientific article published on January 2010

Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis

scientific article

Parenteral nutrition with n-3 lipids in sepsis.

scientific article

Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

scientific article published on 21 November 2007

Pathophysiology of acute lung injury.

scientific article

Pharmacokinetics and metabolism of infused versus inhaled iloprost in isolated rabbit lungs

scientific article published in November 2002

Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome

scientific article published on 01 July 2000

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

scientific article

Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling

scientific article

Phosphodiesterase 5 (PDE5) inhibition, ANP and NO rapidly reduce epididymal duct contractions, but long-term PDE5 inhibition in vivo does not.

scientific article

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

scientific article

Phosphodiesterase inhibitors for the treatment of pulmonary hypertension

scientific article published in July 2008

Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF.

scientific article

Physiologic basis for the treatment of pulmonary hypertension.

scientific article

Physiologie und Pathophysiologie der pulmonalen Zirkulation

scientific article published on 01 July 1999

Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells.

scientific article published on July 1993

Predictors of long-term outcomes in patients treated with riociguat for chronic thromboembolic pulmonary hypertension: data from the CHEST-2 open-label, randomised, long-term extension trial

scientific article

Predictors of long-term outcomes in patients treated with riociguat for pulmonary arterial hypertension: data from the PATENT-2 open-label, randomised, long-term extension trial.

scientific article

Pressure overload leads to an increased accumulation and activity of mast cells in the right ventricle

scientific article

Prevention and therapy of the adult respiratory distress syndrome.

scientific article

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits

scientific article

Pro- and antifibrinolytic properties of human pulmonary microvascular versus artery endothelial cells: impact of endotoxin and tumor necrosis factor-alpha.

scientific article published in January 2004

Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension

scientific article published on 26 October 2014

Procedural safety of a fully implantable intravenous prostanoid pump for pulmonary hypertension.

scientific article published on 26 September 2016

Prostacyclin Enhances Stretch-induced Surfactant Secretion in Alveolar Epithelial Type II Cells

scientific article published on 01 September 1999

Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection

scientific article published on July 1994

Prävalenz von Schlaganfall und transitorischer ischämischer Attacke (TIA) bei obstruktiver Schlaf-Apnoe: eine retrospektive Erhebung an 187 konsekutiven Patienten1

scientific article published on 01 December 2000

Pulmonale Hypertonie bei COPD und interstitiellen Lungenerkrankungen

scientific article published in August 2009

Pulmonaler Hochdruck

scientific article published on 01 December 2002

Pulmonary Hemodynamic Response to Exercise in Chronic Thromboembolic Pulmonary Hypertension before and after Pulmonary Endarterectomy

scientific article published on 3 June 2015

Pulmonary hypertension: updated classification and management of pulmonary hypertension

scientific article published on April 2010

Pulmonary vascular disease in the developing world.

scientific article published on October 2008

RNA interference for HIF-1alpha inhibits its downstream signalling and affects cellular proliferation

scientific article published on December 2003

Rat pulmonary cyclooxygenase-2 expression in response to endotoxin challenge: differential regulation in the various types of cells in the lung

scientific article published on April 2000

Recovery from circulatory shock in severe primary pulmonary hypertension (PPH) with aerosolization of iloprost

scientific article published on 01 June 1998

Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction

scientific article published on 27 August 2010

Regeneration von Lungenparenchym - eine Chance für die Zukunft

scientific article published on 01 April 2006

Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms.

scientific article

Reply to Bogaard et al.: Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension

scientific article published on 01 December 2019

Reproduction of transfusion-related acute lung injury in an ex vivo lung model

scientific article published on 01 October 1990

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

scientific article published on 05 June 2020

Reversal of experimental pulmonary hypertension by PDGF inhibition

scientific article

Reverse remodeling -- paradigm shift in the treatment of pulmonary hypertension

scientific article

Riociguat dose titration in patients with chronic thromboembolic pulmonary hypertension (CTEPH) or pulmonary arterial hypertension (PAH).

scientific article

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study.

scientific article published on 7 June 2010

Riociguat for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: Results from a phase II long-term extension study.

scientific article published on 16 May 2017

Riociguat for pulmonary hypertension

scientific article published on March 2010

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension

scientific article published in July 2013

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension: a long-term extension study (CHEST-2).

scientific article

Riociguat for the treatment of pulmonary arterial hypertension

scientific article published in July 2013

Riociguat for the treatment of pulmonary arterial hypertension associated with connective tissue disease: results from PATENT-1 and PATENT-2.

scientific article published on 25 July 2016

Riociguat for the treatment of pulmonary arterial hypertension: a long-term extension study (PATENT-2).

scientific article

Riociguat for the treatment of pulmonary hypertension.

scientific article published on 11 March 2011

Riociguat for treatment of pulmonary hypertension in COPD - a translational study

scientific article published on 07 April 2019

Risk assessment in severe pulmonary hypertension due to interstitial lung disease

scientific article published on 25 June 2020

Role of Actin Depolymerization in the Surfactant Secretory Response of Alveolar Epithelial Type II Cells

scientific article published on 01 January 1999

Role of Src tyrosine kinases in experimental pulmonary hypertension

scientific article published on 19 April 2012

Role of endothelial cytoskeleton in high-permeability edema due to botulinum C2 toxin in perfused rabbit lungs

scientific article published on 01 May 1995

Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

scientific article published on 22 October 2009

Role of hypoxia-inducible factor-1alpha in hypoxia-induced apoptosis of primary alveolar epithelial type II cells

scientific journal article

Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension

scientific article published on 8 May 2008

Safety and tolerability of bosentan in idiopathic pulmonary fibrosis: an open label study

scientific article published on 10 January 2007

Schistosomiasis causes remodeling of pulmonary vessels in the lung in a heterogeneous localized manner: Detailed study

scientific article published on April 2013

Schwere Sepsis - neue Therapieverfahren

scientific article published on 01 December 2001

Selective inhibition of large-to-small surfactant aggregate conversion by serine protease inhibitors of the bis-benzamidine type

scientific article

Selexipag for the treatment of pulmonary arterial hypertension

scientific article published on 28 July 2016

Serum levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea and severe nighttime hypoxia

scientific article published in January 2002

Serum nitrite/nitrate levels in obstructive sleep apnea

scientific article published in November 2001

Severe Emphysema in the SU5416/Hypoxia Rat Model of Pulmonary Hypertension

scientific article published on 01 August 2019

Severe VA/Q mismatch in perfused lungs evoked by sequential challenge with endotoxin and E. coli hemolysin

scientific article published in March 1994

Severe organising pneumonia following COVID-19

scientific article published on 11 November 2020

Short-term "preconditioning" with inhaled nitric oxide protects rabbit lungs against ischemia-reperfusion injury.

scientific article published in October 2001

Short-term improvement in pulmonary hemodynamics is strongly predictive of long-term survival in patients with pulmonary arterial hypertension

scientific article

Short-time infusion of fish oil-based lipid emulsions, approved for parenteral nutrition, reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium in humans

scientific article published in November 2003

Sildenafil citrate therapy for pulmonary arterial hypertension

scientific article

Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension

scientific article published on 24 January 2003

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

scientific article published in September 2002

Sildenafil for treatment of severe pulmonary hypertension and commencing right-heart failure

scientific article published in November 2002

Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension

scientific article published on 23 December 2005

Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling

scientific article published in January 2008

Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial

scientific article

Sildenafil treatment for portopulmonary hypertension

scientific article

Sildenafil versus nitric oxide for acute vasodilator testing in pulmonary arterial hypertension

scientific article published on June 2015

Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.

scientific article published on August 2006

Simultaneous analysis of 4- and 5-series lipoxygenase and cytochrome P450 products from different biological sources by reversed-phase high-performance liquid chromatographic technique

scientific article

Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin

scientific article published in October 2002

Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

scientific article published on 3 June 2010

Smoking: Is it a Risk Factor for Pulmonary Vascular Diseases? ⬇️

scientific article published on October 1, 2012

Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy

scientific article published on March 2009

Soluble guanylate cyclase stimulator riociguat and phosphodiesterase 5 inhibitor sildenafil ameliorate pulmonary hypertension due to left heart disease in mice.

scientific article

Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small-Cell Lung Carcinoma

scientific article published on 22 July 2020

Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development

scientific article published on 6 March 2008

Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes

scientific article published in March 2002

Staphylococcal α-Toxin Provokes Coronary Vasoconstriction and Loss in Myocardial Contractility in Perfused Rat Hearts

scientific article published on 01 January 2000

Staphylococcus aureus alpha toxin mediates polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction

scientific article published in January 2002

Staphylococcus aureus alpha-toxin and Escherichia coli hemolysin impair cardiac regional perfusion and contractile function by activating myocardial eicosanoid metabolism in isolated rat hearts

scientific article published in June 2009

Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema

scientific article published in June 2014

Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice

scientific article published on 4 April 2014

Subhemolytic doses of Escherichia coli hemolysin evoke large quantities of lipoxygenase products in human neutrophils.

scientific article published in August 1991

Subthreshold doses of nebulized prostacyclin and rolipram synergistaically protect against lung ischemia-reperfusion

scientific article published in March 2003

Surfactant abnormalities in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and sarcoidosis

scientific article published on 01 September 1999

Surfactant alteration and replacement in acute respiratory distress syndrome

scientific article

Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema

scientific article published on 01 January 1996

Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes.

scientific article

Survival with sildenafil and inhaled iloprost in a cohort with pulmonary hypertension: an observational study.

scientific article published on 12 January 2016

Synergism between endotoxin priming and exotoxin challenge in provoking severe vascular leakage in rabbit lungs.

scientific article published in September 1997

Synergism of alveolar endotoxin "priming" and intravascular exotoxin challenge in lung injury

scientific article published in August 1996

Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply.

scientific article

Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature

scientific article

Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines.

scientific article published on 22 June 2018

Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension

scientific article published on 14 October 2020

Targeting Lipopolysaccharides by the Nontoxic Polymyxin B Nonapeptide Sensitizes ResistantEscherichia colito the Bactericidal Effect of Human Neutrophils

scientific article published on 30 June 2000

Targeting cancer with phosphodiesterase inhibitors

scientific article published on January 2010

Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension

scientific article published on 17 May 2019

Targeting non-malignant disorders with tyrosine kinase inhibitors.

scientific article published on December 2010

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats

scientific article published on 14 October 2010

The Clinical Significance of HbA1c in Operable Chronic Thromboembolic Pulmonary Hypertension.

scientific article

The Effect of Repeated Ozone Exposures on Inflammatory Markers in Bronchoalveolar Lavage Fluid and Mucosal Biopsies

scientific article published on 01 June 2000

The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups

scientific article published on 17 February 2017

The PDE inhibitor zaprinast enhances NO-mediated protection against vascular leakage in reperfused lungs

scientific article published in September 2000

The effect of 1 ppm nitrogen dioxide on bronchoalveolar lavage cells and inflammatory mediators in normal and asthmatic subjects

scientific article published on 01 March 1995

The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs

scientific article published in May 2008

The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension

scientific article

The prognostic relevance of oxygen uptake in inoperable chronic thromboembolic pulmonary hypertension

scientific article

The role of arachidonic acid metabolites in the pathogenesis of bronchial asthma

scientific article published in January 1990

The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction.

scientific article published on January 2010

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis

scientific article published on June 2011

The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis.

scientific article

The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies.

scientific article published on June 2009

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

scientific article published on 17 July 2009

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats

scientific article

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats.

scientific article

The tantalizing triplet of pulmonary hypertension-BMP receptors, serotonin receptors, and angiopoietins

scientific article

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

scientific article

Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension

scientific article

Therapie der pulmonalarteriellen Hypertonie

scientific article published on 01 September 2009

Therapie der pulmonalarteriellen Hypertonie: Phosphodiesterase-5-Inhibitoren

scientific article published in December 2006

Therapy of pulmonary arterial hypertension

scientific article published in March 2005

Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase

scientific article published on 13 July 2005

Type II alveolar epithelial eicosanoid metabolism: predominance of cyclooxygenase pathways and transcellular lipoxygenase metabolism in co-culture with neutrophils.

scientific article

Tyrosine kinase inhibitors with antiangiogenic properties for the treatment of non-small cell lung cancer.

scientific article published on 11 December 2010

Ultrasonic versus jet nebulization of iloprost in severe pulmonary hypertension

scientific article

Ultrastructural changes of lung capillary endothelium in response to botulinum C2 toxin

scientific article published in February 1997

Update in basic research in the therapy of pulmonary arterial hypertension

scientific article published on 23 September 2008

Update pulmonalarterielle Hypertonie

scientific article published on 01 September 2017

Update: Current clinical developments in pulmonary hypertension

scientific article published on 28 August 2009

Update: Preclinical developments for the treatment of pulmonary arterial hypertension

scientific article published on 28 August 2009

Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species

scientific article

Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.

scientific article

Use of fish oil to prevent graft rejection

scientific article published on 01 November 1998

Vascular Distension and Continued Ventilation Are Protective in Lung Ischemia/Reperfusion

scientific article published on 01 January 1998

Vasoregulatory prostanoid generation proceeds via cyclooxygenase-2 in noninflamed rat lungs

scientific article published on 01 September 1998

Vasotrope Therapie und Beatmung bei pulmonaler Hypertonie

scientific article published on 01 July 1999

Ventilation–Perfusion Mismatch after Lung Ischemia–Reperfusion

scientific article published on 01 October 1999

Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response

scientific article published on February 1998

Wegener's granulomatosis: antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release-role of autocrine cell activation

scientific article published in June 2002

Zardaverine and aerosolised iloprost in a model of acute respiratory failure

scientific article published in August 2003

[57] Adult respiratory distress syndrome: Model systems using isolated perfused rabbit lungs

scientific article published on 01 January 1994

[ARDS. Intensive therapy of acute lung failure]

scientific article published on 01 August 1995

[ARDS: possible role of bacterial exotoxin]

scientific article published in August 1992

[Communication center in public health]

scientific article published in June 2002

[Immunosuppressive effect of parenteral fat emulsions in defined immunostimulation]

scientific article published in April 1995

[New supportive therapy measures in acute lung failure]

scientific article published on 01 December 1995

[Prostacyclin and iloprost in aerosol form in severe pulmonary hypertension]

scientific article published on 01 January 1998

c-ANCA-induced neutrophil-mediated lung injury: a model of acute Wegener's granulomatosis

scientific article published on 23 December 2009

cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases

scientific article

cDNA array hybridization after laser-assisted microdissection from nonneoplastic tissue

scientific article

n-3 fatty acids in psoriasis

scientific article (publication date: 2002)

p38 MAPK Inhibition Improves Heart Function in Pressure Loaded Right Ventricular Hypertrophy

scientific article

sGC activators and stimulators attenuate ischemia/reperfusion injury of the lung.

scientific article

ω-3 Fatty acid–based lipid infusion in patients with chronic plaque psoriasis: Results of a double-blind, randomized, placebo-controlled, multicenter trial

scientific article published on 01 April 1998

ω-3 Lipid Infusion in a Heart Allotransplant Model

scientific article published on 01 January 1996

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