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List of works by Uri Tabori

A comprehensive review of paediatric low-grade diffuse glioma: pathology, molecular genetics and treatment

scientific article published on 25 March 2017

A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma

scientific article

Abstract NG05: TP53-mediated human cancer susceptibility is defined by epigenetic dysregulation of microRNA-34A

Advances in the management of paediatric high-grade glioma

scientific article

Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors

scientific article published on 15 October 2014

An integrative molecular and genomic analysis of pediatric hemispheric low-grade gliomas: an update

scientific article published on 20 September 2016

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

scientific article

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

scientific article published on 21 March 2018

Atypical teratoid or rhabdoid tumors: improved outcome with high-dose chemotherapy

scientific article published on July 2010

BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma

scientific article

BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma.

scientific article

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study

scientific article published on 19 May 2011

Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood

scientific article published on July 2017

Cancer Stem Cells in Prostate Cancer: Implications for Targeted Therapy

scientific article published in February 2017

Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 1.

scientific article

Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders

scientific article

Challenges in management of patients with intracranial germ cell tumor and diabetes insipidus treated with cisplatin and/or ifosfamide based chemotherapy

scientific article published on 10 October 2009

Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010.

scientific article published on 11 October 2011

Chronic residual lesions in metastatic medulloblastoma patients

scientific article published on January 2014

Clinical and treatment factors determining long-term outcomes for adult survivors of childhood low-grade glioma: A population-based study

scientific article published on 10 March 2016

Clinical implications of medulloblastoma subgroups: incidence of CSF diversion surgery

scientific article published on 19 December 2014

Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behaviour of bladder cancer

scientific article published on 30 December 2018

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

scientific article

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article published in Nature

Cytogenetic prognostication within medulloblastoma subgroups

scientific article published on 03 February 2014

DNA hypermethylation within TERT promoter upregulates TERT expression in cancer

scientific article

DNA hypermethylation within TERT promoter upregulates TERT expression in cancer

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

scientific article

Differential patterns of metastatic dissemination across medulloblastoma subgroups

scientific article published on 8 December 2017

Distinctive clinical course and pattern of relapse in adolescents with medulloblastoma

scientific article published on 28 September 2005

Divergent clonal selection dominates medulloblastoma at recurrence

scientific article published on 13 January 2016

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article (publication date: 29 January 2012)

Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent

scientific article published on 25 February 2014

EPN-38RELAPSE PATTERNS IN PEDIATRIC INTRACRANIAL EPENDYMOMA: A CANADIAN EXPERIENCE.

scientific article published on 30 May 2016

EZH2 expression is a prognostic factor in childhood intracranial ependymoma: a Canadian Pediatric Brain Tumor Consortium study

scientific article published on 13 January 2015

Early aging in adult survivors of childhood medulloblastoma: long-term neurocognitive, functional, and physical outcomes

scientific article published on 2 March 2011

Ependymoma

Ependymoma: lessons from the past, prospects for the future

scientific article

Epidermal growth factor receptor gene amplification and expression in disseminated pediatric low-grade gliomas.

scientific article published in October 2005

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

scientific article

Evolution of a T-B- SCID into an Omenn syndrome phenotype following parainfluenza 3 virus infection

scientific article

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome

scholarly article

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

scientific article published on 28 February 2018

Favorable outcome with conservative treatment for children with low grade brainstem tumors

scientific article published on 25 May 2011

Favorable survival and metabolic outcome for children with diencephalic syndrome using a radiation-sparing approach

scientific article published on 12 November 2013

Feasibility and efficacy of repeated chemotherapy for progressive pediatric low-grade gliomas

scientific article published in December 2010

Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation

scientific article published on 17 July 2013

Gastrointestinal Findings in the Largest Series of Patients With Hereditary Biallelic Mismatch Repair Deficiency Syndrome: Report from the International Consortium

scientific article published on 5 January 2016

Gender as a disease modifier in neurofibromatosis type 1 optic pathway glioma

scientific article published on 14 May 2014

Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas

scientific article published on 24 May 2011

Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium.

scientific article published on 15 January 2014

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

scientific article

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

scientific article (publication date: May 2014)

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

scientific article published on 30 April 2013

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

scientific article published on 06 January 2022

HG-80ISSUES IN THE MANAGEMENT OF CHILDREN WITH BRAIN TUMORS AND BIALLELIC MISMATCH GENE REPAIR DEFICIENCY SYNDROME.

scientific article published on 30 May 2016

HGG-18. GLIOMAS IN ADOLESCENTS AND YOUNG ADULTS SHARE SEVERAL MOLECULAR FEATURES WITH THEIR PEDIATRIC COUNTERPARTS.

scientific article published on 31 May 2017

Hearing Loss After Radiation and Chemotherapy for CNS and Head-and-Neck Tumors in Children

scientific article published in 2021

Heterogeneity within the PF-EPN-B ependymoma subgroup

article

High frequency of mismatch repair deficiency among pediatric high grade gliomas in Jordan

scientific article published on 8 August 2015

Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma

scientific article

Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.

scientific article

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

scientific article

Intertumoral Heterogeneity within Medulloblastoma Subgroups

scientific article published on June 2017

Isolated optic nerve gliomas: a multicenter historical cohort study

scientific article published on 6 October 2017

LG-02MYB-QKI REARRANGEMENTS IN ANGIOCENTRIC GLIOMA DRIVE TUMORIGENICITY THROUGH A TRIPARTITE MECHANISM.

scientific article published on 30 May 2016

LG-19IMMUNOHISTOCHEMISTRY IS HIGHLY SENSITIVE AND SPECIFIC FOR THE DETECTION OF BRAF V600E STATUS IN PEDIATRIC LOW-GRADE GLIOMA.

scientific article published on 30 May 2016

LG-50MULTIPLEX DETECTION OF PEDIATRIC LOW GRADE GLIOMA SIGNATURE FUSION AND DUPLICATION TRANSCRIPTS USING THE NANOSTRING NCOUNTER SYSTEM.

scientific article published on 30 May 2016

LGG-10. EPIGENETIC/GENETIC/MORPHOLOGIC ANALYSES REVEAL CLINICAL/PROGNOSTIC INSIGHT OF PEDIATRIC LOW GRADE GLIOMAS

LGG-16. LOCATION AND HISTOLOGY DICTATE THE LIKELIHOOD OF MOLECULAR EVENTS IN PEDIATRIC LOW-GRADE GLIOMA.

scientific article

LGG-18. MOLECULAR ALTERATIONS PREDICT RESPONSE TO CHEMOTHERAPY AND OUTCOME OF PEDIATRIC LOW-GRADE GLIOMA.

scientific article published on 31 May 2017

Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium

scientific article published on 29 August 2012

Low prevalence of complications in severe neutropenic children with cancer in the unprotected environment of an overnight camp

scientific article

MB-53hTERT EXPRESSION AND REGULATION IN PEDIATRIC MEDULLOBLASTOMA (MB).

scientific article published on 30 May 2016

MEDU-34. INTELLECTUAL OUTCOME IN CHILDREN WITH SENSORINEURAL HEARING LOSS FOLLOWING TREATMENT FOR EMBRYONAL BRAIN TUMORS.

scientific article

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

scientific article

Management of Acute Myeloblastic Leukemia in a Child With Biallelic Mismatch Repair Deficiency

scientific article published on 12 August 2015

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer

scientific article published on 12 March 2018

Medulloblastoma in the second decade of life: a specific group with respect to toxicity and management: a Canadian Pediatric Brain Tumor Consortium Study

scientific article

Medulloblastoma subgroup-specific outcomes in irradiated children: who are the true high-risk patients?

scientific article

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.

scientific article

Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups

scientific article published on 21 October 2014

Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors

scientific article published on 5 December 2011

Multiple Brain Developmental Venous Anomalies as a Marker for Constitutional Mismatch Repair Deficiency Syndrome

scientific article published on 30 August 2018

Multiplex Detection of Pediatric Low-Grade Glioma Signature Fusion Transcripts and Duplications Using the NanoString nCounter System

scientific article published in July 2017

Natural history and outcome of optic pathway gliomas in children

scientific article published on December 2009

Neoadjuvant chemotherapy reduces blood loss during the resection of pediatric choroid plexus carcinomas

scientific article published on May 2015

Neural correlates of delayed visual-motor performance in children treated for brain tumours

scientific article published on 20 September 2012

Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition

scientific article published in January 2011

No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients

scientific article published on 11 March 2016

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age.

scientific article published on 10 September 2015

Oncologic surveillance for subjects with biallelic mismatch repair gene mutations-10 year follow-up in a kindred

scientific article published on 10 March 2011

Oncologic surveillance for subjects with biallelic mismatch repair gene mutations: 10 year follow-up of a kindred

scientific article

Optic pathway gliomas in adolescence--time to challenge treatment choices?

scientific article published on 7 January 2013

Optic pathway gliomas: a review.

scientific article

Outcome of secondary high-grade glioma in children previously treated for a malignant condition: a study of the Canadian Pediatric Brain Tumour Consortium

scientific article published on 14 September 2006

PT-01THE IMPACT OF INITIAL RADIATION IN INFANTS AND THE RE-IRRADIATION OF RECURRENT DISEASE ON THE SURVIVAL OF EPENDYMOMA PATIENTS AT THE HOSPITAL FOR SICK CHILDREN, TORONTO.

scientific article published in November 2014

Paediatric ependymomas: should we avoid radiotherapy?

scientific article

Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma

scientific article published on 01 June 2020

Pediatric High Grade Gliomas in the Context of Cancer Predisposition Syndromes.

scientific article published in May 2018

Pediatric Low-Grade Gliomas: Next Biologically Driven Steps

scientific article published on 2 August 2017

Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study

scientific article

Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma

scientific article published on 5 March 2012

Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome

scientific article published on 13 April 2015

Possibilities of new therapeutic strategies in brain tumors

scientific article published on 25 February 2010

Primary Ewing's sarcoma affecting the central nervous system: a review and proposed prognostic considerations

scientific article published on 22 October 2011

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis

scientific article published on 20 November 2020

Profound clinical and radiological response to BRAF inhibition in a 2-month-old diencephalic child with hypothalamic/chiasmatic glioma

scientific article published on 11 July 2016

Prognostic relevance of miR-124-3p and its target TP53INP1 in pediatric ependymoma

scientific article published on 24 April 2017

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

scientific article published on 11 March 2016

Promises and challenges of exhausting pediatric neural cancer stem cells

scientific article published on 08 February 2012

Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors

scientific article published on March 2010

Rare Presentation of Supratentorial Primitive Neuroectodermal Tumors Mimicking Bifocal Germ Cell Tumors: 2 Case Reports.

scientific article published in August 2015

Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

scientific article published on 17 October 2013

Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour

scientific article published on 9 June 2014

Reirradiation in patients with diffuse intrinsic pontine gliomas: The Canadian experience

scientific article

Reply to D.T.W. Jones et al.

scientific article published on 15 November 2017

Reply to J.C. Lindsey et al

Response to Immune Checkpoint Inhibition in Two Patients with Alveolar Soft-Part Sarcoma

scientific article published on 17 July 2018

Risk of venous thromboembolism in pediatric patients with brain tumors.

scientific article

Risk stratification in cancer predisposition syndromes: lessons learned from novel molecular developments in Li-Fraumeni syndrome

scientific article published on April 2008

Spatial heterogeneity in medulloblastoma

scientific article published on 10 April 2017

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma

scientific article published on 08 July 2013

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article

Successful treatment of a recurrent choroid plexus carcinoma with surgery followed by high-dose chemotherapy and stem cell rescue.

scientific article published on 9 January 2013

Survival and functional outcome of childhood spinal cord low-grade gliomas. Clinical article

scientific article published in September 2009

Survival benefit for pediatric patients with recurrent ependymoma treated with reirradiation

scientific article published on 13 January 2012

Sustained Response to Targeted Therapy in a Patient With Disseminated Anaplastic Pleomorphic Xanthoastrocytoma

scientific article published in December 2017

Synchronous glioblastoma and medulloblastoma in a child with mismatch repair mutation

scientific article published on 21 August 2015

Syndromes predisposing to pediatric central nervous system tumors: lessons learned and new promises

scientific article

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

scientific article published on 31 October 2013

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors

scientific article published on 22 March 2010

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

scientific article

Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

scientific article published on 31 August 2016

Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells

scientific article

Telomerase inhibition as a novel therapy for pediatric ependymoma

scientific article

Telomere biology of pediatric cancer

scientific article published on April 2007

Telomere dysfunction and chromothripsis

scientific article published on 9 February 2016

The Changing Landscape of Pediatric Low-Grade Gliomas: Clinical Challenges and Emerging Therapies

scientific article

The TERT hypermethylated oncologic region predicts recurrence and survival in pancreatic cancer

scientific article

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

scientific article

The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience

scientific article

The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas

scientific article published in February 2006

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

scientific article published on 06 June 2016

Translational Childhood Cancer Genomics: The Future Is Now.

scientific article

Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations

scientific article published on 8 February 2010

Use of ifosfamide, carboplatin, and etoposide chemotherapy in choroid plexus carcinoma

scientific article published on June 2010

Vincristine and carboplatin chemotherapy for unresectable and/or recurrent low-grade astrocytoma of the brainstem

scientific article published on September 2010

Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis

scientific article

Volumetric assessment of tumor size changes in pediatric low-grade gliomas: feasibility and comparison with linear measurements

scientific article published on 30 January 2018

WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma

scientific article

Weekly vinblastine in pediatric low-grade glioma patients with carboplatin allergic reaction.

scientific article published in June 2005

When Parallel Roads Meet: Orchestrating Collaborations Between Regulatory, Ethical, and Business Partners in Translational Medicine

scientific article published on 03 May 2019

White matter compromise predicts poor intellectual outcome in survivors of pediatric low-grade glioma

scientific article published on 13 November 2014

Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome.

scientific article published in February 2007

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