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List of works by Werner Weitschies

A Semi-mechanistic Modeling Strategy for Characterization of Regional Absorption Properties and Prospective Prediction of Plasma Concentrations Following Administration of New Modified Release Formulations

scientific article published on 23 September 2011

A Semi-mechanistic Modeling Strategy to Link In Vitro and In Vivo Drug Release for Modified Release Formulations

scientific article published on 27 September 2011

A biorelevant dissolution stress test device - background and experiences.

scientific article

A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations

scientific article published on 08 March 2012

Advances in coronary stent technology--active drug-loaded stent surfaces for prevention of restenosis and improvement of biocompatibility.

scientific article published on January 2013

An Advanced Bioreactor Simulating Dynamic Physiological Conditions in the Human Ascending Colon: MimiCol<sup>3</sup>

scientific article published on 13 May 2022

An International Network for Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process

article

An automated system for monitoring and regulating the pH of bicarbonate buffers

scientific article published on 7 March 2013

An oral-controlled release drug delivery system for liquid and semisolid drug formulations.

scientific article published on 15 September 2011

Application of an automated small-scale in vitro transfer model to predict in vivo precipitation inhibition

scientific article published on 11 May 2019

Application of the GastroDuo as an in Vitro Dissolution Tool To Simulate the Gastric Emptying of the Postprandial Stomach

scientific article published on 22 October 2019

Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy

scientific article published on 20 January 2009

Automated small-scale in vitro transfer model as screening tool for the prediction of in vivo-dissolution and precipitation of poorly solubles

scientific article published on 12 December 2018

Bioavailability of amoxicillin and clavulanic acid from extended release tablets depends on intragastric tablet deposition and gastric emptying.

scientific article published on 5 June 2008

CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.

scientific article

Changes in recovery due to drug product matrix ageing as a source of mass imbalances

scientific article published on 22 October 2012

Characterization of the behavior of alginate-based microcapsules in vitro and in vivo.

scientific article published in September 2009

Characterization of the gastrointestinal transit and disintegration behavior of floating and sinking acid-resistant capsules using a novel MRI labeling technique

scientific article published on 10 January 2019

Close approximation of two platelet factor 4 tetramers by charge neutralization forms the antigens recognized by HIT antibodies

scientific article

Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects

scientific article published on 08 March 2019

Comparison of In Vitro and In Vivo Results Using the GastroDuo and the Salivary Tracer Technique: Immediate Release Dosage Forms under Fasting Conditions

scientific article published on 07 December 2019

Comparison of dissolution profiles obtained from nifedipine extended release once a day products using different dissolution test apparatuses.

scientific article published on 8 July 2009

Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals

scientific article

Design and characterization of a novel 3D printed pressure-controlled drug delivery system

scientific article published on 06 September 2019

Design of biorelevant test setups for the prediction of diclofenac in vivo features after oral administration

scientific article published on 30 March 2013

Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry

scientific article published on 17 October 2003

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

scientific article published on 30 May 2012

Determination of the disintegration behavior of magnetically marked tablets

scientific article published on 01 September 2001

Determination of the magneto-optical relaxation of magnetic nanoparticles as a homogeneous immunoassay

scientific article published in January 2007

Development of a dual extrusion printing technique for an acid- and thermo-labile drug

article

Development of a method for magnetic labeling of platelets

scientific article published on 22 October 2011

Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents

scientific article published on 19 May 2008

Development of an oral vaccine for immunisation of rainbow trout (Oncorhynchus mykiss) against viral haemorrhagic septicaemia.

scientific article

Development of hydrophobized alginate hydrogels for the vessel-simulating flow-through cell and their usage for biorelevant drug-eluting stent testing.

scientific article published on 6 August 2013

Development of oral taste masked diclofenac formulations using a taste sensing system.

scientific article published on 7 September 2012

Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells

scientific article published on 24 January 2006

Direct visualization and identification of biofunctionalized nanoparticles using a magnetic atomic force microscope.

scientific article

Disposition and antimuscarinic effects of the urinary bladder spasmolytics propiverine: influence of dosage forms and circadian-time rhythms.

scientific article

Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins

scientific article published on 01 November 2006

Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats

scientific article published on 13 June 2006

Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers.

scientific article published on 2 March 2011

Effect of Coadministered Water on the In Vivo Performance of Oral Formulations Containing N-Acetylcysteine: An In Vitro Approach Using the Dynamic Open Flow-Through Test Apparatus

scientific article published on 24 October 2017

Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro

scientific article published on 8 January 2011

Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes.

scientific article published on 13 July 2010

Esophageal transit of solid drug forms depends on body position, swallowing volume and pharyngeal propulsion velocity — a magnetic marker monitoring (MMM) study

Evaluation of consultation in community pharmacies with mystery shoppers

scientific article published on 22 May 2007

Examination of drug release and distribution from drug-eluting stents with a vessel-simulating flow-through cell

scientific article

Examination of steroid release from screw-in pacing leads

scientific article published on 06 September 2012

Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

scientific article published on 17 July 2020

Foreword for the JPP special issue 'Recent innovations in dissolution testing'

scientific article published on 01 July 2012

Gastric Emptying and Small Bowel Water Content after Administration of Grapefruit Juice Compared to Water and Isocaloric Solutions of Glucose and Fructose: A Four-Way Crossover MRI Pilot Study in Healthy Subjects

scientific article published on 3 January 2018

Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions.

scientific article published on 20 September 2017

Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes

scientific article

Heparin-induced thrombocytopenia: a stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings

scientific article

Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

scientific article published on 20 April 2010

High-resolution monitoring of the gastrointestinal transit of a magnetically marked capsule

scientific article published on 01 November 1997

Impact of the intragastric location of extended release tablets on food interactions

scientific article

Improved Prediction of in Vivo Supersaturation and Precipitation of Poorly Soluble Weakly Basic Drugs Using a Biorelevant Bicarbonate Buffer in a Gastrointestinal Transfer Model

scientific article published on 07 August 2019

In vitro dissolution testing of drug-eluting stents.

scientific article published on January 2013

In vitro simulation of realistic gastric pressure profiles.

scientific article

In vivo imaging of drug delivery systems in the gastrointestinal tract.

scientific article published on 26 July 2011

In-line derivative spectroscopy as a promising application to a small-scale in vitro transfer model in biorelevant supersaturation and precipitation testing

scientific article published on 30 July 2018

In-vitro dissolution methods for controlled release parenterals and their applicability to drug-eluting stent testing.

scientific article published on 07 February 2012

Individualized, Additively Manufactured Drug-Releasing External Ear Canal Implant for Prevention of Postoperative Restenosis: Development, In Vitro Testing, and Proof of Concept in an Individual Curative Trial

scientific article published in 2022

Influence of the test method on in vitro drug release from intravitreal model implants containing dexamethasone or fluorescein sodium in poly (d,l-lactide-co-glycolide) or polycaprolactone

scientific article

Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetim

scientific article published on 7 February 2006

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.

scientific article published on 6 January 2011

Investigation of gastrointestinal transport by magnetic marker localization

scientific article published in January 2002

Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses

scientific article published on 7 June 2008

Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro

scientific article

Magnetic marker monitoring of disintegrating capsules.

scientific article published in July 2001

Magnetic marker monitoring of esophageal, gastric and duodenal transit of non-disintegrating capsules

scientific article published in June 1999

Magnetic marker monitoring: high resolution real-time tracking of oral solid dosage forms in the gastrointestinal tract.

scientific article published on 18 July 2009

Magnetic markers as a noninvasive tool to monitor gastrointestinal transit

scientific article published in February 1994

Magnetic markers in the gastrointestinal tract--a new method for the study of absorption of solid oral drugs

scientific article published on 01 January 1990

Magneto-Optical Relaxation Measurements of Functionalized Nanoparticles as a Novel Biosensor ⬇️

scientific article published on May 26, 2009

Magnetorelaxometry—a new binding specific detection method based on magnetic nanoparticles

article published in 2002

Mechanistic modeling of a magnetic marker monitoring study linking gastrointestinal tablet transit, in vivo drug release, and pharmacokinetics.

scientific article

N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes

scientific article published on 15 June 2010

Nanoparticle Composition of a Ferrofluid and Its Effects on the Magnetic Properties

article

Oesophageal transport of solid dosage forms depends on body position, swallowing volume and pharyngeal propulsion velocity

scientific article published in October 2004

Preparation and characterization of magnetizable aerosols.

scientific article

Response

Separation of delta6- and delta9,11-estradiol: analytical method development, validation and practical application

scientific article published in May 2013

Significance of drug transporter for the internal medicine clinic

scientific article

Simulating the Postprandial Stomach: Physiological Considerations for Dissolution and Release Testing ⬇️

scientific article published on May 6, 2013

Simulating the postprandial stomach: biorelevant test methods for the estimation of intragastric drug dissolution.

scientific article published on 08 May 2013

Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector

scientific article published on 01 September 2011

The Vitreous Model - a new in vitro test method simulating the vitreous body

scientific article published on 06 September 2012

The role of individual gastric emptying of pellets in the prediction of diclofenac in vivo dissolution.

scientific article

The talinolol double-peak phenomenon is likely caused by presystemic processing after uptake from gut lumen

scientific article published on 17 May 2005

Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets

scientific article published in March 2003

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging

scientific article published on 06 July 2012

[Magnets instead of radioisotope: pills in the gastrointestinal tract]

scientific article published on 01 March 2000

[The challenge of patient consultation and pharmaceutical development: bisphosphonate in solid dosage forms]

scientific article published on 01 January 2001

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