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List of works by William Trigg

(99m)Tc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation

scientific article published on March 2015

18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke.

scientific article published on 29 October 2014

Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats

scientific article published on August 2016

Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180.

scientific article published on 10 February 2014

Dynamic TSPO-PET for assessing early effects of cerebral hypoxia and resuscitation in new born pigs

scientific article published on 24 August 2018

Evaluation of a novel series of fluorine-18-labeled imidazobenzodiazepines as potential new positron emission tomography radioligands for the GABAA receptor.

scientific article published on 7 December 2013

Ex Vivo Tracing of NMDA and GABA-A Receptors in Rat Brain After Traumatic Brain Injury Using 18F-GE-179 and 18F-GE-194 Autoradiography

scientific article

Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.

scientific article published on 27 May 2015

Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents.

scientific article

Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents

scientific article published on 3 August 2012

Flutriciclamide (18F-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.

scientific article published on 3 June 2016

Gd3+ cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation

scientific article published on 4 December 2012

In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.

scientific article

In vivo PET imaging demonstrates diminished microglial activation after fingolimod treatment in an animal model of multiple sclerosis

scientific article published on 08 January 2015

In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acid

scientific article published on 07 May 2016

Initial evaluation of 18F-GE-179, a putative PET Tracer for activated N-methyl D-aspartate receptors

scientific article published on 13 February 2014

Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain

scientific article published on 28 June 2016

NMDA receptor binding in focal epilepsies

scientific article

Novel fluorine-18 PET radiotracers based on flumazenil for GABAA imaging in the brain.

scientific article published on 23 July 2013

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO).

scientific article published on 22 May 2018

Radiosynthesis of (R,S)-[18 F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971.

scientific article published on 8 April 2019

Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

scientific article

Space-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice

scientific article published on 20 August 2019

The development of an automated and GMP compliant FASTlab™ Synthesis of [(18) F]GE-180; a radiotracer for imaging translocator protein (TSPO).

scientific article

The development of potential new fluorine-18 labelled radiotracers for imaging the GABA(A) receptor.

scientific article

[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease

scientific article published on 24 March 2017

[¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO).

scientific article published on 27 December 2011