List of works - Hein J Wijma

A conserved sequence motif in the Escherichia coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency

scientific article published in 2022

A random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase

scientific article

A rearranging ligand enables allosteric control of catalytic activity in copper-containing nitrite reductase.

scientific article published on 6 March 2006

A robust cosolvent-compatible halohydrin dehalogenase by computational library design.

scientific article

Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum

scientific article published on 18 February 2011

Bidirectional catalysis by copper-containing nitrite reductase.

scientific article published in August 2004

Biochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxus

scientific article

Calorimetric and spectroscopic investigations of the thermal denaturation of wild type nitrite reductase

scientific article published on 01 August 2005

Computational Design of Enantiocomplementary Epoxide Hydrolases for Asymmetric Synthesis of Aliphatic and Aromatic Diols

scientific article published on 21 January 2020

Computational Redesign of an ω-Transaminase from <i>Pseudomonas jessenii</i> for Asymmetric Synthesis of Enantiopure Bulky Amines

scientific article published on 13 August 2021

Computational library design for increasing haloalkane dehalogenase stability

scientific article

Computational redesign of enzymes for regio- and enantioselective hydroamination

scientific article published on 21 May 2018

Computationally designed libraries for rapid enzyme stabilization

scientific article

Computationally efficient and accurate enantioselectivity modeling by clusters of molecular dynamics simulations

scientific article published on 30 June 2014

Effect of the methionine ligand on the reorganization energy of the type-1 copper site of nitrite reductase

scientific article

Enantioselective enzymes by computational design and in silico screening

scientific article published on 4 February 2015

Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase

scientific article published on 5 October 2010

Exploring the gating mechanisms of aquaporin-3: new clues for the design of inhibitors?

scientific article published on 10 March 2016

Hot or not? Discovery and characterization of a thermostable alditol oxidase from Acidothermus cellulolyticus 11B.

scientific article

Metabolism of β-valine via a CoA-dependent ammonia lyase pathway

scientific article published on 26 May 2015

Protein Film Voltammetry of Copper-Containing Nitrite Reductase Reveals Reversible Inactivation

scholarly article by Hein J Wijma et al published July 2007 in Journal of the American Chemical Society

Reconstitution of the type-1 active site of the H145G/A variants of nitrite reductase by ligand insertion

scientific article (publication date: 15 April 2003)

Sensing nitrite through a pseudoazurin-nitrite reductase electron transfer relay

scientific article published in June 2005

Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue

scientific article

Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability.

scientific article published on 15 May 2013

The substrate-bound type 2 copper site of nitrite reductase: the nitrogen hyperfine coupling of nitrite revealed by pulsed EPR.

scientific article

Thermal stability effects of removing the type-2 copper ligand His306 at the interface of nitrite reductase subunits

scientific article published on 16 March 2007

X-ray crystallographic validation of structure predictions used in computational design for protein stabilization

scientific article

List of works by Hein J Wijma

A conserved sequence motif in the Escherichia coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency

A random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase

A rearranging ligand enables allosteric control of catalytic activity in copper-containing nitrite reductase.

A robust cosolvent-compatible halohydrin dehalogenase by computational library design.

Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum

Bidirectional catalysis by copper-containing nitrite reductase.

Biochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxus

Calorimetric and spectroscopic investigations of the thermal denaturation of wild type nitrite reductase

Computational Design of Enantiocomplementary Epoxide Hydrolases for Asymmetric Synthesis of Aliphatic and Aromatic Diols

Computational Redesign of an ω-Transaminase from <i>Pseudomonas jessenii</i> for Asymmetric Synthesis of Enantiopure Bulky Amines

Computational library design for increasing haloalkane dehalogenase stability

Computational redesign of enzymes for regio- and enantioselective hydroamination

Computationally designed libraries for rapid enzyme stabilization

Computationally efficient and accurate enantioselectivity modeling by clusters of molecular dynamics simulations

Effect of the methionine ligand on the reorganization energy of the type-1 copper site of nitrite reductase

Enantioselective enzymes by computational design and in silico screening

Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase

Exploring the gating mechanisms of aquaporin-3: new clues for the design of inhibitors?

Hot or not? Discovery and characterization of a thermostable alditol oxidase from Acidothermus cellulolyticus 11B.

Metabolism of β-valine via a CoA-dependent ammonia lyase pathway

Protein Film Voltammetry of Copper-Containing Nitrite Reductase Reveals Reversible Inactivation

Reconstitution of the type-1 active site of the H145G/A variants of nitrite reductase by ligand insertion

Sensing nitrite through a pseudoazurin-nitrite reductase electron transfer relay

Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue

Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability.

The substrate-bound type 2 copper site of nitrite reductase: the nitrogen hyperfine coupling of nitrite revealed by pulsed EPR.

Thermal stability effects of removing the type-2 copper ligand His306 at the interface of nitrite reductase subunits

X-ray crystallographic validation of structure predictions used in computational design for protein stabilization