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List of works by Jader Santos Cruz

(-)-Terpinen-4-ol changes intracellular Ca2+ handling and induces pacing disturbance in rat hearts.

scientific article published on 20 April 2017

(S)-reticuline induces vasorelaxation through the blockade of L-type Ca(2+) channels.

scientific article published on 30 September 2008

A toxin from the spider Phoneutria nigriventer that blocks calcium channels coupled to exocytosis

scientific article

Abolition of reperfusion-induced arrhythmias in hearts from thiamine-deficient rats

scientific article published on 16 March 2007

Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats

scientific article

Altered Cardiomyocyte Function and Trypanosoma cruzi Persistence in Chagas Disease.

scientific article published on 14 March 2016

Angiotensin II increases excitability and inhibits a transient potassium current in vagal primary sensory neurons.

scientific article published on 9 May 2009

Aqueous fraction from Costus spiralis (Jacq.) Roscoe leaf reduces contractility by impairing the calcium inward current in the mammalian myocardium.

scientific article published on 22 September 2011

Basal and β-adrenergic cardiomyocytes contractility dysfunction induced by dietary protein restriction is associated with downregulation of SERCA2a expression and disturbance of endoplasmic reticulum Ca2+ regulation in rats.

scientific article published on 30 July 2014

CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons.

scientific article published on 4 April 2007

Calcium channel blockade as a target for the cardiovascular effects induced by the 8 (17), 12E, 14-labdatrien-18-oic acid (labdane-302)

scientific article published on 09 March 2006

Cardiac oxidative stress is involved in heart failure induced by thiamine deprivation in rats.

scientific article published on 19 March 2010

Cardiac structural changes and electrical remodeling in a thiamine-deficiency model in rats

scientific article

Cardiodepressive effect elicited by the essential oil of Alpinia speciosa is related to L-type Ca²+ current blockade

scientific article published on 26 November 2010

Cardiotoxic effects of Loxosceles intermedia spider venom and the recombinant venom toxin rLiD1.

scientific article

Cardiovascular effects of Sp-CTx, a cytolysin from the scorpionfish (Scorpaena plumieri) venom.

scientific article published on 4 May 2016

Carvacrol modulates voltage-gated sodium channels kinetics in dorsal root ganglia

scientific article published on 17 March 2015

Changes in cellular contractility and cytokines profile during Trypanosoma cruzi infection in mice

scientific article published on 3 February 2009

Chronic exercise partially restores the transmural heterogeneity of action potential duration in left ventricular myocytes of spontaneous hypertensive rats.

scientific article published in February 2012

Cloning of cDNAS encoding neurotoxic peptides from the spider Phoneutria nigriventer.

scientific article

Croton sonderianus essential oil samples distinctly affect rat airway smooth muscle.

scientific article published on 19 February 2010

Current aspects of thiamine deficiency on heart function.

scientific article published on 04 January 2014

Depressive effects of arenobufagin on the delayed rectifier K+ current of guinea-pig cardiac myocytes

scientific article published on 01 February 1994

Detection of oral streptococci in dental biofilm from caries-active and caries-free children.

scientific article published on October 2008

Dissection of the Effects of Quercetin on Mouse Myocardium.

scientific article published on 19 December 2016

Distinct effects of carvone analogues on the isolated nerve of rats.

scientific article published on 27 July 2010

Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure

scientific article

Electrical properties of isolated cardiomyocytes in a rat model of thiamine deficiency.

scientific article published on March 2015

Electrophysiological characterization and molecular identification of the Phoneutria nigriventer peptide toxin PnTx2-6.

scientific article

Essential oils components as a new path to understand ion channel molecular pharmacology.

scientific article published on 19 May 2011

Evaluation of the sesquiterpene (-)-alpha-bisabolol as a novel peripheral nervous blocker.

scientific article published on 25 January 2010

Exercise Training Protects Cardiomyocytes from Deleterious Effects of Palmitate.

scientific article

Exercise capacity is related to calcium transients in ventricular cardiomyocytes.

scientific article published on 4 June 2009

Functionalized nanomaterials: are they effective to perform gene delivery to difficult-to-transfect cells with no cytotoxicity?

scientific article published on 21 October 2015

Glutamate transport in rat cerebellar granule cells is impaired by inorganic epileptogenic agents

scientific article

Hydroalcoholic extract from Nerium oleander L. (Apocynaceae) elicits arrhythmogenic activity.

scientific article published on 28 May 2017

Impaired cellular contractile function in thiamine-deficient rat cardiomyocytes.

scientific article published on 29 October 2009

Impairment of In Vitro and In Vivo Heart Function in Angiotensin-(1-7) Receptor Mas Knockout Mice

scientific article published on 27 March 2006

Inhibition of neuronal high-voltage activated calcium channels by the omega-phoneutria nigriventer Tx3-3 peptide toxin.

scientific article published in July 2000

Inhibitory effect of terpinen-4-ol on voltage-dependent potassium currents in rat small sensory neurons.

scientific article

Investigation of terpinen-4-ol effects on vascular smooth muscle relaxation

scientific article published on 16 September 2014

Investigation of the cardiomyocyte dysfunction in bradykinin type 2 receptor knockout mice

scientific article published on 21 October 2010

Is there a role for voltage-gated Na+ channels in the aggressiveness of breast cancer?

scientific article

Kinin B1 receptor participates in the control of cardiac function in mice

article

Leftward shift in the voltage-dependence for Ca2+ currents activation induced by a new toxin from Phoneutria reidyi (Aranae, Ctenidae) venom.

scientific article published on 7 December 2006

Linalool blocks excitability in peripheral nerves and voltage-dependent Na+ current in dissociated dorsal root ganglia neurons.

scientific article published on 22 July 2010

Macrophage damage by Leishmania amazonensis cytolysin: evidence of pore formation on cell membrane

scientific article published in August 2000

Mechanism of the antihypertensive and vasorelaxant effects of the flavonoid tiliroside in resistance arteries

scientific article published on 22 July 2013

Mechanisms of vascular dysfunction in acute phase of Trypanosoma cruzi infection in mice.

scientific article published on 14 March 2016

Molecular and biochemical characterization of a cytolysin from the Scorpaena plumieri (scorpionfish) venom: evidence of pore formation on erythrocyte cell membrane

scientific article published on 8 August 2013

Molecular mechanisms of cardiac electromechanical remodeling during Chagas disease: Role of TNF and TGF-β.

scientific article published on 11 August 2016

Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway

scientific article

Morphology and contractility in cardiomyocytes of rats with low exercise performance.

scientific article published on 12 April 2012

N-salicyloyltryptamine, a new anticonvulsant drug, acts on voltage-dependent Na+, Ca2+, and K+ ion channels.

scientific article published on December 2003

N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease

scientific article published on 18 March 2017

New insights into the elucidation of angiotensin-(1-7) in vivo antiarrhythmic effects and its related cellular mechanisms

scientific article

Novel insights into the development of chagasic cardiomyopathy: role of PI3Kinase/NO axis.

scientific article published on 29 September 2012

PhTx4, a new class of toxins from Phoneutria nigriventer spider venom, inhibits the glutamate uptake in rat brain synaptosomes

scientific article

Pharmacological evaluation of R(+)-pulegone on cardiac excitability: Role of potassium current blockage and control of action potential waveform

scientific article published in September 2014

Phoneutria nigriventer toxin Tx3-1 blocks A-type K+ currents controlling Ca2+ oscillation frequency in GH3 cells.

scientific article

Phosphatidylinositol 3‐kinase‐δ up‐regulates L‐type Ca2+ currents and increases vascular contractility in a mouse model of type 1 diabetes ⬇️

scientific article published on December 1, 2010

Plasma cytokine response, lipid peroxidation and NF-kB activation in skeletal muscle following maximum progressive swimming.

scientific article published on 20 April 2011

PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP.

scientific article

Probabilistic model checking analysis of palytoxin effects on cell energy reactions of the Na+/K+-ATPase

scientific article published in November 2013

R(+)-pulegone impairs Ca²+ homeostasis and causes negative inotropism in mammalian myocardium

article

Regional effects of low-intensity endurance training on structural and mechanical properties of rat ventricular myocytes

scientific article published on 2 May 2013

Regulation of the glutamate uptake by extracellular calcium.

scientific article published in May 2002

Resident Macrophages Orchestrating Heart Rate.

scientific article

Resurgent Na+ current: A new avenue to neuronal excitability control ⬇️

scientific article published on June 13, 2011

Role of SOCS2 in modulating heart damage and function in a murine model of acute Chagas disease.

scientific article published on 29 May 2012

Rosewood oil induces sedation and inhibits compound action potential in rodents

scientific article (publication date: 30 July 2009)

Rotundifolone-induced relaxation is mediated by BK(Ca) channel activation and Ca(v) channel inactivation

scientific article published on 08 August 2011

Structure and activity analysis of two spider toxins that alter sodium channel inactivation kinetics.

scientific article published in April 2009

Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents

scientific article published on 02 May 2006

Swim training does not protect mice from skeletal muscle oxidative damage following a maximum exercise test

scientific article published on 11 November 2011

TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation

scientific article published on 23 November 2015

Tension generation and increase in voltage-activated Na+ current by crotamine

scientific article published in May 1998

The benefits of endurance training in cardiomyocyte function in hypertensive rats are reversed within four weeks of detraining

scientific article published on 30 January 2013

The endocannabinoid system mediates aerobic exercise-induced antinociception in rats.

scientific article published on 19 October 2013

The positive inotropic effect of the ethyl acetate fraction from Erythrina velutina leaves on the mammalian myocardium: the role of adrenergic receptors

scientific article published on 10 April 2013

Thiamine Deficiency Increases Ca2+ Current and CaV1.2 L-type Ca2+ Channel Levels in Cerebellum Granular Neurons

scientific article

Thiamine deficiency in vitro accelerates A-type potassium current inactivation in cerebellar granule neurons

scientific article published on 4 July 2012

Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats.

scientific article published on 6 October 2013

Tityustoxin effect on nerve compound action potentials requires extracellular sodium

scientific article published on 01 March 2000

Vascular Kinin B1 and B2 Receptors Determine Endothelial Dysfunction through Neuronal Nitric Oxide Synthase.

scientific article published on 28 April 2017

Veratridine modifies the TTX-resistant Na+ channels in rat vagal afferent neurons

scientific article published in March 2004

Warifteine, a bisbenzylisoquinoline alkaloid, induces relaxation by activating potassium channels in vascular myocytes

scientific article published on 01 January 2013

trans-Caryophyllene, a Natural Sesquiterpene, Causes Tracheal Smooth Muscle Relaxation through Blockade of Voltage-Dependent Ca2+ Channels ⬇️

scientific article published on October 11, 2012

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