List of works - Colin A Purdie

17q allele loss is associated with lymph node metastasis in locally aggressive human colorectal cancer

A candidate molecular signature associated with tamoxifen failure in primary breast cancer

scientific article published on 17 October 2008

A comparison of the imaging features of pleomorphic and classical invasive lobular carcinoma

scientific article published on 09 August 2018

A feasibility study of soft embalmed human breast tissue for preclinical trials of HIFU- preliminary results

A prognostic index for operable, node-negative breast cancer.

scientific article published on May 2004

A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer

scientific article

A simple and rapid approach to the problem of tissue contamination and patient identity in histopathologic specimens.

scientific article

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

scientific article published on 23 January 2017

A study of stabilisation of p53 protein versus point mutation in colorectal carcinoma

scientific article published on 01 September 1994

Abstract 1994: Defining peritumoral and tumoral stromal gene signatures associated with response to neoadjuvant chemotherapy in breast cancer

article

Abstract P4-19-02: Early experience of patient donation and researcher use of tissues donated to a national breast cancer tissue bank

Adult Langerhans Cell Histiocytosis Mimicking Paget's Disease of the Nipple

scientific article published on 01 July 2005

An integrated informatics platform to facilitate transforming tissue into knowledge.

scientific article

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article published on 01 February 2019

Axillary lymph node core biopsy for breast cancer metastases -- how many needle passes are enough?

scientific article published on 26 November 2011

Axillary lymph nodes downstaging by neo-adjuvant chemotherapy for breast cancer

Biomarker discordance: prospective and retrospective evidence that biopsy of recurrent disease is of clinical utility

scientific article published on January 2012

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

scientific article published on 26 September 2016

CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations

scientific article published on 23 September 2013

Can additional histopathological examination of ultrasound-guided axillary lymph node core biopsies improve preoperative diagnosis of primary breast cancer nodal metastasis?

scientific article

Clinical value of internal mammary lymph node metastases found incidentally during free flap recipient vessel exposure

scientific article published on 4 April 2013

Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays.

scientific article

Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy

scientific article published on September 2010

Correlation of X-ray diffraction signatures of breast tissue and their histopathological classification.

scientific article published on 11 October 2017

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

scientific article published in October 2017

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on May 2016

Counting alleles to predict recurrence of early-stage colorectal cancers

scientific article published on January 2002

Differential contextual responses of normal human breast epithelium to ionizing radiation in a mouse xenograft model

scientific article published on 16 November 2010

Differential p53 protein expression in breast cancer fine needle aspirates: the potential for in vivo monitoring

scientific article published on October 2001

Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification.

scientific article

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?

scientific article

Dynamic response to heat – A novel physical characteristic of breast cancer

scientific article published on 08 February 2008

Efficacy of tumoricidal agentsin vitro andin vivo

scientific article published on 01 August 1995

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial.

scientific article

Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial

scientific article published on 15 February 2015

Expression of migration stimulating factor in breast tissues and its clinical significance.

scientific article published on 18 May 2010

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer

scientific article

FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.

scientific article

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on 11 May 2015

Giant Pendulous Fibroma of the Breast Associated with a Locally Advanced Carcinoma of the Breast

HER2 assessment on core biopsy specimens using monoclonal antibody CB11 accurately determines HER2 status in breast carcinoma

scientific article

HER2 testing for breast carcinoma: recommendations for rapid diagnostic pathways in clinical practice.

scientific article published on 23 September 2013

High CCND1 amplification identifies a group of poor prognosis women with estrogen receptor positive breast cancer

scientific article published on 01 July 2010

High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22.

scientific article published in October 1989

High frequency of complex TP53 mutations in CNS metastases from breast cancer.

scientific article published on 20 December 2011

Histological evaluation of AMPK signalling in primary breast cancer

scientific article published in September 2009

Histopathological grade, mucinous differentiation and DNA ploidy in relation to prognosis in colorectal carcinoma

scientific article published on 01 February 2000

Identification and role of migration stimulating factor isoforms in breast carcinomas.

scientific article published on 13 May 2008

Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom

scientific article

Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study

scientific article

Interim heterogeneity changes measured using entropy texture features on T2-weighted MRI at 3.0 T are associated with pathological response to neoadjuvant chemotherapy in primary breast cancer

scientific article published on 18 May 2017

Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors

scientific article published on 20 April 2012

Involved anterior margins after breast conserving surgery: is re-excision required?

scientific article published on 27 January 2012

Is the size of sentinel lymph node macrometastasis predictive for further positive axillary nodes on surgical clearance?

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism.

scientific article

Macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment: review of pathological issues and suggested approaches.

scientific article

Magnetic resonance imaging texture analysis classification of primary breast cancer

scientific article

Management of in situ lobular neoplasia detected on needle core biopsy of breast

scientific article published on 01 November 2010

Meta-analysis of sentinel node biopsy in ductal carcinoma in situ of the breast

scientific article published on May 2008

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Multiparameter DNA content analysis identifies distinct groups in primary breast cancer.

scientific article published on 14 February 2013

Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status.

scientific article published on 21 May 2014

Non-histopathological parameters associated with upgrade of breast tumours yielding a core biopsy report of histological grade 2 ductal no special type to grade 3 on excision

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival

Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy for Primary Breast Cancer Comparing Interim Ultrasound, Shear Wave Elastography and MRI.

scientific article published on 21 September 2017

Preoperative estimation of the prognosis of invasive breast cancer, based on ultrasound size, core biopsy grade and percutaneous axillary lymph node biopsy

scientific article

Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study

scientific article published on 03 December 2013

Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS).

scientific article

Quantitative shear wave ultrasound elastography: initial experience in solid breast masses

scientific article

Recurrent urachal adenocarcinoma.

scientific article published in November 2003

Sentinel node biopsy in breast cancer has a greater node positivity rate than axillary node sample: results from a retrospective analysis

scientific article published on 15 May 2012

Shear wave elastography of breast cancer: Sensitivity according to histological type in a large cohort.

scientific article published on 18 February 2016

Shear-wave elastography and greyscale assessment of palpable probably benign masses: is biopsy always required?

scientific article

Soft-embalmed human breast tissue as a model for pre-clinical trials of HIFU - preliminary results.

scientific article published on 30 June 2015

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

scientific article

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer

scientific article published on 01 May 1993

Stiffness at shear-wave elastography and patient presentation predicts upgrade at surgery following an ultrasound-guided core biopsy diagnosis of ductal carcinoma in situ

scientific article published on 5 August 2016

TP53 drives invasion through expression of its Δ133p53β variant

scientific article published on 15 September 2016

The Informatics Challenges Facing Biobanks: A Perspective from a United Kingdom Biobanking Network.

scientific article

The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer

scientific article

The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example

scientific article published on 19 October 2012

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer

scientific article

Thymocyte apoptosis induced by p53-dependent and independent pathways

scientific article

Tissue confirmation of disease recurrence in breast cancer patients: pooled analysis of multi-centre, multi-disciplinary prospective studies.

scientific article

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

article

Viewpoint: Availability of oestrogen receptor and HER2 status for the breast multidisciplinary meeting discussion; time to get it right.

scientific article

What are the characteristics of breast cancers misclassified as benign by quantitative ultrasound shear wave elastography?

scientific article

Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency

scientific article

p53 expression in colorectal tumors.

scientific article published on April 1991

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.

scientific article

p53 mutation, deprivation and poor prognosis in primary breast cancer

scientific article

List of works by Colin A Purdie

17q allele loss is associated with lymph node metastasis in locally aggressive human colorectal cancer

A candidate molecular signature associated with tamoxifen failure in primary breast cancer

A comparison of the imaging features of pleomorphic and classical invasive lobular carcinoma

A feasibility study of soft embalmed human breast tissue for preclinical trials of HIFU- preliminary results

A prognostic index for operable, node-negative breast cancer.

A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer

A simple and rapid approach to the problem of tissue contamination and patient identity in histopathologic specimens.

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

A study of stabilisation of p53 protein versus point mutation in colorectal carcinoma

Abstract 1994: Defining peritumoral and tumoral stromal gene signatures associated with response to neoadjuvant chemotherapy in breast cancer

Abstract P4-19-02: Early experience of patient donation and researcher use of tissues donated to a national breast cancer tissue bank

Adult Langerhans Cell Histiocytosis Mimicking Paget's Disease of the Nipple

An integrated informatics platform to facilitate transforming tissue into knowledge.

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Axillary lymph node core biopsy for breast cancer metastases -- how many needle passes are enough?

Axillary lymph nodes downstaging by neo-adjuvant chemotherapy for breast cancer

Biomarker discordance: prospective and retrospective evidence that biopsy of recurrent disease is of clinical utility

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations

Can additional histopathological examination of ultrasound-guided axillary lymph node core biopsies improve preoperative diagnosis of primary breast cancer nodal metastasis?

Clinical value of internal mammary lymph node metastases found incidentally during free flap recipient vessel exposure

Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays.

Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy

Correlation of X-ray diffraction signatures of breast tissue and their histopathological classification.

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Counting alleles to predict recurrence of early-stage colorectal cancers

Differential contextual responses of normal human breast epithelium to ionizing radiation in a mouse xenograft model

Differential p53 protein expression in breast cancer fine needle aspirates: the potential for in vivo monitoring

Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification.

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?

Dynamic response to heat – A novel physical characteristic of breast cancer

Efficacy of tumoricidal agentsin vitro andin vivo

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial.

Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial

Expression of migration stimulating factor in breast tissues and its clinical significance.

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer

FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Giant Pendulous Fibroma of the Breast Associated with a Locally Advanced Carcinoma of the Breast

HER2 assessment on core biopsy specimens using monoclonal antibody CB11 accurately determines HER2 status in breast carcinoma

HER2 testing for breast carcinoma: recommendations for rapid diagnostic pathways in clinical practice.

High CCND1 amplification identifies a group of poor prognosis women with estrogen receptor positive breast cancer

High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22.

High frequency of complex TP53 mutations in CNS metastases from breast cancer.

Histological evaluation of AMPK signalling in primary breast cancer

Histopathological grade, mucinous differentiation and DNA ploidy in relation to prognosis in colorectal carcinoma

Identification and role of migration stimulating factor isoforms in breast carcinomas.

Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom

Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study

Interim heterogeneity changes measured using entropy texture features on T2-weighted MRI at 3.0 T are associated with pathological response to neoadjuvant chemotherapy in primary breast cancer

Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors

Involved anterior margins after breast conserving surgery: is re-excision required?

Is the size of sentinel lymph node macrometastasis predictive for further positive axillary nodes on surgical clearance?

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism.

Macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment: review of pathological issues and suggested approaches.

Magnetic resonance imaging texture analysis classification of primary breast cancer

Management of in situ lobular neoplasia detected on needle core biopsy of breast

Meta-analysis of sentinel node biopsy in ductal carcinoma in situ of the breast

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Multiparameter DNA content analysis identifies distinct groups in primary breast cancer.

Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status.

Non-histopathological parameters associated with upgrade of breast tumours yielding a core biopsy report of histological grade 2 ductal no special type to grade 3 on excision

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival

Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy for Primary Breast Cancer Comparing Interim Ultrasound, Shear Wave Elastography and MRI.

Preoperative estimation of the prognosis of invasive breast cancer, based on ultrasound size, core biopsy grade and percutaneous axillary lymph node biopsy

Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study

Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS).

Quantitative shear wave ultrasound elastography: initial experience in solid breast masses

Recurrent urachal adenocarcinoma.

Sentinel node biopsy in breast cancer has a greater node positivity rate than axillary node sample: results from a retrospective analysis

Shear wave elastography of breast cancer: Sensitivity according to histological type in a large cohort.

Shear-wave elastography and greyscale assessment of palpable probably benign masses: is biopsy always required?

Soft-embalmed human breast tissue as a model for pre-clinical trials of HIFU - preliminary results.

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer

Stiffness at shear-wave elastography and patient presentation predicts upgrade at surgery following an ultrasound-guided core biopsy diagnosis of ductal carcinoma in situ

TP53 drives invasion through expression of its Δ133p53β variant