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List of works by Marek Trněný

5-azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity.

scientific article

A Phase 2/3 Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Lenalidomide Versus Investigator's Choice in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

scientific article

A new prognostic score for elderly patients with diffuse large B-cell lymphoma treated with R-CHOP: the prognostic role of blood monocyte and lymphocyte counts is absent

scientific article

A randomized study of interferon α-2b versus no treatment as consolidation after high dose therapy and autologous stem cell transplantation for patients with relapsed lymphoma

scientific article published on 08 October 2013

Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial ⬇️

scientific article published on October 2, 2010

Aleukemic granulocytic sarcoma with AML1/ETO fusion gene expression and clonal T cell populations.

scientific article published in December 2001

Alterations of CHEK2 forkhead-associated domain increase the risk of Hodgkin lymphoma.

scientific article

Alternating R-CHOP and R-cytarabine is a safe and effective regimen for transplant-ineligible patients with a newly diagnosed mantle cell lymphoma.

scientific article

Anaplastic Large-Cell Lymphoma Associated with Breast Implants: A Case Report of a Transgender Female.

scientific article published on 3 November 2017

Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma

scientific article published on 27 October 2015

Biallelic IgH rearrangements in patients with indolent lymphoproliferative disorders: molecular and practical implications.

scientific article published in May 2004

CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group

scientific article

CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group

scientific article published on 21 September 2011

Chemotherapy alone may lead to a PCR negative stem cell harvest in transformed lymphoma refractory to rituximab.

scientific article

Clonal evolution in chronic lymphocytic leukemia studied by interphase fluorescence in-situ hybridization.

scientific article published in January 2009

Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study

scientific article published on 20 June 2022

Confirmation of the mantle-cell lymphoma International Prognostic Index in randomized trials of the European Mantle-Cell Lymphoma Network

scientific article published on 31 March 2014

Determining the extent and stage of disease in patients with newly diagnosed non-Hodgkin's lymphoma using 18F-FDG-PET/CT.

scientific article published in January 2011

Distinguishing of primary mediastinal B-cell lymphoma and diffuse large B-cell lymphoma using real-time quantitative polymerase chain reaction

scientific article published on 01 January 2010

Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.

scientific article

ESMO Guidelines consensus conference on malignant lymphoma 2011 part 1: diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL).

scientific article

Endothelial cells (EC) and endothelial precursor cells (EPC) kinetics in hematological patients undergoing chemotherapy or autologous stem cell transplantation (ASCT).

scientific article

Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy

scientific article

Expression patterns of microRNAs associated with CML phases and their disease related targets

scientific article

Familial chronic lymphocytic leukemia

scientific article published on 01 October 2003

Final analysis of the UKLG LY02 trial comparing 6-8 cycles of CHOP with 3 cycles of CHOP followed by a BEAM autograft in patients <65 years with poor prognosis histologically aggressive NHL.

scientific article published in March 2010

First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, open-label, randomised, phase 3, non-inferiority tri

scientific article published on 20 May 2016

Follicular Lymphoma

scientific article published on January 2015

Frontline intensive chemotherapy improves outcome in young, high-risk patients with follicular lymphoma: pair-matched analysis from the Czech Lymphoma Study Group Database.

scientific article published on 25 September 2016

Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement

scientific article published on 5 January 2017

Heterochromatin condensation in central and peripheral nuclear regions of maturing lymphocytes in the peripheral blood of patients suffering from B chronic lymphocytic leukemia - a cytochemical study

scientific article published on 01 January 2011

High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience.

scientific article published on 29 March 2010

Hodgkin´s Lymhoma - the Treatment Aproaches Development and Current Trends

scientific article published on January 2015

Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study

scientific article published on 04 December 2015

Identification of prognostic factors predicting outcome in Hodgkin's lymphoma patients relapsing after autologous stem cell transplantation

scientific article published on 26 May 2013

Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: can we compare real life data to the results from clinical trials?

scientific article

Impact of rituximab maintenance and maintenance schedule on prognosis in first-line treatment of follicular lymphoma. Retrospective analysis from Czech Lymphoma Study Group (CLSG) database.

scientific article published on 21 August 2015

Implications of the European Organisation for Research And Treatment Of Cancer (EORTC) guidelines on the use of granulocyte colony-stimulating factor (G-CSF) for lymphoma care

scientific article published on January 2009

Incidence of Second Primary Malignancies after Autologous Transplantation for Multiple Myeloma in the Era of Novel Agents

scientific article published on 12 January 2018

Individually determined dosing of filgrastim after autologous peripheral stem cell transplantation in patients with malignant lymphoma--results of a prospective multicentre controlled trial

scientific article published on 17 October 2006

Intrapleural bortezomib for the therapy of myelomatous pleural effusion: a case report

scientific article

Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells.

scientific article published on 3 December 2015

Lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma (MCL-002; SPRINT): a phase 2, randomised, multicentre trial

scientific article

Long-term Outcomes After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis

scientific article

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia

scientific article

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma

scientific article published on 2 February 2018

Malignant Lymphomas - Past, Present and Future

scientific article published on January 2015

Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years.

scientific article published on 12 July 2016

Microscopic notes on the perinucleolar chromatin region in immature and mature human B-leukemia lymphocytes.

scientific article

Microvessel density of mantle cell lymphoma. A retrospective study of its prognostic role and the correlation with the Ki-67 and the mantle cell lymphoma international prognostic index in 177 cases.

scientific article

Minimal residual disease detectable by quantitative assessment of WT1 gene before allogeneic stem cell transplantation in patients in first remission of acute myeloid leukemia has an impact on their future prognosis

scientific article

Modern and conventional prognostic markers of chronic lymphocytic leukaemia in the everyday haematological practice.

scientific article published in August 2011

Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study

scientific article

Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research.

scientific article

Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL).

scientific article published on January 2013

Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin.

scientific article

Nivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial

article

Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

scientific article

No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma

scientific article published on 05 May 2011

Obinutuzumab for the First-Line Treatment of Follicular Lymphoma

scientific article published in October 2017

Obinutuzumab or Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Previously Untreated Diffuse Large B-Cell Lymphoma.

scientific article

Obinutuzumab plus bendamustine versus bendamustine monotherapy in patients with rituximab-refractory indolent non-Hodgkin lymphoma (GADOLIN): a randomised, controlled, open-label, multicentre, phase 3 trial

scientific article

Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia

scientific article

Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia

scientific article

Oncogenic microRNA-155 and its target PU.1: an integrative gene expression study in six of the most prevalent lymphomas.

scientific article published on 11 August 2015

Optimized protocol for gene expression analysis in formalin-fixed, paraffin-embedded tissue using real-time quantitative polymerase chain reaction

scientific article published on 01 September 2009

Outcome and prognostic factors in patients with mantle-cell lymphoma relapsing after autologous stem-cell transplantation: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT)

scientific article published on 27 February 2014

Outcome of patients with relapsed diffuse large B-cell lymphoma who fail second-line salvage regimens in the International CORAL study.

scientific article published on 14 September 2015

Outcomes of diffuse large B-cell lymphoma patients relapsing after autologous stem cell transplantation: an analysis of patients included in the CORAL study

scientific article

PBPC collections: Management, techniques and risks.

scientific article published on 3 August 2010

Peripheral T-cell lymphoma, unspecified--the analysis of the data from the Czech Lymphoma Study Group (CLSG) registry.

scientific article

Pharmacokinetics, safety, and efficacy of subcutaneous versus intravenous rituximab plus chemotherapy as treatment for chronic lymphocytic leukaemia (SAWYER): a phase 1b, open-label, randomised controlled non-inferiority trial

scientific article

Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-Cell Lymphomas.

scientific article published on 15 October 2017

Positron emission tomography at the end of first-line therapy and during follow-up in patients with Hodgkin lymphoma: a retrospective study.

scientific article published on 9 November 2009

Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma

scientific article published on 23 June 2011

Prognostic value of MRD in CLL patients with comorbidities receiving chlorambucil plus obinutuzumab or rituximab

scientific article published on 19 November 2018

Radiotherapy with rituximab may be better than radiotherapy alone in first-line treatment of early-stage follicular lymphoma: is it time to change the standard strategy?

scientific article

Reply to the letter to the editor by Guinn et al

scientific article published on 02 October 2011

Retrospective analysis of 235 unselected patients with mantle cell lymphoma confirms prognostic relevance of Mantle Cell Lymphoma International Prognostic Index and Ki-67 in the era of rituximab: long-term data from the Czech Lymphoma Project Databa

scientific article

Risk Factors and Outcomes for Patients With Follicular Lymphoma Who Had Histologic Transformation After Response to First-Line Immunochemotherapy in the PRIMA Trial.

scientific article published on 13 June 2016

Rituximab based therapy followed by autologous stem cell transplantation leads to superior outcome and high rates of PCR negativity in patients with indolent B-cell lymphoproliferative disorders

scientific article published on 01 August 2009

Rituximab maintenance for patients with aggressive B-cell lymphoma in first remission: results of the randomized NHL13 trial

scientific article published on 24 April 2015

Rituximab maintenance therapy after autologous stem-cell transplantation in patients with relapsed CD20(+) diffuse large B-cell lymphoma: final analysis of the collaborative trial in relapsed aggressive lymphoma

scientific article published on 22 October 2012

Role of rituximab in treatment of patients with primary central nervous system lymphoma: a retrospective analysis of the Czech lymphoma study group registry

scientific article published on 18 April 2016

Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis

scientific article

Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era

scientific article

Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL.

scientific article published on 15 February 2017

Should the standard dimethyl sulfoxide concentration be reduced? Results of a European Group for Blood and Marrow Transplantation prospective noninterventional study on usage and side effects of dimethyl sulfoxide

scientific article published on 26 June 2014

Significantly higher numbers of proB cells in healthy Caucasians compared to Asians: Is there association with incidence of CLL?

scientific article

Single nucleotide polymorphism in 5'-flanking region of BCL6 is not associated with increased risk of non-Hodgkin's lymphoma

scientific article published on 25 August 2005

Single-agent cytarabine is insufficient for the treatment of human mantle cell lymphoma in mouse xenograft model

scientific article published on 01 January 2016

Symptoms and toxicity of rituximab maintenance relative to observation following immunochemotherapy in patients with follicular lymphoma

scientific article

Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma.

scientific article published on 14 October 2015

Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia.

scientific article published in January 2010

The Hans algorithm failed to predict outcome in patients with diffuse large B-cell lymphoma treated with rituximab.

scientific article published in January 2013

The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering

scientific article

The effect of allogeneic stem cell transplantation on high risk chronic lymphocytic leukaemia: a single centre retrospective analysis

scientific article published on 01 March 2011

The evaluation of survival and proliferation of lymphocytes in autologous mixed leukocyte reaction with dendritic cells. The comparison of incorporation of (3)H-thymidine and differential gating method

scientific article published on 06 July 2011

The quality of life following allogeneic hematopoietic stem cell transplantation - a multicenter retrospective study.

scientific article published on 29 July 2016

The results of allogeneic transplants in patients with malignant lymphoma-a retrospective analysis of data from the Czech National Registry

scientific article

The use of formalin-fixed, paraffin-embedded lymph node samples for the detection of minimal residual disease in mantle cell lymphoma

scientific article published on 14 October 2014

To the nucleolar bodies (nucleoli) in cells of the lymphocytic lineage in patients suffering from B - chronic lymphocytic leukemia

scientific article published on 01 January 2010

Treatment for patients with relapsed/refractory mantle cell lymphoma: European-based recommendations.

scientific article published on 27 November 2017

Treatment of high-risk aggressive B-cell non-Hodgkin lymphomas with rituximab, intensive induction and high-dose consolidation: long-term analysis of the R-MegaCHOP-ESHAP-BEAM Trial.

scientific article published on 29 April 2014

Treatment of older patients with mantle-cell lymphoma.

scientific article

Unusual sequence of VDJ rearrangement revealed by molecular analysis in a patient with indolent lymphoma ⬇️

scientific article published on May 1, 2003

Update on the molecular pathogenesis and clinical treatment of Mantle Cell Lymphoma (MCL): minutes of the 9th European MCL Network conference.

scientific article published on September 2010

[Current Approaches in Cancer Immunotherapy]

scientific article published on 01 January 2015

[Salvage Treatment and the Role of Transplantation in Lymphomas]

scientific article published on 01 January 2015

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