List of works - Marc J. Ruitenberg

A case of mistaken identity: CD11c-eYFP(+) cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells.

scientific article

A meta-analysis of microarray-based gene expression studies of olfactory bulb-derived olfactory ensheathing cells.

scientific article published on 23 March 2011

A novel in vitro human microglia model: characterization of human monocyte-derived microglia.

scientific article

Absence of the C5a Receptor C5aR2 Worsens Ischemic Tissue Injury by Increasing C5aR1-Mediated Neutrophil Infiltration

scientific article published on 07 October 2020

Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1.

scientific article published on 13 May 2011

Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats

scientific article published on June 2013

Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

scientific article published in March 2004

Adeno-associated viral vectors as agents for gene delivery: application in disorders and trauma of the central nervous system.

scientific article

Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord

scientific article published in October 2002

An atypical role for the myeloid receptor Mincle in central nervous system injury

scientific article

Bone marrow chimeric mice reveal a role for CX3 CR1 in maintenance of the monocyte-derived cell population in the olfactory neuroepithelium

scientific article published on 07 July 2010

CX3CL1/fractalkine regulates branching and migration of monocyte-derived cells in the mouse olfactory epithelium

scientific article published on 31 October 2008

CX₃CR1 deficiency exacerbates neuronal loss and impairs early regenerative responses in the target-ablated olfactory epithelium

scientific article published on 16 August 2011

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

scientific article

Complement activation in the injured central nervous system: another dual-edged sword?

scientific article published on 21 June 2012

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2.

scientific article published on 2 May 2019

Dendritic cells and multiple sclerosis: disease, tolerance and therapy

scientific article published on 27 December 2012

Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.

scientific article published on 23 June 2012

Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy.

scientific article published on 11 January 2017

Enrichment increases hippocampal neurogenesis independent of blood monocyte-derived microglia presence following high-dose total body irradiation

scientific article published on 24 May 2017

Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord.

scientific article published in August 2003

Exacerbation of Acute Traumatic Brain Injury by Circulating Extracellular Vesicles

scientific article published on 17 November 2017

Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS.

scientific article published in February 1999

Feasibility study of real-time three-/four-dimensional ultrasound for epidural catheter insertion

scientific article

IVIg attenuates complement and improves spinal cord injury outcomes in mice.

scientific article published on 25 May 2016

Immature doublecortin-positive hippocampal neurons are important for learning but not for remembering.

scientific article published in April 2013

Immune cell trafficking from the brain maintains CNS immune tolerance

scientific article published on 24 February 2014

Influence of adult Schwann cells and olfactory ensheathing glia on axon--target cell interactions in the CNS: a comparative analysis using a retinotectal co-graft model.

scientific article published in May 2007

Injury-induced class 3 semaphorin expression in the rat spinal cord

scientific article published on May 2002

It takes nerve to fight back: The significance of neural innervation of the bone marrow and spleen for immune function.

scientific article published on 11 August 2016

Lack of fibulin-3 alters regenerative tissue responses in the primary olfactory pathway.

scientific article published on 9 June 2009

Local and Remote Immune-Mediated Inflammation After Mild Peripheral Nerve Compression in Rats ⬇️

scientific article published on July 1, 2013

Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function

scientific article published in March 2012

Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4 T) in vivo diffusion tensor imaging

scientific article

MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury

scientific article published on 01 August 2019

Microglia modulate hippocampal neural precursor activity in response to exercise and aging

scientific article published in May 2012

Mobilisation of the splenic monocyte reservoir and peripheral CX₃CR1 deficiency adversely affects recovery from spinal cord injury.

scientific article published on 9 May 2013

NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration

scientific article published on 16 February 2005

Novel characterization of monocyte-derived cell populations in the meninges and choroid plexus and their rates of replenishment in bone marrow chimeric mice

scientific article

Olfactory ensheathing cells: characteristics, genetic engineering, and therapeutic potential

scientific article (publication date: 2006)

PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

scientific article

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

scientific article

Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat.

scientific article published in January 2006

Promoting central nervous system regeneration: lessons from cranial nerve I.

scientific article published on January 2008

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

scientific article published on October 2004

Semaphorins and their receptors in olfactory axon guidance.

scientific article

Targeting acute inflammation to complement spinal cord repair.

scientific article

The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury.

scientific article published on 7 February 2017

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury

scientific article

The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium.

scientific article

The glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing cells in vitro

scientific journal article

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.

scientific article published on 21 May 2013

Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions

scientific article published on 2 April 2016

Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system

scientific article published in January 2009

Vertebral landmarks for the identification of spinal cord segments in the mouse

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord.

scientific article

Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord.

scientific article published on January 2004

p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model

scientific article published on 30 July 2019

List of works by Marc J. Ruitenberg

A case of mistaken identity: CD11c-eYFP(+) cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells.

A meta-analysis of microarray-based gene expression studies of olfactory bulb-derived olfactory ensheathing cells.

A novel in vitro human microglia model: characterization of human monocyte-derived microglia.

Absence of the C5a Receptor C5aR2 Worsens Ischemic Tissue Injury by Increasing C5aR1-Mediated Neutrophil Infiltration

Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1.

Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats

Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

Adeno-associated viral vectors as agents for gene delivery: application in disorders and trauma of the central nervous system.

Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord

An atypical role for the myeloid receptor Mincle in central nervous system injury

Bone marrow chimeric mice reveal a role for CX3 CR1 in maintenance of the monocyte-derived cell population in the olfactory neuroepithelium

CX3CL1/fractalkine regulates branching and migration of monocyte-derived cells in the mouse olfactory epithelium

CX₃CR1 deficiency exacerbates neuronal loss and impairs early regenerative responses in the target-ablated olfactory epithelium

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

Complement activation in the injured central nervous system: another dual-edged sword?

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2.

Dendritic cells and multiple sclerosis: disease, tolerance and therapy

Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.

Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy.

Enrichment increases hippocampal neurogenesis independent of blood monocyte-derived microglia presence following high-dose total body irradiation

Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord.

Exacerbation of Acute Traumatic Brain Injury by Circulating Extracellular Vesicles

Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS.

Feasibility study of real-time three-/four-dimensional ultrasound for epidural catheter insertion

IVIg attenuates complement and improves spinal cord injury outcomes in mice.

Immature doublecortin-positive hippocampal neurons are important for learning but not for remembering.

Immune cell trafficking from the brain maintains CNS immune tolerance

Influence of adult Schwann cells and olfactory ensheathing glia on axon--target cell interactions in the CNS: a comparative analysis using a retinotectal co-graft model.

Injury-induced class 3 semaphorin expression in the rat spinal cord

It takes nerve to fight back: The significance of neural innervation of the bone marrow and spleen for immune function.

Lack of fibulin-3 alters regenerative tissue responses in the primary olfactory pathway.

Local and Remote Immune-Mediated Inflammation After Mild Peripheral Nerve Compression in Rats ⬇️

Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function

Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4 T) in vivo diffusion tensor imaging

MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury

Microglia modulate hippocampal neural precursor activity in response to exercise and aging

Mobilisation of the splenic monocyte reservoir and peripheral CX₃CR1 deficiency adversely affects recovery from spinal cord injury.

NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration

Novel characterization of monocyte-derived cell populations in the meninges and choroid plexus and their rates of replenishment in bone marrow chimeric mice

Olfactory ensheathing cells: characteristics, genetic engineering, and therapeutic potential

PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat.

Promoting central nervous system regeneration: lessons from cranial nerve I.

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

Semaphorins and their receptors in olfactory axon guidance.

Targeting acute inflammation to complement spinal cord repair.

The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury.

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury

The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium.

The glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing cells in vitro

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.

Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions

Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system

Vertebral landmarks for the identification of spinal cord segments in the mouse

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord.

Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord.

p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model