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List of works by Darren J. Burgess

Alternative splicing: proteomic rewiring through transcriptomic diversity

scientific article published on 18 July 2012

Aneuploidy stokes the fire

scientific article published on 8 September 2011

Aneuploidy stokes the fire

scientific article published on 31 August 2011

Angiogenesis: A happy medium?

scientific article published on 13 December 2012

Anticancer Drugs: Selective oxycution?

scientific article published on 31 August 2011

Anticancer drugs: Antipsychotic to anticancer agent?

scientific article published on 29 June 2012

Anticancer drugs: Antitumour potential of catalytic DNA

scientific article published on 01 August 2012

Anticancer drugs: Assault on MALT1

scientific article published on 01 February 2013

Anticancer drugs: Keeping one step ahead

scientific article published on 01 February 2012

Anticancer drugs: SRC hits the mark

scientific article published on 01 May 2011

Anticancer drugs: blocking RAS effects

scientific article published in June 2013

Antitumour potential of catalytic DNA

scientific article published on July 24, 2012

Apoptosis: Refined and lethal

scientific article

At the hypusine of the crime

scientific article published on 05 July 2012

Bacterial genetics: sRNA toolkit for Vibrio

scientific article published on 27 January 2015

Biotechnology: Making a meal of RNA.

scientific article published on 10 March 2015

Breast cancer: Circulating and dynamic EMT

scientific article published on 14 February 2013

Breast cancer: SRC hits the mark

scientific article published on 14 April 2011

Cancer epigenetics: Therapy-induced transcription is cryptically widespread

scientific article published on 26 June 2017

Cancer genetics: CRISPR screens go in vivo

scientific article published in April 2015

Cancer genetics: HIF enhances its reputation

scientific article published on 12 April 2012

Cancer genetics: Initially complex, always heterogeneous

scientific article published on 25 January 2011

Cancer genetics: Initially complex, always heterogeneous

scientific article published on 28 January 2011

Cancer genetics: Leveraging functional data for driver genes

scientific article

Cancer genetics: omics analyses of tumour immunity

scientific article published on 10 February 2015

Cancer genomics: Histone modification at the gene level

scientific article published on 14 February 2012

Cancer genomics: Translocation patterns revealed

scientific article published on 18 October 2011

Cancer: Lethal cycling

scientific article published on 01 September 2010

Chromatin: Histone influences on chromosomal translocations

scientific article published on 07 July 2015

Chromatin: Histone influences on chromosomal translocations

scientific article published on 15 July 2015

Chromatin: Nucleosomal dynamics at centromeres

scientific article published on 01 September 2012

Chromatin: Probing a piRNA paradox

scientific article

Chromatin: nucleosomal dynamics at centromeres

scientific article published on 07 August 2012

Chromosome instability: Chaos from within

scientific article published on 01 April 2011

Chromosome instability: Tumorigenesis via satellite link

scientific article published on 01 March 2011

Chromosomes: Dynamically in the loop

scientific article published on 20 May 2014

Comparative genomics: mammalian alignments reveal human functional elements

scientific article published on 03 November 2011

Complex traits: Old meets new in obesity genetics

scientific article published on 03 April 2012

DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1

scientific article

DNA repair: A single-edged sword?

scientific article published on 01 January 2011

DNA sequencing: Real-time prioritization of sequencing output

scientific article published on 01 August 2016

Development: Differentiation goes up a Notch

scientific article published on 15 March 2011

Development: Sonic snakes and regulation of limb formation

scientific article published on 01 November 2016

Disease genetics: Double danger from mitochondrial mutations

scientific article published on 11 September 2013

Disease genetics: Network effects of disease mutations

scientific article published on 01 June 2015

Disease genetics: Prion variant pathogenicity through large-scale population sequencing

scientific article published on 01 February 2016

Disease genetics: all together now for variant interpretation

scientific article published on 18 February 2014

Disease mechanisms: Out with the old, in with the new

scientific article published on 22 July 2011

Epigenetics. Dissecting driving DNA methylations

scientific article published on 07 June 2012

Epigenetics: Bacterial DNA methylation gets SMRT.

scientific article published on 27 November 2012

Epigenetics: H3K27 methylation in transgenerational epigenetic memory

scientific article published in November 2014

Epigenetics: Melanoma insights written in the DNA

scientific article published on 05 October 2012

Epigenetics: Rich pore methods for DNA methylation detection

scientific article published on 01 March 2017

Epigenetics: Separate paths for epigenomes and genomes in cancer evolution?

scientific article published on 01 July 2016

Epigenomics: Custom remodelling

scientific article published on 08 February 2016

Epigenomics: Deciphering non-coding variation with 3D epigenomics

scientific article published on 01 December 2016

Evo-devo: Hidden rewiring comes to light

scientific article published on 09 August 2011

Evolution: A matter of balance

scientific article published on 26 February 2013

Evolution: An eye for cryptic variation

scientific article published on 24 December 2013

Evolution: Cancer drivers everywhere?

scientific article published on 25 March 2014

Evolution: Experimental evolution probes neighbourly niches

scientific article published on 12 March 2013

Evolution: Polyploid gains

scientific article published on 01 April 2015

Evolution: boom and robust

scientific article published on 4 March 2014

Evolutionary genetics: Haunted by the past--modern consequences of Neanderthal DNA

scientific article published on 07 March 2016

Evolutionary genetics: Knowing when to stop

scientific article published on 25 July 2016

Functional genomics: A drop in an ocean of gene variants

scientific article published on 22 January 2018

Functional genomics: Shining a light on genetic screen strategies

scientific article published on 13 November 2017

Gene expression: A space for transcriptomics

scientific article published on 01 July 2016

Gene expression: Host-pathogen duels revealed by dual RNA-seq in vivo

scientific article

Gene expression: More roles and details for polymerase pausing

scientific article published on 29 May 2012

Gene expression: Principles of gene regulation across tissues

scientific article published on 7 November 2017

Gene expression: Systematic tuning of expression

scientific article published on 01 September 2016

Gene expression: Time flies thanks to Pol II pausing

scientific article

Gene expression: Variety is the splice of strife

scientific article published on 07 October 2011

Gene expression: colorectal cancer classifications

scientific article published on 03 May 2013

Gene expression: controls and roles for trans-splicing.

scientific article

Gene expression: dynamic omics responses

scientific article published on 14 November 2012

Gene expression: spatial characterization of proteomes

scientific article published on 10 February 2015

Gene expression: splicing steps aside to consider its options

scientific article published on 6 December 2011

Gene regulation: Characterizing monoallelic expression

scientific article published on 28 January 2014

Gene regulation: Finding genetic target sites

scientific article published on 18 April 2016

Gene regulation: RNAs feel the heat

scientific article published on 25 September 2012

Gene regulation: a chromatin-based recruitment drive

scientific article published on 15 July 2014

Gene regulation: multiple mechanisms of small RNAs

scientific article published on 01 February 2015

Gene therapy: insulating from genotoxicity

scientific article published on 28 January 2015

Genetic interactions: Leveraging context-dependent essentiality

scientific article published on 01 August 2016

Genetic screens: A global map of genetic interactions

scientific article published on 01 October 2016

Genetic screens: Combination screens for combination therapies

scientific article published on 12 April 2016

Genetic screens: Combining CRISPR perturbations and RNA-seq

scientific article published in January 2017

Genetic screens: Pol II interactions in detail

scientific article published on 21 August 2013

Genetic screens: RNA-seq into the toolkit

scientific article

Genetics. BRCA inequality

scientific article published on 17 November 2011

Genome stability: Chromosome correction through reprogramming

scientific article published on 4 February 2014

Genome stability: Specialist responses at telomeres

scientific article

Genomic instability: Shattered details

scientific article published on 02 February 2012

Genomic instability: close-up on cancer copy number alterations

scientific article published on 29 November 2011

Genomics: Getting personal and regional

scientific article published on 04 October 2011

Genomics: New zebrafish genome resources

scientific article published on 30 April 2013

Genomics: Organ roles for mitochondrial mutations?

scientific article

Glioblastoma: Microvesicles as major biomarkers?

scientific article published on 13 December 2012

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

scientific article

High-throughput RNAi screening reveals novel regulators of telomerase

scientific article

How pervasive are defective genes?

scientific article published on February 28, 2012

Human Disease: Next-generation sequencing of the next generation

scientific article published on 21 December 2010

Human epigenetics: Showing your age

scientific article published on 04 December 2012

Human evolution: making the most of damage

scientific article published on 20 August 2014

Human evolution: multigenome coalescence for modern demographic insights

scientific article published on 08 July 2014

Human evolution: reprogrammed cells dissect ape retrotransposition

scientific article published on 12 November 2013

Human genetics: Dissecting deleterious mutation complexity

scientific article published on 29 October 2014

Human genetics: Loss-of-function variants--not always what they seem

scientific article published on 14 March 2016

Human genetics: somatic mutations linked to future disease risk

scientific article published on 23 December 2014

Leukaemia: targeted therapy re-enABLed?

scientific article published on 16 June 2011

Major mathematical hurdles for biomarker-based screening

scientific article published on December 8, 2011

Metabolism: Epigenetic links to the web of Krebs

scientific article published on 20 June 2013

Metabolism: Glutamine connections

scientific article published on 12 April 2013

Metabolism: TAp63 tips the energy balance?

scientific article published on 18 October 2012

Metabolism: Unravelling metabolic dependencies

scientific article published on 24 May 2012

Metabolism: Warburg behind the butyrate paradox?

scientific article published on 15 November 2012

Metabolism: choose your carbon source

scientific article published on 01 February 2011

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

scientific article

MicroRNAs provide powerful postponement

scientific article published on November 30, 2010

Microbial genetics: Amplified origins of antibiotic resistance

scientific article published on 24 April 2014

Microbial genetics: Fitness from drug resistance

scientific article published on 03 January 2014

Microenvironment: A dense danger

scientific article published on 21 September 2012

Model organisms: the dangers lurking in the genetic background

scientific article published on 18 October 2011

Molecular evolution: Decoupled transcription factor output?

scientific article published on 02 December 2014

Multiple bypass problem for BRAF inhibition

scientific article published on 01 January 2011

Multiple myeloma: evolution by alternating dominance

scientific article published on 17 May 2012

One size does not fit all for transcriptomes

scientific article published on 23 November 2010

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

scientific article published on March 2010

Plant genetics: Branching out for crop improvement

scientific article published on 05 June 2017

Population genetics: Mobile elements across human populations

scientific article published on 9 May 2013

RNA stability: Remember your driver

scientific article published on 01 February 2011

RNA. Detailed probing of RNA structure in vivo

scientific article published on 09 April 2015

RNA: Putting transcriptomics in its place

scientific article published on 07 May 2015

Regulatory elements: Putting enhancers into context

scientific article published on 31 May 2016

Remember your driver

scientific article published on January 11, 2012

Reprogramming: Your contacts reveal your past

scientific article published on 21 March 2016

Senescence. NF-κB shows its beneficial side

scientific article published on 28 October 2011

Senescence: ConnectING endocytosis

scientific article published on 28 March 2013

Senescence: Double or quit?

scientific article published on 12 May 2011

Senescence: Tumorigenesis under surveillance

scientific article published on 01 December 2011

Sequencing: A sparkling standard

scientific article published on 22 August 2016

Shattered details

scientific article published on 02 February 2012

Signalling: vesicle vehicles of genetic information

scientific article published on 24 June 2014

Small RNAs: Defining piRNA expression.

scientific article

Small RNAs: antiviral RNAi in mammals.

scientific article published on 22 October 2013

Stem cells. Antipsychotic to anticancer agent?

scientific article published on 22 June 2012

Stem cells: Competitive behaviour of cancer mutations

scientific article published on 10 December 2013

Stem cells: Maintaining genomic integrity

scientific article published on 09 July 2013

Stem cells: competitive behaviour of cancer mutations

scientific article published on 01 January 2014

Stem cells: epigenome reprogramming--of mice and men.

scientific article published on 12 August 2014

Suppression of tumorigenesis by the p53 target PUMA

scientific article

Synthetic Biology: Building a custom eukaryotic genome de novo

scientific article published in April 2017

Synthetic biology: Cut up to bring together

scientific article published on 08 May 2014

Technique: CRISPR CAPTURE for multi-omic probing of genomic loci

scientific article published on 3 October 2017

Technique: Genome editing for cell lineage tracing

scientific article published on 13 June 2016

Technique: Transcript tracking by CRISPR.

scientific article published on 30 March 2016

Technology: A drop in single-cell challenges

scientific article published on 16 June 2015

Technology: Bead capture for single-cell transcriptomics

scientific article published on 24 February 2015

Technology: Enabling accurate single-cell genome amplification

scientific article published on 01 August 2016

Technology: go ahead, make my DNA

scientific article published on 17 May 2011

Technology: testing all possibilities

scientific article published on 03 September 2014

Technology: when two halves are better than one whole

scientific article published on 24 July 2012

The ARF tumor suppressor can promote the progression of some tumors.

scientific article published on December 2008

Therapeutics: Assault on MALT1

scientific article published on 10 January 2013

Therapeutics: Holding JAK back

scientific article published on 01 September 2012

Therapeutics: Keeping one step ahead

scientific article published on 12 January 2012

Therapeutics: blocking RAS effects

scientific article published on 16 May 2013

Therapy: Lethal cycling

scientific article published on 01 September 2010

Therapy: selective oxycution?

scientific article published on 12 August 2011

Tissue-specific and reversible RNA interference in transgenic mice

scientific article

Topoisomerase levels determine chemotherapy responsein vitroandin vivo

scientific article (publication date: 23 June 2008)

Transcription: Interference from near and far

scientific article published on 11 February 2014

Transcriptomics: Sense and antisense ability

scientific article published on 18 July 2011

Translational genetics: CRISPR therapies - making the grade not the cut.

scientific article published on 18 December 2017

Transposable elements: ERE and there for pluripotency.

scientific article published on July 2014

Tumorigenesis: Dangerous micromanagement

scientific article published on 01 October 2010

Tumour evolution: Weighed down by passengers?

scientific article published on 07 March 2013

Tumour immunology: Context is key for TSLP

scientific article published on 01 December 2012

Tumour immunology: Editorial selection demystified

scientific article published on 22 March 2012

Tumour suppressors: A microdependency of importance?

scientific article published on 01 October 2012

Tumour suppressors: At the SHARP end of metastasis

scientific article published on 09 August 2012

Unexpected mismatches, but dogma intact

scientific article published on June 17, 2011