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List of works by Alessandro Tossi

A computational study of the resistance of HIV-1 aspartic protease to the inhibitors ABT-538 and VX-478 and design of new analogues.

scientific article

A novel [60]fullerene amino acid for use in solid-phase peptide synthesis

scientific article published on 01 June 2001

A plant-defensin from sugarcane (Saccharum spp.).

scientific article published in January 2009

A study of host defence peptide beta-defensin 3 in primates

scientific article published on September 2003

An albumin-derived peptide scaffold capable of binding and catalysis

scientific article

Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'

scientific article published on 03 January 2008

Antimicrobial Peptides as Anti-Infective Agents in Pre-Post-Antibiotic Era?

scientific article published on 14 November 2019

Artificial beta-defensin based on a minimal defensin template.

scientific article published on 15 July 2009

Aspartic protease inhibitors

scientific article published in 2000

Beta-defensin 2 in the rhesus monkey (Macaca mulatta) and the long-tailed macaque (M. fascicularis).

scientific article published on March 2002

Binding of Ru(bpy)3(2+) and Ru(phen)3(2+) to polynucleotides and DNA: effect to added salts on the absorption and luminescence properties

scientific article published on 01 July 1988

Cellular internalization and cytotoxicity of the antimicrobial proline-rich peptide Bac7(1-35) in monocytes/macrophages, and its activity against phagocytosed Salmonella typhimurium

scientific article published on April 2014

Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

scientific article published on 06 October 2020

Characterization of a new defensin from cowpea (Vigna unguiculata (L.) Walp.).

scientific article published in March 2010

Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA.

scientific article published in January 1994

Comparative activity and mechanism of action of three types of bovine antimicrobial peptides against pathogenic Prototheca spp

scientific article published on 14 November 2011

Computational design of highly selective antimicrobial peptides.

scientific article published in December 2009

Computational studies of the resistance patterns of mutant HIV-1 aspartic proteases towards ABT-538 (ritonavir) and design of new derivatives

scientific article published in December 2002

Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity.

scientific article published on August 2005

DADP: the database of anuran defense peptides

scientific article published on 29 March 2012

Designing Short Peptides with High Affinity for Organic Molecules: A Combined Docking, Molecular Dynamics, And Monte Carlo Approach.

scientific article published on 28 February 2012

Editorial

Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7.

scientific article published on 14 January 2015

Effects of positively selected sequence variations in human and Macaca fascicularis beta-defensins 2 on antimicrobial activity.

scientific article

Effects on antigen-presenting cells of short-term interaction with the human host defence peptide β-defensin 2

scientific article published on 01 June 2011

Evolution of the beta defensin 2 gene in primates

article

Evolution of the hepcidin gene in primates

scientific article

Fungicidal activity of five cathelicidin peptides against clinically isolated yeasts

article published in 2006

Histatins in non-human primates: gene variations and functional effects.

scientific article published in July 2010

Host defense peptides: roles and applications

scientific article published on 01 February 2005

Human beta-defensin 2 induces a vigorous cytokine response in peripheral blood mononuclear cells

scientific article

Identification and characterization of a primary antibacterial domain in CAP18, a lipopolysaccharide binding protein from rabbit leukocytes.

scientific article

Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin

scientific article published in February 2005

Identification of antimicrobial peptides from teleosts and anurans in expressed sequence tag databases using conserved signal sequences

scientific article

Inhibition of OH radical-induced strand break formation of poly(U) by Ru(bpy)32+ or Ru(phen)32+ attached to the polynucleotide

scientific article published on 01 November 1995

Inhibition of cathelicidin activity by bacterial exopolysaccharides

scientific article published on 21 April 2009

Interaction of ruthenium complexes with nucleic acids. DNA damage via photosensitized radical production

scientific article published on 01 January 1989

Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides ⬇️

scientific article published on January 28, 2011

Mammalian defensins: structures and mechanism of antibiotic activity.

scientific article

Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge

scientific article published on 01 May 2008

Molecular diversity in gene-encoded, cationic antimicrobial polypeptides.

scientific article

Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.).

scientific article

Native oligomerization determines the mode of action and biological activities of human cathelicidin LL-37

scientific article published on 01 January 2014

New aspects of the structure and mode of action of the human cathelicidin LL-37 revealed by the intrinsic probe p-cyanophenylalanine.

scientific article published in February 2015

Overview on plant antimicrobial peptides.

scientific article published on May 2010

PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity.

scientific article

Photoaddition of ruthenium(II)-tris-1,4,5,8-tetraazaphenanthrene to DNA and mononucleotides.

scientific article published on April 1994

Photoinduced interaction of Ru(bpy)3 2+ with nucleotides and nucleic acids in the presence of S2O8 2-; a transient conductivity study.

scientific article published on February 1993

Primate cathelicidin orthologues display different structures and membrane interactions

scientific article published on 01 February 2009

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action.

scientific article published on 19 May 2011

Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization

scientific article published on 23 June 2019

Role of Cathelicidin Peptides in Bovine Host Defense and Healing

scientific article published in March 2010

Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences.

scientific article published on 27 November 2012

Site-specific photocleavage of DNA

scientific article published on 01 September 1990

Small hydroxyethylene-based peptidomimetics inhibiting both HIV-1 and C. albicans aspartic proteases.

scientific article published in November 2003

Solid-phase synthesis of fullerene-peptides

scientific article published in October 2002

Stereoselective synthesis of non symmetric dihydroxyethylene dipeptide isosteres via epoxyalcohols derived from α-amino acids

scientific article published on 01 October 1999

Structural aspects and biological properties of the cathelicidin PMAP-36

article

Structure Based Design of Inhibitors of Aspartic Protease of HIV-1

article

Structuring and interactions of human beta-defensins 2 and 3 with model membranes.

scientific article published in April 2008

Substrate specificity of CDC2 kinase from human HeLa cells as determined with synthetic peptides and molecular modeling

scientific article published on 01 December 1994

Synthesis and biological activity of potent HIV-1 protease inhibitors based on Phe-Pro dihydroxyethylene isosteres

scientific article published on 17 April 2012

The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.

scientific article published on 02 September 2008

The human cathelicidin LL-37--A pore-forming antibacterial peptide and host-cell modulator

scientific article

The non-peptidic HIV protease inhibitor tipranavir and two synthetic peptidomimetics (TS98 and TS102) modulate Pneumocystis carinii growth and proteasome activity of HEL299 cell line

scientific article published on January 2006

Tuning the biological properties of amphipathic alpha-helical antimicrobial peptides: rational use of minimal amino acid substitutions

scientific article published on 6 June 2005

Use of unnatural amino acids to probe structure-activity relationships and mode-of-action of antimicrobial peptides

scientific article published on 01 January 2012

Versatile and Stereoselective Synthesis of Diamino Diol Dipeptide Isosteres, Core Units of Pseudopeptide HIV Protease Inhibitors

article

Wide-spectrum antibiotic activity of synthetic, amphipathic peptides.

scientific article published on August 1998

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