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List of works by Janet Rowley

"Microgranular" acute promyelocytic leukemia: a distinct clinical, ultrastructural, and cytogenetic entity

scientific article published on 01 February 1980

11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

scientific article published in October 1994

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

scientific article published on 01 March 1977

2002 William Allen Award address. Introductory speech for Albert de la Chapelle

scientific article

A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration

scientific article published on 01 September 1985

A Burkitt-lymphoma variant translocation (2p-; 8q+) in a patient with ALL, L3 (Burkitt type)

scientific article published on 01 January 1981

A Morphologic and Cytochemical Study of Acute Myelomonocytic Leukemia with Abnormal Marrow Eosinophils Associated with Inv(16)(p13q22) ⬇️

scientific article published on 01 June 1984

A balanced translocation (17;22) and a pericentric inversion of chromosome 5. Repository identification No. GM3196.

scientific article published on January 1980

A chromosome marker for B-cell cancer

scientific article published on 01 June 1978

A collaborative study of the relationship of the morphological type of acute nonlymphocytic leukemia with patient age and karyotype

scientific article published on 01 May 1982

A complex genetic rearrangement in a t(10;14)(q24;q11) associated with T-cell acute lymphoblastic leukemia

scientific article published on January 1, 1992

A method for the rapid sequence-independent amplification of microdissected chromosomal material

scientific article published on August 1, 1992

A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome

scientific article published on September 2002

A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis

scientific article published on 30 July 2006

A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia

scientific article published on October 1988

A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15.

scientific article

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

scientific article

AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12)

scientific article

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

scientific article

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

scientific article

Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival

scientific article published on 01 November 1995

Acute Monocytic Leukemia: Cytologic, Histologic, Cytochemical, Ultrastructural, and Cytogenetic Observations ⬇️

scientific article published on April 1, 1976

Acute leukemia after treatment of lymphoma

scientific article published on 01 November 1977

Acute megakaryoblastic leukemia in Down's syndrome: report of a case and review of cytogenetic findings

scientific article published on January 1985

Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis

scientific article published on 01 December 1986

Acute nonlymphocytic leukemia in adults: correlations with Q-banded chromosomes

scientific article published on July 1, 1976

Acute nonlymphocytic leukemia in malignant lymphoma.A morphologic study ⬇️

scientific article published on July 1, 1978

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders ⬇️

scientific article published on July 15, 1997

An (8;14)(q24;q11) translocation involving the T-cell receptor alpha-chain gene and the MYC oncogene 3' region in a B-cell lymphoma

scientific article published on 01 September 1989

An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

scientific article published on 01 November 1998

Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization

scientific article published on December 1993

Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line

scientific article

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements

scientific article published in December 2004

Analysis of tumor suppressor gene on human chromosome 9 in mouse x human somatic cell hybrids

scientific article published on September 1994

Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders

scientific article

Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders

scientific article published on 01 January 1986

Assignment of the human GDID4 gene, a GDP/GTP-exchange regulator, to chromosome 12p12.3

scientific article (publication date: November 1994)

Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias

scientific article published on 01 March 1995

Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia

scientific article published on 01 November 1987

Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association

scientific article published on 01 September 1983

Association of red cell spherocytosis with deletion of the short arm of chromosome 8

scientific article published on 01 January 1987

Associations between morphology, karyotype, and clinical features in myeloid leukemias.

scientific article

B cell acute lymphoblastic leukemia (ALL) with a 14q+ chromosome abnormality ⬇️

scientific article published on February 1, 1979

BCL3 rearrangements and t(14;19) in chronic lymphocytic leukemia and other B-cell malignancies: A molecular and cytogenetic study ⬇️

scientific article published on September 1, 1997

Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia ⬇️

scientific article published on 01 April 1992

Banding studies of chromosomal abnormalities in patients with acute lymphocytic leukemia ⬇️

scientific article published on January 1, 1979

Banding studies of chromosomes in a patient with mycosis fungoides

scientific article published on 01 November 1978

Banding studies on chromosomes in diffuse "histiocytic" lymphomas: correlation of 14q+ marker chromosome with cytology ⬇️

scientific article published on November 1, 1978

CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy ⬇️

scientific article published on October 15, 1998

Cancer biology: Heritable fragile sites in cancer

scientific article published in Nature

Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16).

scientific article

Chromatin structural elements and chromosomal translocations in leukemia

scientific article published on 7 August 2006

Chromosomal DNA cytophotometry in 20q- nonspecific myeloid disorders ⬇️

scientific article published on August 1, 1979

Chromosomal Translocations in Secondary Acute Myeloid Leukemia

scientific article published on 01 February 1996

Chromosomal abnormalities in leukemia and lymphoma: clinical and biological significance

scientific article published on January 1986

Chromosomal aneuploidy in a patient with hypereosinophilic syndrome. Evidence for a malignant disease

scientific article published on December 1977

Chromosomal banding patterns in acute nonlymphocytic leukemia ⬇️

scientific article published on 01 May 1976

Chromosomal instability in chromosome band 12p13: multiple breaks leading to complex rearrangements including cytogenetically undetectable sub-clones.

scientific article

Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia

scientific article published on December 1985

Chromosomal localization of the human G-CSF gene to 17q11 proximal to the breakpoint of the t(15;17) in acute promyelocytic leukemia

scientific article

Chromosomal localization of the human T cell receptor beta-chain genes

scientific article published on 01 May 1985

Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders ⬇️

scientific article published on March 15, 1992

Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia

scientific article published on 01 April 1989

Chromosomal sublocalization of the human p97 melanoma antigen

scientific article

Chromosomal translocations: revisited yet again

scientific article published on September 2008

Chromosome 14 translocations in non-burkitt lymphomas ⬇️

scientific article published on July 15, 1978

Chromosome abnormalities in B cell chronic lymphocytic leukemia and their clinical correlations

scientific article published in March 1989

Chromosome abnormalities in Down's syndrome patients with acute leukemia

scientific article published on September 1981

Chromosome abnormalities in patients with hairy cell leukemia ⬇️

scientific article published on April 1, 1978

Chromosome abnormalities in poorly differentiated lymphocytic lymphoma ⬇️

scientific article published on 01 August 1979

Chromosome abnormalities in tumor cells from patients with sporadic Wilms' tumor

scientific article published on November 1984

Chromosome changes in hematologic malignancies.

scientific article published on July 1981

Chromosome pattern in childhood acute nonlymphocytic leukemia (ANLL)

scientific article published on 01 August 1982

Chromosomes and causation of human cancer and leukemia. XXXV. The missing Y in acute non-lymphocytic leukemia (ANLL).

scientific article published on January 1980

Chromosomes in leukemia and beyond: from irrelevant to central players

scientific article

Chronic Myeloid Leukemia: Current Perspectives ⬇️

scientific article published on October 14, 2011

Chronic myelodysplastic syndrome (preleukemia) with the Philadelphia chromosome

scientific article published on 01 August 1980

Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7

scientific article

Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia ⬇️

scientific article published on 01 December 1992

Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11)

scientific article published on 01 July 1990

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

scientific article

Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia

scientific article published on January 1989

Clonal, nonconstitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: in utero chromosome rearrangement of 11q23

scientific article published on 01 February 1994

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

scientific article

Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations ⬇️

scientific article published on December 15, 1992

Cloning of the breakpoint junction of the translocation 14;19 in chronic lymphocytic leukemia

scientific article published on 01 January 1989

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions ⬇️

scientific article published on October 11, 1994

Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia

scientific article

Comparable complex rearrangements involving 8;21 and 9;22 translocations in leukaemia ⬇️

scientific article published on April 21, 1977

Comparative gene mapping in cattle, Indian muntjac, and Chinese muntjac by fluorescence in situ hybridization

scientific article published on 19 February 2008

Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias

scientific article published on 20 January 2009

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

scientific article

Constitutional t(15;17): clarification of the chromosomal breakpoints

scientific article

Correct identification of genes from serial analysis of gene expression tag sequences

scientific article published on 01 April 2002

Correlation between cell morphology and expression of the AML1/ETO chimeric transcript in patients with acute myeloid leukemia without the t(8;21)

scientific article published on 01 September 1994

Correlation between the ETV6/CBFA2 (TEL/AML1) fusion gene and karyotypic abnormalities in children with B-cell precursor acute lymphoblastic leukemia

scientific article published on 01 October 1996

Correlation of clinical findings with quinacrine-banded chromosomes in 90 adults with acute nonlymphocytic leukemia: an eight-year study (1970-1977).

scientific article

Correlation of karyotype with clinical features in acute lymphoblastic leukemia

scientific article published on 01 July 1982

Correlation of occupation and karyotype in adults with acute nonlymphocytic leukemia.

scientific article published in August 1982

Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis ⬇️

scientific article published on March 18, 2013

Culture conditions in chronic lymphocytic leukemia: relationship to karyotype

scientific article published on 01 March 1989

Cytogenetic analysis of 51 patients with chronic myeloid leukemia

scientific article published in October 1990

Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation

scientific article

Cytogenetic and molecular analysis of therapy-related leukemia

scientific article

Cytogenetic and molecular study of the PRDX4 gene in a t(X;18)(p22;q23): a cautionary tale

scientific article

Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors ⬇️

scientific article published on September 1, 1992

Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion

scientific article published on 01 March 1993

Cytogenetic studies in patients with hairy cell leukemia

scientific article published on 01 July 1983

Cytogenetic studies of 21 patients with acute lymphoblastic leukemia in relapse

scientific article

Cytogenetic studies on patients with chronic T cell leukemia/lymphoma

scientific article

DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation

scientific article published on March 1994

DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis

scientific article

Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells

scientific article

Deletion of the long arm of chromosome 20 [del(20)(q11)] in myeloid disorders ⬇️

scientific article published on 01 November 1978

Deletions of Interferon Genes in Acute Lymphoblastic Leukemia

article

Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.

scientific article published on August 1995

Detection of 9p deletions in leukemia cell lines by interphase fluorescence in situ hybridization with YAC-derived probes

scientific article published on 01 August 1995

Detection of DNA rearrangements in the AML1 and ETO loci and of an AML1/ETO fusion mRNA in patients with t(8;21) acute myeloid leukemia

scientific article published on February 1993

Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study

scientific article published on 01 November 1994

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia

scientific article published on 01 April 1994

Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method ⬇️

scientific article published on 01 April 1992

Development of dysmyelopoietic syndrome in a hairy cell leukemia patient treated with chlorambucil: cytogenetic and morphologic evaluation

scientific article published on 01 February 1983

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

scientific article

Differential expression of TCL1 during pre-B-cell acute lymphoblastic leukemia progression

scientific article (publication date: June 2002)

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

scholarly article

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

scientific article published on 01 March 1996

Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization ⬇️

scientific article published on 01 August 1993

Duplexes of 21‐nucleotide RNAs mediate RNA interference in differentiated mouse ES cells ⬇️

scientific article published on September 1, 2003

Dysmyelopoietic syndrome: sequential clinical and cytogenetic studies.

scientific article published in April 1980

Establishment and characterization of a megakaryoblast cell line with amplification of MLL ⬇️

scientific article published on July 1, 1998

Establishment, characterization and differentiation induction of a new human diploid myelomonocytic cell line (HL-92) derived from a patient with acute myelomonocytic leukemia

scientific article

Evaluation of techniques for increasing mitotic yield and chromosome length in leukemic cells

scientific article published on November 1984

Evidence favoring lineage fidelity in acute nonlymphocytic leukemia: absence of immunoglobulin gene rearrangements in FAB types M4 and M5

scientific article published on 01 January 1987

Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemia

article

Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders

scientific article

Evidence for two distinct c-src loci on human chromosomes 1 and 20 ⬇️

scientific article published on November 1, 1984

Evolution of karyotypes in acute nonlymphocytic leukemia ⬇️

scientific article published on September 1, 1979

Evolution of karyotypes in philadelphia (Ph1) chromosome-negative chronic myelogenous leukemia ⬇️

scientific article published on February 1, 1979

Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases.

scientific article published on November 1994

Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

scientific article

Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in defining abnormalities associated with poor prognosis.

scientific article published in July 2001

Further chromosome studies on Wilms' tumor cells of patients without aniridia ⬇️

scientific article published on 01 October 1983

Further evidence for a non-random chromosomal abnormality in acute promyelocytic leukemia ⬇️

scientific article published on December 15, 1977

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

scientific article

Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia

scientific article published on May 1986

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

scientific article published on 17 January 2006

Generation of Longer cDNA Fragments from SAGE Tags for Gene Identification

scientific article published on 01 January 2003

Genetics. A story of swapped ends

scientific article

Genome-wide analysis of coordinate expression and evolution of human cis-encoded sense-antisense transcripts

scientific article published on 01 June 2005

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

scientific article

Hairy cell leukemia: An analysis of the chromosomes of 26 patients ⬇️

scientific article published on November 17, 1978

Harmful moratorium on stem cell research

scientific article published in September 2002

Have skills, will travel

scientific article published on 01 January 2012

Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6 ) is involved in only one half ⬇️

scientific article published on December 15, 1997

Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization

scientific article published on 01 July 1993

Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping

scientific article published on April 1997

Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines

scientific article

Hu-ets-2 is translocated to chromosome 8 in the t(8;21) in acute myelogenous leukemia

scientific article

Human T-cell lymphoma with suppressor effects on the mixed lymphocyte reaction (MLR). I. Morphological and cytogenetic analysis.

scientific article

Human antisense genes have unusually short introns: evidence for selection for rapid transcription

article

Hypercalcemia and Lytic Bone Lesions in a Patient with B-Cell Non-Hodgkin's Lymphoma ⬇️

scientific article published on January 26, 1984

Hyperdiploidy arising from near-haploidy in childhood acute lymphoblastic leukemia

scientific article published on 01 June 1992

Hypergranular promyelocytic leukemia (APL): cytogenetic and ultrastructural specificity ⬇️

scientific article published on August 1, 1978

ISCN (2005) is not acceptable for describing clonal evolution in cancer

scientific article published on 01 March 2007

Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia

scientific article

Identification of a 1.2 Kb cDNA fragment from a region on 9p21 commonly deleted in multiple tumor types

scientific article (publication date: September 2001)

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study

scientific article published on 4 February 2013

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias ⬇️

scientific article published on December 1, 1991

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells

scientific article

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt ⬇️

scientific article (publication date: October 1992)

Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia

scientific article published on October 1, 1997

Identification of cytogenetically undetected 12p13 translocations and associated deletions with fluorescence in situ hybridization

scientific article published on 01 January 1995

Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6)

scientific article published on 01 September 1997

Identifying novel transcripts and novel genes in the human genome by using novel SAGE tags

scientific article

Idiopathic Acquired Refractory Sideroblastic Anemia: Banded Chromosome Analysis in Six Patients ⬇️

scientific article published on January 1, 1977

Increased karyotype precision using fluorescence in situ hybridization and spectral karyotyping in patients with myeloid malignancies

scientific article published on 01 January 1999

Increased numbers of marrow basophils may be associated with a t(6;9) in ANLL.

scientific article published in April 1985

Insertion (10;11)(p11;q23q24) in two cases of acute monocytic leukemia

scientific article published on 01 January 1985

Interferon and c-ets-1 genes in the translocation (9;11)(p22;q23) in human acute monocytic leukemia

scientific article published on 01 January 1986

Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family

scientific article

Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).

scientific article published in February 1989

International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview report

scientific article published on 01 April 2002

Interstitial deletion of short arm of chromosome 11 limited to Wilms' tumor cells in a patient without aniridia ⬇️

scientific article published on 01 November 1981

Involvement of the AML1 gene in the t(3;21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis

scientific article published on 01 May 1993

Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated

scientific article published on January 1985

Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia

scientific article

Karyotypic abnormalities and clinical aspects of patients with multiple myeloma and related paraproteinemic disorders ⬇️

scientific article published on August 1, 1979

Karyotypic patterns and their clinical significance in polycythemia vera

scientific article published on 01 January 1981

Knockdown of Pu.1 by small interfering RNA in CD34+ embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells

scientific article

Leukaemogenesis: more than mutant genes

scientific article

Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph+ acute lymphoblastic leukemia.

scientific article

Lineage specificity of CBFA2 fusion transcripts

scientific article

Local gene density predicts the spatial position of genetic loci in the interphase nucleus

article

Localization of the oncogene c-erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17

scientific article published on 01 July 1985

Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis.

scientific article published in March 1988

Long-term survival of patients with acute myeloid leukemia: a third follow-up of the Fourth International Workshop on Chromosomes in Leukemia

scientific article published on 01 December 1997

Lymphoblastic leukemia with lymphomatous features associated with abnormalities of the short arm of chromosome 9

scientific article published on 01 August 1985

Lymphoblastic lymphoma in adults

scientific article published on 01 May 1981

Lymphoblastic lymphoma: cytogenetic, pathologic, and immunologic studies

scientific article published on 01 September 1982

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3) ⬇️

scientific article published on August 5, 1997

MLL is involved in a t(2;11)(p21;q23) in a patient with acute myeloblastic leukemia

scientific article published on 01 February 1999

Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome

scientific article

Medicine. The cart before the horse

scientific article published on September 2008

Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia

scientific article

Methods for the analysis of human chromosome aberrations

Methods of processing marrow samples may affect the frequency of detectable aneuploid cells ⬇️

scientific article published on 01 December 1981

Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16)

scientific article published on 01 February 2007

MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

scientific article

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

scholarly article

Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells

scientific article

Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia

scientific article

Molecular analysis of a t(11;14)(q23;q11) from a patient with null‐cell acute lymphoblastic leukemia ⬇️

scientific article published on May 1, 1993

Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas

scientific article published in May 1992

Molecular analysis of the Mono Mac 6 cell line: detection of an MLL-AF9 fusion transcript

scientific article published on 01 February 1995

Molecular analysis of the T-cell acute lymphoblastic leukemia-associated t(1;7)(p34;q34) that fuses LCK and TCRB.

scientific article published on August 1994

Molecular analysis of the t(8;14)(q24;q11) chromosomal breakpoint junctions in the T-cell leukemia line MOLT-16

scientific article published on December 1, 1997

Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis.

scientific article published on February 1995

Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC.

scientific article published on September 1986

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure

scientific article

Molecular cytogenetic characterization of breakpoints in 19 patients with hematologic malignancies and 12p unbalanced translocations

scientific article published on 01 April 2003

Molecular portraits of B cell lineage commitment

scientific article

Morphologic and Cytochemical Observations on the Overt Leukemic Phase of Therapy-related Leukemia ⬇️

scientific article published on 01 May 1983

Multiple cytogenetically abnormal clones in two polycythemia vera patients ⬇️

scientific article published on 01 January 1981

Myeloid leukemia after hematotoxins

scientific article

New Fusion Transcripts Identified in Normal Karyotype Acute Myeloid Leukemia ⬇️

scientific article published on December 12, 2012

Nonrandom chromosome abnormalities in acute leukemia and dysmyelopoietic syndromes in patients with previously treated malignant disease

scientific article

Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy ⬇️

scientific article published on October 1, 1982

Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription

scientific article

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

scientific article

Over 20% of human transcripts might form sense-antisense pairs

scientific article published in 2004

PBX3 is an important cofactor of HOXA9 in leukemogenesis

scientific article published on 20 December 2012

PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).

scientific article published in August 2004

Partial deletion of long arm of chromosome 17: a specific abnormality in acute promyelocytic leukemia?

scientific article published on 01 July 1976

Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission.

scientific article

Philadelphia Chromosome Symposium: commemoration of the 50th anniversary of the discovery of the Ph chromosome ⬇️

scientific article published on April 1, 2011

Philadelphia chromosome-negative chronic myelogenous leukaemia: a morphological reassessment

scientific article

Planning the Genome Institute's Future

scientific article published in Science

Polymorphisms in the MLL breakpoint cluster region (BCR)

scientific article published on 29 March 2003

Prognostic implications of karyotype and morphology in patients with non-Hodgkin's lymphoma

scientific article published in December 1983

Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes

scientific article published on 01 June 1986

Prognostic significance of posttransfusion hepatitis and chromosomal abnormalities in adult acute nonlymphocytic leukemia

scientific article published on 01 April 1982

Prognostic significance of the AML1-ETO fusion transcript expression in children and young adults with t(8;21) acute myeloid leukemia

scientific article published on 01 September 2003

RETRACTED: Silencing of B cell receptor signals in human naive B cells

retracted scientific article

Re: G. Cimino et al., Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations. Cancer Res., 51: 6712-6714, 1991 ⬇️

scientific article published on May 15, 1992

Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.

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Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia

Rearrangements of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: in vitro and in vivo studies

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Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II

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Reason as our guide

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Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

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Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings ⬇️

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Retraction

Scaffold attachment regions in centromere-associated DNA

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Scaffold-Associated Regions in the Human Type I Interferon Gene Cluster on the Short Arm of Chromosome 9 ⬇️

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Screening Poly [dA/dT(-)] cDNA for Gene Identification

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Screening and quantification of multiple chromosome translocations in human leukemia

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Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization

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Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine

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Significance of cytogenetic abnormalities in acute leukemias

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Six-year follow-up of the clinical significance of karyotype in acute lymphoblastic leukemia

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Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo

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Spectral karyotype analysis of T-cell acute leukemia

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

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T lymphoid differentiation in human bone marrow ⬇️

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T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).

scientific article published on December 1986

TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies ⬇️

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TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines

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TET1 plays an essential oncogenic role in MLL-rearranged leukemia

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Targeting mutations predictably ⬇️

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The 14q+ chromosome in pre-B-ALL

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The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

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The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2.

scientific article published on November 1991

The Leukemic Phase of Histiocytic Lymphoma: Histologic, Cytologic, Cytochemical, Ultrastructural, Immunologic and Cytogenetic Observations in a Case ⬇️

scientific article published on May 1, 1978

The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.

scientific article published on February 1996

The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing

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The human met oncogene is related to the tyrosine kinase oncogenes

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The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q

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The leukemia-associated gene MDS1/EVI1 is a new type of GATA-binding transactivator

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The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin

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The mixed lineage leukemia (MLL) protein involved in 11q23 translocations contains a domain that binds cruciform DNA and scaffold attachment region (SAR) DNA.

scientific article published on January 1996

The molecular biology of myeloproliferative disorders as revealed by chromosomal abnormalities.

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The pattern and clinical significance of karyotypic abnormalities in patients with idiopathic and postpolycythemic myelofibrosis

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The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: A 12-year study (1970–1982)

scientific article published on 01 November 1983

The proportion of abnormal karyotypes in acute leukemia samples related to method of preparation

scientific article published on 01 March 1991

The relationship between secondary chromosomal abnormalities and blast transformation in chronic myelogenous leukemia

scientific article published on 01 April 1995

The role of the c-mos gene in the 8;21 translocation in human acute myeloblastic leukemia

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The small introns of antisense genes are better explained by selection for rapid transcription than by "genomic design"

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The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

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The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

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The transcriptome of human CD34+ hematopoietic stem-progenitor cells

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The use of methylthioadenosine phosphorylase activity to select for human chromosome 9 in interspecies and intraspecies hybrid cells

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Therapy-related acute leukemia associated with t(11q23) after primary acute myeloid leukemia with t(8;21): a report of two cases ⬇️

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Therapy-related acute myeloid leukemia/myelodysplasia with balanced 21q22 translocations

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Therapy-related myelodysplastic syndrome and acute myeloid leukemia in children: correlation between chromosomal abnormalities and prior therapy

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Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia

scientific article published on 01 August 1985

Trisomy 8 in human hematologic neoplasia and the c-myc and c-mos oncogenes

Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia

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U937 cell line has a t(I0;II)(pI3–I4;qI4–2I) rather than a deletion of IIq ⬇️

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Undetected chromosome abnormalities in leukemia: a cautionary note

scientific article published on 01 April 1981

Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia

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Unique balanced chromosome abnormalities in treatment-related myelodysplastic syndromes and acute myeloid leukemia: report from an international workshop

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Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

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Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization

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Variant three-way translocation of inversion 16 in AML-M4Eo confirmed by fluorescence in situ hybridization analysis.

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Variant translocations (9;11): identification of the critical genetic rearrangement

scientific article published on 01 January 1988

c-src is consistently conserved in the chromosomal deletion (20q) observed in myeloid disorders

scientific article published on October 1985

der(5)t(5;7)(q11.2;p11.2): A new recurring abnormality in malignant myeloid disorders

scientific article published on 01 January 1989

miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.

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t(1;3)(p36;p21) is a recurring therapy-related translocation

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t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia

scientific article published in December 1990

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