List of works - Gilles Lalmanach

A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi

scientific article published on 01 September 1997

A new, sensitive fluorogenic substrate for papain based on the sequence of the cystatin inhibitory site

scientific article published on 01 November 1993

A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate

scientific article published on 24 December 2011

A virus essential for insect host-parasite interactions encodes cystatins.

scientific article

Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids

scientific article

Active site labeling of cysteine cathepsins by a straightforward diazomethylketone probe derived from the N-terminus of human cystatin C.

scientific article

Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development ⬇️

scientific article

An immunochemical approach to investigating the mechanism of inhibition of cysteine proteinases by members of the cystatin superfamily.

scientific article

Antimicrobial proteins and peptides in human lung diseases: A friend and foe partnership with host proteases.

scientific article published on 02 September 2015

Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity

scientific article published on 4 September 2013

CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells

scientific article published in July 2002

Cathepsin L, but not cathepsin B, is a potential kininogenase

scientific article published in May 2001

Chicken cystatin stimulates nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages via cytokine synthesis

scientific article published on 01 December 1999

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

scientific article published on 25 September 2019

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

scientific article

Congopain from Trypanosoma congolense: drug target and vaccine candidate.

scientific article

Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases

scientific article published on 01 November 1995

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

scientific article published in Scientific Reports

Cystatin mimicry by synthetic peptides

scientific article published on July 1, 1992

Cystatins up-regulate nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages

scientific article published on 01 November 1996

Cysteine cathepsins and caspases in silicosis.

scientific article published on July 2006

Cysteine cathepsins and cystatins: from ancillary tasks to prominent status in lung diseases.

scientific article published on February 2015

Cysteine cathepsins in human silicotic bronchoalveolar lavage fluids

scientific article

Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

scientific article

Degradation of apolipoprotein B-100 by lysosomal cysteine cathepsins.

scientific article

Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis

scientific article

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis.

scientific article published on 22 September 2016

Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases

scientific article published on 01 January 1999

Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella

scientific article

Evaluation of a peptide ELISA for the detection of rituximab in serum.

scientific article published on 17 July 2007

Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide.

scientific article

Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

scientific article

Human cystatin C: a new biomarker of idiopathic pulmonary fibrosis?

scientific article published on 25 November 2013

Human cysteine cathepsins are not reliable markers of infection by Pseudomonas aeruginosa in cystic fibrosis

scientific article

Identification of parasite-responsive cysteine proteases in Manduca sexta.

scientific article published on May 2009

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

scientific article published on 23 March 2019

Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targetting the disease rather than the parasite

scientific article

Inhibition of a cathepsin L-like cysteine protease by a chimeric propeptide-derived inhibitor

scientific article published in August 2005

Inhibition of cathepsin B by its propeptide: use of overlapping peptides to identify a critical segment

scientific article published on 01 September 1996

Inhibition of trypanosomal cysteine proteinases by their propeptides.

scientific article

Interaction between cystatin-derived peptides and papain

scientific article published on 01 February 1993

Kininogen-derived peptides for investigating the putative vasoactive properties of human cathepsins K and L.

scientific article

Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe

scientific article

Lung cysteine cathepsins: intruders or unorthodox contributors to the kallikrein-kinin system?

scientific article

Modulation of hypotensive effects of kinins by cathepsin K.

scientific article published on 9 November 2006

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

scientific article published on 16 February 2016

Oxidation of cathepsin S by major chemicals of cigarette smoke

scientific article published on 19 February 2020

Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degrada

scientific article published on 01 January 2003

Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor.

scientific article

Probing cathepsin K activity with a selective substrate spanning its active site.

scientific article published in October 2003

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

scientific article published on 25 September 2019

Procongopain from Trypanosoma congolense is processed at basic pH: an unusual feature among cathepsin L-like cysteine proteases.

scientific article published in June 2003

Protean proteases: at the cutting edge of lung diseases

scientific article published on 8 February 2017

Proteases in the limelight: Both ordinary digestive enzymes and smart signaling pathway regulators

scientific article published on 18 January 2016

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

scientific article

Proteolytic enzymes: from structures to transport pathways

scientific article published on 19 November 2007

Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

scientific article published on 15 November 2019

Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.

scientific article

Regulation of cathepsin K activity by hydrogen peroxide

scientific article

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

scientific article published on 12 March 2020

Reversible inhibition of cathepsin L-like proteases by 4-mer pseudopeptides

scientific article

Revisiting the S2 specificity of papain by structural analogs of Phe

scientific article published on 01 February 1999

Selective inhibition of human cathepsin S by 2,4,6-trisubstituted 1,3,5-triazine analogs

scientific article published on 19 July 2018

Selective inhibition of the collagenase activity of cathepsin K

scientific article published on 10 April 2007

Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties

scientific article published on 22 May 2013

Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S.

scientific article published on 6 May 2016

Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids

scientific article published in May 2001

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.

scientific article published on 7 December 2017

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

scientific article

The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

scientific article

The occluding loop of cathepsin B prevents its effective inhibition by human kininogens.

scientific article published on 9 June 2010

Therapeutic targeting of cathepsin C: from pathophysiology to treatment

scientific article published on 26 May 2018

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

scientific article published on 28 January 2009

What's up in the proteolysis landscape? A lively blend of classical concepts and pioneering innovations

scientific article published on 02 October 2019

Yin and Yang in the proteolytic landscape

scientific article published in November 2010

List of works by Gilles Lalmanach

A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi

A new, sensitive fluorogenic substrate for papain based on the sequence of the cystatin inhibitory site

A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate

A virus essential for insect host-parasite interactions encodes cystatins.

Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids

Active site labeling of cysteine cathepsins by a straightforward diazomethylketone probe derived from the N-terminus of human cystatin C.

Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development ⬇️

An immunochemical approach to investigating the mechanism of inhibition of cysteine proteinases by members of the cystatin superfamily.

Antimicrobial proteins and peptides in human lung diseases: A friend and foe partnership with host proteases.

Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity

CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells

Cathepsin L, but not cathepsin B, is a potential kininogenase

Chicken cystatin stimulates nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages via cytokine synthesis

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

Congopain from Trypanosoma congolense: drug target and vaccine candidate.

Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Cystatin mimicry by synthetic peptides

Cystatins up-regulate nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages

Cysteine cathepsins and caspases in silicosis.

Cysteine cathepsins and cystatins: from ancillary tasks to prominent status in lung diseases.

Cysteine cathepsins in human silicotic bronchoalveolar lavage fluids

Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

Degradation of apolipoprotein B-100 by lysosomal cysteine cathepsins.

Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis.

Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases

Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella

Evaluation of a peptide ELISA for the detection of rituximab in serum.

Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide.

Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

Human cystatin C: a new biomarker of idiopathic pulmonary fibrosis?

Human cysteine cathepsins are not reliable markers of infection by Pseudomonas aeruginosa in cystic fibrosis

Identification of parasite-responsive cysteine proteases in Manduca sexta.

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targetting the disease rather than the parasite

Inhibition of a cathepsin L-like cysteine protease by a chimeric propeptide-derived inhibitor

Inhibition of cathepsin B by its propeptide: use of overlapping peptides to identify a critical segment

Inhibition of trypanosomal cysteine proteinases by their propeptides.

Interaction between cystatin-derived peptides and papain

Kininogen-derived peptides for investigating the putative vasoactive properties of human cathepsins K and L.

Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe

Lung cysteine cathepsins: intruders or unorthodox contributors to the kallikrein-kinin system?

Modulation of hypotensive effects of kinins by cathepsin K.

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

Oxidation of cathepsin S by major chemicals of cigarette smoke

Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degrada

Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor.

Probing cathepsin K activity with a selective substrate spanning its active site.

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

Procongopain from Trypanosoma congolense is processed at basic pH: an unusual feature among cathepsin L-like cysteine proteases.

Protean proteases: at the cutting edge of lung diseases

Proteases in the limelight: Both ordinary digestive enzymes and smart signaling pathway regulators

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

Proteolytic enzymes: from structures to transport pathways

Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.

Regulation of cathepsin K activity by hydrogen peroxide

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Reversible inhibition of cathepsin L-like proteases by 4-mer pseudopeptides

Revisiting the S2 specificity of papain by structural analogs of Phe

Selective inhibition of human cathepsin S by 2,4,6-trisubstituted 1,3,5-triazine analogs

Selective inhibition of the collagenase activity of cathepsin K

Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties

Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S.

Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

The occluding loop of cathepsin B prevents its effective inhibition by human kininogens.

Therapeutic targeting of cathepsin C: from pathophysiology to treatment

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

What's up in the proteolysis landscape? A lively blend of classical concepts and pioneering innovations

Yin and Yang in the proteolytic landscape