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List of works by Michael Milosevic

A Practice-based Taxonomy for Radiation Treatment Errors

scientific article published in December 2013

A cinematic magnetic resonance imaging study of milk of magnesia laxative and an antiflatulent diet to reduce intrafraction prostate motion

scientific article

A comparison of dynamic contrast-enhanced CT and MR imaging-derived measurements in patients with cervical cancer

scientific article published on 27 November 2012

A facility for magnetic resonance-guided radiation therapy

scientific article

A final report of a phase I study of veliparib (ABT-888) in combination with low-dose fractionated whole abdominal radiation therapy (LDFWAR) in patients with advanced solid malignancies and peritoneal carcinomatosis with a dose escalation in ovaria

scientific article

A hypofractionated radiotherapy regimen (0-7-21) for advanced gynaecological cancer patients

scientific article

A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors

scientific article (publication date: 2013)

A method for patient dose reduction in dynamic contrast enhanced CT study

scientific article published in September 2011

A phase II study of localized prostate cancer treated to 75.6Gy with 3D conformal radiotherapy

scientific article published on 01 July 2005

A phase III randomized study of misonidazole plus radiation vs. radiation alone for cervix cancer

scientific article published in March 2004

A prospective phase I–II trial of the cyclooxygenase-2 inhibitor celecoxib in patients with carcinoma of the cervix with biomarker assessment of the tumor microenvironment

scientific article published on 23 October 2006

A prospective study of DWI, DCE-MRI and FDG PET imaging for target delineation in brachytherapy for cervical cancer

scientific article published on 12 August 2016

A randomized comparison of interfraction and intrafraction prostate motion with and without abdominal compression

scientific article published on 14 February 2008

A randomized trial of supine vs. prone positioning in patients undergoing escalated dose conformal radiotherapy for prostate cancer

article

Accelerated radiation therapy for primary lymphoma of the brain

scientific article published in May 1998

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer

scientific article published on 27 December 2011

An integrated approach to segmentation and nonrigid registration for application in image-guided pelvic radiotherapy.

scientific article

Anatomic boundaries of the clinical target volume (prostate bed) after radical prostatectomy.

scientific article published on November 2007

Androgen Withdrawal in Patients Reduces Prostate Cancer Hypoxia: Implications for Disease Progression and Radiation Response

scientific article published on 01 July 2007

Appropriate radiation volume for stage IIA/B testicular seminoma

scientific article published on 01 July 2003

Assessment of the tumor microenvironment in cervix cancer using dynamic contrast enhanced CT, interstitial fluid pressure and oxygen measurements

article

Association between Metformin Use and Mortality after Cervical Cancer in Older Women with Diabetes.

scientific article published on 31 December 2015

Association of Apparent Diffusion Coefficient with Disease Recurrence in Patients with Locally Advanced Cervical Cancer Treated with Radical Chemotherapy and Radiation Therapy

scientific article published on 27 October 2015

Automated Delineation of the Normal Urinary Bladder on Planning CT and Cone Beam CT

scientific article published on 18 November 2015

Automated Weekly Replanning for Intensity-Modulated Radiotherapy of Cervix Cancer

scientific article published on 01 October 2010

Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy.

scientific article published on 08 March 2012

Brachytherapy patient safety events in an academic radiation medicine program.

scientific article

Canadian Partnership for Quality Radiotherapy (CPQR) and the Canadian Organization of Medical Physicists (COMP) - Driving safety and quality assurance practice in Canada through the development of technical quality control guidelines

scientific article

Changes in apparent diffusion coefficient and T2 relaxation during radiotherapy for prostate cancer.

scientific article published on 23 October 2012

Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx)

scientific article published on 29 August 2012

Chromosomal instability as a prognostic marker in cervical cancer

scientific article published on 6 May 2015

Clinical Application of High-Dose, Image-Guided Intensity-Modulated Radiotherapy in High-Risk Prostate Cancer

scientific article published on 03 September 2009

Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology

scientific article published on 01 May 2018

Comparing oxygen-sensitive MRI (BOLD R2*) with oxygen electrode measurements: a pilot study in men with prostate cancer.

scientific article published in September 2009

Comparison of dosimetric parameters derived from whole organ and wall contours for bladder and rectum in cervical cancer patients treated with intracavitary and interstitial brachytherapy.

scientific article published on 6 February 2018

Consolidative abdominopelvic radiotherapy after surgery and carboplatin/paclitaxel chemotherapy for epithelial ovarian cancer

scientific article

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy

article

Correction: Image guided dose escalated prostate radiotherapy: still room to improve

Correlations between dynamic contrast-enhanced magnetic resonance imaging–derived measures of tumor microvasculature and interstitial fluid pressure in patients with cervical cancer

article

Corrigendum to: “Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy” [Eur J Cancer 2012;48(9): 1318–25]

scholarly article published in European Journal of Cancer

Delineating the inner bladder surface using uniform contractions from the outer surface under variable bladder filling conditions

scientific article

Deriving mechanisms responsible for the lack of correlation between hypoxia and acidity in solid tumors

scientific article

Deriving patient-specific planning target volume for partial bladder image guided radiation therapy

scientific article

Developing a prognostic micro-RNA signature for human cervical carcinoma

scientific article published on 16 April 2015

Development of multiorgan finite element-based prostate deformation model enabling registration of endorectal coil magnetic resonance imaging for radiotherapy planning.

scientific article published in August 2007

Diffusion-weighted MRI in cervical cancer

scientific article published on 12 January 2008

Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study.

scientific article

Dosimetrically triggered adaptive intensity modulated radiation therapy for cervical cancer

scientific article published on 8 July 2014

Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Localization of Recurrent Prostate Cancer After External Beam Radiotherapy

scientific article published on 19 September 2007

Dynamics of tumor growth and combination of anti-angiogenic and cytotoxic therapies

scientific article published on 24 May 2007

Effects of the vascular disrupting agent ZD6126 on interstitial fluid pressure and cell survival in tumors

scientific article

Estimating hypoxic status in human tumors: a simulation using Eppendorf oxygen probe data in cervical cancer patients.

scientific article

Expanding global access to radiotherapy.

scientific article published on September 2015

Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation

scientific article published in July 2002

Fingerprint of cell metabolism in the experimentally observed interstitial pH and pO2 in solid tumors

scientific article published on 17 November 2009

Functional CT imaging of prostate cancer

scientific article published on 4 September 2003

Genomic biomarkers for precision radiation medicine

scientific article published on 01 May 2017

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells.

scientific article

Hedgehog inhibition enhances efficacy of radiation and cisplatin in orthotopic cervical cancer xenografts

scientific article published on 22 November 2016

Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation

scientific article published on 25 October 2011

Heterogeneity and power in clinical biomarker studies

scientific article published on 9 February 2009

High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone

article

High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer

scientific article published on July 2009

Hybrid adaptive radiotherapy with on-line MRI in cervix cancer IMRT.

scientific article

Hypoxia Marker GLUT-1 (Glucose Transporter 1) is an Independent Prognostic Factor for Survival in Bladder Cancer Patients Treated with Radical Cystectomy

scientific article published on 7 January 2016

Hypoxia and Predicting Radiation Response

scientific article published on 15 May 2015

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1

scientific article published on 12 March 2012

Hypoxia, Androgen Deprivation and Systemic Metastases in Prostate Cancer (In Response to “Antivascular Effects of Neoadjuvant Androgen Deprivation for Prostate Cancer: An In Vivo Human Study Using Susceptibility and Relaxitivity Dynamic MRI”: In

scientific article published on 01 March 2012

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

scientific article published on 17 September 2013

Image guided dose escalated prostate radiotherapy: still room to improve

scientific article published on 3 November 2009

Imaging biomarker dynamics in an intracranial murine glioma study of radiation and antiangiogenic therapy

scientific article published on 26 August 2012

Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy

scientific article published on 13 March 2007

Impact of tissue transport on PET hypoxia quantification in pancreatic tumours.

scientific article published on 22 December 2017

Improving patient outcomes and radiotherapy systems: A pan-Canadian approach to patient-reported outcome use

scientific article published on 24 August 2018

In Regard to Ishikawa et al.: Cyclooxygenase-2 Impairs Treatment Effect of Radiotherapy for Cervical Cancer by Inhibition of Radiation-Induced Apoptosis (Int J Radiat Oncol Biol Phys 2006;66:1347–1355)

scientific article published on 01 July 2007

In Reply to Smith and Eifel

scientific article published on 01 February 2014

Incident Learning Systems for Radiation Oncology: Development and Value at the Local, National and International Level.

scientific article

Inter- and Intrafractional Tumor and Organ Movement in Patients With Cervical Cancer Undergoing Radiotherapy: A Cinematic-MRI Point-of-Interest Study

article

Interfraction and intrafraction changes in amplitude of breathing motion in stereotactic liver radiotherapy.

scientific article published on 6 March 2010

Interindividual variability of arterial impulse response to intravenous injection of nonionic contrast agent (Iohexol) in DCE-CT study

scientific article published on October 2009

Intermediate dose–volume parameters and the development of late rectal toxicity after MRI-guided brachytherapy for locally advanced cervix cancer

article

Interobserver variation in postimplant computed tomography contouring affects quality assessment of prostate brachytherapy

scientific article published in January 2002

Interrelationship of proliferation and hypoxia in carcinoma of the cervix

scientific article published in January 2000

Interstitial fluid pressure in tumors: therapeutic barrier and biomarker of angiogenesis.

scientific article published on December 2008

Interstitial fluid pressure, vascularity and metastasis in ectopic, orthotopic and spontaneous tumours

scientific article

Interstitial permeability and elasticity in human cervix cancer

scientific article published on 03 December 2007

Invasive cervical cancer: a failure of screening

scientific article published on 7 December 2007

Inverse Relationship Between Biochemical Outcome and Acute Toxicity After Image-Guided Radiotherapy for Prostate Cancer

article

Is there a relationship between repopulation and hypoxia/reoxygenation? Results from human carcinoma of the cervix.

scientific article published on July 2003

Long-term outcome of radiation-based conservation therapy for invasive bladder cancer.

scientific article published on July 2007

Long-term performance of interstial fluid pressure and hypoxia as prognostic factors in cervix cancer

scientific article

MR-guided brachytherapy for cervical cancer: Quantifying process waste and identifying opportunities for system performance improvement

scientific article published on 11 November 2015

MR-guided prostate biopsy for planning of focal salvage after radiation therapy

scientific article

Magnetic Resonance Imaging-Guided Intracavitary Brachytherapy for Cancer of the Cervix

article

Managing a national radiation oncologist workforce: a workforce planning model

scientific article published on 31 January 2012

Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.

scientific article

Measurement of Tumor Hypoxia in Patients With Locally Advanced Cervical Cancer Using Positron Emission Tomography with 18F-Fluoroazomyin Arabinoside

scientific article published on 02 March 2018

Measurement of Tumor Hypoxia in Patients with Advanced Pancreatic Cancer Based on 18F-Fluoroazomyin Arabinoside Uptake

scientific article published on 14 January 2016

Medulloblastoma in adults.

scientific article

Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors

scientific article

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

scientific article published on 4 July 2013

Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies

scientific article published on 29 January 2012

Modified oxygen mask to induce target levels of hyperoxia and hypercarbia during radiotherapy: a more effective alternative to carbogen.

scientific article published in July 2007

Molecular targeted agents combined with chemo-radiation in the treatment of locally advanced cervix cancer.

scientific article published on May 2008

Moving toward uniform and evidence-based practice of radiotherapy for management of cervical cancer in Ontario, Canada

scientific article published on 19 April 2018

Multiphasic contrast injection for improved precision of parameter estimates in functional CT.

scientific article published on December 2008

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

scientific article

NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy

scientific article published on 2 November 2011

Neutrophil-lymphocyte ratio dynamics during concurrent chemo-radiotherapy for glioblastoma is an independent predictor for overall survival

scientific article published on 22 March 2017

Oncology Scan—The Role of Personalized Medicine in Gynecologic Cancers

scientific article published in August 2014

Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus

scientific article

PMH 9907: Long-term outcomes of a randomized phase 3 study of short-term bicalutamide hormone therapy and dose-escalated external-beam radiation therapy for localized prostate cancer

scientific article published on 24 May 2016

Pathological predictors for site of local recurrence after radiotherapy for prostate cancer.

scientific article published in March 2012

Patient-reported sexual adjustment after definitive chemoradiation and MR-guided brachytherapy for cervical cancer

scientific article published on 30 November 2018

Patient-specific PTV margins in radiotherapy for bladder cancer – A feasibility study using cone beam CT

scientific article published on 26 May 2011

Pelvic Radiotherapy for Cancer of the Cervix: Is What You Plan Actually What You Deliver?

scientific article published on 01 May 2009

Pelvic lymph node topography for radiotherapy treatment planning from ferumoxtran-10 contrast-enhanced magnetic resonance imaging

scientific article

Phase I dose escalation study of concurrent palliative radiation therapy with sorafenib in three anatomical cohorts (Thorax, Abdomen, Pelvis): The TAP study

scientific article

Phase II Trial of Hypofractionated Image-Guided Intensity-Modulated Radiotherapy for Localized Prostate Adenocarcinoma

article

Planned versus ‘delivered’ bladder dose reconstructed using solid and hollow organ models during prostate cancer IMRT

scientific article published on 09 April 2016

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response.

scientific article

Plerixafor Improves Primary Tumor Response and Reduces Metastases in Cervical Cancer Treated with Radio-Chemotherapy

scientific article published on 3 October 2016

Polarographic electrode study of tumor oxygenation in clinically localized prostate cancer.

scientific article published in March 2004

Postoperative radiotherapy improves local control and survival in patients with uterine leiomyosarcoma.

scientific article published on 24 May 2013

Prognostic Significance of Human Papilloma Virus and p16 Expression in Patients with Vulvar Squamous Cell Carcinoma who Received Radiotherapy.

scientific article published on 12 February 2018

Prognostic value of pretreatment circulating neutrophils, monocytes, and lymphocytes in oropharyngeal cancer stratified by human papillomavirus status

scientific article published on 21 October 2014

Proliferation measurements with flow cytometry Tpot in cancer of the uterine cervix: correlation between two laboratories and preliminary clinical results

scientific article published in July 1995

Propensity Score Analysis of Radical Cystectomy Versus Bladder-Sparing Trimodal Therapy in the Setting of a Multidisciplinary Bladder Cancer Clinic

scientific article published on 14 April 2017

Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma

scientific article

Quality in cancer care: Lessons from the Canadian partnership for quality radiotherapy.

scientific article published in January 2018

Quality standards in radiation medicine

scientific article published on 5 November 2013

Quantifying hypoxia in human cancers using static PET imaging

scientific article published on 25 October 2016

Quantitative Imaging in Radiation Oncology: An Emerging Science and Clinical Service.

scientific article published on 15 May 2015

Radiation and Heat Improve the Delivery and Efficacy of Nanotherapeutics by Modulating Intratumoral Fluid Dynamics

scientific article published on 20 July 2018

Radiation effects on the tumor microenvironment: Implications for nanomedicine delivery.

scientific article published on June 2016

Radiation therapy quality-of-care indicators for locally advanced cervical cancer: A consensus guideline

scientific article published on 28 January 2016

Radiosurgery scope of practice in Canada: a report of the Canadian association of radiation oncology (CARO) radiosurgery advisory committee

scientific article

Radiotherapy for atypical or malignant intracranial meningioma.

scientific article published on March 1996

Radiotherapy for bladder cancer

scientific article published on January 2007

Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma

scientific article published in July 1998

Recurrent intracranial epidermoid cyst treated with radiotherapy

scientific article published in 1995

Relations between non-protein sulfydryl levels in the nucleus and cytoplasm, tumor oxygenation, and clinical outcome of patients with uterine cervical carcinoma

scientific article published in January 2005

Repeatability and reproducibility of MRI-based radiomic features in cervical cancer

scientific article published on 19 March 2019

Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response

scientific article published on 18 October 2013

Role of Principal Component Analysis in Predicting Toxicity in Prostate Cancer Patients Treated With Hypofractionated Intensity-Modulated Radiation Therapy

article

Salvage radiotherapy following radical prostatectomy.

scientific article

Simultaneous nonrigid registration, segmentation, and tumor detection in MRI guided cervical cancer radiation therapy

scientific article published on 06 February 2012

Sorafenib Increases Tumor Hypoxia in Cervical Cancer Patients Treated With Radiation Therapy: Results of a Phase 1 Clinical Study.

scientific article published on 18 September 2015

Stage II testicular seminoma: patterns of recurrence and outcome of treatment.

scientific article published on June 2004

Strategic planning in an academic radiation medicine program.

scientific article published on 20 December 2017

Suppression of vascular endothelial growth factor receptor 3 (VEGFR3) and vascular endothelial growth factor C (VEGFC) inhibits hypoxia-induced lymph node metastases in cervix cancer.

scientific article

TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair

scientific article published on 5 August 2013

Targeting Tumoral Hypoxia: Finding Opportunity in Complexity

scientific article published on September 1, 2012

Targeting the CXCL12/CXCR4 Pathway and Myeloid Cells to Improve Radiation Treatment of Locally Advanced Cervical Cancer.

scientific article published on 8 February 2018

Technique adaptation, strategic replanning, and team learning during implementation of MR-guided brachytherapy for cervical cancer.

scientific article

Technological advances in radiotherapy for cervical cancer

scientific article published on September 2011

The Canadian National System for Incident Reporting in Radiation Treatment (NSIR-RT) Taxonomy

scientific article published on 30 January 2016

The Effect of Dose Grid Resolution on Dose Volume Histograms for Slender Organs at Risk during Pelvic Intensity-modulated Radiotherapy

article

The Effects of External Beam Radiotherapy on the Normal Urinary Bladder—A Histopathological Review

article

The Influence of Programmatic Change on Radiation Therapist Research Capacity—A Single-center Case Study

scientific article published on 10 December 2009

The Practice of Radiation Oncology in Canada

scientific article published on 14 December 2016

The Role of Elective Para-aortic Lymph Node Irradiation in Patients with Locally Advanced Cervical Cancer

scientific article published on 04 September 2014

The Utility of Serum CA9 for Prognostication in Prostate Cancer

scientific article published on September 2016

The clinical significance of hypoxia in human cancers

scientific article published in March 2015

The effect of delineation method and observer variability on bladder dose-volume histograms for prostate intensity modulated radiotherapy

scientific article published on 22 August 2011

The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure

scientific article published in July 2004

The inclusion of capillary distribution in the adiabatic tissue homogeneity model of blood flow

scientific article published in May 2001

The initiation of a multidisciplinary bladder cancer clinic and the uptake of neoadjuvant chemotherapy: A time-series analysis.

scientific article published on January 2016

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation

scientific article published on 10 June 2015

The relationship between external beam radiotherapy dose and chronic urinary dysfunction--a methodological critique

scientific article published on October 2010

The significance of tumoral ERCC1 status in patients with locally advanced cervical cancer treated with chemoradiation therapy: a multicenter clinicopathologic analysis

scientific article published on 24 July 2012

Time response of interstitial fluid pressure measurements in cervix cancer

scientific article published in July 2004

Trends in the utilization of brachytherapy in cervical cancer in the United States

scientific article published on 9 July 2013

Tumor Hypoxia Predicts Biochemical Failure following Radiotherapy for Clinically Localized Prostate Cancer

scientific article published on 31 March 2012

Tumor and normal tissue dosimetry changes during MR-guided pulsed-dose-rate (PDR) brachytherapy for cervical cancer

scientific article published on 27 March 2013

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer

scientific article published in February 2002

Tumor microenvironment determines response to a heat-activated thermosensitive liposome formulation of cisplatin in cervical carcinoma

scientific article published on 28 July 2017

Tumor size and oxygenation are independent predictors of nodal diseases in patients with cervix cancer

scientific article published in November 2001

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

scientific article

Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis

scientific article published in February 2004

Use of low-value radiotherapy practices in Canada: an analysis of provincial cancer registry data

scientific article

Use of palliative radiotherapy trials for clinical biomarker development

scientific article published on September 2008

Uterine papillary serous carcinoma: evaluation of multimodality treatment with abdominopelvic radiotherapy and chemotherapy.

scientific article

Validation of supervised automated algorithm for fast quantitative evaluation of organ motion on magnetic resonance imaging.

scientific article published on 22 January 2008

Vulnerabilities of radiomic signature development: The need for safeguards

article