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List of works by Brendan T. Griffin

A Dairy-Derived Ghrelinergic Hydrolysate Modulates Food Intake In Vivo

scholarly article by Ken Howick published in September 2018

A comparison of intestinal lymphatic transport and systemic bioavailability of saquinavir from three lipid-based formulations in the anaesthetised rat model

scientific article published in July 2006

A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene--in vivo evaluation using a pig model.

scientific article published on 21 June 2013

An examination of the effect of intestinal first pass extraction on intestinal lymphatic transport of saquinavir in the rat.

scientific article published on 2 November 2007

Application of a Physiologically-Based Pharmacokinetic Model for the Prediction of Bumetanide Plasma and Brain Concentrations in the Neonate

scientific article published on 10 January 2018

Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - a PEARRL review

scientific article published on 05 July 2018

Applying Computational Predictions of Biorelevant Solubility Ratio upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number

scientific article published on 31 October 2020

Assessing awareness and attitudes of healthcare professionals on the use of biosimilar medicines: A survey of physicians and pharmacists in Ireland

scientific article published on 27 June 2017

Behavioural characterization of ghrelin ligands, anamorelin and HM01: Appetite and reward-motivated effects in rodents

scientific article published on 14 February 2020

Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport

scientific article published on 01 March 2010

Biopharmaceutical challenges associated with drugs with low aqueous solubility--the potential impact of lipid-based formulations.

scientific article published on 6 November 2007

Biopharmaceutical modeling of drug supersaturation during lipid-based formulation digestion considering an absorption sink

scientific article published on 25 June 2014

Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression

scientific article published on 26 October 2015

Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate.

scientific article

Enhanced colonic delivery of ciclosporin A self-emulsifying drug delivery system encapsulated in coated minispheres

scientific article published on 17 June 2015

Exploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramide

scientific article published on 17 March 2018

Exploring the Impact of Drug Properties on the Extent of Intestinal Lymphatic Transport - In Vitro and In Vivo Studies

scientific article published on 27 November 2014

Expression of two Listeria monocytogenes antigens (P60 and LLO) in Lactococcus lactis and examination for use as live vaccine vectors

scientific article published on 20 May 2010

Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo

scientific article published on 4 July 2016

Food for thought: formulating away the food effect - a PEARRL review

scientific article published on 28 June 2018

From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

scientific article published on 27 January 2017

Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions

scientific article published on 01 April 2019

Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin

scientific article published on 26 April 2020

Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability

scientific article published on 9 August 2013

Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility.

scientific article

Impact of body composition parameters on clinical outcomes in patients with metastatic castrate-resistant prostate cancer treated with docetaxel

scientific article

Impact of host and environmental factors on β-glucuronidase enzymatic activity: implications for gastrointestinal serotonin

scientific article published on 09 March 2020

In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide

scientific article published on 7 December 2015

In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation.

scientific article published on 26 January 2017

Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings

scientific article published on January 2012

Knowledge of Adverse Drug Reaction Reporting and the Pharmacovigilance of Biological Medicines: A Survey of Healthcare Professionals in Ireland.

scientific article published in June 2018

Lactococcus lactis as a cell factory for delivery of therapeutic proteins.

scientific article published on February 2010

Lipid-based nanocarriers for oral peptide delivery.

scientific article published on 11 April 2016

Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments.

scientific article

Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches - a PEARRL review

scientific article published on 02 August 2018

Mesoporous silica-based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate

scientific article published on 20 June 2017

Microbiome-Mediated Bile Acid Modification: Role in Intestinal Drug Absorption and Metabolism.

scientific article published on 13 April 2018

New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib

scientific article published on 22 February 2019

Opportunities and Challenges for Oral Delivery of Hydrophobic Versus Hydrophilic Peptide and protein-like Drugs Using lipid-based Technologies ⬇️

scientific article published on December 1, 2011

P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents

scientific article

PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability.

scientific article published on 30 June 2014

Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs.

scientific article published on 16 June 2016

Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives

scientific article published on 4 March 2016

Regulation of biosimilar medicines and current perspectives on interchangeability and policy

scientific article published on 05 September 2018

Silicon microfluidic flow focusing devices for the production of size-controlled PLGA based drug loaded microparticles

scientific article published on 28 March 2014

Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax

scientific article published on 18 June 2020

Supersaturated lipid-based drug delivery systems - exploring impact of lipid composition type and drug properties on supersaturability and physical stability

scientific article published on 05 February 2020

Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization

scientific article published on 23 November 2017

The Impact of the Gut Microbiota on Drug Metabolism and Clinical Outcome

scientific article

The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram

scientific article published on 23 November 2013

The PEARRL reviews - innovative drug development strategies tailored to facilitate earlier access to new oral medicines

scientific article published on 01 April 2019

The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat.

scientific article published on 10 December 2014

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review.

scientific article published on 10 April 2018

Toward the establishment of a standardized pre-clinical porcine model to predict food effects - Case studies on fenofibrate and paracetamol

scientific article published on 28 May 2019

Towards simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients

scientific article published on 30 October 2020

Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics

scientific article

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