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List of works by Maria Svelto

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

scientific article published on 18 December 2013

A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria.

scientific article

A heterotrimeric G protein of the Gi family is required for cAMP-triggered trafficking of aquaporin 2 in kidney epithelial cells.

scientific article published on August 1998

A novel human aquaporin-4 splice variant exhibits a dominant-negative activity: a new mechanism to regulate water permeability.

scientific article published on 19 December 2013

A novel therapeutic effect of statins on nephrogenic diabetes insipidus

scientific article

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency

scientific article

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

scientific journal article

AQP4-dependent water transport plays a functional role in exercise-induced skeletal muscle adaptations

scientific article

AQP5 is expressed in type-B intercalated cells in the collecting duct system of the rat, mouse and human kidney.

scientific article published on 14 December 2011

Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling.

scientific article

Actin cytoskeleton remodeling governs aquaporin-4 localization in astrocytes.

scientific article

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

scientific article

Adult murine CNS stem cells express aquaporin channels

scientific article published on 01 February 2006

Altered Expression of Renal Aquaporins and -Adducin Polymorphisms May Contribute to the Establishment of Salt-Sensitive Hypertension

scientific article published in July 2011

Altered blood-brain barrier development in dystrophic MDX mice.

scientific article

Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis

scientific article published on 31 July 2008

Altered urinary excretion of aquaporin 2 in IgA nephropathy

scientific article published on 08 August 2011

Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading.

scientific article published on 24 August 2010

Aquaporin-1 expression in the chick embryo chorioallantoic membrane

scientific article published in October 2002

Aquaporin-2 Excretion and Renal Function during the 1st Week of Life in Preterm Newborn Infants

Aquaporin-2 urinary excretion in preterm infants: relationship to diuresis and vasopressin.

scientific article published on December 2010

Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4 isoform-dependent sensitivity and specificity

scientific article

Aquaporin-4 deficiency in skeletal muscle and brain of dystrophic mdx mice.

scientific article

Aquaporin-4 expression during development of the cerebellum.

scientific article

Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodies

scientific article

Aquaporin-4-containing astrocytes sustain a temperature- and mercury-insensitive swelling in vitro

scientific article published on 01 July 2000

Aquaporin-CHIP-related protein in frog urinary bladder: localization by confocal microscopy

scientific article published in February 1995

Aquaporins as Targets for Drug Discovery

scientific article published in August 2007

Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease.

scientific article published on January 2008

Automated cell-based assay for screening of aquaporin inhibitors.

scientific article published in October 2009

Biophysical assessment of aquaporin-9 as principal facilitative pathway in mouse liver import of glucogenetic glycerol

scientific article published on 23 March 2012

Bradykinin signaling counteracts cAMP-elicited aquaporin 2 translocation in renal cells

scientific article published on 10 August 2005

Calcium role in base-line and ADH-stimulated sodium transport in frog skin

scientific article published in January 1985

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

scientific article

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

scientific article published on 22 December 2011

Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis.

scientific article published on 6 June 2011

Clinical and functional characterization of a novel mutation in lamin a/c gene in a multigenerational family with arrhythmogenic cardiac laminopathy

scientific article (publication date: 2015)

Co-Regulated Pendrin and Aquaporin 5 Expression and Trafficking in Type-B Intercalated Cells under Potassium Depletion

scientific article published on 18 December 2013

Colchicine effect on the permeability of the whole epithelium and of isolated cells of frog skin

scientific article published on December 1, 1979

Colchicine inhibition of ADH effect on frog skin permeability

scientific article published in March 1978

Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice.

scientific article

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

scientific article

D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness.

scientific article published on 16 September 2011

DNA adducts, benzo(a)pyrene monooxygenase activity, and lysosomal membrane stability in Mytilus galloprovincialis from different areas in Taranto coastal waters (Italy).

scientific article

Different pattern of aquaporin-4 expression in extensor digitorum longus and soleus during early development

scientific article published in 2007

Double noradrenaline effect on nonelectrolyte permeability explained by α and β receptors stimulation in frog skin

scientific article published on January 1, 1979

Dystrophin-dependent and -independent AQP4 pools are expressed in the mouse brain.

scientific article published in June 2008

Effect of microgravity on gene expression in mouse brain.

scientific article published on 14 August 2008

Effect of roscovitine on intracellular calcium dynamics: differential enantioselective responses.

scientific article published on 29 October 2013

Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study

scientific article published on 9 October 2006

Evidence for a two-site model of forskolin action in frog urinary bladder

scientific article published in August 1987

Evidence for the role of calcium in the hydrosmotic response to antidiuretic hormone in frog skin

scientific article published in October 1984

Excessive signal transduction of gain-of-function variants of the calcium-sensing receptor (CaSR) are associated with increased ER to cytosol calcium gradient

scientific article

Expression and functional analysis of water channels in a stably AQP2-transfected human collecting duct cell line.

scientific article published on October 1996

Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium

scientific article published in June 2005

Expression of multiple AQP4 pools in the plasma membrane and their association with the dystrophin complex

scientific article

Extracellular GTP is a potent water-transport regulator via aquaporin 5 plasma-membrane insertion in M1-CCD epithelial cortical collecting duct cells

scientific article published on 7 March 2014

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells.

scientific article published on December 2004

Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

scientific article published on 20 August 2011

Functional down-regulation of volume-regulated anion channels in AQP4 knockdown cultured rat cortical astrocytes

scientific article published on 25 October 2006

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.

scientific article published on 4 April 2008

Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells

scientific article published in September 2002

Functional involvement of β3-adrenergic receptors in melanoma growth and vascularization.

scientific article published on 2 August 2013

Functional reconstitution of a rice aquaporin water channel, PIP1;1, by a micro-batchwise methodology.

scientific article

Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function.

scientific article published on 13 October 2005

Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle

scientific article published on 23 July 2008

High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells.

scientific article

Higher order structure of aquaporin-4

scientific journal article

Histamine treatment induces rearrangements of orthogonal arrays of particles (OAPs) in human AQP4-expressing gastric cells.

scientific article

Hypotonicity Induces Aquaporin-2 Internalization and Cytosol-to-Membrane Translocation of ICln in Renal Cells

scientific article published on 30 November 2006

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

scientific article published on 01 April 2007

Identification of a point mutation impairing the binding between aquaporin-4 and neuromyelitis optica autoantibodies

scientific article published on 19 September 2014

Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking

scientific article published on 26 July 2012

In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: a new drug target for hypertension?

scientific article published in January 2012

Inhibition of aquaporin-1 dependent angiogenesis impairs tumour growth in a mouse model of melanoma

scientific article published on 30 November 2012

Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.

scientific article published on 17 June 2011

Liver glycerol permeability and aquaporin-9 are dysregulated in a murine model of Non-Alcoholic Fatty Liver Disease

scientific article

MAL/VIP17, a new player in the regulation of NKCC2 in the kidney

scientific article

Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma

scientific article published in May 2001

Minireview: aquaporin 2 trafficking.

scientific article

NKCC2 activity is inhibited by the Bartter's syndrome type 5 gain-of-function CaR-A843E mutant in renal cells.

scientific article

NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension.

scientific article

Na+/K+-ATPase β1-subunit is recruited in Na-K-2Cl co-transporter isoform 2 multiprotein complexes in rat kidneys: possible role in blood pressure regulation

scientific article published in September 2014

Noradrenaline induced secretion of nonelectrolytes through frog skin

scientific article published in December 1977

Ontogeny, distribution, and possible functional implications of an unusual aquaporin, AQP8, in mouse liver

scientific article

Permeability Properties of Epithelia as Compared to Lipid Bdlayer Membranes

scientific article published in January 1973

Permeability Properties of the Frog Skin at Various Degrees of Edge Damage

scientific article published on December 1, 1975

Phloretin sensitive active urea absorption in frog skin

scientific article published in September 1982

Phorbol ester effect on the hydrosmotic response to vasopressin in frog skin

scientific article published in March 1987

Possible involvement of aquaporin-7 and -8 in rat testis development and spermatogenesis

scientific journal article

Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat

scientific article published on 11 October 2011

Preparative scale production and functional reconstitution of a human aquaglyceroporin (AQP3) using a cell free expression system.

scientific article published on 26 March 2013

Protective effect of hydrocortisone on vasopressin response in frog skin.

scientific article published on December 1981

Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile

scientific article published on 01 March 2005

Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease.

scientific article published on 13 December 2013

Role of nuclear Lamin A/C in cardiomyocyte functions

scientific article

Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts

scientific journal article

Rosiglitazone promotes AQP2 plasma membrane expression in renal cells via a Ca-dependent/cAMP-independent mechanism.

scientific article

Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis.

scientific article published in October 2004

Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells.

scientific article published in August 2003

Serum and CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis optica

scientific article published on 27 May 2011

The Authors Reply:

scientific article published in April 2015

The Inner Mitochondrial Membrane Has Aquaporin-8 Water Channels and Is Highly Permeable to Water

scientific article published in Journal of Biological Chemistry

The KATP channel is a molecular sensor of atrophy in skeletal muscle.

scientific article published on 11 January 2010

The role of aquaporin-4 in the blood-brain barrier development and integrity: studies in animal and cell culture models.

scientific article

Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells.

scientific article

Translational regulation mechanisms of aquaporin‐4 supramolecular organization in astrocytes

scientific article published on August 17, 2011

Transport of some non-electrolytes through amphibian skins

scientific article published in October 1973

Triiodothyronine modulates the expression of aquaporin-8 in rat liver mitochondria.

scientific article published in January 2007

Water handling and aquaporins in bile formation: recent advances and research trends

scientific article published on November 2003

Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

scientific article published on 24 April 2006

Water permeability of rat liver mitochondria: A biophysical study

scientific article published on 21 July 2006

cAMP levels and α and β receptors stimulation by noradrenaline in frog skin

scientific article published in January 1983

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.

scientific article published in April 2003

siRNA-chitosan complexes in poly(lactic-co-glycolic acid) nanoparticles for the silencing of aquaporin-1 in cancer cells.

scientific article published on 21 June 2013

β3-adrenergic receptor activity modulates melanoma cell proliferation and survival through nitric oxide signaling

scientific article published on 6 March 2014