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List of works by Hartmut Derendorf

A Markov chain model to evaluate the effect of CYP3A5 and ABCB1 polymorphisms on adverse events associated with tacrolimus in pediatric renal transplantation.

scientific article published on 30 August 2013

A Tribute to Dr. Marcus E. Brewster: October 14, 1957-September 15, 2014.

scientific article published on 22 March 2016

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis.

scientific article published on 7 February 2018

A mathematical model-based analysis of the time-kill kinetics of ceftazidime/avibactam against Pseudomonas aeruginosa

scientific article published on 3 February 2018

A need to revisit clinical breakpoints of tigecycline: effect of atypical non-linear plasma protein binding

scientific article published on 22 February 2017

A novel breath test to directly measure use of vaginal gel and condoms

scientific article

A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids.

scientific article published in April 1999

A pharmacokinetic/pharmacodynamic mathematical model accurately describes the activity of voriconazole against Candida spp. in vitro

scientific article published on 22 January 2008

A selective LC/RIA for dexamethasone and its prodrug dexamethasone-21-isonicotinate in biological fluids

scientific article published in January 1991

A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma.

scientific article published in February 2000

AAPS-FDA Workshop White Paper: microdialysis principles, application, and regulatory perspectives

scientific article published on 01 May 2007

AAPS-FDA workshop white paper: Microdialysis principles, application, and regulatory perspectives report from the Joint AAPS-FDA Workshop, November 4–5, 2005, Nashville, TN

scientific article published on 23 February 2007

AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectives.

scientific article

Absolute and relative bioavailabilities of dodeca-2E, 4E, 8E, 10E/Z-tetraenoic acid isobutylamides after intravenous and oral single doses in rats.

scientific article

Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats

scientific article published on 20 May 2011

Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers

scientific article published in November 2006

Achieving eradication of MRSA colonization in patients. Therapeutic options

scientific article published in January 2006

Antimicrobial tissue concentrations

scientific article published on September 2003

Application of pharmacokinetic/pharmacodynamic modelling and simulation for the prediction of target attainment of ceftobiprole against meticillin-resistant Staphylococcus aureus using minimum inhibitory concentration and time-kill curve based appro

scientific article published in October 2013

Application of two-point assay of digoxin serum concentration in studying population pharmacokinetics in Egyptian pediatric patients with heart failure: does it make sense?

scientific article

Assessment of the Impact of Dosing Time on the Pharmacokinetics/Pharmacodynamics of Prednisolone

scientific article published in June 2008

Assessment of the impact of dosing time on the pharmacokinetics/pharmacodynamics of prednisolone

scientific article published on 25 June 2008

Bioanalytical method development and validation for determination of fibroblast growth factor peptide and its application to pharmacokinetic studies

scientific article published on 21 December 2018

Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray

scientific article

Bioavailability and metabolism of mometasone furoate: pharmacology versus methodology

scientific article

Bioavailability of dodeca-2, 4, 8, 10-tetraenoic acid isobutylamides after oral administration in rats and distribution in various tissues

scientific article published on 12 November 2009

Calculated initial parenteral treatment of bacterial infections: Pharmacokinetics and pharmacodynamics

scientific article published on 26 March 2020

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

scientific article published on 06 April 2020

Cavitary penetration of levofloxacin among patients with multidrug-resistant tuberculosis

scientific article published on 16 March 2015

Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections

scientific article

Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

scientific article published on 03 March 2009

Characterizing the effects of caspofungin on Candida albicans, Candida parapsilosis, and Candida glabrata isolates by simultaneous time-kill and postantifungal-effect experiments

scientific article published on July 2006

Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids.

scientific article published on 21 June 2016

Class-dependent relevance of tissue distribution in the interpretation of anti-infective pharmacokinetic/pharmacodynamic indices

scientific article published on May 2010

Clinical PK/PD modelling as a tool in drug development of corticosteroids

scientific article published on 01 October 1997

Clinical Pharmacokinetics and Pharmacodynamics of Ceftazidime-Avibactam Combination: A Model-Informed Strategy for its Clinical Development

scientific article published on 01 May 2019

Clinical microdialysis in skin and soft tissues: an update

scientific article

Clinical pharmacokinetics and pharmacodynamics of tigecycline

scientific article published on January 2009

Clinical pharmacokinetics of meropenem and biapenem in bile and dosing considerations for biliary tract infections based on site-specific pharmacodynamic target attainment

scientific article published on 26 September 2011

Clinical trials and dipyridamole formulation selection

scientific article (publication date: 2007)

Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids.

scientific article

Comparative target site pharmacokinetics of immediate- and modified-release formulations of cefaclor in humans

scientific article

Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin

scientific article

Concentration-response studies and modelling of the pharmacodynamics of linezolid: Staphylococcus aureus versus Enterococcus faecium

scientific article published on 22 October 2014

Core Entrustable Professional Activities in Clinical Pharmacology: Pearls for Clinical Practice: Drug-Drug and Food-Drug Interactions

scientific article published on 07 March 2018

Corticosteroid pharmacokinetic/pharmacodynamic parameters and their relationship to safety and efficacy

scientific article

Cortisol suppression as a surrogate marker for inhaled corticosteroid-induced growth retardation in children

scientific article

Dermal pharmacokinetics of Terpinen-4-ol following topical administration of Zingiber cassumunar (plai) oil

scientific article published in October 2012

Dermal pharmacokinetics of pyrazinamide determined by microdialysis sampling in rats

scientific article published on 12 October 2017

Determination of Dermal Pharmacokinetics by Microdialysis Sampling in Rats

scientific article published on 26 April 2019

Determination of atypical nonlinear plasma−protein-binding behavior of tigecycline using an in vitro microdialysis technique

scientific article published on 24 January 2014

Development and validation of a HPLC-MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study

scientific article published on 22 December 2014

Development and validation of a LC-MS quantification method for the lantibiotic MU1140 in rat plasma

scientific article published on 24 December 2008

Development and validation of a LC-MS/MS method based on a new 96-well Hybrid-SPE™-precipitation technique for quantification of CYP450 substrates/metabolites in rat plasma

article

Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model

scientific article published on 03 August 2018

Development of clinical pharmacy services in Australia, Austria, Belgium, Bosnia-Herzegovina, Canada, Germany, Japan, Kosovo, Switzerland, the Netherlands, Thailand, USA and correlation with educational standards, level of research, and implemen

scientific article published on 01 November 2018

Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms

scientific article published in October 2004

Dipyridamole bioavailability in subjects with reduced gastric acidity

scientific article (publication date: July 2005)

Does the Anesthetic Urethane Influence the Pharmacokinetics of Antifungal Drugs? A Population Pharmacokinetic Investigation in Rats

scientific article published on 18 June 2015

Dose Optimization of Moxifloxacin and Linezolid Against Tuberculosis Using Mathematical Modeling and Simulation

scientific article published on 29 October 2018

Drug-Drug Interactions: Progress Over the Past Decade and Looking Ahead to the Future

scientific article published on 12 April 2019

Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts

scientific article published on 19 May 2017

Duffy antigen modifies the chemokine response in human endotoxemia

scientific article published in January 2008

Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats.

scientific article published on 22 May 2008

Effect of high doses of glucocorticoids on the kinetics of human white blood cells in vivo

scientific article published on 01 March 1988

Effect of protein binding on the pharmacological activity of highly bound antibiotics

scientific article published on 8 September 2008

Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model

scientific article published on 19 January 2015

Effect of simulated microgravity on the disposition and tissue penetration of ciprofloxacin in healthy volunteers

scientific article published in July 2005

Effects of fentanyl dose and exposure duration on the affective and somatic signs of fentanyl withdrawal in rats

scientific article published on 27 June 2008

Electroencephalogram effects of armodafinil: comparison with behavioral alertness

scientific article published on August 2013

Electroencephalogram-based pharmacodynamic measures: a review.

scientific article published on March 2012

Enhanced in vitro tigecycline activity in the presence of chelating agents

scientific article

Enhanced penetration of moxifloxacin into rat prostate tissue evidenced by microdialysis

scientific article published on 29 July 2014

Enzyme- and transporter-mediated beverage-drug interactions: An update on fruit juices and green tea.

scientific article published on 10 June 2015

Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: pharmacokinetics with special consideration of free-drug concentration.

scientific article published on 21 December 2006

Ertapenem: the new carbapenem 5 years after first FDA licensing for clinical practice

scientific article published on February 2007

Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily

scientific article published on 02 December 2013

Evaluation of in vitro synergy between vertilmicin and ceftazidime against Pseudomonas aeruginosa using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

scientific article published on November 2014

Evaluation of pulmonary absorption using pharmacokinetic methods

scientific article

Evaluation of the effects of Maytenus ilicifolia on the activities of cytochrome P450 3A and P-glycoprotein

scientific article published on 12 May 2020

Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century

scientific article published on September 2000

Excessive lysosomal ion-trapping of hydroxychloroquine and azithromycin

scientific article published on 07 May 2020

Feasibility of a breath test for monitoring adherence to vaginal administration of antiretroviral microbicide gels

scientific article published on 24 January 2013

Gastric-acid-mediated drug-drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies

scientific article published on 12 January 2019

Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model

scientific article published on 24 December 2015

Grapefruit Juice–Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells

scientific article published on 01 October 2007

Grapefruit-medication interactions

scientific article

HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats

scientific article published on 5 March 2011

Herb-drug interactions

How important are gender differences in pharmacokinetics?

scientific article

How the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroids.

scientific article

Human serum binding and its effect on the pharmacodynamics of the lantibiotic MU1140 ⬇️

scientific article published on September 30, 2010

Hyperforin in St. John's wort drug interactions

scientific article

Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults

scientific article published on 01 July 2019

In memoriam: William A. Craig.

scientific article published on 20 April 2015

In vitro microdialysis sampling of docetaxel

scientific article published in November 2004

In vitro pharmacodynamic models to determine the effect of antibacterial drugs

scientific article published on 21 December 2009

In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms

scientific article published on 21 April 2016

Influence of CYP3A5 6986A > G and ABCB1 3435C > T Polymorphisms on Adverse Events Associated With Tacrolimus in Jordanian Pediatric Renal Transplant Patients.

scientific article

Inhaled corticosteroids: past lessons and future issues

scientific article published on September 2003

Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents - minimum inhibitory concentration versus time-kill curves

scientific article published on 01 June 2007

Interstitial tissue concentrations of cefpodoxime

scientific article

Intranasal loteprednol etabonate in healthy male subjects: pharmacokinetics and effects on endogenous cortisol

scientific article published in May 2004

Isolation and HPLC quantitative analysis of antioxidant flavonoids from Alternanthera tenella Colla

scientific article published on 01 January 2006

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue

scientific article published on May 2004

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC

scientific article published on February 2004

Largazole pharmacokinetics in rats by LC-MS/MS.

scientific article published on 20 March 2014

Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis

scientific article published on 3 April 2017

Measurement of voriconazole activity against Candida albicans, C. glabrata, and C. parapsilosis isolates using time-kill methods validated by high-performance liquid chromatography

scientific article published on 21 May 2007

Measuring drug distribution in the critically ill patient.

scientific article published on 03 September 2014

Mechanism-based PK/PD model for the lymphocytopenia induced by endogenous and exogenous corticosteroids

scientific article published on 01 August 1999

Medications in Space: In Search of a Pharmacologist's Guide to the Galaxy

scientific article published on 14 August 2019

Microdialysis as a tool in local pharmacodynamics

scientific article published on 7 April 2006

Microdialysis for in vivo pharmacokinetic/pharmacodynamic characterization of anti-infective drugs

scientific article

Microdialysis of Large Molecules

scientific article published on 23 September 2016

Microdialysis of triamcinolone acetonide in rat muscle

scientific article published in February 2003

Microdialysis sampling to monitor target-site vancomycin concentrations in septic infants: a feasible way to close the knowledge gap

Model-based drug approval - the rubber hits the road

scientific article published on 01 September 2012

Moxifloxacin distribution in the interstitial space of infected decubitus ulcer tissue of patients with spinal cord injury measured by in vivo microdialysis

scientific article published on 01 January 2006

Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study

scientific article published on 23 November 2017

Mycobacterium tuberculosis Strains H37ra and H37rv have equivalent minimum inhibitory concentrations to most antituberculosis drugs

scientific article published on 01 April 2018

New antibiotics for treatment of MRSA infections. Comparison of treatment with vancomycin

scientific article published in February 2006

Nonlinear Protein Binding: Not What You Think.

scientific article published on 4 April 2018

Novel formulations of cetrorelix acetate in healthy men: pharmacodynamic effects and noncompartmental pharmacokinetics

scientific article

Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development?

scientific article published on 02 August 2006

One Giant Leap for Pharmacology

scientific article published on 02 March 2020

Optimized therapeutic ratio of inhaled corticosteroids using retrometabolism.

scientific article published in March 2000

Oral adherence monitoring using a breath test to supplement highly active antiretroviral therapy.

scientific article published on January 2013

PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis ⬇️

scientific article published on October 11, 2010

PK-PD modelling of the effect of cefaclor on four different bacterial strains

scientific article

PK/PD: new insights for antibacterial and antiviral applications

scientific article published on 30 July 2008

Pediatric Dosing and Body Size in Biotherapeutics

scientific article published on 16 December 2010

Penetration of ertapenem into different pulmonary compartments of patients undergoing lung surgery

scientific article published in June 2005

Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis

scientific article published on 12 July 2006

Pharmacodynamic activity of the lantibiotic MU1140.

scientific article published on 2 October 2008

Pharmacokinetic Properties of Pure Xanthones in Comparison to a Mangosteen Fruit Extract in Rats

Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats

scientific article published on 06 December 2019

Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration.

scientific article published in February 1998

Pharmacokinetic and pharmacodynamic evaluation of the lantibiotic MU1140.

scientific article published in May 2010

Pharmacokinetic and pharmacodynamic implications in inhalable antimicrobial therapy

scientific article published on 11 March 2015

Pharmacokinetic and pharmacodynamic properties of inhaled ciclesonide

scientific article published on 5 April 2007

Pharmacokinetic evaluation of avicularin using a model-based development approach

scientific article published on 17 March 2015

Pharmacokinetic herb-drug interactions: are preventive screenings necessary and appropriate?

scientific article

Pharmacokinetic interaction between endogenous cortisol and exogenous corticosteroids.

scientific article published in September 1995

Pharmacokinetic-pharmacodynamic modeling of the in vitro activities of oxazolidinone antimicrobial agents against methicillin-resistant Staphylococcus aureus

scientific article published on 28 September 2009

Pharmacokinetic-pharmacodynamic modelling of antibacterial activity of cefpodoxime and cefixime in in vitro kinetic models

scientific article published in February 2005

Pharmacokinetic/pharmacodynamic evaluation of anti-infective agents

scientific article

Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains

scientific article published on 27 December 2006

Pharmacokinetic/pharmacodynamic modeling of luteinizing hormone (LH) suppression and LH surge delay by cetrorelix after single and multiple doses in healthy premenopausal women

scientific article published in March 2003

Pharmacokinetic/pharmacodynamic modeling of total lymphocytes and selected subtypes after oral budesonide.

scientific article published on 22 April 2006

Pharmacokinetic/pharmacodynamic modelling and in vitro simulation of dynamic voriconazole-Candida interactions

scientific article

Pharmacokinetic/pharmacodynamic profile of posaconazole

scientific article published on June 2010

Pharmacokinetic/pharmacodynamic profile of voriconazole

scientific article published on January 2006

Pharmacokinetic/pharmacodynamic studies in drug product development

scientific article

Pharmacokinetics and Pharmacodynamics of Biotech Drugs

Pharmacokinetics and Pharmacodynamics of Biotech Drugs

Pharmacokinetics and bioavailability of herbal medicinal products.

scientific article

Pharmacokinetics and dose linearity testing of methylprednisolone phosphate

scientific article published in September 1989

Pharmacokinetics and pharmacodynamics in antibiotic dose optimization.

scientific article

Pharmacokinetics and pharmacodynamics of cloprednol

scientific article published on 01 January 1996

Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: a comparison with dexamethasone phosphate (DP).

scientific article published in April 2001

Pharmacokinetics and pharmacodynamics of glucocorticoid suspensions after intra-articular administration

scientific article published in March 1986

Pharmacokinetics and pharmacodynamics of inhaled corticosteroids

scientific article published on April 1998

Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the first-in-human study

scientific article published on December 2013

Pharmacokinetics and pharmacodynamics of prednisolone following extremely high dosage as prednisolone hemisuccinate

scientific article published on February 1987

Pharmacokinetics and rectal bioavailability of hydrocortisone acetate after single and multiple administration in healthy subjects and patients

scientific article published in May 2001

Pharmacokinetics and tissue distribution of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats.

scientific article published on 27 April 2009

Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers

scientific article published on 12 August 2008

Pharmacokinetics of modified-release prednisone tablets in healthy subjects and patients with rheumatoid arthritis

scientific article published on 24 January 2013

Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis

scientific article

Pharmacokinetics of piperacillin-tazobactam: intermittent dosing versus continuous infusion

scientific article published on January 2005

Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations

scientific article published on 12 March 2012

Pharmacometrics as a discipline is entering the "industrialization" phase: standards, automation, knowledge sharing, and training are critical for future success.

scientific article

Pharmacometrics in dose finding or dose optimization of anti-retroviral and anti-tubercular drugs

scientific article published on April 2011

Physiological, pharmacokinetic, and pharmacodynamic changes in space

scientific article published in August 2004

Polymethoxylated Flavones and Other Phenolic Derivates from Citrus in Their Inhibitory Effects on P-Glycoprotein-Mediated Transport of Talinolol in Caco-2 Cells

article

Population Pharmacokinetic Model of Human Insulin Following Different Routes of Administration ⬇️

scientific article published on October 12, 2010

Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children

scientific article

Population pharmacodynamic model of bronchodilator response to inhaled albuterol in children and adults with asthma

scientific article published on 26 June 2008

Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis.

scientific article published on 11 November 2013

Population pharmacokinetics and pharmacodynamics of inhaled ciclesonide and fluticasone propionate in patients with persistent asthma

scientific article published on 11 February 2010

Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed-effects analysis

scientific article published on 26 June 2014

Population pharmacokinetics of digoxin in Egyptian pediatric patients: impact of one data point utilization

scientific article published in November 2002

Population pharmacokinetics of eniporide and its metabolite in healthy subjects and patients with acute myocardial infarction

scientific article published in June 2005

Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury

scientific article published in September 2004

Potential of pharmacokinetic profiling for detecting herbal interactions with drugs

scientific article published on January 2008

Potentiation of ceftazidime by avibactam against β-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model

scientific article published on 10 January 2017

Preadolescent tobacco smoke exposure leads to acute nicotine dependence but does not affect the rewarding effects of nicotine or nicotine withdrawal in adulthood in rats

scientific article published on 6 March 2010

Predicting pediatric age-matched weight and body mass index

scientific article

Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming, and Humorous Pharmaceutical Scientist.

scientific article

Proposal for a standardised identification of the mono-exponential terminal phase for orally administered drugs.

scientific article published in April 2008

Protein binding of rifapentine and its 25-desacetyl metabolite in patients with pulmonary tuberculosis

scientific article

Protein binding: do we ever learn?

scientific article published on 02 May 2011

Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment.

scientific article

Quantitative Estimation of Plasma Free Drug Fraction in Patients With Varying Degrees of Hepatic Impairment: A Methodological Evaluation.

scientific article published on 5 March 2018

Quantitative determination of armodafinil in human plasma by liquid chromatography-electrospray mass spectrometry: Application to a clinical study

scientific article published on 07 August 2018

Race-Specific Pharmacodynamic Model of Propofol-Induced Loss of Consciousness

scientific article

Rational dosing of antibiotics: the use of plasma concentrations versus tissue concentrations

scientific article

Relationship between saliva levels of metamizol metabolites, bioavailability and analgesic efficacy

scientific article published on 01 January 1983

Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage Adjustments

scientific article

Repeated pre-exposure to tobacco smoke potentiates subsequent locomotor responses to nicotine and tobacco smoke but not amphetamine in adult rats

scientific article published on 17 August 2011

Resistance and the management of complicated skin and skin structure infections: the role of ceftobiprole ⬇️

scientific article published on October 5, 2010

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in Mice

scientific article published on 30 April 2018

Risk-benefit value of inhaled corticosteroids: a pharmacokinetic/pharmacodynamic perspective

scientific article

Risk-benefit value of inhaled glucocorticoids: a pharmacokinetic/pharmacodynamic perspective

scientific article published on January 2004

Roger W. Jelliffe, M.D. (1929-2020)

scientific article published on 13 August 2020

Role of Divalent Metal Ions in Atypical Nonlinear Plasma Protein Binding Behavior of Tigecycline

scientific article published on 8 September 2016

Role of drug absorption in the pharmacokinetics of therapeutic interventions for stroke ⬇️

scientific article published on October 1, 2010

Role of microdialysis in pharmacokinetics and pharmacodynamics: current status and future directions

scientific article published on March 2014

Role of pharmacokinetics in establishing bioequivalence for orally inhaled drug products: workshop summary report.

scientific article published on 31 March 2011

Science and Evidence-based Review and Approval of COVID-19 Vaccines: A Statement of Support for the U.S. FDA

scientific article published on 04 December 2020

Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily

scientific article

Sex related differences on valproic acid pharmacokinetics after oral single dose

scientific article published on 20 June 2013

Significance of protein binding in pharmacokinetics and pharmacodynamics

scientific article published on March 2010

Simulation-based sodium thiosulfate dosing strategies for the treatment of calciphylaxis

scientific article

Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model

scientific article published on 28 July 2015

Simultaneous HPLC analysis of triamcinolone acetonide and budesonide in microdialysate and rat plasma: Application to a pharmacokinetic study ⬇️

scientific article published on September 9, 2010

Simultaneous Retrodialysis by Calibrator for Rapid In Vivo Recovery Determination in Target Site Microdialysis

scientific article published on 30 April 2018

Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant

scientific article published on 19 July 2018

Single- and multiple-dose pharmacokinetics of oral creatine.

scientific article published on January 2003

Single-dose and steady-state pharmacokinetic and pharmacodynamic evaluation of therapeutically clinically equivalent doses of inhaled fluticasone propionate and budesonide, given as Diskus or Turbohaler dry-powder inhalers to healthy subjects

scientific article published in December 2001

Skin and soft tissue concentrations of tedizolid (formerly torezolid), a novel oxazolidinone, following a single oral dose in healthy volunteers

scientific article

Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery.

scientific article published on 2 May 2009

Soft-tissue penetration of ceftobiprole in healthy volunteers determined by in vivo microdialysis

scientific article published on 13 April 2009

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs

scientific article published on 01 April 2002

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

scientific article

Suppression of ciprofloxacin-induced resistant Pseudomonas aeruginosa in a dynamic kill curve system

scientific article published on 14 April 2011

Systemic availability and pharmacokinetics of thymol in humans.

scientific article published in July 2002

The Candida albicans phosphatase Inp51p interacts with the EH domain protein Irs4p, regulates phosphatidylinositol-4,5-bisphosphate levels and influences hyphal formation, the cell integrity pathway and virulence.

scientific article published in November 2008

The concentration-dependent binding of linagliptin (BI 1356) and its implication on efficacy and safety

scientific article published on 01 May 2012

The effect of critical illness on drug distribution

scientific article published on December 2011

The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide

scientific article published on August 2006

Theory and Application of Microdialysis in Pharmacokinetic Studies

scientific article published on 12 August 2015

Thromboelastographic and pharmacokinetic profiles of micro- and macro-emulsions of propofol in swine

scientific article

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

scientific article published on 13 April 2017

Tissue concentrations: do we ever learn?

scientific article published on 06 December 2007

Tissue penetration of cefpodoxime and cefixime in healthy subjects

scientific article published in May 2005

Tissue penetration of cefpodoxime into the skeletal muscle and lung in rats

scientific article published in July 2005

Tobacco smoke exposure enhances reward sensitivity in male and female rats

scientific article published on 07 January 2021

Tobacco smoke exposure induces nicotine dependence in rats

scientific article published on 21 November 2009

Toxicological and Pharmacokinetic Evaluation of Concomitant Intake of Grapefruit Juice and Simvastatin in Rats after Repeated Treatment over 28 Days

scientific article

Underdosing of ertapenem in critically ill patients with pneumonia confirmed by Monte Carlo simulations

scientific article published on 6 November 2009

Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization

scientific article published on 9 December 2016

Variability in response to cardiovascular drugs

scientific article published on January 2006

Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.

scientific article published in January 2006

What is the best marker for inhaled corticosteroid safety?

scientific article

When is protein binding important?

scientific article

[Problems of equivalency points during therapy with glucocorticoids. A comparison of the clinical pharmacokinetics and pharmacodynamics of prednisolone and methylprednisolone]

scientific article published on 01 December 1994

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