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List of works by Thomas J. Rosol

3-Phosphoinositide-dependent protein kinase-1/Akt signalling and inhibition in a canine prostate carcinoma cell line.

scientific article published on March 2007

A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone.

scientific article published on October 2005

A comparison of bone turnover in athymic (nude) and euthymic mice: Biochemical, histomorphometric, bone ash andin vitro studies

scientific article published on 01 January 1989

A human GRPr-transfected Ace-1 canine prostate cancer model in mice

scientific article published on 04 March 2016

A novel bioluminescent mouse model and effective therapy for adult T-cell leukemia/lymphoma

scientific article

A novel canine model for prostate cancer.

scientific article published on 17 January 2013

A review of the existing grading schemes and a proposal for a modified grading scheme for prostatic lesions in TRAMP mice

scientific article

AU-rich elements in the 3'-UTR regulate the stability of the 141 amino acid isoform of parathyroid hormone-related protein mRNA

scientific article published on 31 August 2012

Adrenal gland: structure, function, and mechanisms of toxicity.

scientific article

Alterations in serum parathyroid hormone and electrolyte concentrations and urinary excretion of electrolytes in horses with induced endotoxemia

scientific article published in March 2005

Alternative splicing of parathyroid hormone-related protein mRNA: expression and stability.

scientific article

Animal Models of Bone Metastasis.

scientific article

Animal Models of Cancer-Associated Hypercalcemia

scientific article published on 13 April 2017

Animal models of bone metastasis

article

Animal models of head and neck squamous cell carcinoma.

scientific article published on 24 November 2015

Anticancer properties of Monascus metabolites.

scientific article published on August 2014

Assessing Prostate Volume by Magnetic Resonance Imaging

scientific article published on 01 April 2005

Benign prostate hyperplasia: evaluation of treatment response with DCE MRI.

scientific article

Biodegradable nanoparticles for targeted ultrasound imaging of breast cancer cells in vitro.

scientific article published on 24 July 2007

Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.

scientific article published on April 2004

CD147 and Cyclooxygenase Expression in Feline Oral Squamous Cell Carcinoma

scientific article published on 13 August 2018

Canine prostate cancer cell line (Probasco) produces osteoblastic metastases in vivo

scientific article

Canine prostate carcinomas express markers of urothelial and prostatic differentiation.

scientific article published in March 2004

Canine prostate induces new bone formation in mouse calvaria: A model of osteoinduction by prostate tissue.

scientific article published in February 2002

Canine prostatic cancer cell line (LuMa) with osteoblastic bone metastasis

scientific article published on 29 April 2020

Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma

scientific article published on 14 August 2015

Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.

scientific article

Chronic Toxicity and Carcinogenicity Studies of the Long-Acting GLP-1 Receptor Agonist Dulaglutide in Rodents.

scientific article published on 10 April 2015

Cloning and sequence analysis of the complementary DNA for feline preproparathyroid hormone.

scholarly article

Cloning and sequencing of the 3'-region of the canine parathyroid hormone-related protein gene and analysis of alternate mRNA splicing in two canine carcinomas.

scientific article

Cloning of bovine parathyroid hormone-related protein (PTHrP) cDNA and expression of PTHrP mRNA in the bovine mammary gland

scientific article published on April 1, 1998

Cloning, comparative sequence analysis and mRNA expression of calcium-transporting genes in horses.

scientific article published on 11 March 2010

Combined zoledronic acid and meloxicam reduced bone loss and tumour growth in an orthotopic mouse model of bone-invasive oral squamous cell carcinoma.

scientific article published on 08 May 2013

Comparison of serum parathyroid hormone and ionized calcium and magnesium concentrations and fractional urinary clearance of calcium and phosphorus in healthy horses and horses with enterocolitis.

scientific article published in June 2001

Corrigendum to the inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach [Nucl Med Biol 43 (2016) 215-225].

scientific article published in December 2016

Detection of Interleukin-1 and Interleukin-6 on Cryopreserved Bovine Mammary Epithelial Cells in Vitro

scientific article published on 01 July 1997

Detection of Parathyroid Hormone—Related Protein in Cats with Humoral Hypercalcemia of Malignancy

scientific article published on 01 January 2002

Developing and fostering a dynamic program for training in veterinary pathology and clinical pathology: veterinary students to post-graduate education

scientific article (publication date: 2007)

Development of a brain metastatic canine prostate cancer cell line.

scientific article

Development of an orthotopic canine prostate cancer model expressing human GRPr

scientific article published on 11 July 2018

Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases

scientific article

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

article

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth

scientific article published on 26 October 2018

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.

scientific article published on 30 January 2017

Drugs which inhibit osteoclast function suppress tumor growth through calcium reduction in bone.

scientific article

E2f8 mediates tumor suppression in postnatal liver development

scientific article published on 25 July 2016

Effect of Transforming Growth Factor-β1 on Parathyroid Hormone-Related Protein Secretion and mRNA Expression by Normal Human Keratinocytes In Vitro

scientific article published on June 1, 1998

Effect of etidronate disodium on the development of bone lesions in an animal model of bone metastasis using the human prostate cancer cell line PC-3.

scientific article published on January 1991

Effect of serial intrauterine dimethyl sulfoxide infusions on the incidence of periglandular fibrosis in category II horse endometria

scientific article published on 01 January 1988

Effect of transforming growth factor alpha, parathyroid hormone-related protein, or their combination on bone histomorphometry

scientific article published on 01 November 1993

Effect of zoledronic acid and amputation on bone invasion and lung metastasis of canine osteosarcoma in nude mice.

scientific article

Effects of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and its analogues (EB1089 and analog V) on canine adenocarcinoma (CAC-8) in nude mice.

scientific article published in May 2002

Effects of Dulaglutide on Thyroid C Cells and Serum Calcitonin in Male Monkeys

scientific article published on 10 April 2015

Effects of Isoprothiolane on Cell Growth of Cultured Bovine Mammary Epithelial Cells

scientific article published on 01 May 1999

Effects of Lipopolysaccharide on Production of Interleukin-1 and Interleukin-6 by Bovine Mammary Epithelial Cells in vitro

article

Effects of chlorpromazine, pentoxifylline and dexamethasone on mRNA expression of lipopolysaccharide-induced inflammatory cytokines in bovine peripheral blood mononuclear cells.

scientific article published in August 2002

Effects of cyclosporin A on rat osteoblasts (ROS 17/2.8 cells) in vitro

scientific article published on October 1, 1992

Effects of hypercalcemia on serum concentrations of magnesium, potassium, and phosphate and urinary excretion of electrolytes in horses

scientific article published on 01 May 2007

Effects of parathyroid hormone-related protein and macrophage inflammatory protein-1α in Jurkat T-cells on tumor formationin vivoand expression of apoptosis regulatory genesin vitro

scientific article published on January 3, 2012

Effects of the GLP-1 Receptor Agonist Dulaglutide on the Structure of the Exocrine Pancreas of Cynomolgus Monkeys.

scientific article published on 9 June 2015

Effects of transforming growth factor-beta1 on parathyroid hormone-related protein mRNA expression and protein secretion in canine prostate epithelial, stromal, and carcinoma cells.

scientific article published in March 2004

Effects of transforming growth factor-α on parathyroid hormone- and parathyroid hormone-related protein- mediated bone resorption and adenylate cyclase stimulation in vitro

scientific article published on 01 October 1991

Engraftment and bone mass are enhanced by PTHrP 1-34 in ectopically transplanted vertebrae (vossicle model) and can be non-invasively monitored with bioluminescence and fluorescence imaging.

scientific article

Engraftment and tumorigenesis of HTLV-1 transformed T cell lines in SCID/bg and NOD/SCID mice

scientific article

Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation.

scientific article published on 28 March 2018

Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation

scientific article published on 27 December 2018

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

scientific article published on 20 October 2016

Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer

scientific article (publication date: 2013)

Evaluating the effects of mixed osteolytic/osteoblastic metastasis on vertebral bone quality in a new rat model

scientific article

Expression of PTHrP and the PTH/PTHrP Receptor in Purified Alveolar Epithelial Cells, Myoepithelial Cells, and Stromal Fibroblasts Derived from the Lactating Rat Mammary Gland

scientific article published on 01 May 1999

Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation

scientific article published on 9 June 2008

Extra-embryonic function of Rb is essential for embryonic development and viability

scientific article published in February 2003

FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients

scientific article published on 18 November 2019

Feline Mammary Cancer.

scientific article published on 8 June 2016

Feline head and neck squamous cell carcinoma: a natural model for the human disease and development of a mouse model.

scientific article published on June 2006

Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner.

scientific article

Gastrin-releasing peptide receptor (GRPr) promotes EMT, growth, and invasion in canine prostate cancer

scientific article published on 04 March 2016

Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.

scientific article published on 15 September 2016

Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation.

scientific article published on 31 July 2001

HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia

scientific article published on 03 October 2019

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

scientific article published on 27 August 2017

Head and Neck Squamous Cell Carcinoma: Measurement of Plasma Parathyroid Hormone-Related Protein and Serum and Urine Calcium Concentrations

scientific article published on 01 November 2000

Histone H1 phosphorylation in breast cancer

scientific article

Histopathologic and gross effects of testicular biopsy in the dog

scientific article published on 01 October 1989

Histotripsy focal ablation of implanted prostate tumor in an ACE-1 canine cancer model.

scientific article

Human Umbilical Cord Blood-Derived CD34+ Cells Reverse Osteoporosis in NOD/SCID Mice by Altering Osteoblastic and Osteoclastic Activities

scientific article published on June 18, 2012

Human parathyroid hormone-related protein in ovarian small cell carcinoma. An immunohistochemical study

article

Humoral hypercalcemia of malignancy: severe combined immunodeficient/beige mouse model of adult T-cell lymphoma independent of human T-cell lymphotropic virus type-1 tax expression.

scientific article published in June 2001

Hypercalcemia and high parathyroid hormone-related protein concentration associated with malignant melanoma in a dog.

scientific article published in July 2002

Incomplete but infectious vaccinia virions are produced in the absence of oncolysis in feline SCCF1 cells

scientific article published on 23 March 2015

Influence of Extracellular Matrix Macromolecules on Normal Human Keratinocyte Phenotype and Parathyroid Hormone-Related Protein Secretion and Expressionin Vitro

scientific article published on 01 January 1998

Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice.

scientific article published on 29 May 2007

Interferon-gamma targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases.

scientific article published on 05 December 2008

Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment.

scientific article published on 07 March 2013

Investigations on in vitro bone resorbing activity from athymic (nude) and euthymic mouse splenic leukocytes

scientific article published on 01 January 1989

Loss of myoferlin redirects breast cancer cell motility towards collective migration

scientific article (publication date: 2014)

Messenger RNA stability of parathyroid hormone-related protein regulated by transforming growth factor-beta1.

scientific article

Molecular cloning and expression of equine calcitonin, calcitonin gene-related peptide-I, and calcitonin gene-related peptide-II

article

Mouse development with a single E2F activator.

scientific article

Mouse model recapitulates the phenotypic heterogeneity of human adult T-cell leukemia/lymphoma in bone

scientific article published on 20 August 2019

NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcaemia of malignancy: cytokine gene expression profiling and in vivo bioluminescent imaging

scientific article

Nanoparticles as image enhancing agents for ultrasonography

scientific article published on 10 April 2006

Nanoparticulate paclitaxel demonstrates antitumor activity in PC3 and Ace-1 aggressive prostate cancer cell lines

scientific article published on 13 September 2013

New bone formation in nude mouse calvaria induced by canine prostate tissue

scientific article published in November 2002

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

scientific article

Nonproliferative and Proliferative Lesions of the Rat and Mouse Endocrine System

scientific article published on 28 July 2018

On-target effects of GLP-1 receptor agonists on thyroid C-cells in rats and mice.

scientific article published on February 2013

Osteolytic bone resorption in adult T-cell leukemia/lymphoma

scientific article

PTHrP 1-141 and 1-86 increase in vitro bone formation

scientific article

PTHrP gene expression in cancer: do all paths lead to Ets?

scientific article

Parathyroid Hormone-Related Protein Expression and Secretion in a Skin Organotypic Culture System

scientific article published on April 1, 1998

Parathyroid Hormone-Related Protein Production by Normal Human Keratinocytes in Vitro

article

Parathyroid hormone (PTH)-related protein, PTH, and 1,25-dihydroxyvitamin D in dogs with cancer-associated hypercalcemia

scientific article published on 01 September 1992

Parathyroid hormone-related protein binding to human T-cell lymphotropic virus type I-infected lymphocytes

scientific article published on January 1, 1992

Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors

scientific article published on 08 October 2019

Parathyroid hormone/parathyroid hormone-related protein receptor expression in nude mice with a transplantable canine apocrine adenocarcinoma (CAC-8) and humoral hypercalcaemia of malignancy

scientific article published on 01 April 1997

Pathogenesis of Bone Metastases: Role of Tumor-Related Proteins

scientific article published on 01 May 2000

Pathogenesis of humoral hypercalcemia of malignancy.

scientific article published on January 1988

Pathophysiology of calcium metabolism.

scientific article

Pharmacokinetic parameters as a potential predictor of response to pharmacotherapy in benign prostatic hyperplasia: a preclinical trial using dynamic contrast-enhanced MRI

scientific article published on 24 March 2006

Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species

scientific article published on 14 December 2016

Proceedings of the 2014 National Toxicology Program Satellite Symposium

scientific article

Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis

scientific article published on 23 April 2014

Proteoglycan 4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells

scientific journal article

Proto-Oncogene c-fosIs Transcriptionally Regulated by Parathyroid Hormone (PTH) and PTH-Related Protein in a Cyclic Adenosine Monophosphate-Dependent Manner in Osteoblastic Cells1

scientific article published on December 1, 1997

Quantitative bone histomorphometry in nude mice bearing a human squamous cell lung cancer

scientific article published on 01 June 1988

Quantitative evaluation of alternative promoter usage and 3' splice variants for parathyroid hormone-related protein by real-time reverse transcription-PCR.

scientific article

Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb -deficient mice

scientific article published on May 5, 2003

Recommendations from the INHAND Apoptosis/Necrosis Working Group

scientific article published on 14 February 2016

Reply to Dr Vogel

scientific article published on 01 November 2012

Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

scientific article published on 18 December 2011

Sequences of the cDNAs encoding canine parathyroid hormone-related protein and parathyroid hormone

scientific article published on July 28, 1995

Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer.

scientific article

Skeletal metastasis of prostate adenocarcinoma in rats: Morphometric analysis and role of parathyroid hormone-related protein

scientific article published on 01 May 1999

Spatial and temporal expression of parathyroid hormone-related protein during wound healing.

scientific article published on May 1999

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

scientific article published on September 2016

Stromal PTEN determines mammary epithelial response to radiotherapy

scientific article published in Nature Communications

Stromal and epithelial cells of the canine prostate express parathyroid hormone-related protein, but not the PTH/PTHrP receptor

scientific article published on July 1, 1998

Studies on chicken polyclonal anti-peptide antibodies specific for parathyroid hormone-related protein (1-36).

scientific article published on January 1993

TGF-β Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma.

scientific article published on 5 April 2015

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice

scientific article

The Effect of a Histone Deacetylase Inhibitor (AR-42) on Canine Prostate Cancer Growth and Metastasis

scientific article published on 9 February 2017

The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude mice.

scientific article

The inhibition of early stages of HER‐2/neu‐mediated mammary carcinogenesis by dietary n‐3 PUFAs

scientific article published on 05 December 2012

The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice.

scientific article

The role of Dickkopf-1 in bone development, homeostasis, and disease

scientific article published on 07 August 2008

The role of microRNA-148a and downstream DLGAP1 on the molecular regulation and tumor progression on human glioblastoma

scientific article published on 02 September 2019

Transcriptional regulation of parathyroid hormone-related protein promoter P2 by NF-kappaB in adult T-cell leukemia/lymphoma

scientific article published on 07 June 2007

Transforming growth factor-β1 regulates steady-state PTH/PTHrP receptor mRNA levels and PTHrP binding in ROS 17/2.8 osteosarcoma cells

scientific article published on 01 May 1994

Triple-negative breast cancer: is there a treatment on the horizon?

scientific article

Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions.

scientific article

Tumor microenvironment regulates metastasis and metastasis genes of mouse MMTV-PymT mammary cancer cells in vivo.

scientific article

Veterinarians in Biomedical Research: Building National Capacity

scientific article published on 01 January 2009

Veterinary Pathology Under the Microscope: Planning for the Future.

scientific article

Vitamin D Metabolites and Their Association with Calcium, Phosphorus, and PTH Concentrations, Severity of Illness, and Mortality in Hospitalized Equine Neonates

scientific article published on 5 June 2015

What Is Your Diagnosis? Extraskeletal mesenchymal chondrosarcoma.

scientific article

Zoledronic acid decreased osteolysis but not bone metastasis in a nude mouse model of canine prostate cancer with mixed bone lesions.

scientific article

Zoledronic acid reduces bone loss and tumor growth in an orthotopic xenograft model of osteolytic oral squamous cell carcinoma

scientific article

p16, pRb, and p53 in Feline Oral Squamous Cell Carcinoma

scientific article published on 18 August 2016