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List of works by Diana Spiegelberg

A novel CD44v6 targeting antibody fragment with improved tumor-to-blood ratio

scientific article published on February 2012

A real-time in vitro assay as a potential predictor of in vivo tumor imaging properties.

scientific article published on 21 September 2015

CD44v6-Targeted Imaging of Head and Neck Squamous Cell Carcinoma: Antibody-Based Approaches

scientific article published on 20 June 2017

Characterization of CD44 variant expression in head and neck squamous cell carcinomas

scientific article published on March 2014

Choice of labeling and cell line influences interactions between the Fab fragment AbD15179 and its target antigen CD44v6.

scientific article published on 29 October 2013

Determination of receptor protein binding site specificity and relative binding strength using a time-resolved competition assay.

scientific article published on 29 July 2014

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma.

scientific article

HSP90 inhibition in angiosarcoma

scientific article published in August 2017

Improved tumor-to-organ ratios of a novel 67Ga-human epidermal growth factor radionuclide conjugate with preadministered antiepidermal growth factor receptor affibody molecules.

scientific article

In vivo characterization of the novel CD44v6-targeting Fab fragment AbD15179 for molecular imaging of squamous cell carcinoma: a dual-isotope study.

scientific article published on 06 March 2014

Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy.

scientific article

The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach

scientific article published on 03 April 2020

The HSP90 inhibitor onalespib potentiates 177Lu‑DOTATATE therapy in neuroendocrine tumor cells

scientific article published on 30 September 2019

The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild-Type p53 Tumors

scientific article published on 19 July 2018

The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells

scientific article published on 19 September 2019

The effect of a dimeric Affibody molecule (ZEGFR:1907)2 targeting EGFR in combination with radiation in colon cancer cell lines.

scientific article

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

scientific article published on 6 October 2015

The radiosensitizer Onalespib increases complete remission in 177Lu-DOTATATE-treated mice bearing neuroendocrine tumor xenografts

scientific article published on 07 January 2020