List of works - Richard Weiss

A DNA vaccine encoding the outer surface protein C from Borrelia burgdorferi is able to induce protective immune responses

scientific article published on 01 September 2003

Allergen microarray detects high prevalence of asymptomatic IgE sensitizations to tropical pollen-derived carbohydrates

scientific article

Allergens are not pathogens: why immunization against allergy differs from vaccination against infectious diseases

scientific article

Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.

scientific article published on 28 June 2016

Arabidopsis MAP-Kinase 3 Phosphorylates UDP-Glucose Dehydrogenase: a Key Enzyme Providing UDP-Sugar for Cell Wall Biosynthesis

scientific article published on 08 December 2018

Behead and live long or the tale of cathepsin L.

scientific article

Bicistronic expression plasmid encoding allergen and anti-IgE single chain variable fragment antibody as a novel DNA vaccine for allergy therapy and prevention

scientific article published on 02 March 2006

C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria.

scientific article published on 14 February 2005

Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver.

scientific article published on 18 October 2011

Clinical significance of HLA-E*0103 homozygosity on survival after allogeneic hematopoietic stem-cell transplantation

scientific article published in August 2009

Confirmation of immuno-reactivity of the recombinant major birch pollen allergen Bet v 1a by affinity-CIEF.

scientific article published in July 2009

DNA and mRNA vaccination against allergies

scientific article published on 20 September 2018

DNA immunization in vivo down-regulates nuclear all-trans retinoic acid receptors in mouse spleen cells.

scientific article published on July 2000

Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development.

scientific article published on 26 February 2018

Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.

scientific article published on 13 November 2014

Differential effects of C3d on the immunogenicity of gene gun vaccines encoding Plasmodium falciparum and Plasmodium berghei MSP1(42).

scientific article published on 15 May 2010

Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin

scientific article published on 21 May 2020

Epidermal Langerhans Cells Are Dispensable for Humoral and Cell-Mediated Immunity Elicited by Gene Gun Immunization

article

Epidermal inoculation of Leishmania-antigen by gold bombardment results in a chronic form of leishmaniasis

scientific article published on 07 August 2006

Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer

scientific article published in Scientific Reports

Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen

scientific article (publication date: May 2016)

From sequence to antibody: genetic immunisation is suitable to generate antibodies against a rare plant membrane protein, the KAT 1 channel

scientific article

Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines

article

Gene gun immunization with clinically relevant allergens aggravates allergen induced pathology and is contraindicated for allergen immunotherapy

scientific article published on 30 October 2006

Generation and Evaluation of Prophylactic mRNA Vaccines Against Allergy

scientific article published in January 2017

Generation of hypoallergenic DNA vaccines by forced ubiquitination: Preventive and therapeutic effects in a mouse model of allergy

scientific article published on 11 May 2006

Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy

scientific article published on 10 November 2012

Genetic immunization: new ways for protective and therapeutic vaccines against allergic diseases

scientific article

Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein

scientific article

Genetic vaccination approaches against malaria based on the circumsporozoite protein.

scientific article published on January 2006

IL-31 transgenic mice show reduced allergen-induced lung inflammation

scientific article published on 10 July 2020

Immune Repertoire Profiling Reveals that Clonally Expanded B and T Cells Infiltrating Diseased Human Kidneys Can Also Be Tracked in Blood

scientific article published on 23 November 2015

Immune responses after immunization with plasmid DNA encoding Bet v 1, the major allergen of birch pollen

article

Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization.

scientific article published on 6 June 2006

Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens

scientific article published on 8 August 2009

Improvement of the immune response against plasmid DNA encoding OspC of Borrelia by an ER-targeting leader sequence

scientific article published on 01 December 1999

Influence of protein fold stability on immunogenicity and its implications for vaccine design

scientific article published on 14 March 2017

Inhibition of type I allergic responses with nanogram doses of replicon-based DNA vaccines.

scientific article published on July 2006

Is genetic vaccination against allergy possible?

scientific article

Isoforms of the Major Allergen of Birch Pollen Induce Different Immune Responses after Genetic Immunization

article

Laser microporation of the skin: prospects for painless application of protective and therapeutic vaccines.

scientific article

Laser-facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation

scientific article published on 27 December 2019

Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma

scientific article published on 03 July 2020

Mast cells and γδ T cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization

scientific article published on 04 December 2019

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

scientific article published on 08 October 2019

Natural clinical tolerance to peanut in African patients is caused by poor allergenic activity of peanut IgE.

scientific article

Natural protective immunity against grass pollen allergy is maintained by a diverse spectrum of response types.

scientific article published on 31 August 2017

New approaches to transcutaneous immunotherapy: targeting dendritic cells with novel allergen conjugates.

scientific article published on December 2013

Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern

scientific article published on 15 May 2015

Potential of nanoparticles for allergen-specific immunotherapy - use of silica nanoparticles as vaccination platform

scientific article

Prophylactic mRNA Vaccination against Allergy Confers Long-Term Memory Responses and Persistent Protection in Mice

scientific article published on 18 October 2015

Prophylactic mRNA vaccination against allergy

scientific article published on December 2010

Protective and therapeutic DNA vaccination against allergic diseases

scientific article published in January 2014

Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy

scientific article published on 3 March 2006

Protein antigen delivery by gene gun-mediated epidermal antigen incorporation (EAI).

scientific article published in January 2013

Removal of the circumsporozoite protein (CSP) glycosylphosphatidylinositol signal sequence from a CSP DNA vaccine enhances induction of CSP-specific Th2 type immune responses and improvesprotection against malaria infection

scientific article published in March 2001

Replicase-based plasmid DNA shows anti-tumor activity ⬇️

scientific article published on March 28, 2011

Role of the polypeptide backbone and post-translational modifications in cross-reactivity of Art v 1, the major mugwort pollen allergen

scientific article

Skin vaccination via fractional infrared laser ablation - Optimization of laser-parameters and adjuvantation.

scientific article

Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy

scientific article published on 14 September 2017

T cell epitopes of the timothy grass pollen allergen Phl p 5 of mice and men and the detection of allergen-specific T cells using Class II Ultimers

scientific article published on 03 April 2012

The Influence of Ketogenic Diets on Psoriasiform-Like Skin Inflammation

scientific article published on 17 October 2019

The extent of the uptake of plasmid into the skin determines the immune responses induced by a DNA vaccine applied topically onto the skin.

scientific article

The fold variant BM4 is beneficial in a therapeutic Bet v 1 mouse model

scientific article published on 23 September 2013

The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine ⬇️

scientific article published on August 14, 2013

Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS

scientific article published on 22 October 2020

Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores ⬇️

scientific article published on December 27, 2012

Transcutaneous immunotherapy via laser-generated micropores efficiently alleviates allergic asthma in Phl p 5-sensitized mice

scientific article

Transcutaneous vaccination via laser microporation

scientific article

Treatment of 1-methyl-1-nitrosourea-induced mammary tumours with immunostimulatory CpG motifs and 13-cis retinoic acid in female rats: histopathological study.

scientific article published in September 2003

What is the antiallergic potential of DNA vaccination?

scientific article published on 22 June 2015

mRNA vaccination as a safe approach for specific protection from type I allergy.

scientific article published on January 2012

List of works by Richard Weiss

A DNA vaccine encoding the outer surface protein C from Borrelia burgdorferi is able to induce protective immune responses

Allergen microarray detects high prevalence of asymptomatic IgE sensitizations to tropical pollen-derived carbohydrates

Allergens are not pathogens: why immunization against allergy differs from vaccination against infectious diseases

Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.

Arabidopsis MAP-Kinase 3 Phosphorylates UDP-Glucose Dehydrogenase: a Key Enzyme Providing UDP-Sugar for Cell Wall Biosynthesis

Behead and live long or the tale of cathepsin L.

Bicistronic expression plasmid encoding allergen and anti-IgE single chain variable fragment antibody as a novel DNA vaccine for allergy therapy and prevention

C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria.

Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver.

Clinical significance of HLA-E*0103 homozygosity on survival after allogeneic hematopoietic stem-cell transplantation

Confirmation of immuno-reactivity of the recombinant major birch pollen allergen Bet v 1a by affinity-CIEF.

DNA and mRNA vaccination against allergies

DNA immunization in vivo down-regulates nuclear all-trans retinoic acid receptors in mouse spleen cells.

Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development.

Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.

Differential effects of C3d on the immunogenicity of gene gun vaccines encoding Plasmodium falciparum and Plasmodium berghei MSP1(42).

Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin

Epidermal Langerhans Cells Are Dispensable for Humoral and Cell-Mediated Immunity Elicited by Gene Gun Immunization

Epidermal inoculation of Leishmania-antigen by gold bombardment results in a chronic form of leishmaniasis

Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer

Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen

From sequence to antibody: genetic immunisation is suitable to generate antibodies against a rare plant membrane protein, the KAT 1 channel

Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines

Gene gun immunization with clinically relevant allergens aggravates allergen induced pathology and is contraindicated for allergen immunotherapy

Generation and Evaluation of Prophylactic mRNA Vaccines Against Allergy

Generation of hypoallergenic DNA vaccines by forced ubiquitination: Preventive and therapeutic effects in a mouse model of allergy

Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy

Genetic immunization: new ways for protective and therapeutic vaccines against allergic diseases

Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein

Genetic vaccination approaches against malaria based on the circumsporozoite protein.

IL-31 transgenic mice show reduced allergen-induced lung inflammation

Immune Repertoire Profiling Reveals that Clonally Expanded B and T Cells Infiltrating Diseased Human Kidneys Can Also Be Tracked in Blood

Immune responses after immunization with plasmid DNA encoding Bet v 1, the major allergen of birch pollen

Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization.

Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens

Improvement of the immune response against plasmid DNA encoding OspC of Borrelia by an ER-targeting leader sequence

Influence of protein fold stability on immunogenicity and its implications for vaccine design

Inhibition of type I allergic responses with nanogram doses of replicon-based DNA vaccines.

Is genetic vaccination against allergy possible?

Isoforms of the Major Allergen of Birch Pollen Induce Different Immune Responses after Genetic Immunization

Laser microporation of the skin: prospects for painless application of protective and therapeutic vaccines.

Laser-facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation

Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma

Mast cells and γδ T cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

Natural clinical tolerance to peanut in African patients is caused by poor allergenic activity of peanut IgE.

Natural protective immunity against grass pollen allergy is maintained by a diverse spectrum of response types.

New approaches to transcutaneous immunotherapy: targeting dendritic cells with novel allergen conjugates.

Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern

Potential of nanoparticles for allergen-specific immunotherapy - use of silica nanoparticles as vaccination platform

Prophylactic mRNA Vaccination against Allergy Confers Long-Term Memory Responses and Persistent Protection in Mice

Prophylactic mRNA vaccination against allergy

Protective and therapeutic DNA vaccination against allergic diseases

Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy

Protein antigen delivery by gene gun-mediated epidermal antigen incorporation (EAI).

Removal of the circumsporozoite protein (CSP) glycosylphosphatidylinositol signal sequence from a CSP DNA vaccine enhances induction of CSP-specific Th2 type immune responses and improvesprotection against malaria infection

Replicase-based plasmid DNA shows anti-tumor activity ⬇️

Role of the polypeptide backbone and post-translational modifications in cross-reactivity of Art v 1, the major mugwort pollen allergen

Skin vaccination via fractional infrared laser ablation - Optimization of laser-parameters and adjuvantation.

Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy

T cell epitopes of the timothy grass pollen allergen Phl p 5 of mice and men and the detection of allergen-specific T cells using Class II Ultimers

The Influence of Ketogenic Diets on Psoriasiform-Like Skin Inflammation

The extent of the uptake of plasmid into the skin determines the immune responses induced by a DNA vaccine applied topically onto the skin.

The fold variant BM4 is beneficial in a therapeutic Bet v 1 mouse model

The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine ⬇️

Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS

Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores ⬇️

Transcutaneous immunotherapy via laser-generated micropores efficiently alleviates allergic asthma in Phl p 5-sensitized mice

Transcutaneous vaccination via laser microporation

Treatment of 1-methyl-1-nitrosourea-induced mammary tumours with immunostimulatory CpG motifs and 13-cis retinoic acid in female rats: histopathological study.

What is the antiallergic potential of DNA vaccination?

mRNA vaccination as a safe approach for specific protection from type I allergy.