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List of works by Kasper M Rouschop

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

scientific article

CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy

scientific article published in March 2004

CD44 disruption prevents degeneration of the capillary network in obstructive nephropathy via reduction of TGF-beta1-induced apoptosis

scientific article published in February 2006

CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy

scientific article published on 11 September 2013

Canonical autophagy does not contribute to cellular radioresistance.

scientific article

Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial

scientific article published on 20 September 2020

Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment

scientific article

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

scientific article published on 12 June 2011

EGFR signaling and autophagy dependence for growth, survival, and therapy resistance

scientific article published on 13 December 2013

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition

scientific article

Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection

scientific article

GABARAPL1 is required for increased EGFR membrane expression during hypoxia

scientific article published on 8 July 2015

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High dose rate and flattening filter free irradiation can be safely implemented in clinical practice

scientific article

Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells.

scientific article

Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response

scientific article published on 29 June 2009

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

scientific article published on 17 September 2013

Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.

scientific article

Impact of supervised gene signatures of early hypoxia on patient survival

scientific article published on 25 May 2007

Ischemia–reperfusion treatment: opportunities point to modulation of the inflammatory response

scientific article published on 01 June 2008

Learning radiation oncology in Europe: Results of the ESTRO multidisciplinary survey.

scientific article published on 8 February 2018

Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion

scientific article published on 19 October 2010

Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy

scientific article published on 9 April 2014

Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A

scientific article published on 29 April 2015

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

scientific article published on 7 March 2013

Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.

scientific article published on 24 May 2007

Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection

scientific article published on 01 October 2005

Protection against renal ischemia reperfusion injury by CD44 disruption

scientific article

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress

article

Regulation of autophagy through multiple independent hypoxic signaling pathways.

scientific article published on May 2009

Renal expression of CD44 correlates with acute renal allograft rejection

scientific article published on 26 July 2006

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

scientific article

Secretion of pro-angiogenic extracellular vesicles during hypoxia is dependent on the autophagy-related protein GABARAPL1

scientific article published on 01 December 2021

Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase

scientific article

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

scientific article

The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment

scientific article published on 16 July 2009

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

scientific article

The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis

scientific article

Tissue-Type Plasminogen Activator Modulates Inflammatory Responses and Renal Function in Ischemia Reperfusion Injury

article

Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.

scientific article published on 24 August 2011

Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract

scientific article

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