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List of works by Lewis H Mervin

A Nano-MgO and Ionic Liquid-Catalyzed 'Green' Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51).

scientific article published on 15 October 2015

Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic Signature

scientific article published in 2022

Comparison of Scaling Methods to Obtain Calibrated Probabilities of Activity for Protein-Ligand Predictions

scientific article published on 21 September 2020

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

scientific article published on 30 December 2017

Current Trends in Drug Sensitivity Prediction

scientific article published on 26 October 2016

Extending in Silico Protein Target Prediction Models to Include Functional Effects.

scientific article published on 11 June 2018

Leveraging heterogeneous data from GHS toxicity annotations, molecular and protein target descriptors and Tox21 assay readouts to predict and rationalise acute toxicity.

scientific article published on 31 May 2019

Novel Adamantanyl-Based Thiadiazolyl Pyrazoles Targeting EGFR in Triple-Negative Breast Cancer.

scientific article published on 28 December 2016

Orthologue chemical space and its influence on target prediction

scientific article published on 26 August 2017

Target prediction utilising negative bioactivity data covering large chemical space

scientific article (publication date: 2015)

Toward Understanding the Cold, Hot, and Neutral Nature of Chinese Medicines Using in Silico Mode-of-Action Analysis

scientific article

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

scientific article

Uncertainty quantification in drug design

scientific article published on 27 November 2020

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