List of works - Christoph Helma

A Large-Scale Empirical Evaluation of Cross-Validation and External Test Set Validation in (Q)SAR.

scientific article published on 3 June 2013

A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay

scientific article

A survey of the Predictive Toxicology Challenge 2000-2001.

scientific article

Automated and reproducible read-across like models for predicting carcinogenic potency

scientific article published on 15 July 2014

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions

scientific article

Classification of cytochrome p(450) activities using machine learning methods.

scientific article

Collaborative development of predictive toxicology applications

scientific article

Combinatorial QSAR modeling of human intestinal absorption

scientific article published on 29 December 2010

Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure activity relationships of noncongeneric compounds

scientific article

Development of decision tree models for substrates, inhibitors, and inducers of p-glycoprotein

scientific article

Enhanced clastogenicity of contaminated groundwater following UV irradiation detected by the Tradescantia micronucleus assay

scientific article published on 01 March 1994

Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells

scientific article published on 01 July 2000

Fragment generation and support vector machines for inducing SARs.

scientific article published in July 2002

Genotoxic effects of heavy metals: Comparative investigation with plant bioassays

article

Genotoxic effects of the chlorinated hydroxyfuranones 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and 3,4-dichloro-5-hydroxy-2[5H]-furanone in Tradescantia micronucleus assays

scientific article published in March 1995

In silico predictive toxicology: the state-of-the-art and strategies to predict human health effects.

scientific article

Innovative Strategies to Develop Chemical Categories Using a Combination of Structural and Toxicological Properties

scientific article

Investigations on genotoxic effects of groundwater from the Mitterndorfer Senke and from the vicinity of Wiener Neustadt

scientific article published in December 1998

Knowledge discovery and data mining in toxicology

scientific article

Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity

scientific article published on 24 May 2006

Molecular feature mining in HIV data

article

Nano-Lazar: Read across Predictions for Nanoparticle Toxicities with Calculated and Measured Properties

scientific article

Prediction of adverse drug reactions using decision tree modeling

scientific article

Prediction of chemical toxicity with local support vector regression and activity-specific kernels

article

Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives

scientific article published on April 2009

Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells

scientific article published on May 1999

Statistical evaluation of the Predictive Toxicology Challenge 2000-2001.

scientific article

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

scientific article (publication date: 2013)

The expanding role of predictive toxicology: an update on the (Q)SAR models for mutagens and carcinogens

scientific article published on January 2007

Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment.

scientific article

Validation of counter propagation neural network models for predictive toxicology according to the OECD principles: a case study

scientific article published in June 2006

lazar: a modular predictive toxicology framework

scientific article published on 09 April 2013

List of works by Christoph Helma

A Large-Scale Empirical Evaluation of Cross-Validation and External Test Set Validation in (Q)SAR.

A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay

A survey of the Predictive Toxicology Challenge 2000-2001.

Automated and reproducible read-across like models for predicting carcinogenic potency

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions

Classification of cytochrome p(450) activities using machine learning methods.

Collaborative development of predictive toxicology applications

Combinatorial QSAR modeling of human intestinal absorption

Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure activity relationships of noncongeneric compounds

Development of decision tree models for substrates, inhibitors, and inducers of p-glycoprotein

Enhanced clastogenicity of contaminated groundwater following UV irradiation detected by the Tradescantia micronucleus assay

Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells

Fragment generation and support vector machines for inducing SARs.

Genotoxic effects of heavy metals: Comparative investigation with plant bioassays

Genotoxic effects of the chlorinated hydroxyfuranones 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and 3,4-dichloro-5-hydroxy-2[5H]-furanone in Tradescantia micronucleus assays

In silico predictive toxicology: the state-of-the-art and strategies to predict human health effects.

Innovative Strategies to Develop Chemical Categories Using a Combination of Structural and Toxicological Properties

Investigations on genotoxic effects of groundwater from the Mitterndorfer Senke and from the vicinity of Wiener Neustadt

Knowledge discovery and data mining in toxicology

Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity

Molecular feature mining in HIV data

Nano-Lazar: Read across Predictions for Nanoparticle Toxicities with Calculated and Measured Properties

Prediction of adverse drug reactions using decision tree modeling

Prediction of chemical toxicity with local support vector regression and activity-specific kernels

Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives

Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells

Statistical evaluation of the Predictive Toxicology Challenge 2000-2001.

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

The expanding role of predictive toxicology: an update on the (Q)SAR models for mutagens and carcinogens

Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment.

Validation of counter propagation neural network models for predictive toxicology according to the OECD principles: a case study

lazar: a modular predictive toxicology framework