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List of works by William H. Colledge

A LacZ-based transgenic mouse for detection of somatic gene repair events in vivo.

scientific article published in September 2004

A comparison of gene repair strategies in cell culture using a lacZ reporter system

scientific article published in September 2003

A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo

scientific article published in September 2003

A comparison of topoisomerase I activity in normal and transformed cells.

scientific article published in March 1986

A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3- secretion.

scientific article published on December 1997

Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNA.

scientific article published on February 1987

Acetylcholine induces cytosolic Ca2+ mobilization in isolated distal colonic crypts from normal and cystic fibrosis mice.

scientific article published in March 2001

Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

scientific article published on 3 July 2002

Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart.

scientific article published on January 2007

Aspartate138 is required for the high-affinity ligand binding site but not for the low-affinity binding site of the beta1-adrenoceptor

scientific article

Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers

scientific article published on 2 April 2004

Calcium-activated chloride conductance is not increased in pancreatic duct cells of CF mice

scientific article published on 01 May 1995

Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse.

scientific article published on 4 September 2012

Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice

article

Comparison of protein transduction domains in mediating cell delivery of a secreted CRE protein.

scientific article published on 8 January 2008

Correction: Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo.

scientific article

Crouzon-like craniofacial dysmorphology in the mouse is caused by an insertional mutation at the Fgf3/Fgf4 locus

scientific article published in June 1998

Cystic fibrosis gene therapy.

scientific article

Cystic fibrosis mouse with intestinal obstruction

scientific article published on 01 September 1992

Defending sperm function

scientific article

Definition of the hypothalamic GnRH pulse generator in mice

scientific article published on 6 November 2017

DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs

scientific article published on February 2002

Disruption of murine α-enolase by a retroviral gene trap results in early embryonic lethality ⬇️

scientific article published on June 1, 1998

Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting

scientific article published in July 1992

Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons

scientific article published on 4 December 2009

Distribution of kisspeptin neurones in the adult female mouse brain

scientific article

Does Kisspeptin Signaling have a Role in the Testes?

scientific article published on 30 December 2013

Ducts isolated from the pancreas of CFTR-null mice secrete fluid

scientific article published on 5 August 2009

Effect of acute saline volume expansion in the anaesthetised DeltaF508 cystic fibrosis mouse

scientific article published on 31 July 2001

Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.

scientific article

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome

scientific article published on 15 February 2007

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3

scientific article published on 05 October 2006

Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex.

scientific article published on March 2001

Enhancement of gene delivery to human airway epithelial cells in vitro using a peptide from the polyoma virus protein VP1.

scientific article published in June 2005

Eomesodermin is required for mouse trophoblast development and mesoderm formation

scientific journal article

Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.

scientific article published in February 2011

GPR54 and kisspeptins.

scientific article published on January 2008

GPR54 and puberty

scientific article

Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens

scientific article published on 14 December 2010

How much kissing is required for fertility?

scientific article

Hyperalgesic activity of kisspeptin in mice.

scientific article published on 23 November 2011

Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.

scholarly article

Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging

scientific journal article

Inactivation of the murine cftr gene abolishes cAMP-mediated but not Ca(2+)-mediated secretagogue-induced volume decrease in small-intestinal crypts

scientific article published in December 1993

Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter.

scientific article

Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence.

scientific article published on January 2001

Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor

scientific article

Insulin-like peptide 5 is an orexigenic gastrointestinal hormone

scientific journal article

International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function

scientific article

Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.

scientific article

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors

scientific article

Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion

scientific article published in February 2006

Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis

scientific article published in October 1994

Kiss1 mutant placentas show normal structure and function in the mouse

scientific article

Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals.

scientific article published on May 2008

Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54.

scientific article

Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus

scientific article published in December 2011

Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA. ⬇️

scientific article published on June 2010

Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation

scientific article published in January 2012

Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.

scientific article published in August 2008

Kv4.2 channel activity controls intrinsic firing dynamics of arcuate kisspeptin neurons

scientific article published on 6 December 2017

Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.

scientific article

Leptin-dependent neuronal NO signaling in the preoptic hypothalamusfacilitates reproduction.

scientific article

Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse

scientific article published on 27 March 2019

Markedly reduced effects of (-)-isoprenaline but not of (-)-CGP12177 and unchanged affinity of beta-blockers at Gly389-beta1-adrenoceptors compared to Arg389-beta1-adrenoceptors.

scientific article published on 22 March 2004

Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo.

scientific article

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens ⬇️

scientific article published on April 1, 1998

Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

scholarly article

Mll5 is required for normal spermatogenesis

scientific article (publication date: 2011)

Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis

scientific journal article

Mouse models of cystic fibrosis: phenotypic analysis and research applications

scientific article published on June 2011

Mouse models to study the central regulation of puberty.

scientific article published on 18 January 2010

Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium

scientific article published in September 2001

Murine CFTR channel and its role in regulatory volume decrease of small intestine crypts

scientific article

Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice

scientific journal article

Optimisation of real-time quantitative RT-PCR for the evaluation of non-viral mediated gene transfer to the airways.

scientific article published in October 2002

Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice.

scientific article published on December 2005

Production of a severe cystic fibrosis mutation in mice by gene targeting

scientific article published in May 1993

Propranolol enhances cell cycle-related gene expression in pressure overloaded hearts.

scientific article published on December 2011

Salmonella typhi uses CFTR to enter intestinal epithelial cells.

scientific article

Search of the 5' untranslated region of the human cardiac actin gene for segments controlling translation.

scientific article published on September 1990

Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a

scientific journal article

Splenomegaly and modified erythropoiesis in KLF13-/- mice

scientific journal article

Stella is a maternal effect gene required for normal early development in mice

scientific article

Steroid hormone enhancement of gene delivery to a human airway epithelial cell line in vitro and mouse airways in vivo.

scientific article

Synthetic chemerin-derived peptides suppress inflammation through ChemR23

scientific article

The GPR54 gene as a regulator of puberty

scientific article (publication date: 23 October 2003)

The cyclin A1-CDK2 complex regulates DNA double-strand break repair.

scientific article published on October 2004

The intrinsic Cl- conductance of mouse kidney cortex brush-border membrane vesicles is not related to CFTR.

scientific article published in September 1997

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

scientific article

The neuroendocrine regulation of the mammalian reproductive axis. Introduction

scientific article published in November 2013

The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

scientific article

The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse

scientific article

The role of kisspeptin signaling in reproduction.

scientific article published on August 2010

The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice

scientific article published on 02 April 2010

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

scientific article

Transgenic mouse models to study Gpr54/kisspeptin physiology

scientific article published on 15 May 2008

Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model

scientific article

Voltage dependence of the Ca(2+)-activated K(+) channel K(Ca)3.1 in human erythroleukemia cells.

scientific article published on 13 February 2013

X-ray microanalysis of airway surface liquid in the mouse.

scientific article published on 23 December 2004

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