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List of works by Javier Vitorica

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.

scientific article published on 22 October 2011

Absence of association between delta and gamma2 subunits in native GABA(A) receptors from rat brain

scientific article published in April 1998

Activity-dependent neuroprotective protein (ADNP) expression in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease

scientific article published on 21 October 2009

Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

scientific article published on April 2011

Age-related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects.

scientific article published on 19 November 2008

Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex

scientific article published in October 1996

Aging-related subunit expression changes of the GABAA receptor in the rat hippocampus.

scientific article published in September 1996

Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease

scientific article published on 07 December 2020

Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death.

scientific article published on 12 April 2016

Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus

scientific article published in January 2010

Cellular environment facilitates protein accumulation in aged rat hippocampus.

scientific article published on 17 June 2005

Comparison between developmental and senescent changes in enzyme activities linked to energy metabolism in rat heart.

scientific article published in June 1981

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

scientific article published on 22 November 2012

Distribution of the gamma-aminobutyric acid(A) receptor complex alpha 5 subunit in chick brain. An immunocytochemical and autoradiographic study

scientific article published on 01 September 2000

Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease

scientific article published on 3 November 2005

Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice

scientific article published in January 2009

GABAA and alpha-amino-3-hydroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus

scientific article published on 01 June 2000

Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.

scientific article published in November 2008

Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice.

scientific article

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus.

scientific article

Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.

scientific article published on 27 December 2013

Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons

scientific article published on 31 July 2007

Molecular and pharmacological characterization of native cortical gamma-aminobutyric acidA receptors containing both alpha1 and alpha3 subunits

scientific article

Non-productive angiogenesis disassembles Aß plaque-associated blood vessels

scientific article published on 25 May 2021

Pharmacological properties of the GABA(A) receptor complex from brain regions of (hypoemotional) Roman high- and (hyperemotional) low-avoidance rats

scientific article published in July 1998

Postnatal development of the α1 containing GABAA receptor subunit in rat hippocampus

article

Prevalence between different alpha subunits performing the benzodiazepine binding sites in native heterologous GABA(A) receptors containing the alpha2 subunit

scientific article

Rapid PCR-mediated synthesis of competitor molecules for accurate quantification of beta(2) GABA(A) receptor subunit mRNA.

scientific article published in December 2001

Regional difference in inflammatory response to LPS-injection in the brain: role of microglia cell density.

scientific article

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology.

scientific article published on 18 October 2011

Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection

scientific article published on 18 May 2006