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List of works by David Sevillano Fernández

A new biocompatible and antibacterial phosphate free glass-ceramic for medical applications.

scientific article

A pharmacodynamic approach to antimicrobial activity in serum and epithelial lining fluid against in vivo-selected Streptococcus pneumoniae mutants and association with clinical failure in pneumonia

scientific article published on 16 June 2006

Activity of different antimicrobial agents against penicillin-resistant Streptococcus pneumoniae

scientific article published in December 2001

Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii

scientific article published in December 2001

Activity of serum concentrations of daptomycin vs. vancomycin against vancomycin-susceptible and resistant Enterococcus faecium in the presence of albumin physiological concentrations: an in vitro pharmacodynamic simulation

scientific article published on 21 May 2008

Activity of simulated serum concentrations of daptomycin versus vancomycin during the first 24h of treatment in the presence of physiological albumin concentrations against vancomycin-susceptible, -tolerant or -intermediate-resistant Staphylococcus a

scientific article published on 01 April 2011

Alterations of the penicillin-binding proteins and murM alleles of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin in Spain

scientific article published on 20 December 2005

Are β-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view?

scientific article published on 06 March 2007

Azithromycin iv pharmacodynamic parameters predicting Streptococcus pneumoniae killing in epithelial lining fluid versus serum: an in vitro pharmacodynamic simulation

scientific article published on 14 April 2006

Bactericidal activity of amoxicillin against non-susceptible Streptococcus pneumoniae in an in vitro pharmacodynamic model simulating the concentrations obtained with the 2000/125 mg sustained-release co-amoxiclav formulation

scientific article published on 15 October 2004

Bactericidal activity of moxifloxacin against multidrug-resistant Streptoccocus pneumoniae at clinically achievable serum and epithelial lining fluid concentrations compared with three other antimicrobials

scientific article published in October 2004

Beta-lactam activity against penicillin-resistant Streptococcus pneumoniae strains exhibiting higher amoxicillin versus penicillin minimum inhibitory concentration values: an in vitro pharmacodynamic simulation.

scientific article

Cefditoren and Ceftriaxone Enhance Complement-Mediated Immunity in the Presence of Specific Antibodies against Antibiotic-Resistant Pneumococcal Strains ⬇️

scientific article published on September 5, 2012

Cefditoren versus ceftazidime in inducer-substrate combinations for the evaluation of AmpC production in a disc approximation test.

scientific article published in June 2010

Cidal activity of oral third-generation cephalosporins against Streptococcus pneumoniae in relation to cefotaxime intrinsic activity.

scientific article

Clinical and Antimicrobial Efficacy of a Silver Foam Dressing With Silicone Adhesive in Diabetic Foot Ulcers With Mild Infection

scientific article published on 05 August 2019

Colonial architecture and growth dynamics of Staphylococcus aureus resistant to methicillin.

scientific article

Combinations of PBPs and MurM protein variants in early and contemporary high-level penicillin-resistant Streptococcus pneumoniae isolates in Spain

article

Correlation between in vitro and in vivo activity of levofloxacin and moxifloxacin against pneumococcal strains with different susceptibilities to fluoroquinolones

scientific article published on 9 March 2006

Decrease in bacterial load versus resistance selection of pneumococcal subpopulations by beta-lactam physiological concentrations over time: an in vitro pharmacodynamic simulation

scientific article

Effect of opsonophagocytosis mediated by specific antibodies on the co-amoxiclav serum bactericidal activity against Streptococcus pneumoniae after administration of a single oral dose of pharmacokinetically enhanced 2000/125 mg co-amoxiclav to heal

scientific article

Effect of protein binding on the activity of voriconazole alone or combined with anidulafungin against Aspergillus spp. using a time-kill methodology.

scientific article published in March 2012

Effect of the Medium Composition on the Zn2+ Lixiviation and the Antifouling Properties of a Glass with a High ZnO Content

scientific article published on 13 February 2017

Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub: Cross-over trial

scientific article published on 01 October 2018

Effects of antimicrobials on the competitive growth of Streptococcus pneumoniae: a pharmacodynamic in vitro model approach to selection of resistant populations

scientific article published on 30 July 2006

Effects of human albumin and serum on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumoniae.

scientific article published on 4 May 2007

Efficacy of Preoperative and Intraoperative Skin and Nail Surgical Preparation of the Foot in Reducing Bacterial Load ⬇️

scientific article published on August 1, 2010

Efficacy of intraoperative antiseptic scrub after nail removal surgery

scientific article published on 7 August 2012

Efficacy of simulated cefditoren versus amoxicillin-clavulanate free concentrations in countering intrastrain ftsI gene diffusion in Haemophilus influenzae.

scientific article

Evaluation of two in vitro pharmacodynamic simulation models: microfiltration versus centrifugation-filtration

scientific article

Evolving architectural patterns in microbial colonies development

scientific article published on 30 December 2010

Exposure-response analysis of tigecycline in pharmacodynamic simulations using different size inocula of target bacteria.

scientific article published on 11 May 2010

High protein binding and cidal activity against penicillin-resistant S. pneumoniae: a cefditoren in vitro pharmacodynamic simulation

scientific article

In vitro activity of clarithromycin against penicillin-susceptible and penicillin-resistant strains of Streptococcus pneumoniae in a pharmacodynamic simulation model.

scientific article

In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin

scientific article published in May 2004

In vitro combined effect of co-amoxiclav concentrations achievable in serum after a 2000/125 mg oral dose, and polymorphonuclear neutrophils against strains of Streptococcus pneumoniae exhibiting decreased susceptibility to amoxicillin

scientific article

In vitro effect of physiological concentrations of human albumin on the antibacterial activity of tigecycline.

scientific article published on 16 October 2009

In vitro effect of the presence of human albumin or human serum on the bactericidal activity of daptomycin against strains with the main resistance phenotypes in Gram-positives

scientific article published on 05 April 2007

Influence of different resistance traits on the competitive growth of Haemophilus influenzae in antibiotic-free medium and selection of resistant populations by different {beta}-lactams: an in vitro pharmacodynamic approach

scientific article published on 22 March 2009

Influence of media and testing methodology on susceptibility to tigecycline of Enterobacteriaceae with reported high tigecycline MIC.

scientific article published on 29 March 2010

Influence of the MBC/MIC ratio on the antibacterial activity of vancomycin versus linezolid against methicillin-resistant Staphylococcus aureus isolates in a pharmacodynamic model simulating serum and soft tissue interstitial fluid concentrations re

scientific article published on 14 May 2013

Influence of the displacement of protein binding by ibuprofen in the activity of a third-generation cephalosporin against Streptococcus pneumoniae

scientific article published in December 2006

Inhibitory effect on in vitro Streptococcus oralis biofilm of a soda-lime glass containing silver nanoparticles coating on titanium alloy

scientific article

Is there a pharmacodynamic need for the use of continuous versus intermittent infusion with ceftazidime against Pseudomonas aeruginosa? An in vitro pharmacodynamic model

scientific article published on 13 January 2005

Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration

scientific article published on 05 February 2014

Monte Carlo simulation describing the pharmacodynamic profile of cefditoren in plasma from healthy volunteers

scientific article published on 4 January 2008

Pharmacodynamics of simulated total versus free-drug serum concentrations of a low versus a high protein bound third-generation oral cephalosporin (Cefpodoxime versus cefditoren) against Streptococcus pneumoniae

scientific article published on 01 June 2007

Preoperative skin and nail preparation of the foot: comparison of the efficacy of 4 different methods in reducing bacterial load

scientific article published on 7 August 2009

Prevalence of Staphylococcus spp. nasal colonization among doctors of podiatric medicine and associated risk factors in Spain.

scientific article published on 17 February 2018

Protection of Enterococcus faecalis in mixed cultures with carbapenemase-producing Escherichia coli and Bacteroide fragilis: effect of the bacterial load

scientific article published in September 2013

Survival of human pathogenic bacteria in different types of natural mineral water.

scientific article published in September 2012

The Role of PPARγ on Restoration of Colonic Homeostasis After Experimental Stress-Induced Inflammation and Dysfunction

scientific article published on 21 February 2007

The birth of the greatest invention of the 20th century

scientific article published in September 2007

Tinidazole inhibitory and cidal activity against anaerobic periodontal pathogens

scientific article

Total nail ablation for onychodystrophy with optimized gauze-phenol application

scientific article published on 17 February 2010

Ultrasound-assisted debridement of neuroischaemic diabetic foot ulcers, clinical and microbiological effects: a case series

scientific article published on 01 May 2018

Urine bactericidal activity against Escherichia coli isolates exhibiting different resistance phenotypes/genotypes in an in vitro pharmacodynamic model simulating urine concentrations obtained after oral administration of a 400-milligram single dose

scientific article published on 26 December 2007

Urine bactericidal activity against resistant Escherichia coli in an in vitro pharmacodynamic model simulating urine concentrations obtained after 2000/125 mg sustained-release co-amoxiclav and 400 mg norfloxacin administration

scientific article published on 21 February 2006

[An update on the susceptibility of Stenotrophomonas maltophilia]

scientific article

[Are pharmacodynamics a useful tool for the prevention of resistance?]

scientific article

influence of TEM-1 beta-lactamase on the pharmacodynamic activity of simulated total versus free-drug serum concentrations of cefditoren (400 milligrams) versus amoxicillin-clavulanic acid (2,000/125 milligrams) against Haemophilus influenzae strain

scientific article

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