List of works - Giovanna Di Nardo

Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints

scientific article published on 17 January 2020

Catalytic properties of catechol 1,2-dioxygenase from Acinetobacter radioresistens S13 immobilized on nanosponges

scientific article published on 14 July 2009

Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition

scientific article published on 22 August 2011

Drug–drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4

scientific article published in August 2012

Effects of surface hydrophobicity on the catalytic iron ion retention in the active site of two catechol 1,2-dioxygenase isoenzymes

scientific article published in December 2004

Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs.

scientific article published on 7 June 2012

Engineering heme binding sites in monomeric rop.

scientific article published on 17 January 2009

Fluorescence detection of ligand binding to labeled cytochrome P450BM3

scientific article published in 2012

Human aromatase: perspectives in biochemistry and biotechnology.

scientific article published on January 2013

Hydroxylation of non-substituted polycyclic aromatic hydrocarbons by cytochrome P450 BM3 engineered by directed evolution.

scientific article

Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

scientific article

Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras

scientific article published in November 2018

Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor

scientific article published on 05 August 2020

Optimization of the Bacterial Cytochrome P450 BM3 System for the Production of Human Drug Metabolites ⬇️

scientific article published on November 28, 2012

Peroxide-driven catalysis of the heme domain of A. radioresistens cytochrome P450 116B5 for sustainable aromatic rings oxidation and drug metabolites production

scientific article published on 29 August 2019

Protein and electrode engineering for the covalent immobilization of P450 BMP on gold.

scientific article

Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase

scientific article

Structural roles of the active site iron(III) ions in catechol 1,2-dioxygenases and differential secondary structure changes in isoenzymes A and B from Acinetobacter radioresistens S13.

scientific article published in November 2004

Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates

scientific article published in November 2012

List of works by Giovanna Di Nardo

Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints

Catalytic properties of catechol 1,2-dioxygenase from Acinetobacter radioresistens S13 immobilized on nanosponges

Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition

Drug–drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4

Effects of surface hydrophobicity on the catalytic iron ion retention in the active site of two catechol 1,2-dioxygenase isoenzymes

Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs.

Engineering heme binding sites in monomeric rop.

Fluorescence detection of ligand binding to labeled cytochrome P450BM3

Human aromatase: perspectives in biochemistry and biotechnology.

Hydroxylation of non-substituted polycyclic aromatic hydrocarbons by cytochrome P450 BM3 engineered by directed evolution.

Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras

Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor

Optimization of the Bacterial Cytochrome P450 BM3 System for the Production of Human Drug Metabolites ⬇️

Peroxide-driven catalysis of the heme domain of A. radioresistens cytochrome P450 116B5 for sustainable aromatic rings oxidation and drug metabolites production

Protein and electrode engineering for the covalent immobilization of P450 BMP on gold.

Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase

Structural roles of the active site iron(III) ions in catechol 1,2-dioxygenases and differential secondary structure changes in isoenzymes A and B from Acinetobacter radioresistens S13.

Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates