List of works - Nikolaus Thuille

Bactericidal activity of herbal extracts.

scientific article

Comment on "PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation"

scientific article published on 01 April 2006

Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.

scientific article

Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.

scientific article

Defective IgG2a/2b class switching in PKC alpha-/- mice

scientific article published on 01 May 2006

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice

scientific article published on 17 January 2012

Development of a fast and sensitive method to study transcription factor activation under endogenous conditions in primary mouse T cells applying Alpha technology

scientific article published on 23 May 2019

Involvement of distinct PKC gene products in T cell functions ⬇️

scientific article published on August 6, 2012

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells

scientific article

Loss-of-function phenotype of a PKCθT219A knockin mouse strain

scientific article published on 06 November 2019

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

scientific article

Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4 T lymphocyte activation

scientific article published on 28 May 2019

Novel protein kinase C θ: coronin 1A complex in T lymphocytes

scientific article published on 31 March 2015

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.

scientific article

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo

scientific article published on 7 April 2009

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation

scientific article published on 12 August 2009

PKCtheta and PKA are antagonistic partners in the NF-AT transactivation pathway of primary mouse CD3+ T lymphocytes

scientific article published on 02 March 2006

PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes

scientific article (publication date: 2013)

Protein kinase C beta is dispensable for TCR-signaling

scientific article

Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.

scientific article published on 22 May 2017

Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells

scientific article (publication date: 2014)

Protein kinase Cepsilon is dispensable for TCR/CD3-signaling

scientific article published on 01 February 2005

Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice

scientific article published on 28 July 2016

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.

scientific article published on 2 June 2009

List of works by Nikolaus Thuille

Bactericidal activity of herbal extracts.

Comment on "PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation"

Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.

Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.

Defective IgG2a/2b class switching in PKC alpha-/- mice

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice

Development of a fast and sensitive method to study transcription factor activation under endogenous conditions in primary mouse T cells applying Alpha technology

Involvement of distinct PKC gene products in T cell functions ⬇️

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells

Loss-of-function phenotype of a PKCθT219A knockin mouse strain

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4 T lymphocyte activation

Novel protein kinase C θ: coronin 1A complex in T lymphocytes

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation

PKCtheta and PKA are antagonistic partners in the NF-AT transactivation pathway of primary mouse CD3+ T lymphocytes

PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes

Protein kinase C beta is dispensable for TCR-signaling

Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.

Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells

Protein kinase Cepsilon is dispensable for TCR/CD3-signaling

Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.