List of works - Rüdiger Wanke

A decade of experience with genetically tailored pig models for diabetes and metabolic research

scientific article published on 26 August 2020

Acaricide treatment prevents adrenocortical hyperplasia as a long-term stress reaction to psoroptic mange in cattle

scientific article

Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview

scientific article published on July 1991

Actions and interactions of growth hormone and insulin-like growth factor-II: body and organ growth of transgenic mice

scientific article published in May 1997

Attempts to localize the defect in dysgammaglobulinemia of UM-B19 chickens by studying the effect of immunomodulating substances on immunoglobulin and antibody production

scientific article published on 01 February 1987

Attenuation of cardiac hypertrophy by G-CSF is associated with enhanced migration of bone marrow-derived cells.

scientific article published on 8 March 2015

Betacellulin overexpression in transgenic mice causes disproportionate growth, pulmonary hemorrhage syndrome, and complex eye pathology

scientific article published on 22 September 2005

Betacellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro

scientific article

Betacellulin protects from pancreatitis by activating stress-activated protein kinase

scientific article published on 29 December 2009

Chicken egg antibodies for prophylaxis and therapy of infectious intestinal diseases. I. Immunization and antibody determination.

scientific article

Chronic tubulointerstitial nephropathy in six okapis (Okapia johnstoni)

scientific article published on 01 December 2001

Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research

scientific article published on 21 April 2016

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects

scientific article published on 04 December 2007

Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis

scientific article published on 11 February 2009

Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

scientific article

Diets influence the diabetic phenotype of transgenic mice expressing a dominant negative glucose-dependent insulinotropic polypeptide receptor (GIPRdn).

scientific article published on 23 October 2007

Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria

scientific article published on 29 April 2011

Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice

scientific article

Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe -Cell Loss in Munich Ins2C95S Mutant Mice

article by Nadja Herbach et al published 15 February 2007 in Diabetes

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

scientific article

Early insulin therapy prevents beta cell loss in a mouse model for permanent neonatal diabetes (Munich Ins2 C95S)

article

Effect of chronic GH overproduction on cardiac ANP expression and circulating ANP levels

scientific article published on 01 September 1998

Effects of IGFBP-2 overexpression in vitro and in vivo

scientific article (publication date: July 2000)

Effects of growth hormone overproduction on grip strength of transgenic mice

scientific article published in December 1995

Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models

article

Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition

scientific article

Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich Gck(D217V) mutants

scientific journal article

Erythropoietin administration after myocardial infarction in mice attenuates ischemic cardiomyopathy associated with enhanced homing of bone marrow-derived progenitor cells via the CXCR-4/SDF-1 axis.

scientific article

Exploration of global gene expression changes during the estrous cycle in equine endometrium.

scientific article published in June 2012

Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll.

scientific article published on 27 February 2007

Familial Nephropathy in Bernese Mountain Dogs

First inducible transgene expression in porcine large animal models

scientific article published on December 2011

Functional consequences of IGFBP excess-lessons from transgenic mice

scientific article

Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes

scientific article published on 26 October 2011

Genetic dissection of IGF1-dependent and -independent effects of permanent GH excess on postnatal growth and organ pathology of mice

scientific article published on 10 July 2014

Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function

scientific article published on 25 February 2010

Growth analysis of the mouse adrenal gland from weaning to adulthood: time- and gender-dependent alterations of cell size and number in the cortical compartment

scientific article

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. I. Body weight gain and external body dimensions

scientific article

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. II. Skeleton.

scientific article

Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth

scientific article published on March 2016

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

scientific article published in May 2001

HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity

scientific article

Identification of transgenic mice by direct PCR analysis of lysates of epithelial cells obtained from the inner surface of the rectum

scientific article published on 01 March 1998

Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets

scientific article

In vivo evidence for epidermal growth factor receptor (EGFR)-mediated release of prolactin from the pituitary gland

scientific article published on 13 September 2011

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

scientific article

Incretin actions and consequences of incretin-based therapies: lessons from complementary animal models

scientific article published on 12 October 2015

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells

scientific article published on 19 July 2012

Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/IGF-I excess on adrenocortical cells in vivo

scientific article

Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice.

scientific article published on April 2004

Integrin-linked kinase as a candidate downstream effector in proteinuria.

scientific article

Intestinal dimensions of mice divergently selected for body weight

scientific article

Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants

scientific article published on 20 April 2005

Location-specific expression of chemokines, TNF-α and S100 proteins in a teat explant model.

scientific article published on 17 August 2014

Longitudinal in vivo effects of growth hormone overexpression on bone in transgenic mice

scientific article

Microarray analysis of equine endometrium at days 8 and 12 of pregnancy

scientific article published on 14 July 2010

Natural killer (NK) activity of porcine blood lymphocytes against allogeneic melanoma target cells

scientific article published in August 1991

No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.

scientific article

Overexpression of a dominant negative GIP receptor in transgenic mice results in disturbed postnatal pancreatic islet and beta-cell development

scientific article published in February 2005

Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain

scientific article published in December 1999

Overgrowth of Skin in Growth Hormone Transgenic Mice Depends on the Presence of Male Gonads

article published in 1999

POLYCYSTIC KIDNEY DISEASE IN A EUROPEAN ROE DEER (CAPREOLUS CAPREOLUS)

scientific article published on 01 June 2013

Parathyroid hormone treatment after myocardial infarction promotes cardiac repair by enhanced neovascularization and cell survival

scientific article published on 30 November 2007

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

scientific article published on 28 December 2012

Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2).

scientific article published in December 2009

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

scientific article

Production of antibodies to canine distemper virus in chicken eggs for immunohistochemistry

scientific article

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

scientific article published on 27 April 2016

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

scientific article

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models

scientific journal article

Sensitive detection of human growth hormone mRNA in routinely formalin-fixed, paraffin-embedded transgenic mouse tissues by non-isotopic in situ hybridization

scientific article published on August 1994

Short-term inhibition of DPP-4 enhances endothelial regeneration after acute arterial injury via enhanced recruitment of circulating progenitor cells.

scientific article published on 22 September 2014

Specific transgene expression in mouse pancreatic beta-cells under the control of the porcine insulin promoter

scientific article published on 12 August 2009

Stereology--benefits and pitfalls

scientific article published on 01 August 2002

Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

scientific article

Systemic overexpression of growth hormone (GH) in transgenic FVB/N inbred mice: an optimized model for holistic studies of molecular mechanisms underlying GH-induced kidney pathology

article

The GH-transgenic mouse as an experimental model for growth research: clinical and pathological studies.

scientific article

The cardioprotective effects of parathyroid hormone are independent of endogenous granulocyte-colony stimulating factor release

scientific article published on 10 November 2011

The chicken egg, an antibody source.

scientific article

The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes

article by Birgit Rathkolb et al published July 2000 in Mammalian Genome

Tissue Sampling Guides for Porcine Biomedical Models.

scientific article published on 16 February 2016

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

scientific article published on 7 April 2004

Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice

scientific article published on 6 June 2013

Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice

scientific article published on 20 April 2012

[Antibody isotypes following immunization of truly dysgammaglobulinemic UM-B 19 hens]

scientific article published on 01 July 1982

[Freund's complete adjuvant in the chicken: efficient immunostimulation with severe local inflammatory reaction]

scientific article published on 01 June 1996

[Local reactions after the application of several adjuvants in the chicken]

scientific article published on 01 January 1996

[Occurrence and economic importance of congenital hernia in German Fleckvich calves]

scientific article published on 01 January 2001

[Occurrence of the arachnomelia syndrome in Bavarian Brown-Swiss x Braunvieh breed population]

scientific article published on 01 November 1984

[Role of podocyte damage in the pathogenesis of glomerulosclerosis and tubulointerstitial lesions: findings in the growth hormone transgenic mouse model of progressive nephropathy]

article

[Segregation of pigment cell anomalies in Munich miniature swine (MMS) Troll crossed with German Landrace]

scientific article published on 01 October 1995

List of works by Rüdiger Wanke

A decade of experience with genetically tailored pig models for diabetes and metabolic research

Acaricide treatment prevents adrenocortical hyperplasia as a long-term stress reaction to psoroptic mange in cattle

Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview

Actions and interactions of growth hormone and insulin-like growth factor-II: body and organ growth of transgenic mice

Attempts to localize the defect in dysgammaglobulinemia of UM-B19 chickens by studying the effect of immunomodulating substances on immunoglobulin and antibody production

Attenuation of cardiac hypertrophy by G-CSF is associated with enhanced migration of bone marrow-derived cells.

Betacellulin overexpression in transgenic mice causes disproportionate growth, pulmonary hemorrhage syndrome, and complex eye pathology

Betacellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro

Betacellulin protects from pancreatitis by activating stress-activated protein kinase

Chicken egg antibodies for prophylaxis and therapy of infectious intestinal diseases. I. Immunization and antibody determination.

Chronic tubulointerstitial nephropathy in six okapis (Okapia johnstoni)

Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects

Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis

Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

Diets influence the diabetic phenotype of transgenic mice expressing a dominant negative glucose-dependent insulinotropic polypeptide receptor (GIPRdn).

Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria

Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice

Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe -Cell Loss in Munich Ins2C95S Mutant Mice

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

Early insulin therapy prevents beta cell loss in a mouse model for permanent neonatal diabetes (Munich Ins2 C95S)

Effect of chronic GH overproduction on cardiac ANP expression and circulating ANP levels

Effects of IGFBP-2 overexpression in vitro and in vivo

Effects of growth hormone overproduction on grip strength of transgenic mice

Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models

Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition

Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich Gck(D217V) mutants

Erythropoietin administration after myocardial infarction in mice attenuates ischemic cardiomyopathy associated with enhanced homing of bone marrow-derived progenitor cells via the CXCR-4/SDF-1 axis.

Exploration of global gene expression changes during the estrous cycle in equine endometrium.

Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll.

Familial Nephropathy in Bernese Mountain Dogs

First inducible transgene expression in porcine large animal models

Functional consequences of IGFBP excess-lessons from transgenic mice

Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes

Genetic dissection of IGF1-dependent and -independent effects of permanent GH excess on postnatal growth and organ pathology of mice

Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function

Growth analysis of the mouse adrenal gland from weaning to adulthood: time- and gender-dependent alterations of cell size and number in the cortical compartment

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. I. Body weight gain and external body dimensions

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. II. Skeleton.

Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity

Identification of transgenic mice by direct PCR analysis of lysates of epithelial cells obtained from the inner surface of the rectum

Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets

In vivo evidence for epidermal growth factor receptor (EGFR)-mediated release of prolactin from the pituitary gland

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Incretin actions and consequences of incretin-based therapies: lessons from complementary animal models

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells

Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/IGF-I excess on adrenocortical cells in vivo

Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice.

Integrin-linked kinase as a candidate downstream effector in proteinuria.

Intestinal dimensions of mice divergently selected for body weight

Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants

Location-specific expression of chemokines, TNF-α and S100 proteins in a teat explant model.

Longitudinal in vivo effects of growth hormone overexpression on bone in transgenic mice

Microarray analysis of equine endometrium at days 8 and 12 of pregnancy

Natural killer (NK) activity of porcine blood lymphocytes against allogeneic melanoma target cells

No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.

Overexpression of a dominant negative GIP receptor in transgenic mice results in disturbed postnatal pancreatic islet and beta-cell development

Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain

Overgrowth of Skin in Growth Hormone Transgenic Mice Depends on the Presence of Male Gonads

POLYCYSTIC KIDNEY DISEASE IN A EUROPEAN ROE DEER (CAPREOLUS CAPREOLUS)

Parathyroid hormone treatment after myocardial infarction promotes cardiac repair by enhanced neovascularization and cell survival

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2).

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

Production of antibodies to canine distemper virus in chicken eggs for immunohistochemistry

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models

Sensitive detection of human growth hormone mRNA in routinely formalin-fixed, paraffin-embedded transgenic mouse tissues by non-isotopic in situ hybridization

Short-term inhibition of DPP-4 enhances endothelial regeneration after acute arterial injury via enhanced recruitment of circulating progenitor cells.

Specific transgene expression in mouse pancreatic beta-cells under the control of the porcine insulin promoter

Stereology--benefits and pitfalls

Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

Systemic overexpression of growth hormone (GH) in transgenic FVB/N inbred mice: an optimized model for holistic studies of molecular mechanisms underlying GH-induced kidney pathology

The GH-transgenic mouse as an experimental model for growth research: clinical and pathological studies.

The cardioprotective effects of parathyroid hormone are independent of endogenous granulocyte-colony stimulating factor release

The chicken egg, an antibody source.