List of works - Hsinyu Lee

A Gene Expression Profile for Vascular Invasion can Predict the Recurrence After Resection of Hepatocellular Carcinoma: a Microarray Approach

article

A Novel Function of the Lysophosphatidic Acid Receptor 3 (LPAR3) Gene in Zebrafish on Modulating Anxiety, Circadian Rhythm Locomotor Activity, and Short-Term Memory

scientific article published on 18 April 2020

A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

scientific article published on 12 July 2019

A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening.

scientific article

Allergic diathesis in transgenic mice with constitutive T cell expression of inducible vasoactive intestinal peptide receptor

scientific article published in November 2001

Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration.

scientific article published on 12 September 2017

Aromatic hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factor-A expression in PC-3 prostate cancer cells.

scientific article published on 3 July 2013

Aryl hydrocarbon receptor downregulates MYCN expression and promotes cell differentiation of neuroblastoma

scientific article

Autophagy: A double-edged sword in Alzheimer’s disease ⬇️

scientific article published on March 1, 2012

B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via β₁ integrin signaling in neuroblastoma

scientific article

Calreticulin Regulates VEGF-A in Neuroblastoma Cells

scientific article published on 7 October 2014

Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells

scientific article published on May 2014

Calreticulin mediates nerve growth factor-induced neuronal differentiation

scientific article

Changes in tumor growth and metastatic capacities of J82 human bladder cancer cells suppressed by down-regulation of calreticulin expression.

scientific article

Characterization of neuroblastic tumors using 18F-FDOPA PET.

scientific article published on 4 December 2012

Comparison of Immunomodulatory and Anticancer Activities in Different Strains of Tremella fuciformis Berk.

scientific article published on 30 November 2015

Connective tissue growth factor inhibits gastric cancer peritoneal metastasis by blocking integrin α3β1-dependent adhesion

scientific article

Corrigendum to “Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR” [FEBS Lett. 585 (2011) 3582-3586]

scholarly article published in FEBS Letters

Detection of circulating endothelial cells via a microfluidic disk

scientific article published on 4 February 2011

Dielectrophoresis-based cellular microarray chip for anticancer drug screening in perfusion microenvironments.

scientific article published on June 2011

Diurnal rhythm and effect of temperature on oxygen consumption in earthworms, Amynthas gracilis and Pontoscolex corethrurus

scientific article published on 01 September 2004

Epidermal growth factor up-regulates the expression of nestin through the Ras-Raf-ERK signaling axis in rat vascular smooth muscle cells

scientific article published on 11 October 2008

Establishment of a bioluminescence-based bioassay for the detection of dioxin-like compounds

scientific article published on 15 January 2013

Establishment of a cell-free bioassay for detecting dioxin-like compounds

scientific article published on 01 July 2013

Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells

scientific article published on 11 December 2013

Functional roles of calreticulin in cancer biology

scientific article published on 31 March 2015

GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors.

scientific article published in March 2005

Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis

scientific article published on October 2008

Identification of a rod domain-truncated isoform of nestin, Nes-SΔ₁₀₇₋₂₅₄, in rat dorsal root ganglia

scientific article published on 29 August 2013

Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer

scientific article

Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos

scientific article

Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2).

scientific article

Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression

scientific article published on 01 September 1998

Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with neuroblastoma

scientific article

Lysophosphatidic Acid and Hematopoiesis: From Microenvironmental Effects to Intracellular Signaling

scientific article published on 16 March 2020

Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells.

scientific article

Lysophosphatidic acid induces reactive oxygen species generation by activating protein kinase C in PC-3 human prostate cancer cells

scientific article published on 8 October 2013

Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta

scientific article published on 10 July 2008

Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.

scientific article published in October 2007

Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells.

scientific article published on 31 December 2007

Lysophosphatidic acid up-regulates expression of growth-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protein-1 in human first-trimester trophoblasts: possible roles in angiogenesis and immune regulation.

scientific article published on 11 November 2009

Lysophosphatidic acid up-regulates expression of interleukin-8 and -6 in granulosa-lutein cells through its receptors and nuclear factor-kappaB dependent pathways: implications for angiogenesis of corpus luteum and ovarian hyperstimulation syndrome.

scientific article published on 2 January 2008

Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages.

scientific article

Lysophospholipids elevate [Ca2+]i and trigger exocytosis in bovine chromaffin cells

scientific article published on 17 April 2006

Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells.

scientific article

Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism

scientific article published on 01 November 2006

MDA5 complements TLR3 in suppression of neuroblastoma

scientific article

MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells

scientific article published on 21 June 2013

Mechanisms of Lysophosphatidic Acid-Mediated Lymphangiogenesis in Prostate Cancer

scientific article published on 31 October 2018

Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics

scientific article published on 22 November 2013

Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma

scientific article published on 24 August 2010

Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma

scientific article

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

scientific article

Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells.

scientific article

Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation

scientific article published on 12 July 2019

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR.

scientific article published on 20 October 2011

Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn.

scientific article published on 18 April 2008

Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3

scientific article published on 20 February 2007

Sphingosine-1-phosphate in Endothelial Cell Recellularization Improves Patency and Endothelialization of Decellularized Vascular Grafts In Vivo ⬇️

scientific article published on 02 April 2019

Sphingosine-1-phosphate induces VEGF-C expression through a MMP-2/FGF-1/FGFR-1-dependent pathway in endothelial cells in vitro.

scientific article published on 04 February 2013

The Antithrombotic Function of Sphingosine-1-Phosphate on Human Adipose-Stem-Cell-Recellularized Tissue Engineered Vascular Graft In Vitro

scientific article published on 21 October 2019

The influence of biologic factors on the surgical decision in advanced neuroblastoma

scientific article published on 18 January 2006

The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos.

scientific article

Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array.

scientific article

Thrombin induces nestin expression via the transactivation of EGFR signalings in rat vascular smooth muscle cells

scientific article published on 24 February 2009

Toll-like receptor 3 expression inhibits cell invasion and migration and predicts a favorable prognosis in neuroblastoma.

scientific article published on 27 March 2013

Tyrosine sulphation of sphingosine 1-phosphate 1 (S1P1) is required for S1P-mediated cell migration in primary cultures of human umbilical vein endothelial cells

scientific article published on 19 August 2009

Unnatural amino acid-substituted (hydroxyethyl)urea peptidomimetics inhibit gamma-secretase and promote the neuronal differentiation of neuroblastoma cells.

scientific article published on 14 November 2006

VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma

scientific article

cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation

scientific article published in December 1997

β-1,4-Galactosyltransferase III enhances invasive phenotypes via β1-integrin and predicts poor prognosis in neuroblastoma

scientific article published on 26 February 2013

List of works by Hsinyu Lee

A Gene Expression Profile for Vascular Invasion can Predict the Recurrence After Resection of Hepatocellular Carcinoma: a Microarray Approach

A Novel Function of the Lysophosphatidic Acid Receptor 3 (LPAR3) Gene in Zebrafish on Modulating Anxiety, Circadian Rhythm Locomotor Activity, and Short-Term Memory

A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening.

Allergic diathesis in transgenic mice with constitutive T cell expression of inducible vasoactive intestinal peptide receptor

Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration.

Aromatic hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factor-A expression in PC-3 prostate cancer cells.

Aryl hydrocarbon receptor downregulates MYCN expression and promotes cell differentiation of neuroblastoma

Autophagy: A double-edged sword in Alzheimer’s disease ⬇️

B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via β₁ integrin signaling in neuroblastoma

Calreticulin Regulates VEGF-A in Neuroblastoma Cells

Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells

Calreticulin mediates nerve growth factor-induced neuronal differentiation

Changes in tumor growth and metastatic capacities of J82 human bladder cancer cells suppressed by down-regulation of calreticulin expression.

Characterization of neuroblastic tumors using 18F-FDOPA PET.

Comparison of Immunomodulatory and Anticancer Activities in Different Strains of Tremella fuciformis Berk.

Connective tissue growth factor inhibits gastric cancer peritoneal metastasis by blocking integrin α3β1-dependent adhesion

Corrigendum to “Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR” [FEBS Lett. 585 (2011) 3582-3586]

Detection of circulating endothelial cells via a microfluidic disk

Dielectrophoresis-based cellular microarray chip for anticancer drug screening in perfusion microenvironments.

Diurnal rhythm and effect of temperature on oxygen consumption in earthworms, Amynthas gracilis and Pontoscolex corethrurus

Epidermal growth factor up-regulates the expression of nestin through the Ras-Raf-ERK signaling axis in rat vascular smooth muscle cells

Establishment of a bioluminescence-based bioassay for the detection of dioxin-like compounds

Establishment of a cell-free bioassay for detecting dioxin-like compounds

Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells

Functional roles of calreticulin in cancer biology

GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors.

Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis

Identification of a rod domain-truncated isoform of nestin, Nes-SΔ₁₀₇₋₂₅₄, in rat dorsal root ganglia

Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer

Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos

Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2).

Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression

Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with neuroblastoma

Lysophosphatidic Acid and Hematopoiesis: From Microenvironmental Effects to Intracellular Signaling

Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells.

Lysophosphatidic acid induces reactive oxygen species generation by activating protein kinase C in PC-3 human prostate cancer cells

Lysophosphatidic acid mediates interleukin-8 expression in human endometrial stromal cells through its receptor and nuclear factor-kappaB-dependent pathway: a possible role in angiogenesis of endometrium and placenta

Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.

Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells.

Lysophosphatidic acid up-regulates expression of growth-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protein-1 in human first-trimester trophoblasts: possible roles in angiogenesis and immune regulation.

Lysophosphatidic acid up-regulates expression of interleukin-8 and -6 in granulosa-lutein cells through its receptors and nuclear factor-kappaB dependent pathways: implications for angiogenesis of corpus luteum and ovarian hyperstimulation syndrome.

Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages.

Lysophospholipids elevate [Ca2+]i and trigger exocytosis in bovine chromaffin cells

Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells.

Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism

MDA5 complements TLR3 in suppression of neuroblastoma

MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells

Mechanisms of Lysophosphatidic Acid-Mediated Lymphangiogenesis in Prostate Cancer

Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics

Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma

Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells.

Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR.

Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn.

Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3

Sphingosine-1-phosphate in Endothelial Cell Recellularization Improves Patency and Endothelialization of Decellularized Vascular Grafts In Vivo ⬇️

Sphingosine-1-phosphate induces VEGF-C expression through a MMP-2/FGF-1/FGFR-1-dependent pathway in endothelial cells in vitro.

The Antithrombotic Function of Sphingosine-1-Phosphate on Human Adipose-Stem-Cell-Recellularized Tissue Engineered Vascular Graft In Vitro

The influence of biologic factors on the surgical decision in advanced neuroblastoma

The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos.

Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array.

Thrombin induces nestin expression via the transactivation of EGFR signalings in rat vascular smooth muscle cells

Toll-like receptor 3 expression inhibits cell invasion and migration and predicts a favorable prognosis in neuroblastoma.

Tyrosine sulphation of sphingosine 1-phosphate 1 (S1P1) is required for S1P-mediated cell migration in primary cultures of human umbilical vein endothelial cells

Unnatural amino acid-substituted (hydroxyethyl)urea peptidomimetics inhibit gamma-secretase and promote the neuronal differentiation of neuroblastoma cells.

VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma

cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation

β-1,4-Galactosyltransferase III enhances invasive phenotypes via β1-integrin and predicts poor prognosis in neuroblastoma