List of works - Grazia Tamma

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

scientific article published on 18 December 2013

A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria.

scientific article

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency

scientific article

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

scientific journal article

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

scientific article

Activation of Calcium-Sensing Receptor increases intracellular calcium and decreases cAMP and mTOR in PKD1 deficient cells.

scientific article

Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease

scientific article published on 24 August 2018

Altered urinary excretion of aquaporin 2 in IgA nephropathy

scientific article published on 08 August 2011

An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells

scientific article published on 13 February 2001

Antioxidant Efficacy of Olive By-Product Extracts in Human Colon HCT8 Cells

scientific article published on 23 December 2020

Aquaporin Membrane Channels in Oxidative Stress, Cell Signaling, and Aging: Recent Advances and Research Trends.

scientific article published on 27 March 2018

Aquaporin-2 Excretion and Renal Function during the 1st Week of Life in Preterm Newborn Infants

Aquaporins as Targets of Dietary Bioactive Phytocompounds.

scientific article published on 18 April 2018

Aquaporins, vasopressin, and aging: current perspectives.

scientific article

Bradykinin signaling counteracts cAMP-elicited aquaporin 2 translocation in renal cells

scientific article published on 10 August 2005

CaSR signaling down-regulates AQP2 expression via a novel microRNA pathway in pendrin and NaCl cotransporter knockout mice.

scientific article published on 6 December 2017

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

scientific article

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

scientific article published on 22 December 2011

Co-Regulated Pendrin and Aquaporin 5 Expression and Trafficking in Type-B Intercalated Cells under Potassium Depletion

scientific article published on 18 December 2013

Comparison between men and women of volume regulating hormones and aquaporin-2 excretion following graded central hypovolemia

scientific article published on 18 December 2018

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

scientific article

Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of action

scientific article published on 05 January 2011

Effect of roscovitine on intracellular calcium dynamics: differential enantioselective responses.

scientific article published on 29 October 2013

Evaluating the Oxidative Stress in Renal Diseases: What Is the Role for S-Glutathionylation?

scientific article published on 14 March 2016

Excessive signal transduction of gain-of-function variants of the calcium-sensing receptor (CaSR) are associated with increased ER to cytosol calcium gradient

scientific article

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells.

scientific article published on December 2004

Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

scientific article published on 20 August 2011

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.

scientific article published on 4 April 2008

Glutathionylation of the aquaporin-2 water channel: a novel post-translational modification modulated by the oxidative stress

scientific article

Green olive leaf extract (OLE) provides cytoprotection in renal cells exposed to low doses of cadmium

scientific article published on 21 March 2019

Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling1 ⬇️

scientific article (publication date: 2 November 2001)

Hypotonicity Induces Aquaporin-2 Internalization and Cytosol-to-Membrane Translocation of ICln in Renal Cells

scientific article published on 30 November 2006

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

scientific article published on 01 April 2007

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

scientific journal article

Impact of atypical mitochondrial cyclic-AMP level in nephropathic cystinosis.

scientific article published on 16 March 2018

In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation

scientific article published on 24 March 2020

Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction

scientific article

Influence of bed rest on plasma galanin and adrenomedullin at presyncope.

scientific article published on 15 June 2015

Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.

scientific article published on 17 June 2011

Interleukin-13 increases pendrin abundance to the cell surface in bronchial NCI-H292 cells via Rho/actin signaling.

scientific article published on 4 April 2017

Minireview: aquaporin 2 trafficking.

scientific article

Mitochondrial cAMP prevents apoptosis modulating Sirt3 protein level and OPA1 processing in cardiac myoblast cells

scientific article published on 24 November 2016

Olive Leaf Extract (OLE) as a Novel Antioxidant That Ameliorates the Inflammatory Response in Cystic Fibrosis

scientific article published in July 2023

Olive Leaf Extract (OLE) as a Novel Antioxidant That Ameliorates the Inflammatory Response in Cystic Fibrosis

Oxidative Stress and Membrane Transport Systems

scientific article published on 13 June 2018

Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.

scientific article published on 19 August 2010

Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.

scientific article published on 9 December 2010

Regulation of aquaporin-2 trafficking.

scientific article published on January 2009

Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus

scientific article published in October 2009

Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells ⬇️

scientific article published on December 1, 2001

Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis.

scientific article published in October 2004

The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation

scientific article published on 29 May 2020

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

scientific article

Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells.

scientific article

Vasopressin-aquaporin-2 pathway: recent advances in understanding water balance disorders

scientific article published on 04 February 2019

Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

scientific article published on 24 April 2006

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.

scientific article published in April 2003

List of works by Grazia Tamma

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria.

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

Activation of Calcium-Sensing Receptor increases intracellular calcium and decreases cAMP and mTOR in PKD1 deficient cells.

Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease

Altered urinary excretion of aquaporin 2 in IgA nephropathy

An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells

Antioxidant Efficacy of Olive By-Product Extracts in Human Colon HCT8 Cells

Aquaporin Membrane Channels in Oxidative Stress, Cell Signaling, and Aging: Recent Advances and Research Trends.

Aquaporin-2 Excretion and Renal Function during the 1st Week of Life in Preterm Newborn Infants

Aquaporins as Targets of Dietary Bioactive Phytocompounds.

Aquaporins, vasopressin, and aging: current perspectives.

Bradykinin signaling counteracts cAMP-elicited aquaporin 2 translocation in renal cells

CaSR signaling down-regulates AQP2 expression via a novel microRNA pathway in pendrin and NaCl cotransporter knockout mice.

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

Co-Regulated Pendrin and Aquaporin 5 Expression and Trafficking in Type-B Intercalated Cells under Potassium Depletion

Comparison between men and women of volume regulating hormones and aquaporin-2 excretion following graded central hypovolemia

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of action

Effect of roscovitine on intracellular calcium dynamics: differential enantioselective responses.

Evaluating the Oxidative Stress in Renal Diseases: What Is the Role for S-Glutathionylation?

Excessive signal transduction of gain-of-function variants of the calcium-sensing receptor (CaSR) are associated with increased ER to cytosol calcium gradient

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells.

Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.

Glutathionylation of the aquaporin-2 water channel: a novel post-translational modification modulated by the oxidative stress

Green olive leaf extract (OLE) provides cytoprotection in renal cells exposed to low doses of cadmium

Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling1 ⬇️

Hypotonicity Induces Aquaporin-2 Internalization and Cytosol-to-Membrane Translocation of ICln in Renal Cells

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

Impact of atypical mitochondrial cyclic-AMP level in nephropathic cystinosis.

In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation

Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction

Influence of bed rest on plasma galanin and adrenomedullin at presyncope.

Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.

Interleukin-13 increases pendrin abundance to the cell surface in bronchial NCI-H292 cells via Rho/actin signaling.

Minireview: aquaporin 2 trafficking.

Mitochondrial cAMP prevents apoptosis modulating Sirt3 protein level and OPA1 processing in cardiac myoblast cells

Olive Leaf Extract (OLE) as a Novel Antioxidant That Ameliorates the Inflammatory Response in Cystic Fibrosis

Olive Leaf Extract (OLE) as a Novel Antioxidant That Ameliorates the Inflammatory Response in Cystic Fibrosis

Oxidative Stress and Membrane Transport Systems

Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.

Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.

Regulation of aquaporin-2 trafficking.

Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus

Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells ⬇️

Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis.

The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells.

Vasopressin-aquaporin-2 pathway: recent advances in understanding water balance disorders

Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.