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List of works by Mhairi Copland

A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells

scientific article published on 7 March 2014

A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease

scientific article published on 10 January 2020

Allogeneic stem cell transplantation for chronic myeloid leukaemia is safe and effective in high risk patients following second generation tyrosine kinase inhibitors: A single centre's experience

scientific article published on 03 July 2013

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

scientific article published on 16 September 2013

BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry.

scientific article published on June 2006

BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38- cells, through activation of protein kinase Cbeta.

scientific article published on 8 September 2009

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

scientific article published on 21 December 2007

CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy

scientific article published on 02 January 2020

Cancer stem cell definitions and terminology: the devil is in the details

scientific article published on 11 October 2012

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

scientific article published on 13 April 2011

Chronic myelogenous leukemia stem cells: What's new?

scientific article published on April 2009

Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation

scientific article published on 18 June 2012

Complete molecular responses are achieved after reduced intensity stem cell transplantation and donor lymphocyte infusion in chronic myeloid leukemia

scientific article published on 31 March 2008

Correction: CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy

scientific article published on 31 January 2020

DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML

scientific article published on 30 August 2014

Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

scientific article published on 9 February 2006

EZH2 in normal and malignant hematopoiesis

scientific article

Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells

scientific article published on December 2008

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia.

scientific article

Evolving molecular therapy for chronic myeloid leukaemia--are we on target?

scientific article

Fulminant tumour lysis syndrome in acute myelogenous leukaemia with inv(16)(p13;q22).

scientific article published in October 2002

Granulocyte--colony-stimulating factor (Filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase myelogenous leukemia

scientific article published in January 2005

Hedgehog signaling in cancer stem cells: a focus on hematological cancers.

scientific article

Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications.

scientific article published on 23 January 2013

Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia

scientific article published on 14 December 2016

How I manage priapism in chronic myeloid leukaemia patients.

scientific article

Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach

scientific article published on 15 February 2007

In a 12-allele analysis HLA-DPB1 matching is associated with improved OS in leukaemic and myelodysplastic patients receiving myeloablative T-cell-depleted PBSCT from unrelated donors

scientific article published on 17 February 2014

Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylate

scientific article published in January 2006

Intracellular protein trafficking kinetics in chronic myeloid leukemia stem cells using a microfluidic platform

scientific article published on 20 February 2012

Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells

scientific article published on 12 June 2009

Novel drug therapies in myeloid leukemia

scientific article published on January 2015

Oral anticoagulation and hemorrhagic complications in an elderly population with atrial fibrillation

scientific article published in September 2001

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

scientific article

Poor performance of galactomannan and mannan sandwich enzyme-linked immunosorbent assays in the diagnosis of invasive fungal infection

scientific article published in February 2005

Quantitative proteomics analysis of BMS-214662 effects on CD34 positive cells from chronic myeloid leukaemia patients.

scientific article

Targeting chronic myeloid leukemia stem cells.

scientific article published on March 2013

Targeting hedgehog in hematologic malignancy.

scientific article published on 05 January 2012

Targeting self-renewal pathways in myeloid malignancies ⬇️

scientific article published on May 15, 2013

Targeting the silent minority: emerging immunotherapeutic strategies for eradication of malignant stem cells in chronic myeloid leukaemia.

scientific article

The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells ⬇️

scientific article published on 12 April 2011

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors

scientific article

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

scientific article published on 06 January 2020

The role of the bone morphogenetic proteins in leukaemic stem cell persistence.

scientific article

The use of a risk group stratification in the management of invasive fungal infection: a prospective validation

scientific article published in February 2004

Tyrosine Kinase Inhibitor Independent Gene Expression Signature in CML Offers New Targets for LSPC Eradication Therapy

scientific article published on 26 October 2022

Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy

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