List of works - Roberta Ettari

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis

scientific article published on 17 January 2017

Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors

scientific article published on 10 June 2010

Design and synthesis of novel isoxazole-based HDAC inhibitors

scientific article published on 30 June 2010

Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes

scientific article published on 26 March 2019

Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).

scientific article

Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors

article

Development of novel selective peptidomimetics containing a boronic acid moiety, targeting the 20S proteasome as anticancer agents

scientific article

Development of peptidomimetic boronates as proteasome inhibitors

article

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors.

scientific article published on 31 January 2008

Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead

scientific article published on 15 November 2013

Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense

scientific article published on 13 June 2018

Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

scientific article published on 01 March 2014

Evaluation of curcumin irreversibility

scientific article published on 24 January 2019

Identification of a new series of amides as non-covalent proteasome inhibitors.

scientific article published on 25 January 2014

Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.

scientific article

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

scientific article published on 7 May 2013

Mechanism and site of inhibition of AMPA receptors: substitution of one and two methyl groups at the 4-aminophenyl ring of 2,3-benzodiazepine and implications in the "E" site.

scientific article published on 12 May 2015

Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives.

scientific article

Mechanism of falcipain-2 inhibition by α,β-unsaturated benzo[1,4]diazepin-2-one methyl ester

scientific article published on 11 September 2012

NMR characterization and conformational analysis of a potent papain-family cathepsin L-like cysteine protease inhibitor with different behaviour in polar and apolar media

article

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells

scientific article published on 01 December 2019

Nonpeptidic vinyl and allyl phosphonates as falcipain-2 inhibitors

scientific article published on July 2008

Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.

scientific article published on 12 August 2009

Novel Peptidomimetic Cysteine Protease Inhibitors as Potential Antimalarial Agents

scientific article published on 01 June 2006

Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

scientific article published on April 2009

Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis

scientific article published on 27 November 2019

Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors

scientific article

Peptide-based proteasome inhibitors in anticancer drug design.

scientific article published on March 2014

Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors

scientific article published on 03 March 2011

Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities

scientific article published on 11 August 2014

Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF‐CEM and Multidrug‐Resistant CEM/ADR5000 Leukemia Cells

scientific article published in 2021

Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

scientific article published on 16 April 2015

Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents

scientific article

Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.

scientific article

Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors

scientific article published on 25 January 2014

Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain

scientific article published on 14 April 2010

List of works by Roberta Ettari

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis

Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors

Design and synthesis of novel isoxazole-based HDAC inhibitors

Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes

Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).

Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors

Development of novel selective peptidomimetics containing a boronic acid moiety, targeting the 20S proteasome as anticancer agents

Development of peptidomimetic boronates as proteasome inhibitors

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors.

Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead

Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense

Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

Evaluation of curcumin irreversibility

Identification of a new series of amides as non-covalent proteasome inhibitors.

Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

Mechanism and site of inhibition of AMPA receptors: substitution of one and two methyl groups at the 4-aminophenyl ring of 2,3-benzodiazepine and implications in the "E" site.

Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives.

Mechanism of falcipain-2 inhibition by α,β-unsaturated benzo[1,4]diazepin-2-one methyl ester

NMR characterization and conformational analysis of a potent papain-family cathepsin L-like cysteine protease inhibitor with different behaviour in polar and apolar media

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells

Nonpeptidic vinyl and allyl phosphonates as falcipain-2 inhibitors

Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.

Novel Peptidomimetic Cysteine Protease Inhibitors as Potential Antimalarial Agents

Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis

Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors

Peptide-based proteasome inhibitors in anticancer drug design.

Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors

Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities

Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF‐CEM and Multidrug‐Resistant CEM/ADR5000 Leukemia Cells

Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents

Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.

Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors

Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain