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List of works by Frede Donskov

A five-factor biomarker profile obtained week 4-12 of treatment for improved prognostication in metastatic renal cell carcinoma: Results from DARENCA study 2.

scientific article

A population-based overview of sequences of targeted therapy in metastatic renal cell carcinoma.

scientific article published on 27 December 2013

A randomized phase II trial of interleukin-2 and interferon-α plus bevacizumab versus interleukin-2 and interferon-α in metastatic renal-cell carcinoma (mRCC): results from the Danish Renal Cancer Group (DaRenCa) study-1.

scientific article published on 2 February 2018

Active Smoking Is Associated With Worse Prognosis in Metastatic Renal Cell Carcinoma Patients Treated With Targeted Therapies

scientific article published on 12 September 2018

Adjuvant Sunitinib for High-risk Renal Cell Carcinoma After Nephrectomy: Subgroup Analyses and Updated Overall Survival Results.

scientific article published on 26 September 2017

Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy

scientific article

Adjuvant sunitinib in patients with high-risk renal cell carcinoma: safety, therapy management, and patient-reported outcomes in the S-TRAC trial

scientific article published on 01 October 2018

Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial

scientific article published on 09 May 2019

Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.

scientific article

Carbon anhydrase IX specific immune responses in patients with metastatic renal cell carcinoma potentially cured by interleukin-2 based immunotherapy.

scientific article

Carcinoma of Unknown Primary Site (CUP) With Metastatic Renal-Cell Carcinoma (mRCC) Histologic and Immunohistochemical Characteristics (CUP-mRCC): Results From Consecutive Patients Treated With Targeted Therapy and Review of Literature

scientific article published on 28 August 2018

Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy.

scientific article

Characteristics of long-term and short-term survivors of metastatic renal cell carcinoma treated with targeted therapies: results from the International mRCC Database Consortium

scientific article

Characterizing the impact of lymph node metastases on the survival outcome for metastatic renal cell carcinoma patients treated with targeted therapies.

scientific article published on 15 December 2014

Characterizing the outcomes of metastatic papillary renal cell carcinoma

scientific article published on 16 April 2017

CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma

scientific article published on 2 March 2017

Clinical Outcomes of First-line Sunitinib Followed by Immuno-oncology Checkpoint Inhibitors in Patients With Metastatic Renal Cell Carcinoma

scientific article published on 13 December 2019

Combination of zoledronic Acid and targeted therapy is active but may induce osteonecrosis of the jaw in patients with metastatic renal cell carcinoma

scientific article published in May 2013

Conditional survival of patients with metastatic renal-cell carcinoma treated with VEGF-targeted therapy: a population-based study.

scientific article published on 08 August 2012

Cytoreductive Nephrectomy in Metastatic Papillary Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium

scientific article published on 05 April 2019

Cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium.

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Diagnosis of hyponatremia and increased risk of a subsequent cancer diagnosis: results from a nationwide population-based cohort study

scientific article

Discontinuing VEGF-targeted Therapy for Progression Versus Toxicity Affects Outcomes of Second-line Therapies in Metastatic Renal Cell Carcinoma.

scientific article published on 12 January 2017

Dynamic Contrast-Enhanced Computed Tomography-Derived Blood Volume and Blood Flow Correlate With Patient Outcome in Metastatic Renal Cell Carcinoma

scientific article published on 01 February 2017

Dynamic contrast-enhanced computed tomography as a potential biomarker in patients with metastatic renal cell carcinoma: preliminary results from the Danish Renal Cancer Group Study-1.

scientific article published in September 2014

Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-Line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma

scientific article published on 01 September 2020

Efficacy of Second-line Targeted Therapy for Renal Cell Carcinoma According to Change from Baseline in International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Category

scientific article

Efficacy of targeted therapy for metastatic renal cell carcinoma in the elderly patient population.

scientific article

Elevated neutrophil-lymphocyte ratio combined with hyponatremia indicate poor prognosis in renal cell carcinoma

scientific article published on 26 August 2019

Everolimus-induced pneumonitis associates with favourable outcome in patients with metastatic renal cell carcinoma.

scientific article published on 3 June 2017

Expression and function of LFA-1 on A-NK and T-LAK cells: role in tumor target killing and migration into tumor tissue

scientific article published on 01 January 1996

External validation and comparison with other models of the International Metastatic Renal-Cell Carcinoma Database Consortium prognostic model: a population-based study

scientific article

Fas Ligand Expression in Metastatic Renal Cell Carcinoma During Interleukin-2 Based Immunotherapy: No In vivo Effect of Fas Ligand Tumor Counterattack

scientific article published on 01 December 2004

Favorable prognostic impact of Natural Killer cells and T cells in high-grade serous ovarian carcinoma

scientific article published on 14 January 2020

First-, second-, third-line therapy for mRCC: benchmarks for trial design from the IMDC.

scientific article published on April 2014

First-line Immuno-Oncology Combination Therapies in Metastatic Renal-cell Carcinoma: Results from the International Metastatic Renal-cell Carcinoma Database Consortium

scientific article published on 22 August 2019

First-line Mammalian target of rapamycin inhibition in metastatic renal cell carcinoma: an analysis of practice patterns from the International Metastatic Renal Cell Carcinoma Database Consortium

scientific article

First-line sunitinib versus pazopanib in metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium.

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Folic Acid Reduces Mucositis in Metastatic Renal Cell Carcinoma Patients: A Retrospective Study

scientific article published on 06 April 2019

Health economic changes as a result of implementation of targeted therapy for metastatic renal cell carcinoma: national results from DARENCA study 2.

scientific article published on December 2014

Hyponatremia as a prognostic and predictive factor in metastatic renal cell carcinoma.

scientific article

Hyponatremia associates with poor outcome in metastatic renal cell carcinoma patients treated with everolimus: prognostic impact

scientific article published on 04 June 2018

Immune response in blood and tumour tissue in patients with metastatic malignant melanoma treated with IL-2, IFN alpha and histamine dihydrochloride.

scientific article published in January 2003

Immunohistochemical expression of carbonic anhydrase IX assessed over time and during treatment in renal cell carcinoma

scientific article published on 01 June 2008

Immunomonitoring and prognostic relevance of neutrophils in clinical trials.

scientific article published on 10 February 2013

Impact of baseline and nadir neutrophil index in non-small cell lung cancer and ovarian cancer patients: Assessment of chemotherapy for resolution of unfavourable neutrophilia.

scientific article published on 15 August 2013

Impact of bone and liver metastases on patients with renal cell carcinoma treated with targeted therapy

scientific article

Impact of immune parameters on long-term survival in metastatic renal cell carcinoma

scientific article published in May 2006

Improved overall survival after implementation of targeted therapy for patients with metastatic renal cell carcinoma: results from the Danish Renal Cancer Group (DARENCA) study-2.

scientific article published on 8 November 2013

Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma

scientific article published on 01 February 2009

Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma.

scientific article published on 22 September 2011

Leukocyte orchestration in blood and tumour tissue following interleukin-2 based immunotherapy in metastatic renal cell carcinoma.

scientific article published on 15 April 2004

Living with Advanced Kidney Cancer and Treatment with Cabozantinib: Through the Eyes of the Patient and the Physician

scientific article published on 22 March 2018

Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma--results from a randomised phase II trial

scientific article published on January 2006

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

scientific article published on 21 March 2018

Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial

scientific article published on 16 August 2019

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

scientific article published on 25 September 2015

On-treatment biomarkers in metastatic renal cell carcinoma: towards individualization of prognosis?

scientific article

Outcome of patients with metastatic sarcomatoid renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium.

scientific article published on 23 September 2014

Outcomes based on age in the phase III METEOR trial of cabozantinib versus everolimus in patients with advanced renal cell carcinoma

scientific article published on 27 December 2019

Outcomes of patients with metastatic renal cell carcinoma that do not meet eligibility criteria for clinical trials.

scientific article

Outpatient treatment with subcutaneous histamine dihydrochloride in combination with interleukin-2 and interferon-alpha in patients with metastatic renal cell carcinoma: results of an open single-armed multicentre phase II study

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Pazopanib Exposure Relationship with Clinical Efficacy and Safety in the Adjuvant Treatment of Advanced Renal Cell Carcinoma.

scientific article published on 12 January 2018

Pazopanib-Induced Liver Toxicity in Patients With Metastatic Renal Cell Carcinoma: Effect of UGT1A1 Polymorphism on Pazopanib Dose Reduction, Safety, and Patient Outcomes

scientific article published on 26 September 2019

Phase III Trial of Adjuvant Sunitinib in Patients With High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis

scientific article published on 06 November 2018

Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma

scientific article published on 31 August 2009

Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy

scientific article

Progression-free survival as a predictor of overall survival in metastatic renal cell carcinoma treated with contemporary targeted therapy.

scientific article

Quality of Life Outcomes for Cabozantinib Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma: METEOR Phase III Randomized Trial.

scientific article published on 29 January 2018

Randomized Phase III Trial of Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma.

scientific article published on 13 September 2017

Real-World Assessment of Clinical Outcomes Among First-Line Sunitinib Patients with Clear Cell Metastatic Renal Cell Carcinoma (mRCC) by the International mRCC Database Consortium Risk Group

scientific article published on 23 January 2020

Real-world outcomes of nivolumab and cabozantinib in metastatic renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium

scientific article published on 01 April 2019

Registrations of Patients with Renal Cell Carcinoma in the Nationwide Danish Renal Cancer Database versus the Danish Cancer Registry: Data Quality, Completeness and Survival (DaRenCa Study-3)

scientific article published on 27 July 2020

Sunitinib-associated hypertension and neutropenia as efficacy biomarkers in metastatic renal cell carcinoma patients

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Sunitinib-induced hypertension, neutropaenia and thrombocytopaenia as predictors of good prognosis in patients with metastatic renal cell carcinoma

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Survival outcome and treatment response of patients with late relapse from renal cell carcinoma in the era of targeted therapy.

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Synchronous Versus Metachronous Metastatic Disease: Impact of Time to Metastasis on Patient Outcome-Results from the International Metastatic Renal Cell Carcinoma Database Consortium

scientific article published on 06 February 2020

The Advent of Psycho-oncology in Metastatic Renal Cell Carcinoma

scientific article published on 07 June 2016

The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study

scientific article published on 12 February 2015

The database of the Danish Renal Cancer Group

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The impact of low serum sodium on treatment outcome of targeted therapy in metastatic renal cell carcinoma: results from the International Metastatic Renal Cell Cancer Database Consortium

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Third-line Targeted Therapy in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium.

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Treatment Beyond Progression in Patients with Advanced Renal Cell Carcinoma Treated with Nivolumab in CheckMate 025.

scientific article published on 12 April 2017

Tumor-associated neutrophils and macrophages in non-small cell lung cancer: no immediate impact on patient outcome.

scientific article published on 26 March 2013

Tumor-associated neutrophils as a new prognostic factor in cancer: a systematic review and meta-analysis

scientific article

Tumour-associated CD66b+ neutrophil count is an independent prognostic factor for recurrence in localised cervical cancer

scientific article published on 16 April 2013

Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients.

scientific article published on 16 November 2017

[Medical work when cancer is organized as an acute disease. New South Wales, Australia, an example]

scientific article published on 01 December 2007

[Nephrectomy in metastatic renal cell carcinoma--an old myth in new clothes?]

scientific article published on 01 February 2003