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List of works by Moustapha Hassan

A pharmacodynamic study of 5-azacytidine in the P39 cell line

scientific article published on January 2006

Activation of Wnt/β-catenin pathway in monocytes derived from chronic kidney disease patients

scientific article published on 23 July 2013

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain

scientific article published on 8 June 2008

Alteration of interleukin 2 (IL-2) pharmacokinetics and function by IL-2 antibodies induced after treatment of colorectal carcinoma patients with a combination of monoclonal antibody 17-1A, granulocyte macrophage colony-stimulating factor, and IL-2

scientific article published on 01 May 2001

Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin.

scientific article published in February 2003

Analysis of roscovitine using novel high performance liquid chromatography and UV-detection method: pharmacokinetics of roscovitine in rat.

scientific article published in February 2004

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

scientific article published on 13 October 2016

Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice.

scientific article published in August 2005

Binding of busulfan to plasma proteins and blood cells ⬇️

scientific article published on 01 October 1984

Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes

scientific article published on 9 April 2003

Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging

scientific article published in April 2014

Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging

scientific article published on 19 December 2016

Biodistribution of liposomal 131I-VIP in rat using gamma camera

scientific article published on 01 November 1999

Biodistribution, kinetics, and biological fate of SPION microbubbles in the rat.

scientific article

Bone and hormonal status 10 years post-allogeneic bone marrow transplantation

scientific article published on 12 November 2019

Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis

scientific article

Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants

scientific article published on 01 June 1995

Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders

scientific article published on 01 November 1996

Busulphan-cyclophosphamide cause endothelial injury, remodeling of resistance arteries and enhanced expression of endothelial nitric oxide synthase

scientific article (publication date: 2012)

CT Scanning and MATLAB Calculations for Preservation of Coptic Mural Paintings in Historic Egyptian Monasteries

scientific article published on 07 March 2019

Circadian variability of bilirubin in healthy men during normal sleep and after an acute shift of sleep

scientific article published in December 2009

Cold isostatic pressing of hydrating calcium sulfate as a means to produce parenteral slow-release drug formulations

Commentary: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus

scientific article published on 19 February 2016

Comparison of algorithms for oral busulphan area under the concentration-time curve limited sampling estimate

scientific article published in January 2014

Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid

scientific article published on 06 August 2014

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

scientific article

Cyclophosphamide Pharmacokinetics in Mice: A Comparison Between Retro Orbital Sampling Versus Serial Tail Vein Bleeding

Cyclophosphamide alters the gene expression profile in patients treated with high doses prior to stem cell transplantation.

scientific article published on 22 January 2014

Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies

scientific article published on 20 January 2015

DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line.

scientific article published on 27 May 2015

DYNAMIC MR IMAGING, BIODISTRIBUTION AND PHARMACOKINETICS OF POLYMER SHELLED MICROBUBBLES CONTAINING SPION

Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4

scientific article published on 01 June 2019

Development and biodistribution of a theranostic aluminum phthalocyanine nanophotosensitizer

scientific article published on 18 December 2015

Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation

scientific article

Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions

scientific article published on 4 May 2017

Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice

scientific article published on 12 April 2017

Downregulation of miR-1266-5P, miR-185-5P and miR-30c-2 in prostatic cancer tissue and cell lines.

scientific article

Dynamics of fat cell turnover in humans

scientific article (publication date: 5 June 2008)

Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?

scientific article published on 23 July 2012

Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice

scientific article published in March 2005

Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line

scientific article published on August 2002

Endometrial endothelial cells are derived from donor stem cells in a bone marrow transplant recipient.

scientific article published on 2 November 2007

Evaluation of Immune Responses to Seasonal Influenza Vaccination in Healthy Volunteers and in Patients After Stem Cell Transplantation

article

Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning

scientific article

Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice

article

Fetal Mesenchymal Stem-Cell Engraftment in Bone after In Utero Transplantation in a Patient with Severe Osteogenesis Imperfecta

article

Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.

scientific article published on 9 November 2017

Fluorescence labeled microbubbles for multimodal imaging.

scientific article published on 14 July 2015

G-CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield.

scientific article published on 19 January 2017

Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine

scientific article

Hematologic malignancies in elderly patients

scientific article

High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients

scientific article published on 01 December 1997

Higher plasma but not intracellular concentrations after infusion with liposomal daunorubicin compared with conventional daunorubicin in adult acute myeloid leukemia

scientific article published in October 2007

Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells

scientific article

Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response.

scientific article published on July 2003

Immunotoxicological effects of streptozotocin and alloxan: in vitro and in vivo studies

scientific article

Importance of the surface chemistry of nanoparticles on peroxidase-like activity

scientific article published on 4 July 2017

In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.

scientific article

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

scientific article

Increased risk of gastrointestinal acute GVHD following the addition of melphalan to busulfan/cyclophosphamide conditioning

article

Infection-associated hemophagocytic syndrome complicated by infectious lymphoproliferation: a case report.

scientific article published on March 1996

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

scientific article

Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients

scientific article published in February 2006

Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy

scientific article published on 01 August 2000

Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver

scientific article published on 01 July 1995

Liposomal busulphan: bioavailability and effect on bone marrow in mice

scientific article published on 01 November 1998

Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib

scientific article published in August 2009

Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI.

scientific article published in July 2011

Lung Epithelial Cells and Type II Pneumocytes of Donor Origin After Allogeneic Hematopoietic Stem Cell Transplantation

scientific article published on 01 July 2004

Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies

scientific article published on 11 January 2018

Multimodal Imaging of Pancreatic Ductal Adenocarcinoma Using Multifunctional Nanoparticles as Contrast Agents

scientific article published on 17 November 2020

Multimodality imaging using SPECT/CT and MRI and ligand functionalized 99mTc-labeled magnetic microbubbles.

scientific article

Myeloablative and immunosuppressive properties of treosulfan in mice

scientific article published on January 2006

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

scientific article

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro

scientific article published on 21 February 2011

Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion

scientific article published on 26 November 2012

One Year on Tacrine (THA): Clinical and Biochemical Effects in Patients With Dementia of the Alzheimer Type ⬇️

scientific article published on January 1, 1995

Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee

scientific article

Pharmacogenetics of cyclophosphamide in patients with hematological malignancies

scientific article published on 23 September 2005

Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method

scientific article published on 16 November 2019

Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice

scientific article

Posaconazole concentrations in human tissues after allogeneic stem cell transplantation

scientific article published on 2 June 2014

Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization

scientific article published on 22 June 2017

Rat islets are not rejected by anti-islet antibodies in mice treated with costimulation blockade

scientific article published on 8 May 2014

Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound.

scientific article

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

scientific article published on 23 October 2013

Role of pharmacogenetics in busulfan/cyclophosphamide conditioning therapy prior to hematopoietic stem cell transplantation

scientific article published on January 2013

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation

SERS Quantification and Characterization of Proteins and Other Biomolecules.

scientific article

Safe administration of oral BU twice daily during conditioning for stem cell transplantation in a paediatric population: a comparative study between the standard 4-dose and a 2-dose regimen.

scientific article

Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression

scientific article published on 29 May 2018

Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma

scientific article published in June 2002

Somatostatin in neuroblastoma and ganglioneuroma

scientific article published on 01 October 1997

Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis

scientific article published on March 2013

Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice

scientific article published on 28 August 2016

Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats

scientific article published on 23 March 2019

The Effect of Repeated Administration of Cyclophosphamide on Cytochrome P450 2B in Rats

scientific article published on 01 July 2007

The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity

The effect of ciprofloxacin on cyclophosphamide pharmacokinetics in patients with non-Hodgkin lymphoma

scientific article published in September 2005

The effect of circadian rhythm on pharmacokinetics and metabolism of the Cdk inhibitor, roscovitine, in tumor mice model.

scientific article

The influence of interferon-alpha on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite in patients with multiple myeloma

scientific article published on 01 September 1999

The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells.

scientific article published on 2 December 2013

The role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host disease

scientific article

The somatostatin analogue octreotide inhibits neuroblastoma growth in vivo

scientific article published on 01 September 1999

The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo

scientific article published in January 2001

Therapeutic drug monitoring is essential for intravenous busulfan therapy in pediatric hematopoietic stem cell recipients

scientific article published on 08 July 2011

Thermostable luciferase from Luciola cruciate for imaging of carbon nanotubes and carbon nanotubes carrying doxorubicin using in vivo imaging system

scientific article published on 25 March 2013

Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat.

scientific article published in May 2005

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.

scientific article published on 14 July 2015

Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study

scientific article published on 21 October 2020

miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines

scientific article published on 24 August 2018

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