List of works by Karel Holada

A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity

scientific article published on 01 January 1998

Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein

scientific article published on 01 July 2002

An effective "three-in-one" screening assay for testing drug and nanoparticle toxicity in human endothelial cells

scientific article published in PLoS ONE

Binding of prion antibodies to white blood cells of nonhuman primates and the existence of washable pool of cellular prion protein associated with lymphocytes in peripheral blood

scientific article published on 01 September 2010

Blood storage affects the detection of cellular prion protein on peripheral blood leukocytes and circulating dendritic cells in part by promoting platelet satellitism

scientific article published on 13 April 2012

CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc).

scientific article

Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors

scientific article published in September 2009

Carbon nanotubes activate store-operated calcium entry in human blood platelets

scientific article published on 08 June 2011

Cellular prion protein in blood platelets associates with both lipid rafts and the cytoskeleton

scientific article published on 01 November 2009

Cellular prion protein is expressed on endothelial cells and is released during apoptosis on membrane microparticles found in human plasma

scientific article published in March 2002

Changes in cellular prion protein expression, processing and localisation during differentiation of the neuronal cell line CAD 5

scientific article published on 06 December 2019

Comparison of rat and human major platelet glycoproteins

scientific article published on 01 January 1991

Deletion of protease-activated receptor 2 prolongs survival of scrapie-inoculated mice

scientific article published on 13 June 2012

Detection of the GPI-anchorless prion protein fragment PrP226* in human brain.

scientific article

Development of monoclonal antibodies specific for glycated prion protein.

scientific article

Different levels of prion protein (PrPc) expression on hamster, mouse and human blood cells

scientific article published on 01 August 2000

Divergent expression of cellular prion protein on blood cells of human and nonhuman primates

scientific article published on 21 August 2007

Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria

scientific article published on 01 June 2004

Endothelial desquamating activity of rat synthetic fibrinopeptide B and its analogues "in vivo": identification of responsible sequence

scientific article published in May 1994

Expression of cellular prion protein on blood cells: potential functions in cell physiology and pathophysiology of transmissible spongiform encephalopathy diseases.

scientific article

Expression of the cellular prion protein affects posttransfusion recovery and survival of red blood cells in mice

scientific article published on 30 May 2015

Gerstmann-Sträussler-Scheinker syndrome with the P102L pathogenic mutation presenting as familial Creutzfeldt-Jakob disease: a case report and review of the literature.

scientific article

Increased expression of phosphatidylinositol-specific phospholipase C resistant prion proteins on the surface of activated platelets.

scientific article

Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen

scientific article published on 02 May 2019

Photodynamic effects of meso-tetra (4-sulfonatophenyl)porphine on human leukemia cells HEL and HL60, human lymphocytes and bone marrow progenitor cells

scientific article published on 01 July 1997

Photodynamic inactivation of prions by disulfonated hydroxyaluminium phthalocyanine.

scientific article

Platelet membrane receptors during short cardiopulmonary bypass--a flow cytometric study

scientific article published on 01 September 1996

Precision in the design of an experimental study deflects the significance of proteinase-activated receptor 2 expression in scrapie-inoculated mice.

scientific article published on 14 June 2017

Production, purification and oxidative folding of the mouse recombinant prion protein

scientific article published in January 2007

Quinacrine reactivity with prion proteins and prion-derived peptides

scientific article published on 23 January 2013

Reactivity of 9-aminoacridine drug quinacrine with glutathione limits its antiprion activity.

scientific article published on 9 December 2016

Reduced erythroid cell and erythropoietin production in response to acute anemia in prion protein-deficient (Prnp-/-) mice

scientific article published on 26 October 2007

Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin

scientific article

Scrapie infectivity in hamster blood is not associated with platelets.

scientific article

The effect of protein corona composition on the interaction of carbon nanotubes with human blood platelets

scientific article published on 13 May 2014

Toxicity of carboxylated carbon nanotubes in endothelial cells is attenuated by stimulation of the autophagic flux with the release of nanomaterial in autophagic vesicles.

scientific article published on 22 February 2014

Transmission of BSE by blood transfusion

Underestimation of the expression of cellular prion protein on human red blood cells

scientific article published on 8 November 2010

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