Search filters

List of works by Jordi Heijman

Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses

scientific article published on 22 July 2020

Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac Arrhythmias ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

scientific article published on 30 July 2020

Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia--is there a mechanistic link between sarcoplasmic reticulum Ca(2+) leak and re-entry?

scientific article

Bayesian network analyses in atrial fibrillation - A path to better therapies?

Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin

scientific article published on 22 October 2020

Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics: How Close to Clinical Implementation?

scientific article published on 27 March 2015

Calcium dysregulation in atrial fibrillation: the role of CaMKII

scientific article

Calcium handling and atrial fibrillation.

scientific article published on July 2012

Cardiac safety assays

scientific article

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies

scientific article published on 15 March 2020

Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression

scientific article published on April 2014

Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation.

scientific article

Challenges to the translation of basic science findings to atrial fibrillation therapies

scientific article published on 19 April 2016

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity

scientific article

Computational modeling: What does it tell us about atrial fibrillation therapy?

scientific article published on 25 January 2019

Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation.

scientific article

Computational models of atrial fibrillation: achievements, challenges, and perspectives for improving clinical care

scientific article

Constitutive activity of the acetylcholine-activated potassium current IK,ACh in cardiomyocytes.

scientific article

Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysis

scientific article (publication date: 2013)

Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation.

scientific article

Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

scientific article published on May 2016

Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1.

scientific article

Electrical storm: recent pathophysiological insights and therapeutic consequences.

scientific article published on 21 February 2013

Electrocardiographic characteristics associated with atrial fibrillation - What do they tell us?

scientific article published on 01 September 2018

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

scientific article

Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci

scientific article published on 08 July 2019

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management

article

Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction

scientific article published on 20 November 2019

I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.

scientific article published on 8 September 2009

Impaired Na⁺-dependent regulation of acetylcholine-activated inward-rectifier K⁺ current modulates action potential rate dependence in patients with chronic atrial fibrillation.

scientific article published on 24 March 2013

Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology

scientific article published in 2022

Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

scientific article published in October 2017

Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation

scientific article published on 30 December 2020

Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy

scientific article published on 4 January 2017

Investigational antiarrhythmic agents: promising drugs in early clinical development.

scientific article

Ion channels as part of macromolecular multiprotein complexes : Clinical significance

scientific article published on 6 December 2017

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

scientific article published on 28 May 2015

KCNQ1 autoantibodies: another way to regulate IKs.

scientific article

Left atrial activation and asymmetric anatomical remodeling in patients with atrial fibrillation: The relation between anatomy and function

scientific article published on 17 November 2020

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient ⬇️

scientific article published on February 21, 2011

Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation

scientific article published on 18 August 2014

Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs

scientific article published on 04 September 2019

Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy: A Translational Perspective

scientific article published on 18 June 2020

Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation

scientific article published on 22 December 2017

New antiarrhythmic targets in atrial fibrillation

scientific article

New directions in antiarrhythmic drug therapy for atrial fibrillation

scientific article published on January 2013

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

scientific article published on 07 December 2016

Pleiotropic actions of amiodarone: still puzzling after half a century

scientific article published on 9 April 2013

Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation

scientific article published on 11 August 2013

Postoperative atrial fibrillation: mechanisms, manifestations and management

scientific article published on 01 July 2019

Potassium channels in the heart: structure, function and regulation.

scientific article published on 13 November 2016

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

scientific article published on 3 November 2016

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

article by Cristina E Molina et al published 2018 in Frontiers in Physiology

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

scientific article published on 23 January 2009

Rat engineered heart tissue: a novel tool in the safety pharmacology toolkit?

scientific article published on 11 September 2014

Recurrence of atrial fibrillation following non-cardiac surgery or acute illness: A common but rarely detected complication

scientific article published on 06 August 2020

Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update

scientific article published on 16 October 2017

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"

scientific article published on 01 March 2016

Resveratrol: an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?

scientific article published on 20 September 2018

Rhythm control of atrial fibrillation in heart failure.

scientific article

Serine/Threonine Phosphatases in Atrial Fibrillation

scientific article published on 7 January 2017

Stretching the limits of antiarrhythmic drug therapy: The promise of small-conductance calcium-activated potassium channel blockers

scientific article

Systems approaches to post-operative atrial fibrillation - do they help us to better understand the ionic basis of the arrhythmogenic substrate?

scientific article published on 21 June 2012

T-wave Right Slope Provides a New Angle in the Prediction of Drug-Induced Ventricular Arrhythmias : Editorial to: "Electrocardiographic Predictors of Torsadogenic Risk During Dofetilide or Sotalol Initiation: Utility of a Novel T Wave Analysis Progr

scientific article published on 01 October 2015

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?

scientific article published on 01 October 2017

The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling

scientific article published on 29 January 2016

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

scientific article published on 23 December 2015

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction

scientific article published on 04 June 2015

Translational Challenges in Atrial Fibrillation.

scientific article

Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation.

scientific article published on 7 May 2015

Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it ⬇️

journal article from 'Cardiovascular Research' published in 2021

[Cardiovascular pharmacotherapy. Risks and adverse effects]

scientific article published on 01 March 2014

Paulina is supported by:

About Paulina

Help