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List of works by Sophie Lucas

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma

scientific article

Activation of latent transforming growth factor-β1, a conserved function for pregnancy-specific beta 1-glycoproteins

scientific article published on 01 December 2018

Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects.

scientific article published on 12 April 2017

Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8.

scientific article published on 6 November 2017

Circulating Follicular Regulatory T Cells Are Defective in Multiple Sclerosis.

scientific article published on 12 June 2015

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

scientific article published in Scientific Reports

Comparison of stable human Treg and Th clones by transcriptional profiling.

scientific article published in March 2009

Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA.

scientific article published on 12 June 2017

Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen.

scientific article

Demethylation of the FOXP3 gene in human melanoma cells precludes the use of this epigenetic mark for quantification of Tregs in unseparated melanoma samples.

scientific article published on 2 August 2011

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

scientific article published on 21 December 2010

Functions of Anti-MAGE T-Cells Induced in Melanoma Patients under Different Vaccination Modalities

scientific article published on 01 May 2008

GARP is regulated by miRNAs and controls latent TGF-β1 production by human regulatory T cells

scientific article

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

scientific article

Identification of human testis-specific transcripts and analysis of their expression in tumor cells

scientific article published in December 1997

Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815

scientific article published on 01 March 1995

Infusion of clinical-grade enriched regulatory T cells delays experimental xenogeneic graft-versus-host disease.

scientific article published on 17 June 2013

LAGE-1, a new gene with tumor specificity

scientific article

Leukemia inhibitory factor tips the immune balance towards regulatory T cells in multiple sclerosis.

scientific article published on 13 December 2014

Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells.

scientific article published on 30 June 2015

Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg

scientific article published in December 2009

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.

scientific article

Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma

scientific article

Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis

scientific article published on 25 August 2011

Regulatory T cells control toxicity in a humanized model of IL-2 therapy

scientific article published on 24 November 2017

Role of GARP in the activation of latent TGF-β1.

scientific article published on 10 August 2017

Route of Administration Modulates the Induction of Dendritic Cell Vaccine-Induced Antigen-Specific T Cells in Advanced Melanoma Patients

scientific article published on 19 July 2011

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

scientific article published on 11 September 2020

Structural basis of latent TGF-β1 presentation and activation by GARP on human regulatory T cells

scientific article

Targeting immunosuppression by Tregs with monoclonal antibodies against GARP

scientific article

The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.

scientific article