List of works by John L. Rubinstein

A Bayesian method for 3D macromolecular structure inference using class average images from single particle electron microscopy.

scientific article

A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery

scientific article published on 09 January 2020

ATP synthase from Saccharomyces cerevisiae: location of subunit h in the peripheral stalk region.

scientific article published in January 2005

ATP synthase from Saccharomyces cerevisiae: location of the OSCP subunit in the peripheral stalk region

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Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference

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Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase

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Alignment of cryo-EM movies of individual particles by optimization of image translations.

scientific article published on 18 August 2015

Angle determination for side views in single particle electron microscopy

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Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM.

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Assembly and structural analysis of a covalently closed nano-scale DNA cage.

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Atomic model for the dimeric FO region of mitochondrial ATP synthase.

scientific article published on 26 October 2017

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

scientific article published on 24 October 2016

Automated particle picking for low-contrast macromolecules in cryo-electron microscopy

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Cryo-EM Captures the Dynamics of Ion Channel Opening.

scientific article published on January 2017

Cryo-EM structure of the yeast ATP synthase.

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Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases

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Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images

scientific article published on 15 June 2015

Edged watershed segmentation: a semi-interactive algorithm for segmentation of low-resolution maps from electron cryomicroscopy.

scientific article published on 6 July 2011

Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase

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Electron cryomicroscopy of membrane proteins: specimen preparation for two-dimensional crystals and single particles.

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Electron-event representation data enable efficient cryoEM file storage with full preservation of spatial and temporal resolution

scientific article published on 07 August 2020

Enzyme mechanisms: Flexibility leads to function

scientific article published on 01 March 2014

Eukaryotic V-ATPase: novel structural findings and functional insights

scientific article published on 04 February 2014

Fabrication of carbon films with ∼ 500nm holes for cryo-EM with a direct detector device.

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Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

scientific article published on 01 October 2019

Location of subunit d in the peripheral stalk of the ATP synthase from Saccharomyces cerevisiae.

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Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance

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Multiple conformations facilitate PilT function in the type IV pilus

scientific article published on 15 November 2019

Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

scientific article published on 16 June 2021

Phospholipid association is essential for dynamin-related protein Mgm1 to function in mitochondrial membrane fusion.

scientific article published on 24 August 2009

Radiation damage in electron cryomicroscopy.

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Shake-it-off: a simple ultrasonic cryo-EM specimen-preparation device

scientific article published on 22 November 2019

Structural Insights into KCTD Protein Assembly and Cullin3 Recognition

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Structural analysis of membrane protein complexes by single particle electron microscopy.

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Structural biology. Beyond blob-ology

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Structural ordering of the <i>Plasmodium berghei</i> circumsporozoite protein repeats by inhibitory antibody 3D11

scientific article published on 30 November 2020

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.

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Structure of V-ATPase from the mammalian brain

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Structure of a AAA+ unfoldase in the process of unfolding substrate.

scientific article published on 8 April 2017

Structure of a bacterial ATP synthase

scientific article published on 06 February 2019

Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis

scientific article published on 05 December 2018

Structure of intact Thermus thermophilus V-ATPase by cryo-EM reveals organization of the membrane-bound V(O) motor.

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Structure of the Pseudomonas aeruginosa Type IVa Pilus Secretin at 7.4 Å.

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Structure of the mitochondrial ATP synthase by electron cryomicroscopy

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TROSY-based NMR evidence for a novel class of 20S proteasome inhibitors

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The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.

scientific article published on 13 April 2017

The crystal structure of bacteriophage HK97 gp6: defining a large family of head-tail connector proteins

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The human coronavirus HCoV-229E S-protein structure and receptor binding

scientific article published on 25 October 2019

The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture

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The resolution dependence of optimal exposures in liquid nitrogen temperature electron cryomicroscopy of catalase crystals.

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The structural basis of modified nucleosome recognition by 53BP1

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The study of vacuolar-type ATPases by single particle electron microscopy

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Through-grid wicking enables high-speed cryoEM specimen preparation

scientific article published on 13 October 2020

Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy

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Triggered instability of liposomes bound to hydrophobically modified core-shell PNIPAM hydrogel beads

scientific article published in January 2010

Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study

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Validating maps from single particle electron cryomicroscopy

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Vma9p need not be associated with the yeast V-ATPase for fully-coupled proton pumping activity in vitro.

scientific article published on 14 January 2015

YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit

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cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

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